Recent progress in pharmacological research of propolis

Phytotherapy Research

Volumn 15, Issue 7, 2001, Pages 561-571

  Banskota, Arjun H ^a   Tezuka, Yasuhiro ^a   Kadota, Shigetoshi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Antiinflammatory activity; Antimicrobial activity; Antioxidative activity; Antitumour activity; Hepatoprotective activity; Propolis

Indexed keywords

15 ACETOXYISOCUPRESSIC ACID; 2,2 DIMETHYL 8 PRENYLBENZOPYRAN 6 PROPENOIC ACID; 3 [2,3 DIHYDRO 2 (1 METHYLETHENYL) 7 PRENYL 5 BENZOFURANYL] 2 PROPENOIC ACID; 3,5,7 TRIHYDROXY 4' METHOXYFLAVANOL; 4 DIHYDROCINNAMOYLOXY 3 PRENYLCINNAMIC ACID; 4 HYDROXY 3 PRENYLCINNAMIC ACID; AGATHIC ACID; ALPHA TOCOPHEROL; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; ARTEPILLIN C; BETULETOL; CAFFEIC ACID PHENETHYL ESTER; CUPRESSIC ACID; CYTOTOXIC AGENT; ERMANIN; FLUOROURACIL; ISOCUPRESSIC ACID; KAEMPFERIDE; LIVER PROTECTIVE AGENT; NATURAL PRODUCT; PARACETAMOL; PLANT EXTRACT; PMS 1; PROPOLIS; QUINIC ACID; SYMPHORETICULIC ACID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALLERGY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; DRUG EFFECT; HERBAL MEDICINE; LIVER PROTECTION; NONHUMAN; PHYTOCHEMISTRY; REVIEW;

ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; HUMANS; PHYTOTHERAPY; PROPOLIS; PROTECTIVE AGENTS;

EID: 0034753678     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1029     Document Type: Review

References (113)

1. Heavy metals in propolis: Practical and simple procedures to reduce the lead in the Brazilian propolis
2. Antimicrobial activity of propolis
3. Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: Synthesis, biological evaluation, and molecular modeling
4. Seasonal variations of the chemical composition of Brazilian propolis
5. Phytochemical evidence for the plant origin of Brazilian propolis from Sao Paulo state
6. Chemical composition and antibacterial activity of Brazilian propolis
7. Propolis: Recent advances in chemistry and plant origin
8. Antibacterial diterpenic acids from Brazilian propolis
9. Biological evaluation of propolis from Brazil, Peru, the Netherlands and China
10. Hepatoprotective and anti-Helicobacter pylori activities of constituents from Brazilian propolis
11. Two novel cytotoxic benzofuran derivatives from Brazilian propolis
12. Chemical constituents of Brazilian propolis and their cytotoxic activity
13. Four di-O-caffeoyl quinic acid derivatives from propolis. Potent hepatoprotective activity in experimental liver injury models
14. Potent free radical scavenging activity of propol isolated from Brazilian propolis
15. Review of the biological properties and toxicity of bee propolis (propolis)
16. Hydroxylated aromatic inhibitors of HIV-1 integrase
17. Antifungal activity of Apulia region propolis
18. Anti-hyperalgesic effect of an ethanolic extract of propolis in mice and rats
19. Effects of different formulations of propolis on mice infected with Trypanosoma cruzi
20. Antioxidant activity of a Sardinian propolis
21. Inhibitory effect of caffeic acid phenethyl ester on human leukemia HL-60 cells
22. Apoptosis induced by propolis in human hepatocellular carcinoma cell line
23. Antibacterial furofuran lignans from Canary Islands propolis
24. Antiapoptotic effects of propolis extract and propol on human macrophages exposed to minimally modified low density lipoprotein
25. Hepatoprotective effect of lipid flower pollen extract in paracetamol-induced hepatotoxicity in mice
26. Galactosamine hepatitis: Key role of the nucleotide deficiency period in the pathogenesis of cell injury and cell death
27. Determination of Fe, Mn, Zn, and Cu in an ethanolic extract of Cuban propolis
28. Early, reversible plasma membrane injury in galactosamine-induced liver cell death
29. Anticomplement activity of lysine complexes of propolis phenolic constituents and their synthetic analogs
30. Use of propolis and ultragriseofulvin to inhibit aflatoxigenic fungi
31. Propolis: A review
32. Hepatoprotective effects of propolis extract on paracetamol-induced liver damage in mice
33. Hepatoprotective effects of propolis extract on carbon tetrachloride-induced liver injury in rats
34. Referential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis
35. Suppression of HIV-1 replication by propolis and its immunoregulatory effect
36. Anti-Helicobacter pylori compounds in Brazilian propolis
37. Isolation of antioxidative compounds from Brazilian propolis: 3,4-Dihydroxy-5-prenylcinnamic acid, a novel potent antioxidant
38. Chemical composition and antimicrobial activity of European propolis
39. Caffeic acid phenethyl ester to inhibit posterior capsule opacification in rabbits
40. Topically applied water extract of propolis to suppress corneal neovascularization in rabbits
41. Enhanced cytotoxicity in a Z-photoisomer of a benzopyran derivative of propolis
42. Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 10-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells
43. The effects of caffeic acid phenethyl ester (CAPE) on spinal cordischemia/reperfusion injury in rabbits
44. Immunomodulatory action of propolis. VI. Influence of water soluble derivative on complement activity in vivo
45. Caffeic acid phenethyl ester stimulates human antioxidant response element-mediated expression of the NAD(P)H:quinone oxidoreductase (NQ01) gene
46. Post-initiation effects of a super critical extract of propolis in a rat two-stage carcinogenesis model in female F344 rats
47. Apoptosis and supression of tumor growth by artepillin C extracted from Brazilian propolis
48. Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats
49. Effect of a new variety of Apis mellifera propolis on mutans Streptococci
50. In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens
51. Inhibition of neutrophils chemiluminescence by ethanol extract of propolis (EEP) and phenolic components
52. Antibacterial, antifungal and antiviral activity of propolis of different geographical origin
53. Antipsoriatic, anti-inflammatory, and analgesic effects of an extract of red propolis
54. Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells
55. Caffeic acid phenethyl ester profoundly modifies protein synthesis profile in type 5 adenovirus-transformed cloned rat embryo fibroblast cells
56. The influence of propolis ethanol extract on liver microsomal enzymes and glutathione after chronic alcohol administration
57. Plant phenolics decrease intestinal tumours in an animal model of familial adenomatous polyposis
58. The protective effect of aqueous propolis extract on isolated rat hepatocytes against carbon tetrachloride toxicity
59. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kB and activated protein-1
60. Propolis: Chemical composition, biological properties and therapeutic activity
61. Phenolic compounds from Brazilian propolis with pharmacologiocal activities
62. Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: The effect of anti-inflammatory agents
63. A new clerodane diterpenoid isolated from propolis
64. Preferential cytotoxicity to tumor cells of 3,5-diprenyl-4-hydroxycinnamic acid (artepillin C) isolated from propolis
65. Isolation and characterization of cytotoxic diterpenoid isomers from propolis
66. Antitumor benzopyran derivative of propolis
67. A new benzo-γ-pyran derivative isolated from propolis
68. Quality evaluation of propolis. 1. A comparative study on radical scavenging effects of propolis and vespae nidus
69. Potent free radical scavenging activity of dicaffeoyl quinic acid derivatives from propolis
70. Propolis protects pancreatic β-cells against toxicity of streptozotocin (STZ)
71. Use of propolis and ethyl alcohol in the control of Salmonella in poultry rations (Portuguese)
72. Mouse ear edema modulation by different propolis ethanol extracts
73. 4 in rats
74. The effect of propolis and its components on eicosanoid production during inflammatory response
75. Antimicrobial action of propolis and its components, the effects on growth membrane potential, and motility of bacteria
76. Lipophilic derivatives of caffeic acid as lipoxygenase inhibitors with antioxidant properties
77. Effects of a new clerodane diterpenoid isolated from propolis on chemically induced skin tumours in mice
78. Evaluation of propolis. I. Evaluation of Brazilian and Chinese propolis by enzymatic and physicochemical methods
79. Evaluation of propolis (II). Effects of Brazilian and Chinese propolis on histamine release from rat peritoneal mast cells induced by compound 48/80 and concanavalin A
80. Comparison of the free radical scavenging activity of propolis from several regions of Argentina
81. Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line
82. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation on nuclear transcription factor NF-κB
83. Screening of antibacterial activity of Amaicha del Valle (Tucuman, Argentina) propolis
84. Antibacterial activity of traditional medicines and an active constituent lupulone from Humulus lupulus against Helicobacter pylori
85. Effects of some probable antioxidants on selenite-induced cataract formation and oxidative stress-related parameters in rats
86. Antioxidative activity of extracts from propolis
87. Antioxidative activity of extracts from propolis
88. The effect of propolis extract in experimental chemical corneal injury
89. Anti-inflammatory activity of propolis
90. Antimicrobial activity of propolis on oral micro-organisms
91. Hepatoprotective effect of the Cuban red propolis on the toxicity induced in mice by the administration of acetaminophen
92. Protective effects of propolis extract on allyl alcohol-induced liver injury in mice
93. Effects of Cuban red propolis on galactosamine-induced hepatitis in rats
94. A polyisoprenylated benzophenone from Cuban propolis
95. Synergism between ethanolic extract of propolis (EEP) and anti-tuberculosis drugs on growth of mycobacteria
96. A study on the bacteriostatic activity of propolis
97. Seasonal effect on Brazilian propolis antibacterial activity
98. Protective role of propolis against alcohol-carbon tetrachloride-induced hepatotoxicity in rats
99. Necrogenic action of carbon tetrachloride in rat: A speculative mechanism based on activation
100. The role of intracellular oxidants in apoptosis
101. Preliminary investigation on the anti-inflammatory and anti-microbial activities of propolis
102. Apoptosis mediates the selective toxicity of caffeic acid phenethyl ester (CAPE) toward oncogene-transformed rat embryo fibroblast cells
103. Effect of propolis extract on D-galactosamine-induced hepatic injury in rats
104. In vivo antioxidative activity of propolis evaluated by the interaction with vitamins C and E and the level of lipid hydroperoxides in rats
105. Anti-tumor effect of immunologically active fractions obtained from Brazilian propolis, given in combination with anticancer drug in Ehrlich carcinoma bearing mice
106. The effect against antitumor and recovery of leukopenia by combined use of water soluble propolis and antitumor drug (5-FU)
107. Isolation and identification of compounds from Brazilian propolis which enhance macrophase spreading and mobility
108. Immunotoxicology of host-response-mediated experimental liver injury
109. Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice
110. Phytochemical evidence for botanical origin of tropical propolis from Venezuela
111. Phytochemical, morphological, and biological investigations of propolis from Central Chile
112. Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways