Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation

Haematologica

Volumn 100, Issue 11, 2015, Pages 1442-1450

  Kunz, Joachim B ^a,b,c   Rausch, Tobias ^b   Bandapalli, Obul R ^a,b,c   Eilers, Juliane ^a,b   Pechanska, Paulina ^a,b   Schuessele, Stephanie ^a,b   Assenov, Yassen ^c   Stütz, Adrian M ^b   Kirschner Schwabe, Renate ^d   Hof, Jana ^c,d   Eckert, Cornelia ^d   von Stackelberg, Arend ^d   Schrappe, Martin ^e   Stanulla, Martin ^f   Koehler, Rolf ^a   Avigad, Smadar ^g   Elitzur, Sarah ^g   Handgretinger, Rupert ^h   Benes, Vladimir ^b   Weischenfeldt, Joachim ^b   Korbel, Jan O ^b   Muckenthaler, Martina U ^a,b   Kulozik, Andreas E ^a,b,c   more..

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^f HANNOVER MEDICAL SCHOOL   (Germany)

^g SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

^h UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; DNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CANCER GROWTH; CELL SELECTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISORDERS OF DNA SYNTHESIS AND REPAIR; DNA METHYLATION; EPIGENETICS; FEMALE; GENE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC ANALYSIS; HUMAN; LEUKEMIA RELAPSE; LEUKEMOGENESIS; MALE; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; MUTATION; NT5C2 GENE; SCHOOL CHILD; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SMARCA4 GENE; SUZ12 GENE; WHSC1 GENE; ADOLESCENT; CLINICAL TRIAL; GENETICS; METABOLISM; MULTICENTER STUDY; PATHOLOGY; PRESCHOOL CHILD; PROMOTER REGION;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DNA METHYLATION; DNA, NEOPLASM; FEMALE; HUMANS; MALE; MUTATION; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROMOTER REGIONS, GENETIC;

EID: 84946239254     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2015.129692     Document Type: Article

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