Polymeric micelles of zinc protoporphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation

Journal of Drug Targeting

Volumn 15, Issue 7-8, 2007, Pages 496-506

  Iyer, Arun K ^a   Greish, Khaled ^b   Seki, Takahiro ^a   Okazaki, Shoko ^b   Fang, Jun ^b   Takeshita, Keizo ^b   Maeda, Hiroshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b SOJO UNIVERSITY   (Japan)

Author keywords

Antitumor effect; Heme oxygenase 1; Photodynamic therapy; Polyethylene glycol; Styrene maleic acid copolymer; Zinc protoporphyrin

Indexed keywords

BILIRUBIN; BILIVERDIN; CATALASE; DIMETHYLBENZ[A]ANTHRACENE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; MACROGOL; PROTOPORPHYRIN ZINC; SINGLET OXYGEN; STYRENE MALEIC ANHYDRIDE COPOLYMER; SUPEROXIDE DISMUTASE; TUNGSTEN; XENON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BIOCOMPATIBILITY; BREAST CANCER; CANCER CELL CULTURE; CELL KILLING; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG HALF LIFE; DRUG PENETRATION; DRUG POTENTIATION; DRUG RETENTION; DRUG SELECTIVITY; DRUG TARGETING; DRUG TISSUE LEVEL; DRUG TUMOR LEVEL; ENZYME INHIBITION; ESOPHAGUS CANCER; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; ILLUMINATION; IN VITRO STUDY; IN VIVO STUDY; LASER; MACROMOLECULE; MALE; MALIGNANT NEOPLASTIC DISEASE; MICELLE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; RAT; SARCOMA 180; SOLID TUMOR; TREATMENT OUTCOME; TUMOR CELL; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; ENZYME INHIBITORS; FEMALE; HEME OXYGENASE-1; HUMANS; MALE; MICE; MICELLES; NEOPLASMS; PERMEABILITY; PHOTOCHEMOTHERAPY; POLYETHYLENE GLYCOLS; POLYMERS; PROTOPORPHYRINS; RATS; RATS, SPRAGUE-DAWLEY; SINGLET OXYGEN;

EID: 34547666680     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860701498252     Document Type: Article

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