Targeting c-Met as a promising strategy for the treatment of hepatocellular carcinoma

Pharmacological Research

Volumn 65, Issue 1, 2012, Pages 23-30

  Gao, Jianjun ^a,b   Inagaki, Yoshinori ^b,c   Song, Peipei ^b   Qu, Xianjun ^a   Kokudo, Norihiro ^b   Tang, Wei ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

c Met; Des carboxy prothrombin; Hepatocellular carcinoma; Molecular target therapy; Receptor tyrosine kinase

Indexed keywords

ADAPTOR PROTEIN; DECARBOXYPROTHROMBIN; FORETINIB; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; PROTEIN GAB 1; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; TIVANTINIB; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER LOCALIZATION; CANCER STAGING; CELL ADHESION; DISEASE ASSOCIATION; DOWN REGULATION; DRUG EFFICACY; DRUG PROTEIN BINDING; HUMAN; LIVER CELL CARCINOMA; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; MOLECULARLY TARGETED THERAPY; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; DRUG DESIGN; HUMANS; LIVER NEOPLASMS; MOLECULAR TARGETED THERAPY; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-MET; SIGNAL TRANSDUCTION; TREATMENT OUTCOME;

EID: 84856020870     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.11.011     Document Type: Review

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