D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

Amino Acids

Volumn 47, Issue 12, 2015, Pages 2505-2519

  Di Grazia, Antonio ^a   Cappiello, Floriana ^a   Cohen, Hadar ^b   Casciaro, Bruno ^a   Luca, Vincenzo ^a   Pini, Alessandro ^c   Di, Y Peter ^d   Shai, Yechiel ^b   Mangoni, Maria Luisa ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c UNIVERSITY OF SIENA   (Italy)

^d UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Anti biofilm activity; Antimicrobial peptide; Diastereomer; Esculentin 1; Wound healing

Indexed keywords

ANTIBIOTIC AGENT; BACTERIUM LIPOPOLYSACCHARIDE; ESCULENTIN 1A (1-21) AMIDE; ESCULENTIN DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WOUND HEALING PROMOTING AGENT; AMINO ACID; AMPHIBIAN PROTEIN; ANTIMICROBIAL CATIONIC PEPTIDE; ESCULENTIN PROTEIN, RANA ESCULENTA; LIPOPOLYSACCHARIDE;

ALPHA HELIX; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANURA; ARTICLE; BACTERIAL STRAIN; BIOFILM; CELL MIGRATION; CELL VIABILITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY TEST; DIASTEREOISOMER; DRUG DESIGN; DRUG STABILITY; HUMAN; HUMAN CELL; IMMUNOMODULATION; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SKIN; WOUND HEALING; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CELL MOTION; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; LUNG ALVEOLUS; MACROPHAGE; MICROBIAL SENSITIVITY TEST; PROTEIN TERTIARY STRUCTURE; RANIDAE; RAW 264.7 CELL LINE; STEREOISOMERISM; SYNTHESIS;

AMINO ACID SEQUENCE; AMINO ACIDS; AMPHIBIAN PROTEINS; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOFILMS; CELL LINE; CELL MOVEMENT; CELL SURVIVAL; CIRCULAR DICHROISM; EPITHELIAL CELLS; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; PULMONARY ALVEOLI; RANIDAE; RAW 264.7 CELLS; SKIN; STEREOISOMERISM;

EID: 84946204620     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-015-2041-y     Document Type: Article

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