Structural basis for substrate fatty acyl chain specificity: Crystal structure of human very-long-chain acyl-CoA dehydrogenase

Journal of Biological Chemistry

Volumn 283, Issue 14, 2008, Pages 9435-9443

  McAndrew, Ryan P ^a   Wang, Yudong ^b   Mohsen, Al Walid ^b   He, Miao ^b   Vockley, Jerry ^b   Kim, Jung Ja P ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; ENZYMES; LIGANDS; PLANTS (BOTANY); PORT TERMINALS; SUBSTRATES;

ACYL CHAIN LENGTHS; ACYL MOIETIES; BINDING CHANNELS; BOUND LIGANDS; C TERMINUSES; CATALYTIC BASE; FATTY ACYL CHAINS; GAIN INSIGHTS; HELICAL BUNDLES; HELICAL DOMAINS; HIGH MOBILITIES; HOMODIMER; HOMOTETRAMERS; MITOCHONDRIAL MEMBRANES; PARTIAL HYDROLYSIS; STRUCTURAL BASES; SUBSTRATE BINDINGS; TERMINAL DOMAINS; THIO ESTERS;

CRYSTAL STRUCTURE;

ACYL COENZYME A DEHYDROGENASE; CARBON; FLAVINE ADENINE NUCLEOTIDE; GLUTAMIC ACID; GLYCINE; HOMODIMER; PROTEIN N MYRISTOYLTRANSFERASE; ACYL COENZYME A; FATTY ACID; LIGAND; LONG CHAIN ACYL COENZYME A DEHYDROGENASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; FATTY ACID OXIDATION; MITOCHONDRIAL MEMBRANE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; CHEMISTRY; DIMERIZATION; DISORDERS OF LIPID AND LIPOPROTEIN METABOLISM; ENZYMOLOGY; GENETICS; GENOTYPE; HUMAN; LIPID METABOLISM; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ACYL COENZYME A; ACYL-COA DEHYDROGENASE, LONG-CHAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; FATTY ACIDS; GENOTYPE; HUMANS; LIGANDS; LIPID METABOLISM; LIPID METABOLISM, INBORN ERRORS; MITOCHONDRIA; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 44049088356     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M709135200     Document Type: Article

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