Antiacetylcholinesterase and cytotoxic activities of Egyptian propolis with correlation to its GC/MS and HPLC Analysis

International Journal of Pharmaceutical Sciences Review and Research

Volumn 34, Issue 2, 2015, Pages 32-42

  El Hady, Faten K Abd ^a   Souleman, Ahmed M A ^a   El Shahid, Zeinab A ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Acetylcholinesterase inhibitors; Chemical Composition; Cytotoxic activity; GC MS and HPLC analysis; Propolis

Indexed keywords

ALIPHATIC ACID ESTER; ALIPHATIC CARBOXYLIC ACID; CAFFEIC ACID PHENETHYL ESTER; CHEMICAL COMPOUND; CHOLINESTERASE INHIBITOR; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; GALANGIN; GENISTEIN; ISOFLAVONE DERIVATIVE; NATURAL PRODUCT; PHENOL DERIVATIVE; PHENOLIC ACID; PHENOLIC ACID ESTER; PINOCEMBRINE; PROPOLIS; QUERCETIN; TERPENE; TRITERPENOID; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARCINOMA CELL LINE; CELL SURVIVAL; CHEMICAL COMPOSITION; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DPPH RADICAL SCAVENGING ASSAY; EGYPTIAN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC50; MASS FRAGMENTOGRAPHY; OXIDATIVE STRESS;

EID: 84946060113     PISSN: 0976044X     EISSN: 0976044X     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Marques F, Sousa J C, Sousa N, and Palha JA. Blood-brainbarriers in aging and in Alzheimer's disease, Molecular Neurodegeneration, 8,2013,38 http://www.molecularneurodegeneration.com/content/8/ 1/38
2. Abd El-Hady FK, Shaker KH, Imhoff JF., Zinecker H, Salah NM., Ibrahim AM. "Bioactive Metabolites from Propolis Inhibit Superoxide Anion Radical, Acetylcholinesterase and Phosphodiesterase (PDE4)." Int. J. Pharm. Sci. Rev. Res., 21(1), 2013, 338-344.
3. Sacan O and Yanardag R. "Antioxidant and antiacetylcholinesterase activities of chard (Beta vulgaris L. var. cicla)." Food ChemToxicol, 48, 2010, 1275-80.
4. Lee SH, Sancheti SA, Bafna MR, Sancheti SS, Seo SY. "Acetylcholineterase inhibitory and antioxidant properties of Rhododendron yedoense var. Poukhanense bark." J Med Plant Res, 5, 2011, 248-54.
5. Valencia D, Alday E, Robles-Zepeda R, Garibay-Escobar A, Galvez-Ruiz JC, Salas-Reves M, Jimenez-Estrada M, Velazquez-Contreras E, Hernandez J, Velazquez C, Seasonal effect on chemical composition and biological activities of Soronan propolis. Food Chem, 131, 2012, 645-651.
6. Mohammadzadeh S, Shariatpanahi M, Hamedi M, Ahmadkhaniha R, Samadi N, Ostad SN. "Chemical composition, oral toxicity and antimicrobial activity of Iranian propolis." Food Chem, 103, 2007, 1097-1103.
7. Yang SZ, Peng LT, Su XJ, Chen F, Cheng YJ, Fan G and Pan SY. "Bioassay-guided isolation and identification of antifungal components from propolis against Penicilliumitalicum. Food Chem, 127, 2011, 210-215.
8. Hegazi AG, Abd El Hady FK and ShalabyHA. "An in vitro effect of propolis on adult worms of Fasciola gigantic." Vet Parasitol, 144, 2007, 279-286.
9. Abd El-HadyFK, Hegazi AG and Wollenweber E." Effect of Egyptian propolis on the susceptibility of LDL to oxidative modification and antiviral activity with special emphasis on chemical composition." Z. Naturforsch, 62c, 2007, 645-655.
10. Banskota AH, Tezuka Y and Kadota S. "Recent progress in pharmacological research of propolis." Phytother Res, 15, 2001, 561-571.
11. Carvalho AA, Finger D, Machado CS, Schmidt EM, Costa PM, Alves APNN, Morais TMF, de Queiroz MGR, Quinaia SP, da Rosa MR, dos Santos JMT, Pessoa C, de Moraes MO, Costa-Lotufo LV, Sawaya ACHF, Eberlin MN, Torres YR: In vivo antitumoural activity and composition of oil extract of Brazilian propolis. Food Chem, 126, 2011, 1239-1245.
12. Bankova V, Galabov A S, Antonova D, Vilhelmova N and Di PerriB. "Chemical composition of Propolis Extract ACF® and activity against herpes simplex virus, Phytomedicine, 21, 2014, 1432-1438.
13. Usia T, Banskota AH, Tezuka Y, Midorikawa K, Matsushige K, and Kadota S. "Constituents of Chinese propolis and their antiproliferative activities." J Nat Prod, 65, 2002, 673- 676.
14. Suzuki I, Hayashi I, Takaki T, Groveman DS, and Fujimiya Y. "Antitumor and Anticytopenic Effects of Aqueous Extracts of Propolis in Combination with Chemotherapeutic Agents." Cancer Biother Radiopharm, 17, 2002, 553-562.
15. Christov R, Bankova V, Hegazi AG, Abd El-Hady FK and Popov S. "Chemical composition of Egyptian propolis." Z. Naturforsch. 53c, 1998, 197-200.
16. Gil M I, Ferreres F, Ortiz A, Subra E, and Tomàs-Barberàn FA. "Plant phenolic metabolites and floral origin of Rosemary honey." J. Agric. Food Chem., 43, 1995, 2833D2838.
17. Ogan K. and Katz E. "Liquid chromatographic separation of alkyl phenols with fluorescence and ultraviolet detection." Anal. Chem., 53, 1981, 160D163.
18. Matsushige K, Basnet P, Kadota S, and Namba T. "Potent free radical scavenging activity of dicaffeoylquinic acid derivatives from propolis." J. Trad. Med. 13, 1996, 217D228.
19. Khan I, Nisar M, Khan N, Saeed M, Nadeem S, Rehman FU, Karim N, Kaleem WA, Qayum M, Ahmad H, Khan IA. "Structural insights to investigate conypododiol as a dual cholinesterase inhibitor from Asparagus adscendens. Fitoterapea. 81, 2010, 1020-25.
20. Abd El-Hady FK, Abdel-Aziz MS, Shaker KH, El-Shahid ZA, A.Ghani MA. "Coral-Derived Fungi Inhibit Acetyl cholinesterase, Superoxide Anion Radical, and Microbial Activities." Int. J. Pharm. Sci. Rev. Res., 26, 2014, 301-308.
21. Vichai V and Kirtikara K, Sulforhodamine B. "colorimetric assay for cytotoxicity screening. Nat. Protoc., 1(3), 2006, 1112-1116.
22. Hegazi AG, Abd El Hady FK and Shalaby HA. "Inhibitory Effect of Egyptian Propolis on Fasciolagigantica Eggs with Reference to its Effect on Clostridium oedematiens and Correlation to Chemical Composition., Pakistan Journal of Biological Sciences. 10(19), 2007, 3295-3305.
23. Hegazi AG, Abd El Hady FK, Abd Allah F. "Chemical composition and antimicrobial activity of European propolis, Z. Naturforsch., 55C, 2000, 70-75.
24. Hegazi, A. G. and Abd El Hady FK. "Egyptian propolis: 1- Antimicrobial activity and chemical composition of Upper Egypt propolis. Z. Naturforsch., 56c, 2001, 82-88.
25. Abd El Hady FK and Hegazi AG. "Egyptian propolis: 2- Chemical composition, antiviral and antimicrobial activities of East Nile Delta propolis." Z. Naturforsch, 57c, 2002, 386- 394.
26. Hegazi, A. G. and Abd El HadyFK. "Egyptian propolis: 3- Antioxidant, antimicrobial activity and chemical composition of propolis from reclaimed land. Z. Naturforsch, 57c, 2002, 395-402.
27. Abd El-HadyFK, Abdou AM and Abdel-Aziz MS." Isolation, Identification and Evaluation of Antimicrobial and Cytotoxic Activities of the Marine Fungus Aspergillus unguis RSPG_204, Int. J. Pharm. Sci. Rev. Res., 28(2), 2014, 121- 127.
28. Hegazi AG, Abd El Hady FK, Shaker KH, Modear N and Houcine S. "Inhibitory Effect of Algerian propolis on LDL peroxidation, viral and microbial infection with correlation to its chemical composition. MELLIFERA, 12-23, 2012, 2-11, HARUM.
29. Abd El-Hady FK, El Hawary S, Shaker KH, Salah NM." Antioxidant Activity of Flavonoids from Egyptian Propolis, Egyptian J. Biomed.lSci, 34, 2010, 260-273.
30. Abd El-Hady FK, El Awdan SA, Ibrahim AM." Anti-Ulcerative Potential of Egyptian Propolis against Oxidative Gastric Injury Induced by Indomethacin in Rats, Asian J. Med. Pharm. Res., 3(2), 2013, 35-42.
31. Abd El-Hady FK, Arif MH, Eissa AMF, Shaker KH, Hegazi AG, Ibrahim AM." Investigation of In Vitro Superoxide Scavenging Activity of Flavonoids isolated from Egyptian Propolis. Egyptian J. Biomedical Sci., 34, 2010, 26-39.
32. Abd El-Hady FK and Shaker KH." Honey Protects Human Low Density Lipoprotein (LDL) from Peroxidation (In - Vitro), Int. J. Pharm. Sci. Rev. Res., 23(2), 2013, 191-197.
33. Hegazi AG and Abd El-Hady FK. "Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation In vitro, Evidence-based Complementary and Alternative Medicine (eCAM), 6(1), 2009, 113-121.
34. Abd El-Hady FK, Abdel-Aziz MS, Shaker KH and El-Shahid ZA. "Tyrosinase, Acetylcholinesterase Inhibitory Potential, Antioxidant and Antimicrobial Activities of Sponge Derived Fungi with correlation to their GC/MS Analysis." Int. J. Pharm. Sci. Rev. Res., 26(2), 2014, 338-345.
35. Abd El-Hady FK, Abdel-Aziz MS, Shaker KH, El-Shahid ZA and Ibrahim LS. "Antioxidant, Acetylcholinesterase and α- Glucosidase Potentials of Metabolites from the Marine Fungus Aspergillus unguis RSPG_204 Associated with the Sponge (Agelassp.)." Int. J. Pharm. Sci. Rev. Res., 30(1), 2015, 272-278.
36. Borrelli F, Posadas I, Capasso R, Aviello G, Ascione V and Capasso F. "Effect of caffeic acid phenethyl ester on gastric acid secretion in vitro." Eur J Pharmacol, 521(1-3), 2005, 139-43.
37. Ozkan U, Osun A, Basarslan K, Senol S, Kaplan I and Alp H. "Effects of intralipid and caffeic acid phenethyl ester on neurotoxicity, oxidative stress and acetylcholinesterase activity in acute chlorpyriphos intoxication." Int J ClinExp Med, 7(4), 2014, 837-846.
38. Szwajgier D and Borowiec K. "Phenolic acids from malt are efficient acetylcholinesterase and butyrylcholinesterase inhibitors." J. Inst. Brew., 118, 2012, 40-48.
39. Liu R, Li J-z, Song J-k, Zhou D, Huang C, Bai X-y, Xie T, Zhang X, Li Y-j, Wu C-x, Zhang L, Li L, Zhang T-t, Du G-h. "Pinocembrin improves cognition and protects the neurovascular unit in Alzheimer related deficits. Neurobiology of Aging, 35, 2014, 1275-1285.
40. Guo, A J Y, Xie H Q, Choi R C Y, Zheng K Y Z, Bi C W C, Xu S L, Dong T T X, Tsim K W K. "Galangin, a flavonol derived from RhizomaAlpiniaeOfficinarum, inhibits acetylcholinesterase activity in vitro. Chemico-Biological Interactions, 2010, 187(1-3), 246-248.
41. Orhana I, Kartal M, Tosun F and Ener BS. "Screening of Various Phenolic Acids and Flavonoid Derivatives for their Anticholinesterase Potential." Z. Naturforsch., 62c, 2007, 829-832.
42. Min BS, Cuong TD, Lee JS, Shin BS, Woo MH and Hung TM. "Cholinesterase inhibitors from Cleistocalyxoperculatus buds, Arch Pharm Res, 33(10), 2010, 1665-70.
43. Xie Y, Yang W, Chen X and Xiao J. "Inhibition of flavonoids on acetylcholine esterase: binding and structure-activity relationship." Food Funct., 5, 2014, 2582-2589.
44. Teerasripreecha D, Phuwapraisirisan P, Puthong S, Kimura K, Okuyama M, Mori H, Kimura A and Chanchao C. "In vitro antiproliferative/cytotoxic activity on cancer cell lines of a cardanol and a cardol enriched from Thai Apismellifera propolis. BMC Complementary and Alternative Medicine, 2012, 12:27. http://www.biomedcentral.com/1472- 6882/12/27
45. Oršolić N A. "review of propolis antitumour action in-vivo and in-vitro." Journal of ApiProduct and ApiMedical Science, 2(1), 2010, 1-20. DOI 10.3896/IBRA.4.02.1.01.