Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes

Pharmaceutical Research

Volumn 17, Issue 5, 2000, Pages 521-525

  Dokka, Sujatha ^a   Toledo, David ^b   Shi, Xianglin ^c   Castranova, Vincent ^c   Rojanasakul, Yon ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b SANOFI   (France)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Cationic liposomes; Charge; Reactive oxygen intermediates; Toxicity

Indexed keywords

CATION; LACTATE DEHYDROGENASE; LIPOFECTAMINE; LIPOSOME; OXYGEN RADICAL; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CONTROLLED STUDY; ENZYME ACTIVITY; LUNG LAVAGE; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RESPIRATORY BURST;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CATIONS; CHEMILUMINESCENT MEASUREMENTS; FREE RADICAL SCAVENGERS; L-LACTATE DEHYDROGENASE; LIPOSOMES; LUNG DISEASES; MALE; MICE; MICE, INBRED BALB C; NITROGEN OXIDES; REACTIVE OXYGEN SPECIES;

EID: 0034096243     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007504613351     Document Type: Article

References (15)

1. 1. X. Gao and L. Huang. Cationic liposome-mediated gene transfer. Gene Ther. 2:710-722 (1995).
2. 2. X. Gao and L. Huang. A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochim. Biophys. Res. Commun. 179:280-285 (1991).
3. 3. K. L. Brigham, B. Meyrick, B. Christman, M. Magnusson, G. King, and L. Berry. In vivo transfection of expression of murine lungs with a functioning prokaryotic gene using a liposome vehicle. Am. J. Med. Sci. 298:278-281 (1989).
4. 4. N. J. Caplen, E. W. Alton, P. G. Middleton, J. R. Dorin, B. J. Stevenson, X. Gao, S. R. Durham, P. K. Jefferey, M. E. Hodson, and C. Coutelle. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med. 1:39-46 (1995).
5. 5. G. J. Nabel, E. G. Nabel, Z. Y. Yang, B. A. Fox, G. E. Plautz, X. Gao, L. Huang, S. Shu, D. Gordon, and A. E. Chang. Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. USA 90:11307-11311 (1993).
6. 6. R. K. Scheule, J. A. St. George, R. G. Bagley, J. Marshall, J. M. Kaplan, G. Y. Akita, K. X. Wang, E. R. Lee, D. J. Harris, C. Jiang, N. S. Yew, A. E. Smith, and S. H. Cheng. Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung. Human Gene Ther. 8:689-707 (1997).
7. 7. B. D. Freimark, H. P. Blezinger, V. J. Florack, J. L. Nordstrom, S. D. Long, D. S. Deshpande, S. Nochumson, and K. L. Petrak. Cationic lipids enhance cytokine and cell influx levels in the lung following administration of plasmid: Cationic lipid complexes. J. Immunol. 160:4580-4586 (1998).
8. 8. Y. K. Song, F. Liu, S. Chu, and D. Liu. Characterization of cationic liposome-mediated gene transfer in vivo by intravenous administration. Human Gene Ther. 8:1585-1594 (1997).
9. 9. J. P. Vigneron, N. Oudrhiri, M. Fauquet, L. Vergely, J. C. Bradley, M. Basseville, P. Lehn, and J. M. Lehn. Guanidium-cholesterol cationic lipids: efficient vectors for the transfection of eukaryotic cells. Proc. Natl. Acad. Sci. USA 93:9682-9686 (1996).
10. 10. R. Bottega and R. M. Epand. Inhibition of protein kinase C by cationic amphiphiles. Biochemistry 31:9025-9030 (1992).
11. 11. S. Gossart, C. Cambon, C. Orfila, M. H. Seguelas, J. C. Lepert, J. Rami, and B. Pipy. Reactive oxygen intermediates as regulators of TNF-α production in rat lung inflammation induced by silica. J. Immunol. 156:1550-1548 (1996).
12. 12. J. M. Antonini, K. Vandyke, Z. Ye, M. DiMatteo, and M. J. Reasor. Introduction of luminol-dependent chemiluminescence as a method to study silica inflammation in the tissue and phagocytic cells of rat lung. Environ. Health Persp. 102:37-42 (1994).
13. 13. P. Hawley-Nelson, V. Ciccarone, G. Gebeyehu, and J. Jessee. Lipofectamine reagent: A new, higher efficiency polycationic liposome transfection reagent. Focus 15:73-79 (1993).
14. 14. D. Liu, J. E. Knapp, and Y. K. Song. Mechanism of cationic liposome-mediated transfection of the lung endothelium. In L. Huang, M. C. Hung, and E. Wagner (eds.), Nonviral Vectors for Gene Therapy, Academic Press, New York, 1999, pp. 313-335.
15. 15. H. W. Pogrebniak, M. J. Merino, S. M. Hahn, J. B. Mitchell, and H. I. Pass. Spin trap salvage from endotoxemia: the role of cytokine down-regulation. Surgery 112:130-135 (1992).