MAPK inhibitors differently modulate TGF-β/Smad signaling in HepG2 cells

Tumor Biology

Volumn 36, Issue 5, 2015, Pages 3643-3651

  Boye, A ^a   Kan, H ^a   Wu, C ^a   Jiang, Y ^a   Yang, X ^a   He, S ^a   Yang, Y ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; MAPK specific inhibitors; Smad; TGF 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; JANUS KINASE 1; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; DIETHYLNITROSAMINE; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERPINE1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INVASION; CELL INVASION ASSAY; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DRUG POTENCY; ENZYME PHOSPHORYLATION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; LIVER CELL CARCINOMA; MALE; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; TUMOR INVASION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARCINOGENESIS; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; PATHOLOGY;

ANIMALS; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DIETHYLNITROSAMINE; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEOPLASM INVASIVENESS; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84929956487     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-3002-x     Document Type: Article

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