메뉴 건너뛰기




Volumn 10, Issue 1, 2016, Pages 129-139

The role of chronic inflammation in the development of gastrointestinal cancers: Reviewing cancer prevention with natural antiinflammatory intervention

Author keywords

Cancer prevention; GI cancer; GI inflammation; Oxidative stress; TGF ; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; LYMPHOTOXIN; TUMOR NECROSIS FACTOR;

EID: 84946434090     PISSN: 17474124     EISSN: 17474132     Source Type: Journal    
DOI: 10.1586/17474124.2016.1103179     Document Type: Review
Times cited : (23)

References (80)
  • 1
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A. Inflammation and cancer: Back to Virchow? Lancet. 2001;357(9255):539-545.
    • (2001) Lancet. , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 2
    • 0015489740 scopus 로고
    • Molecular repair, wound healing, and carcinogenesis: Tumor production a possible overhealing?
    • Haddow A. Molecular repair, wound healing, and carcinogenesis: Tumor production a possible overhealing? Adv Cancer Res. 1972;16:181-234.
    • (1972) Adv Cancer Res. , vol.16 , pp. 181-234
    • Haddow, A.1
  • 3
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak HF. Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med. 1986;315(26):1650-1659.
    • (1986) N Engl J Med. , vol.315 , Issue.26 , pp. 1650-1659
    • Dvorak, H.F.1
  • 4
    • 47749139256 scopus 로고    scopus 로고
    • Cancer as an overhealing wound: An old hypothesis revisited
    • Schafer M, Werner S. Cancer as an overhealing wound: An old hypothesis revisited. Nat Rev Mol Cell Biol. 2008;9 (8):628-638.
    • (2008) Nat Rev Mol Cell Biol. , vol.9 , Issue.8 , pp. 628-638
    • Schafer, M.1    Werner, S.2
  • 5
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell. 2011;144(5):646-674.
    • (2011) Cell. , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • Mantovani A, Allavena P, Sica A, et al. Cancer-related inflammation. Nature. 2008;454(7203):436-444.
    • (2008) Nature. , vol.454 , Issue.7203 , pp. 436-444
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 7
    • 18844382358 scopus 로고    scopus 로고
    • Advances in Barrett's esophagus and esophageal adenocarcinoma
    • Shaheen NJ. Advances in Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology. 2005;128(6):1554-1566.
    • (2005) Gastroenterology. , vol.128 , Issue.6 , pp. 1554-1566
    • Shaheen, N.J.1
  • 8
    • 84930576826 scopus 로고    scopus 로고
    • Barrett's esophagus: Recent insights into pathogenesis and cellular ontogeny
    • Kapoor H, Agrawal DK, Mittal SK. Barrett's esophagus: Recent insights into pathogenesis and cellular ontogeny. Transl Res J Lab Clin Med. 2015;166 (1):28-40.
    • (2015) Transl Res J Lab Clin Med. , vol.166 , Issue.1 , pp. 28-40
    • Kapoor, H.1    Agrawal, D.K.2    Mittal, S.K.3
  • 9
    • 70449502829 scopus 로고    scopus 로고
    • How does inflammation cause Barrett's metaplasia?
    • Colleypriest BJ, Ward SG, Tosh D. How does inflammation cause Barrett's metaplasia? Curr Opin Pharmacol. 2009;9 (6):721-726.
    • (2009) Curr Opin Pharmacol. , vol.9 , Issue.6 , pp. 721-726
    • Colleypriest, B.J.1    Ward, S.G.2    Tosh, D.3
  • 11
    • 84925096803 scopus 로고    scopus 로고
    • Screening for Barrett's esophagus and esophageal adenocarcinoma: Rationale, recent progress, challenges, and future directions
    • Sami SS, Ragunath K, Iyer PG. Screening for Barrett's esophagus and esophageal adenocarcinoma: Rationale, recent progress, challenges, and future directions. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc. 2015;13 (4):623-634.
    • (2015) Clin Gastroenterol Hepatol off Clin Pract J Am Gastroenterol Assoc. , vol.13 , Issue.4 , pp. 623-634
    • Sami, S.S.1    Ragunath, K.2    Iyer, P.G.3
  • 12
    • 72049084000 scopus 로고    scopus 로고
    • Aneuploidy and overexpression of Ki67 and p53 as markers for neoplastic progression in Barrett's esophagus: A casecontrol study
    • Sikkema M, Kerkhof M, Steyerberg EW, et al. Aneuploidy and overexpression of Ki67 and p53 as markers for neoplastic progression in Barrett's esophagus: A casecontrol study. Am J Gastroenterol. 2009;104(11):2673-2680.
    • (2009) Am J Gastroenterol. , vol.104 , Issue.11 , pp. 2673-2680
    • Sikkema, M.1    Kerkhof, M.2    Steyerberg, E.W.3
  • 13
    • 84898906506 scopus 로고    scopus 로고
    • The Korean perspective of Helicobacter pylori infection: Lessons from the Japanese government's policy to prevent gastric cancer
    • Park JM, Hahm KB. The Korean perspective of Helicobacter pylori infection: Lessons from the Japanese government's policy to prevent gastric cancer. Dig Dis. 2014;32(3):290-294.
    • (2014) Dig Dis. , vol.32 , Issue.3 , pp. 290-294
    • Park, J.M.1    Hahm, K.B.2
  • 15
    • 84890923699 scopus 로고    scopus 로고
    • Non-microbial approach for Helicobacter pylori as faster track to prevent gastric cancer than simple eradication
    • Park SH, Kangwan N, Park JM, et al. Non-microbial approach for Helicobacter pylori as faster track to prevent gastric cancer than simple eradication. World J Gastroenterol WJG. 2013;19(47):8986-8995.
    • (2013) World J Gastroenterol WJG. , vol.19 , Issue.47 , pp. 8986-8995
    • Park, S.H.1    Kangwan, N.2    Park, J.M.3
  • 17
    • 84908608590 scopus 로고    scopus 로고
    • The gut microbiota, bacterial metabolites and colorectal cancer
    • Louis P, Hold GL, Flint HJ. The gut microbiota, bacterial metabolites and colorectal cancer. Nat Rev Microbiol. 2014;12(10):661-672.
    • (2014) Nat Rev Microbiol. , vol.12 , Issue.10 , pp. 661-672
    • Louis, P.1    Hold, G.L.2    Flint, H.J.3
  • 18
    • 84875095406 scopus 로고    scopus 로고
    • Chemoprevention of gastrointestinal cancer: The reality and the dream
    • Chun KS, Kim EH, Lee S, et al. Chemoprevention of gastrointestinal cancer: The reality and the dream. Gut Liver. 2013;7(2):137-149.
    • (2013) Gut Liver. , vol.7 , Issue.2 , pp. 137-149
    • Chun, K.S.1    Kim, E.H.2    Lee, S.3
  • 19
    • 84930756978 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids as an angelus custos to rescue patients from NSAID-induced gastroduodenal damage
    • Park JM, Han YM, Jeong M, et al. Omega-3 polyunsaturated fatty acids as an angelus custos to rescue patients from NSAID-induced gastroduodenal damage. J Gastroenterol. 2015;50(6):614-625.
    • (2015) J Gastroenterol. , vol.50 , Issue.6 , pp. 614-625
    • Park, J.M.1    Han, Y.M.2    Jeong, M.3
  • 20
    • 84942063575 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis: A clinical update
    • Williamson KD, Chapman RW. Primary sclerosing cholangitis: A clinical update. Br Med Bull. 2015;114(1):53-64.
    • (2015) Br Med Bull. , vol.114 , Issue.1 , pp. 53-64
    • Williamson, K.D.1    Chapman, R.W.2
  • 22
    • 84929284936 scopus 로고    scopus 로고
    • Clinical presentation, risk factors and staging systems of cholangiocarcinoma
    • Plentz RR, Malek NP. Clinical presentation, risk factors and staging systems of cholangiocarcinoma. Best Pract Res Clin Gastroenterol. 2015;29(2):245-252.
    • (2015) Best Pract Res Clin Gastroenterol. , vol.29 , Issue.2 , pp. 245-252
    • Plentz, R.R.1    Malek, N.P.2
  • 25
    • 85015467225 scopus 로고    scopus 로고
    • New insights in hepatocellular carcinoma: From bench to bedside
    • De Minicis S, Marzioni M, Benedetti A, et al. New insights in hepatocellular carcinoma: From bench to bedside. Ann Transl Med. 2013;1(2):15.
    • (2013) Ann Transl Med. , vol.1 , Issue.2 , pp. 15
    • De Minicis, S.1    Marzioni, M.2    Benedetti, A.3
  • 26
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection. Hepatology. 2010;51(5):1820-1832.
    • (2010) Hepatology. , vol.51 , Issue.5 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 27
    • 7044235603 scopus 로고    scopus 로고
    • Obesity and hepatocellular carcinoma
    • Caldwell SH, Crespo DM, Kang HS, et al. Obesity and hepatocellular carcinoma. Gastroenterology. 2004;127(5 Suppl 1): S97-103.
    • (2004) Gastroenterology. , vol.127 , Issue.5 , pp. 97-103
    • Caldwell, S.H.1    Crespo, D.M.2    Kang, H.S.3
  • 28
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell. 2010;140(6):883-899.
    • (2010) Cell. , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 29
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer. 2009;9(5):361-371.
    • (2009) Nat Rev Cancer. , vol.9 , Issue.5 , pp. 361-371
    • Balkwill, F.1
  • 30
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-kappaB as the matchmaker
    • Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat Immunol. 2011;12 (8):715-723.
    • (2011) Nat Immunol. , vol.12 , Issue.8 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 31
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang D, Dubois RN. Eicosanoids and cancer. Nat Rev Cancer. 2010;10 (3):181-193.
    • (2010) Nat Rev Cancer. , vol.10 , Issue.3 , pp. 181-193
    • Wang, D.1    Dubois, R.N.2
  • 32
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: Linking inflammation and immunity to cancer development and progression
    • Karin M, Greten FR. NF-kappaB: Linking inflammation and immunity to cancer development and progression. Nat Rev Immunol. 2005;5(10):749-759.
    • (2005) Nat Rev Immunol. , vol.5 , Issue.10 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 33
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitisassociated cancer
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitisassociated cancer. Cell. 2004;118(3):285-296.
    • (2004) Cell. , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 34
    • 38849171267 scopus 로고    scopus 로고
    • Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
    • Popivanova BK, Kitamura K, Wu Y, et al. Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest. 2008;118 (2):560-570.
    • (2008) J Clin Invest. , vol.118 , Issue.2 , pp. 560-570
    • Popivanova, B.K.1    Kitamura, K.2    Wu, Y.3
  • 35
    • 0034924028 scopus 로고    scopus 로고
    • Loss of transforming growth factor beta signaling in the intestine contributes to tissue injury in inflammatory bowel disease
    • Hahm KB, Im YH, Parks TW, et al. Loss of transforming growth factor beta signaling in the intestine contributes to tissue injury in inflammatory bowel disease. Gut. 2001;49(2):190-198.
    • (2001) Gut. , vol.49 , Issue.2 , pp. 190-198
    • Hahm, K.B.1    Im, Y.H.2    Parks, T.W.3
  • 36
    • 0042307513 scopus 로고    scopus 로고
    • The two faces of transforming growth factor beta in carcinogenesis
    • Roberts AB, Wakefield LM. The two faces of transforming growth factor beta in carcinogenesis. Proc Natl Acad Sci USA. 2003;100(15):8621-8623.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , Issue.15 , pp. 8621-8623
    • Roberts, A.B.1    Wakefield, L.M.2
  • 37
    • 2642614530 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 is a new formof tumor suppressor with true haploid insufficiency
    • Tang B, Bottinger EP, Jakowlew SB, et al. Transforming growth factor-beta1 is a new formof tumor suppressor with true haploid insufficiency. Nature Medicine. 1998;4 (7):802-807.
    • (1998) Nature Medicine. , vol.4 , Issue.7 , pp. 802-807
    • Tang, B.1    Bottinger, E.P.2    Jakowlew, S.B.3
  • 38
    • 0033565626 scopus 로고    scopus 로고
    • Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis
    • Engle SJ, Hoying JB, Boivin GP, et al. Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. Cancer Res. 1999;59(14):3379-3386.
    • (1999) Cancer Res. , vol.59 , Issue.14 , pp. 3379-3386
    • Engle, S.J.1    Hoying, J.B.2    Boivin, G.P.3
  • 39
    • 84900007855 scopus 로고    scopus 로고
    • Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-beta in gastric tissue
    • Ota M, Horiguchi M, Fang V, et al. Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-beta in gastric tissue. Cancer Res. 2014;74(9):2642-2651.
    • (2014) Cancer Res. , vol.74 , Issue.9 , pp. 2642-2651
    • Ota, M.1    Horiguchi, M.2    Fang, V.3
  • 40
    • 0028785603 scopus 로고
    • Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
    • Parsons R, Myeroff LL, Liu B, et al. Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. Cancer Res. 1995;55(23):5548-5550.
    • (1995) Cancer Res. , vol.55 , Issue.23 , pp. 5548-5550
    • Parsons, R.1    Myeroff, L.L.2    Liu, B.3
  • 41
    • 0042365388 scopus 로고    scopus 로고
    • Conditional loss of TGF-beta signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice
    • Hahm K-B, Lee KM, Kim YB, et al. Conditional loss of TGF-beta signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice. Aliment Pharmacol Ther. 2002;16(Suppl 2):115-127.
    • (2002) Aliment Pharmacol Ther. , vol.16 , pp. 115-127
    • Hahm, K.-B.1    Lee, K.M.2    Kim, Y.B.3
  • 42
    • 0034611611 scopus 로고    scopus 로고
    • Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
    • Xu X, Brodie SG, Yang X, et al. Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene. 2000;19(15):1868-1874.
    • (2000) Oncogene. , vol.19 , Issue.15 , pp. 1868-1874
    • Xu, X.1    Brodie, S.G.2    Yang, X.3
  • 43
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science. 1996;271(5247):350-353.
    • (1996) Science. , vol.271 , Issue.5247 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 44
    • 33745578957 scopus 로고    scopus 로고
    • Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
    • Kim BG, Li C, Qiao W, et al. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Nature. 2006;441(7096):1015-1019.
    • (2006) Nature. , vol.441 , Issue.7096 , pp. 1015-1019
    • Kim, B.G.1    Li, C.2    Qiao, W.3
  • 45
    • 33745515023 scopus 로고    scopus 로고
    • Tumour microenvironment: TGFbeta: The molecular Jekyll and Hyde of cancer
    • Bierie B, Moses HL. Tumour microenvironment: TGFbeta: The molecular Jekyll and Hyde of cancer. Nat Rev Cancer. 2006;6(7):506-520.
    • (2006) Nat Rev Cancer. , vol.6 , Issue.7 , pp. 506-520
    • Bierie, B.1    Moses, H.L.2
  • 46
    • 84877858964 scopus 로고    scopus 로고
    • Hypoxia stimulates the EMT of gastric cancer cells through autocrine TGF signaling
    • Matsuoka J, Yashiro M, Doi Y, et al. Hypoxia stimulates the EMT of gastric cancer cells through autocrine TGF? signaling. Plos One. 2013;8(5):e62310.
    • (2013) Plos One. , vol.8 , Issue.5 , pp. e62310
    • Matsuoka, J.1    Yashiro, M.2    Doi, Y.3
  • 47
    • 33750311251 scopus 로고    scopus 로고
    • Vivo and in vitro evidence for transforming growth factor-beta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma
    • Rees JR, Onwuegbusi BA, Save VE, et al. In vivo and in vitro evidence for transforming growth factor-beta1-mediated epithelial to mesenchymal transition in esophageal adenocarcinoma. Cancer Res. 2006;66(19):9583-9590.
    • (2006) Cancer Res. , vol.66 , Issue.19 , pp. 9583-9590
    • Rees, J.R.1    Onwuegbusi, B.A.2    Save, V.E.3
  • 48
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008;10(5):593-601.
    • (2008) Nat Cell Biol. , vol.10 , Issue.5 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3
  • 49
    • 84925104792 scopus 로고    scopus 로고
    • Oxidatively induced DNA damage and its repair in cancer
    • Dizdaroglu M. Oxidatively induced DNA damage and its repair in cancer. Mutat Res Rev Mutat Res. 2015;763:212-245.
    • (2015) Mutat Res Rev Mutat Res. , vol.763 , pp. 212-245
    • Dizdaroglu, M.1
  • 50
    • 70350243205 scopus 로고    scopus 로고
    • Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance
    • Zhu Y, Hu J, Hu Y, et al. Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance. Cancer Treat Rev. 2009;35(7):590-596.
    • (2009) Cancer Treat Rev. , vol.35 , Issue.7 , pp. 590-596
    • Zhu, Y.1    Hu, J.2    Hu, Y.3
  • 51
    • 34250377983 scopus 로고    scopus 로고
    • Therapeutic potential of drugs to modulate DNA repair in cancer
    • Curtin N. Therapeutic potential of drugs to modulate DNA repair in cancer. Expert Opin Ther Targets. 2007;11 (6):783-799.
    • (2007) Expert Opin Ther Targets. , vol.11 , Issue.6 , pp. 783-799
    • Curtin, N.1
  • 52
    • 84942134314 scopus 로고    scopus 로고
    • Mitochondrialmediated oxidative stress: Old target for new drugs
    • Lyakhovich A, Graifer D. Mitochondrialmediated oxidative stress: Old target for new drugs. Curr Med Chem. 2015;22 (26):3040-3053.
    • (2015) Curr Med Chem. , vol.22 , Issue.26 , pp. 3040-3053
    • Lyakhovich, A.1    Graifer, D.2
  • 53
    • 77951432631 scopus 로고    scopus 로고
    • The causes of cancer revisited: "Mitochondrial malignancy" and ROSinduced oncogenic transformation-why mitochondria are targets for cancer therapy
    • Ralph SJ, Rodriguez-Enriquez S, Neuzil J, et al. The causes of cancer revisited: "mitochondrial malignancy" and ROSinduced oncogenic transformation-why mitochondria are targets for cancer therapy. Mol Asp Med. 2010;31(2):145-170.
    • (2010) Mol Asp Med. , vol.31 , Issue.2 , pp. 145-170
    • Ralph, S.J.1    Rodriguez-Enriquez, S.2    Neuzil, J.3
  • 54
    • 84866665390 scopus 로고    scopus 로고
    • Mitochondria and cancer
    • Wallace DC. Mitochondria and cancer. Nat Rev Cancer. 2012;12(10):685-698.
    • (2012) Nat Rev Cancer. , vol.12 , Issue.10 , pp. 685-698
    • Wallace, D.C.1
  • 55
    • 84911479104 scopus 로고    scopus 로고
    • Oxidative stress and antioxidants in carcinogenesis and integrative therapy of cancer
    • Milkovic L, Siems W, Siems R, et al. Oxidative stress and antioxidants in carcinogenesis and integrative therapy of cancer. Curr Pharm Des. 2014;20 (42):6529-6542.
    • (2014) Curr Pharm Des. , vol.20 , Issue.42 , pp. 6529-6542
    • Milkovic, L.1    Siems, W.2    Siems, R.3
  • 56
    • 34547666680 scopus 로고    scopus 로고
    • Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation
    • Iyer AK, Greish K, Seki T, et al. Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation. J Drug Target. 2007;15(7-8):496-506.
    • (2007) J Drug Target. , vol.15 , Issue.7-8 , pp. 496-506
    • Iyer, A.K.1    Greish, K.2    Seki, T.3
  • 57
    • 84908213474 scopus 로고    scopus 로고
    • Mitochondrial ROS in cancer: Initiators, amplifiers or an Achilles' heel?
    • Sabharwal SS, Schumacker PT. Mitochondrial ROS in cancer: Initiators, amplifiers or an Achilles' heel? Nat Rev Cancer. 2014;14(11):709-721.
    • (2014) Nat Rev Cancer. , vol.14 , Issue.11 , pp. 709-721
    • Sabharwal, S.S.1    Schumacker, P.T.2
  • 58
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F, Burns K, Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10(2):417-426.
    • (2002) Mol Cell. , vol.10 , Issue.2 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 59
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140(6):821-832.
    • (2010) Cell. , vol.140 , Issue.6 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 60
    • 77956905415 scopus 로고    scopus 로고
    • Dual roles for immunity in gastrointestinal cancers
    • Ferrone C, Dranoff G. Dual roles for immunity in gastrointestinal cancers. J Clin Oncol Off J Am Soc Clin Oncol. 2010;28(26):4045-4051.
    • (2010) J Clin Oncol off J Am Soc Clin Oncol. , vol.28 , Issue.26 , pp. 4045-4051
    • Ferrone, C.1    Dranoff, G.2
  • 61
    • 84858643750 scopus 로고    scopus 로고
    • Inflammasomes in carcinogenesis and anticancer immune responses
    • Zitvogel L, Kepp O, Galluzzi L, et al. Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol. 2012;13(4):343-351.
    • (2012) Nat Immunol. , vol.13 , Issue.4 , pp. 343-351
    • Zitvogel, L.1    Kepp, O.2    Galluzzi, L.3
  • 62
    • 84255210700 scopus 로고    scopus 로고
    • Molecular definitions of cell death subroutines: Recommendations of the nomenclature committee on cell death 2012
    • Galluzzi L, Vitale I, Abrams JM, et al. Molecular definitions of cell death subroutines: Recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ. 2012;19 (1):107-120.
    • (2012) Cell Death Differ. , vol.19 , Issue.1 , pp. 107-120
    • Galluzzi, L.1    Vitale, I.2    Abrams, J.M.3
  • 63
    • 54549089856 scopus 로고    scopus 로고
    • Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
    • Tu S, Bhagat G, Cui G, et al. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008;14 (5):408-419.
    • (2008) Cancer Cell. , vol.14 , Issue.5 , pp. 408-419
    • Tu, S.1    Bhagat, G.2    Cui, G.3
  • 64
    • 77952303410 scopus 로고    scopus 로고
    • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
    • Allen IC, TeKippe EM, Woodford RM, et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med. 2010;207(5):1045-1056.
    • (2010) J Exp Med. , vol.207 , Issue.5 , pp. 1045-1056
    • Allen, I.C.1    TeKippe, E.M.2    Woodford, R.M.3
  • 65
    • 0035818549 scopus 로고    scopus 로고
    • IL-1 beta-converting enzyme (caspase-1) in intestinal inflammation
    • Siegmund B, Lehr HA, Fantuzzi G, et al. IL-1 beta-converting enzyme (caspase-1) in intestinal inflammation. Proc Natl Acad Sci USA. 2001;98(23):13249-13254.
    • (2001) Proc Natl Acad Sci USA. , vol.98 , Issue.23 , pp. 13249-13254
    • Siegmund, B.1    Lehr, H.A.2    Fantuzzi, G.3
  • 66
    • 77956128040 scopus 로고    scopus 로고
    • Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
    • Bauer C, Duewell P, Mayer C, et al. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut. 2010;59 (9):1192-1199.
    • (2010) Gut. , vol.59 , Issue.9 , pp. 1192-1199
    • Bauer, C.1    Duewell, P.2    Mayer, C.3
  • 67
    • 79953084107 scopus 로고    scopus 로고
    • The Nlrp3 inflammasome: Contributions to intestinal homeostasis
    • Zaki MH, Lamkanfi M, Kanneganti TD. The Nlrp3 inflammasome: Contributions to intestinal homeostasis. Trends Immunol. 2011;32(4):171-179.
    • (2011) Trends Immunol. , vol.32 , Issue.4 , pp. 171-179
    • Zaki, M.H.1    Lamkanfi, M.2    Kanneganti, T.D.3
  • 68
    • 77949965210 scopus 로고    scopus 로고
    • Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
    • Dupaul-Chicoine J, Yeretssian G, Doiron K, et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity. 2010;32 (3):367-378.
    • (2010) Immunity. , vol.32 , Issue.3 , pp. 367-378
    • Dupaul-Chicoine, J.1    Yeretssian, G.2    Doiron, K.3
  • 69
    • 77955350419 scopus 로고    scopus 로고
    • MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18
    • Salcedo R, Worschech A, Cardone M, et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin 18. J Exp Med. 2010;207(8):1625-1636.
    • (2010) J Exp Med. , vol.207 , Issue.8 , pp. 1625-1636
    • Salcedo, R.1    Worschech, A.2    Cardone, M.3
  • 70
    • 47849098044 scopus 로고    scopus 로고
    • Inflammation: Gearing the journey to cancer
    • Kundu JK, Surh YJ. Inflammation: Gearing the journey to cancer. Mutat Res. 2008;659(1-2):15-30.
    • (2008) Mutat Res. , vol.659 , Issue.1-2 , pp. 15-30
    • Kundu, J.K.1    Surh, Y.J.2
  • 71
    • 84859635458 scopus 로고    scopus 로고
    • Emerging avenues linking inflammation and cancer
    • Kundu JK, Surh Y-J. Emerging avenues linking inflammation and cancer. Free Radic Biol Med. 2012;52(9):2013-2037.
    • (2012) Free Radic Biol Med. , vol.52 , Issue.9 , pp. 2013-2037
    • Kundu, J.K.1    Surh, Y.-J.2
  • 72
    • 84874107358 scopus 로고    scopus 로고
    • Resolution of inflammation as a novel chemopreventive strategy
    • Lee HN, Na HK, Surh YJ. Resolution of inflammation as a novel chemopreventive strategy. Semin Immunopathol. 2013;35 (2):151-161.
    • (2013) Semin Immunopathol. , vol.35 , Issue.2 , pp. 151-161
    • Lee, H.N.1    Na, H.K.2    Surh, Y.J.3
  • 73
    • 46049085866 scopus 로고    scopus 로고
    • NF-kappa B and Nrf2 as potential chemopreventive targets of some antiinflammatory and antioxidative phytonutrients with anti-inflammatory and antioxidative activities
    • Surh YJ. NF-kappa B and Nrf2 as potential chemopreventive targets of some antiinflammatory and antioxidative phytonutrients with anti-inflammatory and antioxidative activities. Asia Pac J Clin Nutr. 2008;17(Suppl 1):269-272.
    • (2008) Asia Pac J Clin Nutr. , vol.17 , pp. 269-272
    • Surh, Y.J.1
  • 74
    • 65449180675 scopus 로고    scopus 로고
    • Colorectal carcinogenesis: Review of human and experimental animal studies
    • Tanaka T. Colorectal carcinogenesis: Review of human and experimental animal studies. J Carcinog. 2009;8:5.
    • (2009) J Carcinog. , vol.8 , pp. 5
    • Tanaka, T.1
  • 75
  • 76
    • 84918800279 scopus 로고    scopus 로고
    • Antioxidative phytoceuticals to ameliorate pancreatitis in animal models: An answer from nature
    • Park JM, Lee S, Chung MK, et al. Antioxidative phytoceuticals to ameliorate pancreatitis in animal models: An answer from nature. World J Gastroenterol WJG. 2014;20(44):16570-16581.
    • (2014) World J Gastroenterol WJG. , vol.20 , Issue.44 , pp. 16570-16581
    • Park, J.M.1    Lee, S.2    Chung, M.K.3
  • 77
    • 84924100580 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids as potential chemopreventive agent for gastrointestinal cancer
    • Park JM, Kwon SH, Han YM, et al. Omega-3 polyunsaturated fatty acids as potential chemopreventive agent for gastrointestinal cancer. J Cancer Prev. 2013;18(3):201-208.
    • (2013) J Cancer Prev. , vol.18 , Issue.3 , pp. 201-208
    • Park, J.M.1    Kwon, S.H.2    Han, Y.M.3
  • 78
    • 84962511881 scopus 로고    scopus 로고
    • Shortterm intervention to revert premalignant lesions as strategy to prevent gastrointestinal cancers
    • Han YM, Park JM, Lee HJ, et al. Shortterm intervention to revert premalignant lesions as strategy to prevent gastrointestinal cancers. J Cancer Prev. 2013;18 (4):289-297.
    • (2013) J Cancer Prev. , vol.18 , Issue.4 , pp. 289-297
    • Han, Y.M.1    Park, J.M.2    Lee, H.J.3
  • 79
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Hong WK, Sporn MB. Recent advances in chemoprevention of cancer. Science. 1997;278(5340):1073-1077.
    • (1997) Science. , vol.278 , Issue.5340 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 80
    • 84923116384 scopus 로고    scopus 로고
    • Chemoquiescence for ideal cancer treatment and prevention where are we now?
    • Kangwan N, Park JM, Kim EH, et al. Chemoquiescence for ideal cancer treatment and prevention: Where are we now? J Cancer Prev. 2014;19:89-96.
    • (2014) J Cancer Prev. , vol.19 , pp. 89-96
    • Kangwan, N.1    Park, J.M.2    Kim, E.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.