Histological Quantification of Gene Silencing by Intratracheal Administration of Dry Powdered Small-Interfering RNA/Chitosan Complexes in the Murine Lung

Pharmaceutical Research

Volumn 32, Issue 12, 2015, Pages 3877-3885

  Ihara, Daisuke ^a   Hattori, Noboru ^a   Horimasu, Yasushi ^a   Masuda, Takeshi ^a   Nakashima, Taku ^a   Senoo, Tadashi ^a   Iwamoto, Hiroshi ^a   Fujitaka, Kazunori ^a   Okamoto, Hirokazu ^b   Kohno, Nobuoki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b MEIJO UNIVERSITY   (Japan)

Author keywords

airway epithelium; alveolar wall; dry powdered siRNA chitosan complex; intratracheal administration; metastatic lung tumor

Indexed keywords

CHITOSAN; ENHANCED GREEN FLUORESCENT PROTEIN; SMALL INTERFERING RNA; GREEN FLUORESCENT PROTEIN; POWDER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHIOLE; CONTROLLED STUDY; DRY POWDER; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HISTOLOGY; INHALATION; LEWIS CARCINOMA; LEWIS LUNG CARCINOMA CELL; LUNG ALVEOLUS WALL; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CHEMISTRY; GENETICS; INHALATIONAL DRUG ADMINISTRATION; LUNG; LUNG TUMOR; METABOLISM; PATHOLOGY; POWDER; RNA INTERFERENCE; SECONDARY; TRACHEA; TRANSGENIC MOUSE; TUMOR CELL LINE; ULTRASTRUCTURE;

ADMINISTRATION, INHALATION; ANIMALS; CELL LINE, TUMOR; CHITOSAN; FEMALE; GREEN FLUORESCENT PROTEINS; LUNG; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POWDERS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRACHEA;

EID: 84946474305     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-015-1747-6     Document Type: Article

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