Structure-activity relationship, conformational and biological studies of temporin l analogues

Journal of Medicinal Chemistry

Volumn 54, Issue 5, 2011, Pages 1298-1307

  Mangoni, Maria Luisa ^c   Carotenuto, Alfonso ^a   Auriemma, Luigia ^a   Saviello, Maria Rosaria ^a   Campiglia, Pietro ^b   Gomez Monterrey, Isabel ^a   Malfi, Stefania ^a   Marcellini, Ludovica ^c   Barra, Donatella ^c   Novellino, Ettore ^a   Grieco, Paolo ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRO TEMPORIN L; POLYPEPTIDE ANTIBIOTIC AGENT; RETROINVERSE TEMPORIN L; TEMPORIN L 1; TEMPORIN L 2; TEMPORIN L DERIVATIVE; TEMPORIN L[10 LEUCINE]; TEMPORIN L[11 LYSINE]; TEMPORIN L[11 ORNITHINE]; TEMPORIN L[2 LEUCINE 3 PROLINE]; TEMPORIN L[3 ARGININE 7 ARGININE]; TEMPORIN L[3 ARGININE]; TEMPORIN L[3 PROLINE 10 DEXTRO PROLINE]; TEMPORIN L[3 PROLINE 10 PROLINE]; TEMPORIN L[3 PROLINE 11 ORNITHINE]; TEMPORIN L[3 PROLINE]; TEMPORIN L[7 ARGININE]; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ACINETOBACTER JUNII; ALPHA HELIX; AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; DRUG CONFORMATION; DRUG DESIGN; DRUG SYNTHESIS; ENTEROBACTER FAECALIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEMOLYSIS; MINIMUM INHIBITORY CONCENTRATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS SYRINGAE; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS CAPITIS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PYOGENES; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMPHIBIAN PROTEINS; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; HEMOLYSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICROBIAL SENSITIVITY TESTS; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79952261984     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1012853     Document Type: Article

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