Gene silencing of BAG-1 modulates apoptotic genes and sensitizes lung cancer cell lines to cisplatin-induced apoptosis

Cancer Biology and Therapy

Volumn 9, Issue 10, 2010, Pages 832-840

  Liu, Hongyu ^a   Liang, Yonggang ^b   Li, Ying ^a   Li, Yongwen ^a   Wang, Jing ^a   Wu, Heng ^a   Wang, Yuli ^a   Tang, Shou Ching ^a,c   Chen, Jun ^a   Zhou, Qinghua ^a,b  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Apoptosis; BAG 1; Lung cancer; siRNA

Indexed keywords

BAG 1 PROTEIN; CISPLATIN; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; BCL2 ASSOCIATED ATHANOGENE 1 PROTEIN; BCL2-ASSOCIATED ATHANOGENE 1 PROTEIN; DNA BINDING PROTEIN; LYN PROTEIN-TYROSINE KINASE; PROTEIN KINASE LYN; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CANCER CELL; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CANCER; RNA INTERFERENCE; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE; BAG1 GENE; BTG2 GENE; CANCER CELL CULTURE; CARD8 GENE; CASP7 GENE; CCNE2 GENE; CDC27 GENE; CDKN2C GENE; CLDN1 GENE; COL5A1 GENE; CUL2 GENE; EGFR GENE; EIF1AX GENE; EIF4E GENE; EPAS1 GENE; EV15 GENE; FGF2 GENE; FN1 GENE; FZD1 GENE; GADD45BETA GENE; GENE; HDAC4 GENE; HRAS GENE; HSPA1A GENE; IGF1R GENE; IGFBP1 GENE; IL1ALPHA GENE; IL8 GENE; ITGBETA1 GENE; KAT2B GENE; LUNG ADENOCARCINOMA; MAP3K2 GENE; MAP3K7 GENE; MAPK1 GENE; MICROARRAY ANALYSIS; MKI67 GENE; MMP1 GENE; MTR GENE; NDC80 GENE; NFKAPPAB2 GENE; NR4A1 GENE; NRP1 GENE; NRP2 GENE; ONCOGENE; ONCOGENE H RAS; PAK2 GENE; PDCD4 GENE; PDCD6IP GENE; RPS6KA5 GENE; SCARB2 GENE; SDC4 GENE; SERPINE1 GENE; TGF ALPHA GENE; TGFBETA2 GENE; TNFRSF10D GENE; TUSC2 GENE; UPREGULATION; VEGFALPHA GENE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CISPLATIN; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HUMANS; LUNG NEOPLASMS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSCRIPTION FACTORS;

EID: 77953709812     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.9.10.11589     Document Type: Article

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