Proteomic and biochemical studies of lysine malonylation suggest its malonic aciduriaassociated regulatory role in mitochondrial function and fatty acid oxidation

Molecular and Cellular Proteomics

Volumn 14, Issue 11, 2015, Pages 3056-3071

  Colak, Gozde ^a   Pougovkina, Olga ^b   Dai, Lunzhi ^a   Tan, Minjia ^c   Te Brinke, Heleen ^b   Huang, He ^a   Cheng, Zhongyi ^d   Park, Jeongsoon ^e   Wan, Xuelian ^c   Liu, Xiaojing ^f   Yue, Wyatt W ^g   Wanders, Ronald J A ^b   Locasale, Jason W ^f   Lombard, David B ^e   De Boer, Vincent C J ^b   Zhao, Yingming ^a,c,g  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^d PTM Biolabs   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f Cornell University ^*  (United States)

^g UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; FATTY ACID SYNTHASE; LONG CHAIN 3 HYDROXYACYL COENZYME A DEHYDROGENASE; LYSINE; MALONYL COENZYME A; SIRTUIN 5; CARBOXYLYASE; FATTY ACID; MALONIC ACID; MALONIC ACID DERIVATIVE; MALONYL-COA DECARBOXYLASE; METHYLMALONIC ACID; SIRT5 PROTEIN, MOUSE; SIRTUIN;

ACYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; FATTY ACID OXIDATION; FIBROBLAST; HEPATOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INBORN ERROR OF METABOLISM; LIPOGENESIS; LYSINE MALONYLATION; MALE; MALONIC ACIDURIA; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STOICHIOMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; CELL LINE; CYTOLOGY; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM; MOLECULAR MODEL; PATHOLOGY;

ANIMALS; CARBOXY-LYASES; CELL LINE; FATTY ACIDS; FIBROBLASTS; HUMANS; LIVER; LYSINE; MALE; MALONATES; MALONYL COENZYME A; METABOLISM, INBORN ERRORS; METHYLMALONIC ACID; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MODELS, MOLECULAR; OXIDATION-REDUCTION; SIRTUINS;

EID: 84946018029     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M115.048850     Document Type: Article

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