-
1
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, et al. (2008) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127:2893-2917.
-
(2008)
Int J Cancer
, vol.127
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
-
2
-
-
84856020870
-
Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma
-
22138044
-
Gao J, Inagaki Y, Song P, Qu X, Kokudo N, et al. (2012) Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma. Pharmacol Res 65:23-30. doi: 10.1016/j.phrs.2011.11.011 PMID: 22138044
-
(2012)
Pharmacol Res
, vol.65
, pp. 23-30
-
-
Gao, J.1
Inagaki, Y.2
Song, P.3
Qu, X.4
Kokudo, N.5
-
3
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
16929323
-
Farazi PA, DePinho RA (2006) Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 6:674-687. doi: 10.1038/nrc1934 PMID: 16929323
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
4
-
-
71249126197
-
Management of hepatocellular carcinoma in Asia: Consensus statement from the Asian Oncology Summit 2009
-
19880065
-
Poon D, Anderson BO, Chen LT, Tanaka K, Lau WY, et al. (2009) Management of hepatocellular carcinoma in Asia: consensus statement from the Asian Oncology Summit 2009. Lancet Oncol 10:1111-1118. doi: 10.1016/S1470-2045 (09) 70241-4 PMID: 19880065
-
(2009)
Lancet Oncol
, vol.10
, pp. 1111-1118
-
-
Poon, D.1
Anderson, B.O.2
Chen, L.T.3
Tanaka, K.4
Lau, W.Y.5
-
5
-
-
28844480321
-
Management of hepatocellular carcinoma
-
16250051
-
Bruix J, Sherman M (2005) Management of hepatocellular carcinoma. Hepatology 42:1208-1236. doi: 10.1002/hep. 20933 PMID: 16250051
-
(2005)
Hepatology
, vol.42
, pp. 1208-1236
-
-
Bruix, J.1
Sherman, M.2
-
6
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
18650514
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, et al. (2008) Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359:378-390. doi: 10.1056/NEJMoa0708857 PMID: 18650514
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
-
7
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, doubleblind, placebo-controlled trial
-
19095497
-
Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, et al. (2009) Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, doubleblind, placebo-controlled trial. Lancet Oncol 10:25-34. doi: 10.1016/S1470-2045 (08) 70285-7 PMID: 19095497
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
-
8
-
-
84858658381
-
EASL-EORTC clinical practice guidelines: Management of hepatocellular carcinoma
-
22424438
-
Llovet JM, Ducreux M, Lencioni R, Di Bisceglie AM, Galle PR, et al. (2012) EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. J Hepatol 56:908-943. doi: 10.1016/j.jhep. 2011.12.001 PMID: 22424438
-
(2012)
J Hepatol
, vol.56
, pp. 908-943
-
-
Llovet, J.M.1
Ducreux, M.2
Lencioni, R.3
Di Bisceglie, A.M.4
Galle, P.R.5
-
9
-
-
84864480565
-
Molecularly targeted therapy for advanced hepatocellular carcinoma in 2012: Current status and future perspectives
-
22846866
-
Zhu AX (2012) Molecularly targeted therapy for advanced hepatocellular carcinoma in 2012: current status and future perspectives. Semin Oncol 39:493-502. doi: 10.1053/j.seminoncol.2012.05.014 PMID: 22846866
-
(2012)
Semin Oncol
, vol.39
, pp. 493-502
-
-
Zhu, A.X.1
-
10
-
-
84884327551
-
Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma
-
23898367
-
Zhai B, Sun XY (2013) Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma. World J Hepatol 5:345-352. doi: 10.4254/wjh.v5.i7.345 PMID: 23898367
-
(2013)
World J Hepatol
, vol.5
, pp. 345-352
-
-
Zhai, B.1
Sun, X.Y.2
-
11
-
-
7044229778
-
Primary liver cancer: Worldwide incidence and trends
-
15508102
-
Bosch FX, Ribes J, Diaz M, Cleries R (2004) Primary liver cancer: worldwide incidence and trends. Gastroenterology 127:S5-S16. doi: 10.1053/j.gastro.2004.07.015 PMID: 15508102
-
(2004)
Gastroenterology
, vol.127
, pp. S5-S16
-
-
Bosch, F.X.1
Ribes, J.2
Diaz, M.3
Cleries, R.4
-
12
-
-
11144356989
-
A decade's studies on metastasis of hepatocellular carcinoma
-
14685850
-
Tang ZY, Ye SL, Liu YK, Qin LX, Sun HC, et al. (2004) A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol 130:187-196. doi: 10.1007/s00432-003-0511-1 PMID: 14685850
-
(2004)
J Cancer Res Clin Oncol
, vol.130
, pp. 187-196
-
-
Tang, Z.Y.1
Ye, S.L.2
Liu, Y.K.3
Qin, L.X.4
Sun, H.C.5
-
13
-
-
33751252276
-
Cancer metastasis: Building a framework
-
17110329
-
Gupta GP, Massague J (2006) Cancer metastasis: building a framework. Cell 127:679-695. doi: 10. 1016/j.cell.2006.11.001 PMID: 17110329
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
14
-
-
0035902141
-
The microenvironment of the tumour-host interface
-
11357145
-
Liotta LA, Kohn EC (2001) The microenvironment of the tumour-host interface. Nature 411:375-379. doi: 10.1038/35077241 PMID: 11357145
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
15
-
-
33745297408
-
New signals from the invasive front
-
16724056
-
Christofori G (2006) New signals from the invasive front. Nature 441:444-450. doi: 10.1038/nature04872 PMID: 16724056
-
(2006)
Nature
, vol.441
, pp. 444-450
-
-
Christofori, G.1
-
16
-
-
19644395911
-
HGF/SF-Met signaling in tumor progression
-
15686627
-
Gao CF, Vande Woude GF (2005) HGF/SF-Met signaling in tumor progression. Cell Res 15:49-51. doi: 10.1038/sj.cr.7290264 PMID: 15686627
-
(2005)
Cell Res
, vol.15
, pp. 49-51
-
-
Gao, C.F.1
Vande Woude, G.F.2
-
17
-
-
84856454999
-
TGF-beta in the bone microenvironment: Role in breast cancer metastases
-
21748439
-
Buijs JT, Stayrook KR, Guise TA (2011) TGF-beta in the Bone Microenvironment: Role in Breast Cancer Metastases. Cancer Microenviron 4:261-281. doi: 10.1007/s12307-011-0075-6 PMID: 21748439
-
(2011)
Cancer Microenviron
, vol.4
, pp. 261-281
-
-
Buijs, J.T.1
Stayrook, K.R.2
Guise, T.A.3
-
19
-
-
0030951358
-
Expression of hepatocyte growth factor and its receptor c-met proto-oncogene in hepatocellular carcinoma
-
9096589
-
Ueki T, Fujimoto J, Suzuki T, Yamamoto H, Okamoto E (1997) Expression of hepatocyte growth factor and its receptor c-met proto-oncogene in hepatocellular carcinoma. Hepatology 25:862-866. doi: 10. 1002/hep. 510250413 PMID: 9096589
-
(1997)
Hepatology
, vol.25
, pp. 862-866
-
-
Ueki, T.1
Fujimoto, J.2
Suzuki, T.3
Yamamoto, H.4
Okamoto, E.5
-
20
-
-
44349155339
-
Clinical significance of serum HGF and c-Met expression in tumor tissue for evaluation of properties and treatment of hepatocellular carcinoma
-
18613405
-
Osada S, Kanematsu M, Imai H, Goshima S (2008) Clinical significance of serum HGF and c-Met expression in tumor tissue for evaluation of properties and treatment of hepatocellular carcinoma. Hepatogastroenterology 55:544-549. PMID: 18613405
-
(2008)
Hepatogastroenterology
, vol.55
, pp. 544-549
-
-
Osada, S.1
Kanematsu, M.2
Imai, H.3
Goshima, S.4
-
21
-
-
61949226823
-
Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma
-
19065669
-
Ke AW, Shi GM, Zhou J, Wu FZ, Ding ZB, et al. (2009) Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma. Hepatology 49:491-503. doi: 10.1002/hep. 22639 PMID: 19065669
-
(2009)
Hepatology
, vol.49
, pp. 491-503
-
-
Ke, A.W.1
Shi, G.M.2
Zhou, J.3
Wu, F.Z.4
Ding, Z.B.5
-
22
-
-
47749103018
-
Prognostic factors and recurrence of small hepatocellular carcinoma after hepatic resection or microwave ablation: A retrospective study
-
17943391
-
Wang ZL, Liang P, Dong BW, Yu XL, Yu de J (2008) Prognostic factors and recurrence of small hepatocellular carcinoma after hepatic resection or microwave ablation: a retrospective study. J Gastrointest Surg 12:327-337. doi: 10.1007/s11605-007-0310-0 PMID: 17943391
-
(2008)
J Gastrointest Surg
, vol.12
, pp. 327-337
-
-
Wang, Z.L.1
Liang, P.2
Dong, B.W.3
Yu, X.L.4
De, J.Y.5
-
23
-
-
67649882024
-
Comparative genomic classification of human hepatocellular carcinoma
-
19318328
-
Kaposi-Novak P (2009) Comparative genomic classification of human hepatocellular carcinoma. Magy Onkol 53:61-67. doi: 10.1556/MOnkol.53.2009.1.9 PMID: 19318328
-
(2009)
Magy Onkol
, vol.53
, pp. 61-67
-
-
Kaposi-Novak, P.1
-
24
-
-
82355185942
-
Hepatocyte growth factor upregulation promotes carcinogenesis and epithelialmesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways
-
21744257
-
Ogunwobi OO, Liu C (2011) Hepatocyte growth factor upregulation promotes carcinogenesis and epithelialmesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways. Clin Exp Metastasis 28:721-731. doi: 10.1007/s10585-011-9404-x PMID: 21744257
-
(2011)
Clin Exp Metastasis
, vol.28
, pp. 721-731
-
-
Ogunwobi, O.O.1
Liu, C.2
-
25
-
-
0034811355
-
Invasiveness of hepatocellular carcinoma cell lines: Contribution of hepatocyte growth factor, c-met, and transcription factor Ets-1
-
11527416
-
Jiang Y, Xu W, Lu J, He F, Yang X (2001) Invasiveness of hepatocellular carcinoma cell lines: contribution of hepatocyte growth factor, c-met, and transcription factor Ets-1. Biochem Biophys Res Commun 286:1123-1130. doi: 10.1006/bbrc.2001.5521 PMID: 11527416
-
(2001)
Biochem Biophys Res Commun
, vol.286
, pp. 1123-1130
-
-
Jiang, Y.1
Xu, W.2
Lu, J.3
He, F.4
Yang, X.5
-
26
-
-
84863116289
-
Cyclooxygenase-2 and Akt mediate multiple growth-factorinduced epithelial-mesenchymal transition in human hepatocellular carcinoma
-
22097969
-
Ogunwobi OO, Wang T, Zhang L, Liu C (2012) Cyclooxygenase-2 and Akt mediate multiple growth-factorinduced epithelial-mesenchymal transition in human hepatocellular carcinoma. J Gastroenterol Hepatol 27:566-578. doi: 10.1111/j.1440-1746.2011.06980.x PMID: 22097969
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 566-578
-
-
Ogunwobi, O.O.1
Wang, T.2
Zhang, L.3
Liu, C.4
-
27
-
-
84875552108
-
Targeting the HGF/c-MET pathway in hepatocellular carcinoma
-
23388504
-
Goyal L, Muzumdar MD, Zhu AX (2013) Targeting the HGF/c-MET pathway in hepatocellular carcinoma. Clin Cancer Res 19:2310-2318. doi: 10.1158/1078-0432. CCR-12-2791 PMID: 23388504
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2310-2318
-
-
Goyal, L.1
Muzumdar, M.D.2
Zhu, A.X.3
-
28
-
-
80052033164
-
C-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma
-
21618573
-
You H, Ding W, Dang H, Jiang Y, Rountree CB (2011) c-Met represents a potential therapeutic target for personalized treatment in hepatocellular carcinoma. Hepatology 54:879-889. doi: 10.1002/hep. 24450 PMID: 21618573
-
(2011)
Hepatology
, vol.54
, pp. 879-889
-
-
You, H.1
Ding, W.2
Dang, H.3
Jiang, Y.4
Rountree, C.B.5
-
29
-
-
84860240078
-
Targeted therapy of hepatocellular carcinoma: Present and future
-
22369685
-
Chan SL, Yeo W (2012) Targeted therapy of hepatocellular carcinoma: present and future. J Gastroenterol Hepatol 27:862-872. doi: 10.1111/j.1440-1746.2012.07096.x PMID: 22369685
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 862-872
-
-
Chan, S.L.1
Yeo, W.2
-
30
-
-
0029007694
-
The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein
-
7731718
-
Pelicci G, Giordano S, Zhen Z, Salcini AE, Lanfrancone L, et al. (1995) The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein. Oncogene 10:1631-1638. PMID: 7731718
-
(1995)
Oncogene
, vol.10
, pp. 1631-1638
-
-
Pelicci, G.1
Giordano, S.2
Zhen, Z.3
Salcini, A.E.4
Lanfrancone, L.5
-
31
-
-
0028351702
-
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
-
7513258
-
Ponzetto C, Bardelli A, Zhen Z, Maina F, dalla Zonca P, et al. (1994) A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77:261-271. doi: 10.1016/0092-8674 (94) 90318-2 PMID: 7513258
-
(1994)
Cell
, vol.77
, pp. 261-271
-
-
Ponzetto, C.1
Bardelli, A.2
Zhen, Z.3
Maina, F.4
Dalla Zonca, P.5
-
32
-
-
78649420006
-
MET signalling: Principles and functions in development, organ regeneration and cancer
-
21102609
-
Trusolino L, Bertotti A, Comoglio PM (2010) MET signalling: principles and functions in development, organ regeneration and cancer. Nat Rev Mol Cell Biol 11:834-848. doi: 10.1038/nrm3012 PMID: 21102609
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 834-848
-
-
Trusolino, L.1
Bertotti, A.2
Comoglio, P.M.3
-
33
-
-
84892773921
-
C-MET kinase inhibitors: A patent review (2011-2013)
-
24266843
-
Zhu K, Kong X, Zhao D, Liang Z, Luo C (2014) c-MET kinase inhibitors: a patent review (2011-2013). Expert Opin Ther Pat 24:217-230. doi: 10.1517/13543776.2014.864279 PMID: 24266843
-
(2014)
Expert Opin Ther Pat
, vol.24
, pp. 217-230
-
-
Zhu, K.1
Kong, X.2
Zhao, D.3
Liang, Z.4
Luo, C.5
-
34
-
-
84870227233
-
Pharmacokinetic drivers of toxicity for basic molecules: Strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor
-
23142475
-
Diaz D, Ford KA, Hartley DP, Harstad EB, Cain GR, et al. (2013) Pharmacokinetic drivers of toxicity for basic molecules: strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor. Toxicol Appl Pharmacol 266:86-94. doi: 10.1016/j.taap. 2012.10.026 PMID: 23142475
-
(2013)
Toxicol Appl Pharmacol
, vol.266
, pp. 86-94
-
-
Diaz, D.1
Ford, K.A.2
Hartley, D.P.3
Harstad, E.B.4
Cain, G.R.5
-
35
-
-
84872600260
-
A Phase-1b study of tivantinib (ARQ 197) in adult patients with hepatocellular carcinoma and cirrhosis
-
23287988
-
Santoro A, Simonelli M, Rodriguez-Lope C, Zucali P, Camacho LH, et al. (2013) A Phase-1b study of tivantinib (ARQ 197) in adult patients with hepatocellular carcinoma and cirrhosis. Br J Cancer 108:21-24. doi: 10.1038/bjc.2012.556 PMID: 23287988
-
(2013)
Br J Cancer
, vol.108
, pp. 21-24
-
-
Santoro, A.1
Simonelli, M.2
Rodriguez-Lope, C.3
Zucali, P.4
Camacho, L.H.5
-
36
-
-
60749105811
-
Functional expression of LZ-8, a fungal immunomodulatory protein from Ganoderma lucidium in Pichia pastoris
-
19164882
-
Xue Q, Ding Y, Shang C, Jiang C, Zhao M (2008) Functional expression of LZ-8, a fungal immunomodulatory protein from Ganoderma lucidium in Pichia pastoris. J Gen Appl Microbiol 54:393-398. doi: 10. 2323/jgam.54.393 PMID: 19164882
-
(2008)
J Gen Appl Microbiol
, vol.54
, pp. 393-398
-
-
Xue, Q.1
Ding, Y.2
Shang, C.3
Jiang, C.4
Zhao, M.5
-
37
-
-
70349184084
-
An immunomodulatory protein, Ling Zhi-8, induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and MAPK pathways
-
19498044
-
Lin YL, Liang YC, Tseng YS, Huang HY, Chou SY, et al. (2009) An immunomodulatory protein, Ling Zhi-8, induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and MAPK pathways. J Leukoc Biol 86:877-889. doi: 10.1189/jlb.0708441 PMID: 19498044
-
(2009)
J Leukoc Biol
, vol.86
, pp. 877-889
-
-
Lin, Y.L.1
Liang, Y.C.2
Tseng, Y.S.3
Huang, H.Y.4
Chou, S.Y.5
-
38
-
-
85027957698
-
A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells
-
21499904
-
Lin CC, Yu YL, Shih CC, Liu KJ, Ou KL, et al. (2011) A novel adjuvant Ling Zhi-8 enhances the efficacy of DNA cancer vaccine by activating dendritic cells. Cancer Immunol Immunother 60:1019-1027. doi: 10.1007/s00262-011-1016-4 PMID: 21499904
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1019-1027
-
-
Lin, C.C.1
Yu, Y.L.2
Shih, C.C.3
Liu, K.J.4
Ou, K.L.5
-
39
-
-
80053636271
-
Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer
-
21888505
-
Martinez-Montemayor MM, Acevedo RR, Otero-Franqui E, Cubano LA, Dharmawardhane SF (2011) Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancer. Nutr Cancer 63:1085-1094. doi: 10.1080/01635581.2011.601845 PMID: 21888505
-
(2011)
Nutr Cancer
, vol.63
, pp. 1085-1094
-
-
Martinez-Montemayor, M.M.1
Acevedo, R.R.2
Otero-Franqui, E.3
Cubano, L.A.4
Dharmawardhane, S.F.5
-
40
-
-
33645457460
-
Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line
-
16402390
-
Liao CH, Hsiao YM, Hsu CP, Lin MY, Wang JC, et al. (2006) Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line. Mol Carcinog 45:220-229. doi: 10.1002/mc.20161 PMID: 16402390
-
(2006)
Mol Carcinog
, vol.45
, pp. 220-229
-
-
Liao, C.H.1
Hsiao, Y.M.2
Hsu, C.P.3
Lin, M.Y.4
Wang, J.C.5
-
41
-
-
81855206545
-
Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway
-
21983128
-
Wu CT, Lin TY, Hsu HY, Sheu F, Ho CM, et al. (2011) Ling Zhi-8 mediates p53-dependent growth arrest of lung cancer cells proliferation via the ribosomal protein S7-MDM2-p53 pathway. Carcinogenesis 32:1890-1896. doi: 10.1093/carcin/bgr221 PMID: 21983128
-
(2011)
Carcinogenesis
, vol.32
, pp. 1890-1896
-
-
Wu, C.T.1
Lin, T.Y.2
Hsu, H.Y.3
Sheu, F.4
Ho, C.M.5
-
42
-
-
38449120142
-
Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae
-
17913967
-
Wang PH, Yang SF, Chen GD, Han CP, Chen SC, et al. (2007) Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae. Reprod Sci 14:475-485. doi: 10.1177/1933719107305035 PMID: 17913967
-
(2007)
Reprod Sci
, vol.14
, pp. 475-485
-
-
Wang, P.H.1
Yang, S.F.2
Chen, G.D.3
Han, C.P.4
Chen, S.C.5
-
43
-
-
35348877300
-
Nuclear translocation of telomerase reverse transcriptase and calcium signaling in repression of telomerase activity in human lung cancer cells by fungal immunomodulatory protein from Ganoderma tsugae
-
17720143
-
Liao CH, Hsiao YM, Sheu GT, Chang JT, Wang PH, et al. (2007) Nuclear translocation of telomerase reverse transcriptase and calcium signaling in repression of telomerase activity in human lung cancer cells by fungal immunomodulatory protein from Ganoderma tsugae. Biochem Pharmacol 74:1541-1554. doi: 10.1016/j.bcp. 2007.07.025 PMID: 17720143
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1541-1554
-
-
Liao, C.H.1
Hsiao, Y.M.2
Sheu, G.T.3
Chang, J.T.4
Wang, P.H.5
-
44
-
-
39149092413
-
Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells
-
18189229
-
Hsu HY, Hua KF, Wu WC, Hsu J, Weng ST, et al. (2008) Reishi immuno-modulation protein induces interleukin-2 expression via protein kinase-dependent signaling pathways within human T cells. J Cell Physiol 215:15-26. doi: 10.1002/jcp. 21144 PMID: 18189229
-
(2008)
J Cell Physiol
, vol.215
, pp. 15-26
-
-
Hsu, H.Y.1
Hua, K.F.2
Wu, W.C.3
Hsu, J.4
Weng, S.T.5
-
45
-
-
84876347074
-
PKC mediates fluctuant ERK-paxillin signaling for hepatocyte growth factor-induced migration of hepatoma cell HepG2
-
23524339
-
Hu CT, Cheng CC, Pan SM, Wu JR, Wu WS (2013) PKC mediates fluctuant ERK-paxillin signaling for hepatocyte growth factor-induced migration of hepatoma cell HepG2. Cell Signal 25:1457-1467. doi: 10.1016/j.cellsig.2013.03.011 PMID: 23524339
-
(2013)
Cell Signal
, vol.25
, pp. 1457-1467
-
-
Hu, C.T.1
Cheng, C.C.2
Pan, S.M.3
Wu, J.R.4
Wu, W.S.5
-
46
-
-
84874040548
-
First-in-man phase I study of GC33, a novel recombinant humanized antibody against glypican-3, in patients with advanced hepatocellular carcinoma
-
23362325
-
Zhu AX, Gold PJ, El-Khoueiry AB, Abrams TA, Morikawa H, et al. (2013) First-in-man phase I study of GC33, a novel recombinant humanized antibody against glypican-3, in patients with advanced hepatocellular carcinoma. Clin Cancer Res 19:920-928. doi: 10.1158/1078-0432. CCR-12-2616 PMID: 23362325
-
(2013)
Clin Cancer Res
, vol.19
, pp. 920-928
-
-
Zhu, A.X.1
Gold, P.J.2
El-Khoueiry, A.B.3
Abrams, T.A.4
Morikawa, H.5
-
47
-
-
79952036568
-
Mitogen-activated protein kinases in hepatocellular carcinoma development
-
20969960
-
Min L, He B, Hui L (2011) Mitogen-activated protein kinases in hepatocellular carcinoma development. Semin Cancer Biol 21:10-20. doi: 10.1016/j.semcancer.2010.10.011 PMID: 20969960
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 10-20
-
-
Min, L.1
He, B.2
Hui, L.3
-
48
-
-
84869790015
-
Signaling pathway/molecular targets and new targeted agents under development in hepatocellular carcinoma
-
23155330
-
Kudo M (2012) Signaling pathway/molecular targets and new targeted agents under development in hepatocellular carcinoma. World J Gastroenterol 18:6005-6017. doi: 10.3748/wjg.v18.i42.6005 PMID: 23155330
-
(2012)
World J Gastroenterol
, vol.18
, pp. 6005-6017
-
-
Kudo, M.1
-
49
-
-
84655165076
-
Inhibition of JNK1 expression decreases migration and invasion of mouse hepatocellular carcinoma cell line in vitro
-
20490718
-
Zhang YH, Wang SQ, Sun CR, Wang M, Wang B, et al. (2011) Inhibition of JNK1 expression decreases migration and invasion of mouse hepatocellular carcinoma cell line in vitro. Med Oncol 28:966-972. doi: 10.1007/s12032-010-9568-2 PMID: 20490718
-
(2011)
Med Oncol
, vol.28
, pp. 966-972
-
-
Zhang, Y.H.1
Wang, S.Q.2
Sun, C.R.3
Wang, M.4
Wang, B.5
-
50
-
-
84879856767
-
ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines
-
23549785
-
Radtke S, Milanovic M, Rosse C, De Rycker M, Lachmann S, et al. (2013) ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines. J Cell Sci 126:2381-2391. doi: 10.1242/jcs.115832 PMID: 23549785
-
(2013)
J Cell Sci
, vol.126
, pp. 2381-2391
-
-
Radtke, S.1
Milanovic, M.2
Rosse, C.3
De Rycker, M.4
Lachmann, S.5
-
51
-
-
84899745281
-
Celastrol blocks interleukin-6 gene expression via downregulation of NF-kappaB in prostate carcinoma cells
-
24664372
-
Chiang KC, Tsui KH, Chung LC, Yeh CN, Chen WT, et al. (2014) Celastrol blocks interleukin-6 gene expression via downregulation of NF-kappaB in prostate carcinoma cells. PLoS One 9:e93151. doi: 10.1371/journal.pone.0093151 PMID: 24664372
-
(2014)
PLoS One
, vol.9
, pp. e93151
-
-
Chiang, K.C.1
Tsui, K.H.2
Chung, L.C.3
Yeh, C.N.4
Chen, W.T.5
-
52
-
-
84897011458
-
Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells
-
24641402
-
Li T, Xu WS, Wu GS, Chen XP, Wang YT, et al. (2014) Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells. Asian Pac J Cancer Prev 15:1745-1749. PMID: 24641402
-
(2014)
Asian Pac J Cancer Prev
, vol.15
, pp. 1745-1749
-
-
Li, T.1
Xu, W.S.2
Wu, G.S.3
Chen, X.P.4
Wang, Y.T.5
-
53
-
-
84864083256
-
Heat shock protein 27 mediates the effect of 1, 3, 5-trihydroxy-13, 13-dimethyl-2H-pyran [7, 6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma
-
22677112
-
Fu WM, Zhang JF, Wang H, Xi ZC, Wang WM, et al. (2012) Heat shock protein 27 mediates the effect of 1, 3, 5-trihydroxy-13, 13-dimethyl-2H-pyran [7, 6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma. J Proteomics 75:4833-4843. doi: 10.1016/j.jprot.2012.05.032 PMID: 22677112
-
(2012)
J Proteomics
, vol.75
, pp. 4833-4843
-
-
Fu, W.M.1
Zhang, J.F.2
Wang, H.3
Xi, Z.C.4
Wang, W.M.5
-
54
-
-
58549114916
-
MiR-34a inhibits migration and invasion by downregulation of c-Met expression in human hepatocellular carcinoma cells
-
19006648
-
Li N, Fu H, Tie Y, Hu Z, Kong W, et al. (2009) miR-34a inhibits migration and invasion by downregulation of c-Met expression in human hepatocellular carcinoma cells. Cancer Lett 275:44-53. doi: 10.1016/j.canlet.2008.09.035 PMID: 19006648
-
(2009)
Cancer Lett
, vol.275
, pp. 44-53
-
-
Li, N.1
Fu, H.2
Tie, Y.3
Hu, Z.4
Kong, W.5
-
55
-
-
65549097632
-
MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells
-
19490101
-
Salvi A, Sabelli C, Moncini S, Venturin M, Arici B, et al. (2009) MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells. Febs J 276:2966-2982. doi: 10.1111/j.1742-4658.2009.07014.x PMID: 19490101
-
(2009)
Febs J
, vol.276
, pp. 2966-2982
-
-
Salvi, A.1
Sabelli, C.2
Moncini, S.3
Venturin, M.4
Arici, B.5
-
56
-
-
27644488740
-
Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo
-
16227408
-
Zhang SZ, Pan FY, Xu JF, Yuan J, Guo SY, et al. (2005) Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo. Mol Cancer Ther 4:1577-1584. doi: 10.1158/1535-7163. MCT-05-0106 PMID: 16227408
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1577-1584
-
-
Zhang, S.Z.1
Pan, F.Y.2
Xu, J.F.3
Yuan, J.4
Guo, S.Y.5
-
57
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
16908937
-
Abou-Alfa GK, Schwartz L, Ricci S, Amadori D, Santoro A, et al. (2006) Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 24:4293-4300. doi: 10.1200/JCO. 2005.01.3441 PMID: 16908937
-
(2006)
J Clin Oncol
, vol.24
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
Amadori, D.4
Santoro, A.5
-
58
-
-
79955433548
-
Targeted therapies for hepatocellular carcinoma
-
21406195
-
Villanueva A, Llovet JM (2011) Targeted therapies for hepatocellular carcinoma. Gastroenterology 140:1410-1426. doi: 10.1053/j.gastro.2011.03.006 PMID: 21406195
-
(2011)
Gastroenterology
, vol.140
, pp. 1410-1426
-
-
Villanueva, A.1
Llovet, J.M.2
-
59
-
-
84862027112
-
Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma
-
22596232
-
Hagiwara S, Kudo M, Nagai T, Inoue T, Ueshima K, et al. (2012) Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma. Br J Cancer 106:1997-2003. doi: 10.1038/bjc.2012.145 PMID: 22596232
-
(2012)
Br J Cancer
, vol.106
, pp. 1997-2003
-
-
Hagiwara, S.1
Kudo, M.2
Nagai, T.3
Inoue, T.4
Ueshima, K.5
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