Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

Oncotarget

Volumn 6, Issue 31, 2015, Pages 30453-30471

  Lamb, Rebecca ^a,b   Bonuccelli, Gloria ^a,b   Ozsvári, Béla ^a,b   Peiris Pagès, Maria ^a,b   Fiorillo, Marco ^a,b,c   Smith, Duncan L ^d   Bevilacqua, Generoso ^e,f   Mazzanti, Chiara Maria ^e   McDonnell, Liam A ^e   Naccarato, Antonio Giuseppe ^f   Chiu, Maybo ^a,b   Wynne, Luke ^a,b   Martinez Outschoorn, Ubaldo E ^g   Sotgia, Federica ^a,b   Lisanti, Michael P ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF CALABRIA   (Italy)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e Pisa Science Foundation   (Italy)

^f UNIVERSITY HOSPITAL OF PISA   (Italy)

^g THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

FGF; Mitochondria; MitoTracker; MMTV; WNT

Indexed keywords

FIBROBLAST GROWTH FACTOR 3; GLYCOLYTIC ENZYME; MITOCHONDRIAL PROTEIN; WNT1 PROTEIN; CONDITIONED MEDIUM; FGF3 PROTEIN, HUMAN; TUMOR MARKER; WNT1 PROTEIN, HUMAN;

ARTICLE; AVIAN LEUKOSIS VIRUS; BIOGENESIS; BIOINFORMATICS; BREAST CANCER; BREAST CANCER CELL LINE; BREAST CARCINOGENESIS; CANCER STEM CELL; CELL ACTIVITY; CELL PROLIFERATION; CELLULAR PARAMETERS; CONTROLLED STUDY; CULTURE MEDIUM; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE INSERTION; GENETIC TRANSFECTION; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR SIGNALING; MCF 7 CELL LINE; MITOCHONDRIAL MASS; MOUSE MAMMARY TUMOR VIRUS; NONHUMAN; PERSONALIZED MEDICINE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEOMICS; T47D CELL LINE; UPREGULATION; VIRUS CARCINOGENESIS; WNT SIGNALING PATHWAY; BIOLOGICAL MODEL; BIOSYNTHESIS; BREAST TUMOR; CONDITIONED MEDIUM; CYTOLOGY; FEMALE; GENETICS; MCF-7 CELL LINE; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MULTICELLULAR SPHEROID; PATHOGENICITY; PATHOLOGY; PHARMACOLOGY; PHYSIOLOGY; SECRETION (PROCESS); TUMOR CELL CULTURE;

BIOMARKERS, TUMOR; BREAST NEOPLASMS; CULTURE MEDIA, CONDITIONED; FEMALE; FIBROBLAST GROWTH FACTOR 3; HUMANS; MAMMARY TUMOR VIRUS, MOUSE; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MODELS, BIOLOGICAL; NEOPLASTIC STEM CELLS; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED; WNT SIGNALING PATHWAY; WNT1 PROTEIN;

EID: 84945575145     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.5852     Document Type: Article

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