Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia

Nature Communications

Volumn 6, Issue , 2015, Pages

  Ma, Xiaotu ^a   Edmonson, Michael ^a   Yergeau, Donald ^a   Muzny, Donna M ^b   Hampton, Oliver A ^b   Rusch, Michael ^a   Song, Guangchun ^a   Easton, John ^a   Harvey, Richard C ^c   Wheeler, David A ^b   Ma, Jing ^a   Doddapaneni, Harshavardhan ^b   Vadodaria, Bhavin ^a   Wu, Gang ^a   Nagahawatte, Panduka ^a   Carroll, William L ^d   Chen, I Ming ^c   Gastier Foster, Julie M ^e,f   Relling, Mary V ^a   Smith, Malcolm A ^g   Devidas, Meenakshi ^h   Auvil, Jaime M Guidry ^g   Downing, James R ^a   Loh, Mignon L ⁱ   Willman, Cheryl L ^c   Gerhard, Daniela S ^a   Mullighan, Charles G ^a   Hunger, Stephen P ^j   Zhang, Jinghui ^a   more..

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^e NATIONWIDE CHILDREN S HOSPITAL   (United States)

^f OHIO STATE UNIVERSITY   (United States)

^g NATIONAL CANCER INSTITUTE   (United States)

^h UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CLONE; DISEASE INCIDENCE; GENETIC VARIATION; MUTATION; SURVIVORSHIP;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CANCER DIAGNOSIS; CANCER SURVIVAL; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; CLONAL ARCHITECTURE; CLONAL EVOLUTION; CLONAL VARIATION; CLONING; CONTROLLED STUDY; COPY NUMBER VARIATION; CREBBP GENE; GENETIC HETEROGENEITY; HUMAN; IKZF1 GENE; LEUKEMIA RELAPSE; MUTATION RATE; MUTATOR GENE; NT5C2 GENE; ONCOGENE N RAS; SEQUENCE ANALYSIS; SOMATIC MUTATION; TP53 GENE; TUMOR GENE; USH2A GENE; WHOLE EXOME SEQUENCING; WHSC1 GENE; CELL CLONE; DISEASE COURSE; EXOME; FEMALE; GENETICS; MALE; MUTATION; TUMOR RECURRENCE;

5' NUCLEOTIDASE; CREBBP PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; HISTONE LYSINE METHYLTRANSFERASE; IKAROS TRANSCRIPTION FACTOR; IKZF1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NRAS PROTEIN, HUMAN; NT5C2 PROTEIN, HUMAN; PROTEIN P53; REPRESSOR PROTEIN; SCLEROPROTEIN; TP53 PROTEIN, HUMAN; USH2A PROTEIN, HUMAN; WHSC1 PROTEIN, HUMAN;

5'-NUCLEOTIDASE; CHILD; CLONAL EVOLUTION; CLONE CELLS; CREB-BINDING PROTEIN; DISEASE PROGRESSION; DNA COPY NUMBER VARIATIONS; EXOME; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GTP PHOSPHOHYDROLASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; IKAROS TRANSCRIPTION FACTOR; MALE; MEMBRANE PROTEINS; MUTATION; NEOPLASM RECURRENCE, LOCAL; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84925235093     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7604     Document Type: Article

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