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Volumn 5, Issue 9, 2006, Pages 1059-1064

Cross-talk of WNT and FGF signaling pathways at GSK3β to regulate β-catenin and SNAIL signaling cascades

Author keywords

Epithelial mesenchymal transition; FGF; GSK3 ; Oncogenomics; Pharmacogenomics; SNAIL; WNT; catenin

Indexed keywords

AROMATASE; BETA CATENIN; CYP19A1; FIBROBLAST GROWTH FACTOR 18; FIBROBLAST GROWTH FACTOR 20; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; INITIATION FACTOR 3; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MYC PROTEIN; NOTCH4 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN GRB2; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN WNT10B; SERINE; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; UVOMORULIN; WNT PROTEIN; WNT3A PROTEIN;

EID: 33751073938     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.9.3151     Document Type: Review
Times cited : (234)

References (94)
  • 1
    • 0027395703 scopus 로고
    • Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and Hst/Fgf-4
    • Shackleford GM, MacArthur CA, Kwan HC, Varmus HE. Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and Hst/Fgf-4. Proc Natl Acad Sci USA 1993; 90:740-4.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 740-744
    • Shackleford, G.M.1    MacArthur, C.A.2    Kwan, H.C.3    Varmus, H.E.4
  • 2
    • 0028911173 scopus 로고
    • Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice
    • Lee FS, Lane TF, Kuo A, Shackleford GM, Leder P. Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice. Proc Natl Acad Sci USA 1995; 92:2268-72.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2268-2272
    • Lee, F.S.1    Lane, T.F.2    Kuo, A.3    Shackleford, G.M.4    Leder, P.5
  • 3
    • 0028932077 scopus 로고
    • Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis
    • MacArthur CA, Shankar DB, Shackleford GM. Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis. J Virol 1995; 69:2501-7.
    • (1995) J Virol , vol.69 , pp. 2501-2507
    • MacArthur, C.A.1    Shankar, D.B.2    Shackleford, G.M.3
  • 4
    • 0242381919 scopus 로고    scopus 로고
    • WNT and FGF gene clusters
    • Katoh M. WNT and FGF gene clusters. Int J Oncol 2002; 21:1269-73.
    • (2002) Int J Oncol , vol.21 , pp. 1269-1273
    • Katoh, M.1
  • 5
    • 0030776762 scopus 로고    scopus 로고
    • A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1
    • McWhirter JR, Goulding M, Weiner JA, Chun J, Murre C. A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. Development 1997; 124:3221-32.
    • (1997) Development , vol.124 , pp. 3221-3232
    • McWhirter, J.R.1    Goulding, M.2    Weiner, J.A.3    Chun, J.4    Murre, C.5
  • 6
    • 0033613097 scopus 로고    scopus 로고
    • Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia
    • McWhirter JR, Neuteboom ST, Wancewicz EV, Monia BP, Downing JR, Murre C. Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia. Proc Natl Acad Sci USA 1999; 96:11464-9.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11464-11469
    • McWhirter, J.R.1    Neuteboom, S.T.2    Wancewicz, E.V.3    Monia, B.P.4    Downing, J.R.5    Murre, C.6
  • 8
    • 0141919600 scopus 로고    scopus 로고
    • Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the β-catenin/T-cell factor complex
    • Shimokawa T, Furukawa Y, Sakai M, Li M, Miwa N, Lin YM, Nakamura Y. Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the β-catenin/T-cell factor complex. Cancer Res 2003; 63:6116-20.
    • (2003) Cancer Res , vol.63 , pp. 6116-6120
    • Shimokawa, T.1    Furukawa, Y.2    Sakai, M.3    Li, M.4    Miwa, N.5    Lin, Y.M.6    Nakamura, Y.7
  • 9
    • 13244299109 scopus 로고    scopus 로고
    • FGF20 and DKK1 are transcriptional target of β-catenin and FGF20 is implicated in cancer and development
    • Chamorro MN, Schwartz DR, Vonica A, Brivanlou AH, Cho KR, Varmus HE. FGF20 and DKK1 are transcriptional target of β-catenin and FGF20 is implicated in cancer and development. EMBO J 2005; 24:73-84.
    • (2005) EMBO J , vol.24 , pp. 73-84
    • Chamorro, M.N.1    Schwartz, D.R.2    Vonica, A.3    Brivanlou, A.H.4    Cho, K.R.5    Varmus, H.E.6
  • 10
    • 24644516785 scopus 로고    scopus 로고
    • Comparative genomics on FGF20 orthologs
    • Katoh M, Katoh M. Comparative genomics on FGF20 orthologs. Oncol Rep 2005; 14:287-90.
    • (2005) Oncol Rep , vol.14 , pp. 287-290
    • Katoh, M.1    Katoh, M.2
  • 11
    • 25644448919 scopus 로고    scopus 로고
    • Comparative genomics on FGF8, FGF17, and FGF18 orthologs
    • Katoh M, Katoh M. Comparative genomics on FGF8, FGF17, and FGF18 orthologs. Int J Mol Med 2005; 16:493-6.
    • (2005) Int J Mol Med , vol.16 , pp. 493-496
    • Katoh, M.1    Katoh, M.2
  • 12
    • 33644635985 scopus 로고    scopus 로고
    • Comparative genomics on FGF16 orthologs
    • Katoh Y, Katoh M. Comparative genomics on FGF16 orthologs. Int J Mol Med 2005; 16:959-63.
    • (2005) Int J Mol Med , vol.16 , pp. 959-963
    • Katoh, Y.1    Katoh, M.2
  • 13
    • 0242690094 scopus 로고    scopus 로고
    • Lineage choice and differentiation in mouse embryos and embryonic stem cells
    • Loebel DA, Watson CM, De Young RA, Tam PP. Lineage choice and differentiation in mouse embryos and embryonic stem cells. Dev Biol 2003; 264:1-14.
    • (2003) Dev Biol , vol.264 , pp. 1-14
    • Loebel, D.A.1    Watson, C.M.2    De Young, R.A.3    Tam, P.P.4
  • 14
    • 0031423765 scopus 로고    scopus 로고
    • Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus
    • McGrew LL, Hoppler S, Moon RT. Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus. Mech Dev 1997; 69:105-14.
    • (1997) Mech Dev , vol.69 , pp. 105-114
    • McGrew, L.L.1    Hoppler, S.2    Moon, R.T.3
  • 15
    • 0029100040 scopus 로고
    • Vertebrate limb development
    • Tickle C. Vertebrate limb development. Curr Opin Genet Dev 1995; 5:478-84.
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 478-484
    • Tickle, C.1
  • 17
    • 0037081282 scopus 로고    scopus 로고
    • Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest induction
    • Villanueva S, Glavic A, Ruiz P, Mayor R. Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest induction. Dev Biol 2002; 241:289-301.
    • (2002) Dev Biol , vol.241 , pp. 289-301
    • Villanueva, S.1    Glavic, A.2    Ruiz, P.3    Mayor, R.4
  • 19
    • 0035514407 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human WNT3
    • Katoh M. Molecular cloning and characterization of human WNT3. Int J Oncol 2001; 19:977-82.
    • (2001) Int J Oncol , vol.19 , pp. 977-982
    • Katoh, M.1
  • 20
    • 0034810770 scopus 로고    scopus 로고
    • Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region
    • Saitoh T, Hirai M, Katoh M. Molecular cloning and characterization of WNT3A and WNT14 clustered in human chromosome 1q42 region. Biochem Biophys Res Commun 2001; 284:1168-75.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 1168-1175
    • Saitoh, T.1    Hirai, M.2    Katoh, M.3
  • 21
    • 0035513845 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human WNT14B, a novel member of the WNT gene family
    • Kirikoshi H, Sekihara H, Katoh M. Molecular cloning and characterization of human WNT14B, a novel member of the WNT gene family. Int J Oncol 2001; 19:947-52.
    • (2001) Int J Oncol , vol.19 , pp. 947-952
    • Kirikoshi, H.1    Sekihara, H.2    Katoh, M.3
  • 22
    • 0036618209 scopus 로고    scopus 로고
    • WNT3-WNT14B and WNT3A-WNT14 gene clusters
    • Katoh M. WNT3-WNT14B and WNT3A-WNT14 gene clusters. Int J Mol Med 2002; 9:579-84.
    • (2002) Int J Mol Med , vol.9 , pp. 579-584
    • Katoh, M.1
  • 23
    • 0034810488 scopus 로고    scopus 로고
    • WNT10A and WNT6, clustered in human chromosome 2q35 region with head to tail manner, are strongly coexpressed in SW480 cells
    • Kirikoshi H, Sekihara H, Katoh M. WNT10A and WNT6, clustered in human chromosome 2q35 region with head to tail manner, are strongly coexpressed in SW480 cells. Biochem Biophys Res Commun 2001; 283:798-805.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 798-805
    • Kirikoshi, H.1    Sekihara, H.2    Katoh, M.3
  • 24
    • 1542494467 scopus 로고    scopus 로고
    • Evolutionary conservation of CCND1-ORAOV1-FGF19- FGF4 locus from zebrafish to human
    • Katoh M, Katoh M. Evolutionary conservation of CCND1-ORAOV1-FGF19- FGF4 locus from zebrafish to human. Int J Mol Med 2003; 12:45-50.
    • (2003) Int J Mol Med , vol.12 , pp. 45-50
    • Katoh, M.1    Katoh, M.2
  • 25
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N, Ornitz DM. Evolution of the Fgf and Fgfr gene families. Trends Genet 2004; 20:563-9.
    • (2004) Trends Genet , vol.20 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 26
    • 0041976019 scopus 로고    scopus 로고
    • The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation
    • Fischer S, Draper BW, Neumann CJ. The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation. Development 2003; 130:3515-24.
    • (2003) Development , vol.130 , pp. 3515-3524
    • Fischer, S.1    Draper, B.W.2    Neumann, C.J.3
  • 27
    • 33644669780 scopus 로고    scopus 로고
    • Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25
    • Katoh Y, Katoh M. Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25. Int J Mol Med 2005; 16:767-70.
    • (2005) Int J Mol Med , vol.16 , pp. 767-770
    • Katoh, Y.1    Katoh, M.2
  • 28
    • 33751113439 scopus 로고    scopus 로고
    • FGF signaling network in the gastrointestinal tract
    • Katoh M, Katoh M. FGF signaling network in the gastrointestinal tract. Int J Oncol 2006; 29:163-8.
    • (2006) Int J Oncol , vol.29 , pp. 163-168
    • Katoh, M.1    Katoh, M.2
  • 31
    • 0032501156 scopus 로고    scopus 로고
    • Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2, and Frizzled-7
    • Sagara N, Toda G, Hirai M, Terada M, Katoh M. Molecular cloning, differential expression, and chromosomal localization of human Frizzled-1, Frizzled-2, and Frizzled-7. Biochem Biophys Res Commun 1998; 252:117-22.
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 117-122
    • Sagara, N.1    Toda, G.2    Hirai, M.3    Terada, M.4    Katoh, M.5
  • 35
    • 0035491631 scopus 로고    scopus 로고
    • Expression profiles of 10 members of Frizzled gene family in human gastric cancer
    • Kirikoshi H, Sekihara H, Katoh M. Expression profiles of 10 members of Frizzled gene family in human gastric cancer. Int J Oncol 2001; 19:767-71.
    • (2001) Int J Oncol , vol.19 , pp. 767-771
    • Kirikoshi, H.1    Sekihara, H.2    Katoh, M.3
  • 36
    • 0344413477 scopus 로고    scopus 로고
    • Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
    • Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol Cell 2003; 12:1251-60.
    • (2003) Mol Cell , vol.12 , pp. 1251-1260
    • Wong, H.C.1    Bourdelas, A.2    Krauss, A.3    Lee, H.J.4    Shao, Y.5    Wu, D.6    Mlodzik, M.7    Shi, D.L.8    Zheng, J.9
  • 37
  • 38
    • 0037343952 scopus 로고    scopus 로고
    • Wg/Wnt signal can be transmitted through arrow/LRP5, 6 and Axin independently of Zw3/Gsk3β activity
    • Tolwinski NS, Wehrli M, Rives A, Erdeniz N, DiNardo S, Wieschaus E. Wg/Wnt signal can be transmitted through arrow/LRP5, 6 and Axin independently of Zw3/Gsk3β activity. Dev Cell 2003; 4:407-18.
    • (2003) Dev Cell , vol.4 , pp. 407-418
    • Tolwinski, N.S.1    Wehrli, M.2    Rives, A.3    Erdeniz, N.4    DiNardo, S.5    Wieschaus, E.6
  • 39
    • 0242704649 scopus 로고    scopus 로고
    • Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
    • Schweizer L, Varmus H. Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors. BMC Cell Biol 2003; 4:4.
    • (2003) BMC Cell Biol , vol.4 , pp. 4
    • Schweizer, L.1    Varmus, H.2
  • 40
    • 24644472384 scopus 로고    scopus 로고
    • Comparative genomics on DKK1 orthologs
    • Katoh Y, Katoh M. Comparative genomics on DKK1 orthologs. Int J Oncol 2005; 27:275-9.
    • (2005) Int J Oncol , vol.27 , pp. 275-279
    • Katoh, Y.1    Katoh, M.2
  • 42
    • 0033119801 scopus 로고    scopus 로고
    • β-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F. β-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999; 398:422-6.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 44
    • 0037023584 scopus 로고    scopus 로고
    • Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex
    • Kramps T, Peter O, Brunner E, Nellen D, Froesch B, Chatterjee S, Murone M, Zullig S, Basler K. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex. Cell 2002; 109:47-60.
    • (2002) Cell , vol.109 , pp. 47-60
    • Kramps, T.1    Peter, O.2    Brunner, E.3    Nellen, D.4    Froesch, B.5    Chatterjee, S.6    Murone, M.7    Zullig, S.8    Basler, K.9
  • 45
    • 2842563838 scopus 로고    scopus 로고
    • Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico
    • Katoh M, Katoh M. Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico. Int J Mol Med 2003; 12:643-9.
    • (2003) Int J Mol Med , vol.12 , pp. 643-649
    • Katoh, M.1    Katoh, M.2
  • 46
    • 1842430786 scopus 로고    scopus 로고
    • A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes
    • Thompson BJ. A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes. Curr Biol 2004; 14:458-66.
    • (2004) Curr Biol , vol.14 , pp. 458-466
    • Thompson, B.J.1
  • 47
    • 3242706980 scopus 로고    scopus 로고
    • Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional coactivator function
    • Townsley FM, Cliffe A, Bienz M. Pygopus and Legless target Armadillo/β-catenin to the nucleus to enable its transcriptional coactivator function. Nat Cell Biol 2004; 6:626-33.
    • (2004) Nat Cell Biol , vol.6 , pp. 626-633
    • Townsley, F.M.1    Cliffe, A.2    Bienz, M.3
  • 48
    • 20344403092 scopus 로고    scopus 로고
    • Identification and characterization of rat Bcl9l gene in silico
    • Katoh Y, Katoh M. Identification and characterization of rat Bcl9l gene in silico. Int J Oncol 2005; 26:835-40.
    • (2005) Int J Oncol , vol.26 , pp. 835-840
    • Katoh, Y.1    Katoh, M.2
  • 49
    • 21844437361 scopus 로고    scopus 로고
    • Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin
    • Hoffmans R, Stadeli R, Basler K. Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin. Curr Biol 2005; 15:1207-11.
    • (2005) Curr Biol , vol.15 , pp. 1207-1211
    • Hoffmans, R.1    Stadeli, R.2    Basler, K.3
  • 50
    • 26944436274 scopus 로고    scopus 로고
    • Dissecting nuclear Wingless signalling: Recruitment of the transcriptional coactivator Pygopus by a chain of adaptor proteins
    • Stadeli R, Basler K. Dissecting nuclear Wingless signalling: Recruitment of the transcriptional coactivator Pygopus by a chain of adaptor proteins. Mech Dev 2005; 122:1171-82.
    • (2005) Mech Dev , vol.122 , pp. 1171-1182
    • Stadeli, R.1    Basler, K.2
  • 51
    • 33644878286 scopus 로고    scopus 로고
    • WNT2B: Comparative integromics and clinical application
    • Katoh M. WNT2B: Comparative integromics and clinical application. Int J Mol Med 2005; 16:1103-8.
    • (2005) Int J Mol Med , vol.16 , pp. 1103-1108
    • Katoh, M.1
  • 52
    • 19644383031 scopus 로고    scopus 로고
    • Identification and characterization of rat Ror1 and Ror2 genes in silico
    • Katoh M, Katoh M. Identification and characterization of rat Ror1 and Ror2 genes in silico. Int J Mol Med 2005; 15:533-8.
    • (2005) Int J Mol Med , vol.15 , pp. 533-538
    • Katoh, M.1    Katoh, M.2
  • 53
    • 27744528481 scopus 로고    scopus 로고
    • Comparative genomics on ROR1 and ROR2 orthologs
    • Katoh M, Katoh M. Comparative genomics on ROR1 and ROR2 orthologs. Oncol Rep 2005; 14:1381-4.
    • (2005) Oncol Rep , vol.14 , pp. 1381-1384
    • Katoh, M.1    Katoh, M.2
  • 54
    • 33644698339 scopus 로고    scopus 로고
    • WNT/PCP signaling pathway and human cancer
    • Katoh M. WNT/PCP signaling pathway and human cancer. Oncol Rep 2005; 14:1583-8.
    • (2005) Oncol Rep , vol.14 , pp. 1583-1588
    • Katoh, M.1
  • 55
    • 0042033824 scopus 로고    scopus 로고
    • Regulation of WNT signaling molecules by retinoic acid during neuronal differentiation in NT2 cells: Threshold model of WNT action
    • Katoh M. Regulation of WNT signaling molecules by retinoic acid during neuronal differentiation in NT2 cells: Threshold model of WNT action. Int J Mol Med 2002; 10:683-7.
    • (2002) Int J Mol Med , vol.10 , pp. 683-687
    • Katoh, M.1
  • 57
    • 0030941498 scopus 로고    scopus 로고
    • A member of the Frizzled protein family mediating axis induction by Wnt-5A
    • He X, Saint-Jeannet JP, Wang Y, Nathans J, Dawid I, Varmus H. A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 1997; 275:1652-4.
    • (1997) Science , vol.275 , pp. 1652-1654
    • He, X.1    Saint-Jeannet, J.P.2    Wang, Y.3    Nathans, J.4    Dawid, I.5    Varmus, H.6
  • 58
    • 33646007215 scopus 로고    scopus 로고
    • Xenopus frizzled-4S, a splicing variant of Xfz4, is a context-dependent activator and inhibitor of Wnt/β-catenin signaling
    • Swain RK, Katoh M, Medina A, Steinbeisser H. Xenopus frizzled-4S, a splicing variant of Xfz4, is a context-dependent activator and inhibitor of Wnt/β-catenin signaling. Cell Commun Signal 2005; 3:12.
    • (2005) Cell Commun Signal , vol.3 , pp. 12
    • Swain, R.K.1    Katoh, M.2    Medina, A.3    Steinbeisser, H.4
  • 59
    • 0024375271 scopus 로고
    • Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor
    • Lee PL, Johnson DE, Cousens LS, Fried VA, Williams LT. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 1989; 245:57-60.
    • (1989) Science , vol.245 , pp. 57-60
    • Lee, P.L.1    Johnson, D.E.2    Cousens, L.S.3    Fried, V.A.4    Williams, L.T.5
  • 64
    • 0043130471 scopus 로고    scopus 로고
    • FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26
    • Katoh M, Katoh M. FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26. Int J Oncol 2003; 22:1155-9.
    • (2003) Int J Oncol , vol.22 , pp. 1155-1159
    • Katoh, M.1    Katoh, M.2
  • 65
    • 0642378291 scopus 로고    scopus 로고
    • Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26
    • Katoh M, Katoh M. Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26. Int J Mol Med 2003; 11:579-83.
    • (2003) Int J Mol Med , vol.11 , pp. 579-583
    • Katoh, M.1    Katoh, M.2
  • 68
  • 69
    • 0033974109 scopus 로고    scopus 로고
    • FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors
    • Ong SH, Guy GR, Hadari YR, Laks S, Gotoh N, Schlessinger J, Lax I. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. Mol Cell Biol 2000; 20:979-89.
    • (2000) Mol Cell Biol , vol.20 , pp. 979-989
    • Ong, S.H.1    Guy, G.R.2    Hadari, Y.R.3    Laks, S.4    Gotoh, N.5    Schlessinger, J.6    Lax, I.7
  • 70
    • 0035933094 scopus 로고    scopus 로고
    • Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins
    • Ong SH, Hadari YR, Gotoh N, Guy GR, Schlessinger J, Lax I. Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins. Proc Natl Acad Sci USA 2001; 98:6074-9.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6074-6079
    • Ong, S.H.1    Hadari, Y.R.2    Gotoh, N.3    Guy, G.R.4    Schlessinger, J.5    Lax, I.6
  • 71
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296:1655-7.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 72
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
    • Luo J, Manning BD, Cantley LC. Targeting the PI3K-Akt pathway in human cancer: Rationale and promise. Cancer Cell 2003; 4:257-62.
    • (2003) Cancer Cell , vol.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3
  • 73
    • 0038003956 scopus 로고    scopus 로고
    • Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
    • Burgering BM, Medema RH. Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty. J Leukoc Biol 2003; 73:689-701.
    • (2003) J Leukoc Biol , vol.73 , pp. 689-701
    • Burgering, B.M.1    Medema, R.H.2
  • 74
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame S, Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem J 2001; 359:1-16.
    • (2001) Biochem J , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 75
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial - Mesenchymal transition
    • Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M, Hung MC. Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial - mesenchymal transition. Nat Cell Biol 2004; 6:931-40.
    • (2004) Nat Cell Biol , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 77
    • 33644817029 scopus 로고    scopus 로고
    • Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs
    • Katoh M, Katoh M. Comparative genomics on SNAI1, SNAI2, and SNAI3 orthologs. Oncol Rep 2005; 14:1083-6.
    • (2005) Oncol Rep , vol.14 , pp. 1083-1086
    • Katoh, M.1    Katoh, M.2
  • 78
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol 2006; 7:131-42.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 79
    • 33644829069 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in gastric cancer
    • Katoh M. Epithelial-mesenchymal transition in gastric cancer. Int J Oncol 2005; 27:1677-83.
    • (2005) Int J Oncol , vol.27 , pp. 1677-1683
    • Katoh, M.1
  • 80
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990; 61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 86
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006; 6:107-16.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 87
    • 21644467144 scopus 로고    scopus 로고
    • Pharmacogenomics on gastric cancer
    • Katoh M, Katoh M. Pharmacogenomics on gastric cancer. Cancer Biol Ther 2004; 3:566-7.
    • (2004) Cancer Biol Ther , vol.3 , pp. 566-567
    • Katoh, M.1    Katoh, M.2
  • 88
    • 27744583597 scopus 로고    scopus 로고
    • Hedgehog signaling pathway and gastric cancer
    • Katoh Y, Katoh M. Hedgehog signaling pathway and gastric cancer. Cancer Biol Ther 2005; 4:1045-9.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1045-1049
    • Katoh, Y.1    Katoh, M.2
  • 89
    • 1642323740 scopus 로고    scopus 로고
    • Protein kinase inhibitors: Insights into drug design from structure
    • Noble ME, Endicott JA, Johnson LN. Protein kinase inhibitors: Insights into drug design from structure. Science 2004; 303:1800-5.
    • (2004) Science , vol.303 , pp. 1800-1805
    • Noble, M.E.1    Endicott, J.A.2    Johnson, L.N.3
  • 90
    • 12944284651 scopus 로고    scopus 로고
    • Dual inhibition of RET and FGFR4 restrains medullary thyroid cancer cell growth
    • Ezzat S, Huang P, Dackiw A, Asa SL. Dual inhibition of RET and FGFR4 restrains medullary thyroid cancer cell growth. Clin Cancer Res 2005; 11:1336-41.
    • (2005) Clin Cancer Res , vol.11 , pp. 1336-1341
    • Ezzat, S.1    Huang, P.2    Dackiw, A.3    Asa, S.L.4


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