MAPK inhibitors modulate Smad2/3/4 complex cyto-nuclear translocation in myofibroblasts via Imp7/8 mediation

Molecular and Cellular Biochemistry

Volumn 406, Issue 1-2, 2015, Pages 255-262

  Jiang, Yufeng ^a   Wu, Chao ^a   Boye, Alex ^a   Wu, Jiajun ^a   Wang, Jiyu ^a   Yang, Xiaochuan ^a   Yang, Yan ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Imp7 8; MAPK inhibitors; Myofibroblasts; PAI 1; Smads; TGF 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; IMPORTIN7; IMPORTIN8; KARYOPHERIN; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; FLAVONOID; KARYOPHERIN ALPHA; KARYOPHERIN BETA; KPNA6 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELL MIGRATION; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE TRANSLOCATION; MALE; MYOFIBROBLAST; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ACTIVE TRANSPORT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; ANIMALS; ANTHRACENES; BETA KARYOPHERINS; CELLS, CULTURED; FLAVONOIDS; GENE EXPRESSION; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; MYOFIBROBLASTS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS, SPRAGUE-DAWLEY; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84945901879     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2443-x     Document Type: Article

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