MiR-208a stimulates the cocktail of SOX2 and β-catenin to inhibit the let-7 induction of self-renewal repression of breast cancer stem cells and formed miR208a/let-7 feedback loop via LIN28 and DICER1

Oncotarget

Volumn 6, Issue 32, 2015, Pages 32944-32954

  Sun, Xin ^a   Jiang, Shiwen ^b   Liu, Jian ^a   Wang, Huangzhen ^a   Zhang, Yiwen ^a   Tang, Shou Ching ^c,d   Wang, Jichang ^a   Du, Ning ^a   Xu, Chongwen ^a   Wang, Chenguang ^e   Qin, Sida ^a   Zhang, Jia ^a   Liu, Dapeng ^a   Zhang, Yunfeng ^a   Li, Xiaojun ^a   Wang, Jiansheng ^a   Dong, Jun ^f   Wang, Xin ^a   Xu, Shaohua ^g   Tao, Zhen ^h   Xu, Fei ⁱ   Zhou, Jie ^j   Wang, Tao ^k   Ren, Hong ^a   more..

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d TIANJIN MEDICAL UNIVERSITY   (China)

^e PEKING UNION MEDICAL COLLEGE   (China)

^f THE SECOND AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^g TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^h KEY LABORATORY OF CANCER PREVENTION AND THERAPY   (China)

ⁱ FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

^j GUANGZHOU MEDICAL UNIVERSITY   (China)

^k HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

more..

Author keywords

Breast tumor; Cancer stem cells; Feedback loop; Let 7a; MiRNA 208a

Indexed keywords

BETA CATENIN; DICER; DICER 1; MICRORNA; MICRORNA 208A; MICRORNA LET 7A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LIN28; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; CTNNB1 PROTEIN, HUMAN; DEAD BOX PROTEIN; DICER1 PROTEIN, HUMAN; LIN-28 PROTEIN, HUMAN; MIRN208 MICRORNA, HUMAN; MIRNLET7 MICRORNA, HUMAN; RIBONUCLEASE III; RNA BINDING PROTEIN; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR SOX;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER STAGING; CELL ISOLATION; CELL RENEWAL; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN FUNCTION; BREAST TUMOR; CANCER STEM CELL; FEMALE; GENETIC TRANSFECTION; GENETICS; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

BETA CATENIN; BREAST NEOPLASMS; DEAD-BOX RNA HELICASES; FEMALE; HUMANS; MCF-7 CELLS; MICRORNAS; NEOPLASTIC STEM CELLS; RIBONUCLEASE III; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84946023413     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5079     Document Type: Article

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