Dihydromyricetin improves skeletal muscle insulin sensitivity by inducing autophagy via the AMPK-PGC-1α-Sirt3 signaling pathway

Endocrine

Volumn 50, Issue 2, 2015, Pages 378-389

  Shi, Linying ^a   Zhang, Ting ^a   Zhou, Yong ^a   Zeng, Xianglong ^a   Ran, Li ^a   Zhang, Qianyong ^a   Zhu, Jundong ^a   Mi, Mantian ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Dihydromyricetin; Sirt3; Skeletal muscle insulin sensitivity; Type 2 diabetes

Indexed keywords

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; BAFILOMYCIN A1; DIHYDROMYRICETIN; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MYRICETIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN; SEQUESTOSOME 1; SIRTUIN 3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; FLAVONOL DERIVATIVE; PPARGC1A PROTEIN, MOUSE; SIRT3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GLUCOSE TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; INTRACELLULAR SIGNALING; LIGHT CHAIN; MALE; MOUSE; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SKELETAL MUSCLE; 129 MOUSE; ANIMAL; DRUG EFFECTS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; FLAVONOLS; INSULIN RESISTANCE; MALE; MICE; MICE, 129 STRAIN; MUSCLE, SKELETAL; SIGNAL TRANSDUCTION; SIRTUIN 3; TRANSCRIPTION FACTORS;

EID: 84945494393     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-015-0599-5     Document Type: Article

References (31)

1. Y.S. Zhang, Z.X. Ning, S.Z. Yang, H. Wu, Yao Xue Xue Bao 38(4), 241–244 (2003)
2. J.M. Harnly, R.F. Doherty, G.R. Beecher, J.M. Holden, D.B. Haytowitz, S. Bhagwat, S. Gebhardt, J. Agric. Food Chem. 54(26), 9966–9977 (2006)
3. P. Pu, D.M. Gao, S. Mohamed, J. Chen, J. Zhang, X.Y. Zhou, N.J. Zhou, J. Xie, H. Jiang, Arch. Biochem. Biophys. 518(1), 61–70 (2012)
4. X. Dai, Y. Ding, Z. Zhang, X. Cai, L. Bao, Y. Li, Biol. Pharm. Bull. 36(5), 788–795 (2013)
5. Y. Kondo, S. Kondo, Autophagy 2(2), 85–90 (2006)
6. H.S. Jung, K.W. Chung, K.J. Won, J. Kim, M. Komatsu, K. Tanaka, Y.H. Nguyen, T.M. Kang, K.H. Yoon, J.W. Kim, Y.T. Jeong, M.S. Han, M.K. Lee, K.W. Kim, J. Shin, M.S. Lee, Cell Metab. 8(4), 318–324 (2008)
7. C. He, M.C. Bassik, V. Moresi, K. Sun, Y. Wei, Z. Zou, Z. An, J. Loh, J. Fisher, Q. Sun, S. Korsmeyer, M. Packer, H.I. May, J.A. Hill, H.W. Virgin, C. Gilpin, G. Xiao, R. Bassel-Duby, P.E. Scherer, B. Levine, Nature 481(7382), 511–515 (2012)
8. Y. Zhou, X. Liang, H. Chang, F. Shu, Y. Wu, T. Zhang, Y. Fu, Q. Zhang, J.D. Zhu, M. Mi, Cancer Sci. 105(10), 1279–1287 (2014)
9. E. Jing, B. Emanuelli, M.D. Hirschey, J. Boucher, K.Y. Lee, D. Lombard, E.M. Verdin, C.R. Kahn, Proc Natl Acad Sci USA 108(35), 14608–14613 (2011)
10. V.K. Yechoor, M.E. Patti, K. Ueki, P.G. Laustsen, R. Saccone, R. Rauniyar, C.R. Kahn, Proc Natl Acad Sci USA 101(47), 16525–16530 (2004)
11. D. Zou, K. Chen, P. Liu, H. Chang, J. Zhu, M. Mi. Med. Sci. Sports Exerc. (2014)
12. M.L. Chen, L. Yi, X. Jin, X.Y. Liang, Y. Zhou, T. Zhang, Q. Xie, X. Zhou, H. Chang, Y.J. Fu, J.D. Zhu, Q.Y. Zhang, M.T. Mi, Autophagy 9(12), 2033–2045 (2013)
13. K. Sawada, K. Kawabata, T. Yamashita, K. Kawasaki, N. Yamamoto, H. Ashida, Lipids Health Dis 11, 36 (2012)
14. D.J. Powell, S. Turban, A. Gray, E. Hajduch, H.S. Hundal, Biochem. J. 382(Pt 2), 619–629 (2004)
15. J.J. Senn, J. Biol. Chem. 281(37), 26865–26875 (2006)
16. C. Schmitz-Peiffer, D.L. Craig, T.J. Biden, J. Biol. Chem. 274(34), 24202–24210 (1999)
17. B. Levine, G. Kroemer, Cell 132(1), 27–42 (2008)
18. H.S. Jung, K.W. Chung, K.J. Won, J. Kim, M. Komatsu, K. Tanaka, Y.H. Nguyen, T.M. Kang, K.H. Yoon, J.W. Kim, Y.T. Jeong, M.S. Han, M.K. Lee, K.W. Kim, J. Shin, M.S. Lee, Cell Metab. 8(4), 318–324 (2008)
19. C. Ebato, T. Uchida, M. Arakawa, M. Komatsu, T. Ueno, K. Komiya, K. Azuma, T. Hirose, K. Tanaka, E. Kominami, R. Kawamori, Y. Fujitani, H. Watada, Cell Metab. 8(4), 325–332 (2008)
20. H.Y. Liu, J. Han, S.Y. Cao, T. Hong, D. Zhuo, J. Shi, Z. Liu, W. Cao, J. Biol. Chem. 284(45), 31484–31492 (2009)
21. R. Singh, S. Kaushik, Y. Wang, Y. Xiang, I. Novak, M. Komatsu, K. Tanaka, A.M. Cuervo, M.J. Czaja, Nature 458(7242), 1131–1135 (2009)
22. T. Yoshizaki, C. Kusunoki, M. Kondo, M. Yasuda, S. Kume, K. Morino, O. Sekine, S. Ugi, T. Uzu, Y. Nishio, A. Kashiwagi, H. Maegawa, Biochem. Biophys. Res. Commun. 417(1), 352–357 (2012)
23. C. He, M.C. Bassik, V. Moresi, K. Sun, Y. Wei, Z. Zou, Z. An, J. Loh, J. Fisher, Q. Sun, S. Korsmeyer, M. Packer, H.I. May, J.A. Hill, H.W. Virgin, C. Gilpin, G. Xiao, R. Bassel-Duby, P.E. Scherer, B. Levine, Nature 481(7382), 511–515 (2012)
24. Q. Meng, D. Cai, J. Biol. Chem. 286(37), 32324–32332 (2011)
25. S. Kume, M.C. Thomas, D. Koya, Diabetes 61(1), 23–29 (2012)
26. K.H. Kim, Y.T. Jeong, H. Oh, S.H. Kim, J.M. Cho, Y.N. Kim, S.S. Kim, D.H. Kim, K.Y. Hur, H.K. Kim, T. Ko, J. Han, H.L. Kim, J. Kim, S.H. Back, M. Komatsu, H. Chen, D.C. Chan, M. Konishi, N. Itoh, C.S. Choi, M.S. Lee, Nat. Med. 19(1), 83–92 (2013)
27. S. Imai, F.B. Johnson, R.A. Marciniak, M. McVey, P.U. Park, L. Guarente, Cold Spring Harb. Symp. Quant. Biol. 65, 297–302 (2000)
28. P. Onyango, I. Celic, J.M. McCaffery, J.D. Boeke, A.P. Feinberg, Proc Natl Acad Sci USA 99(21), 13653–13658 (2002)
29. B. Schwer, B.J. North, R.A. Frye, M. Ott, E. Verdin, J. Cell Biol. 158(4), 647–657 (2002)
30. E. Jing, B. Emanuelli, M.D. Hirschey, J. Boucher, K.Y. Lee, D. Lombard, E.M. Verdin, C.R. Kahn, Proc Natl Acad Sci USA 108(35), 14608–14613 (2011)
31. S.J. Park, F. Ahmad, A. Philp, K. Baar, T. Williams, H. Luo, H. Ke, H. Rehmann, R. Taussig, A.L. Brown, M.K. Kim, M.A. Beaven, A.B. Burgin, V. Manganiello, J.H. Chung, Cell 148(3), 421–433 (2012)