Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Sun, Ying ^a   Wang, Yunshan ^b,c   Fan, Cong ^a   Gao, Peng ^b   Wang, Xiuwen ^a   Wei, Guangwei ^b   Wei, Junmin ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c SHANDONG UNIVERSITY   (China)

Author keywords

Epithelial mesenchymal transition; Estrogen; Shh; Sonic hedgehog

Indexed keywords

ALDH1 PROTEIN; BMI1 PROTEIN; CD24 ANTIGEN; CYCLOPAMINE; DOXYCYCLINE; ESTROGEN; MESSENGER RNA; PROTEIN; PROTEIN PATCHED 1; SHORT HAIRPIN RNA; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; ALDEHYDE DEHYDROGENASE ISOENZYME 1; BMI1 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; ESTROGEN RECEPTOR; GLI1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; ISOENZYME; NANOG PROTEIN, HUMAN; PATCHED RECEPTORS; RETINAL DEHYDROGENASE; SHH PROTEIN, HUMAN; SMALL INTERFERING RNA; SOX2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX;

APOPTOSIS; ARTICLE; CANCER CELL; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; GENE SILENCING; HUMAN; HUMAN CELL; MCF 7 CELL LINE; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TUMOR INVASION; TUMOR RECURRENCE; ANTAGONISTS AND INHIBITORS; BREAST TUMOR; CANCER STEM CELL; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ERINACEIDAE;

BREAST NEOPLASMS; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; ISOENZYMES; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; POLYCOMB REPRESSIVE COMPLEX 1; RECEPTORS, CELL SURFACE; RECEPTORS, ESTROGEN; RETINAL DEHYDROGENASE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SOXB1 TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS;

EID: 84902545803     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-137     Document Type: Article

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