-
1
-
-
2142662186
-
Multiple sclerosis
-
Hafler D.A. Multiple sclerosis. J. Clin. Invest. 2004, 113:788-794.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 788-794
-
-
Hafler, D.A.1
-
2
-
-
33749059726
-
The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration
-
Hauser S.L., Oksenberg J.R. The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron 2006, 52:61-76.
-
(2006)
Neuron
, vol.52
, pp. 61-76
-
-
Hauser, S.L.1
Oksenberg, J.R.2
-
3
-
-
84921334544
-
The meninges: new therapeutic targets for multiple sclerosis
-
Russi A.E., Brown M.A. The meninges: new therapeutic targets for multiple sclerosis. Transl. Res. 2015, 165:255-269.
-
(2015)
Transl. Res.
, vol.165
, pp. 255-269
-
-
Russi, A.E.1
Brown, M.A.2
-
4
-
-
34247108119
-
Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis
-
Brown D.A., Sawchenko P.E. Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis. J. Comp. Neurol. 2007, 502:236-260.
-
(2007)
J. Comp. Neurol.
, vol.502
, pp. 236-260
-
-
Brown, D.A.1
Sawchenko, P.E.2
-
5
-
-
65649096159
-
Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis
-
Kivisakk P., Imitola J., Rasmussen S., Elyaman W., Zhu B., Ransohoff R.M., Khoury S.J. Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann. Neurol. 2009, 65:457-469.
-
(2009)
Ann. Neurol.
, vol.65
, pp. 457-469
-
-
Kivisakk, P.1
Imitola, J.2
Rasmussen, S.3
Elyaman, W.4
Zhu, B.5
Ransohoff, R.M.6
Khoury, S.J.7
-
6
-
-
84920934493
-
Dynamic changes in meningeal inflammation correspond to clinical exacerbations in a murine model of relapsing-remitting multiple sclerosis
-
Walker-Caulfield M.E., Hatfield J.K., Brown M.A. Dynamic changes in meningeal inflammation correspond to clinical exacerbations in a murine model of relapsing-remitting multiple sclerosis. J. Neuroimmunol. 2015, 278:112-122.
-
(2015)
J. Neuroimmunol.
, vol.278
, pp. 112-122
-
-
Walker-Caulfield, M.E.1
Hatfield, J.K.2
Brown, M.A.3
-
7
-
-
16244380177
-
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
-
Greter M., Heppner F.L., Lemos M.P., Odermatt B.M., Goebels N., Laufer T., Noelle R.J., Becher B. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat. Med. 2005, 11:328-334.
-
(2005)
Nat. Med.
, vol.11
, pp. 328-334
-
-
Greter, M.1
Heppner, F.L.2
Lemos, M.P.3
Odermatt, B.M.4
Goebels, N.5
Laufer, T.6
Noelle, R.J.7
Becher, B.8
-
8
-
-
84877132598
-
Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE
-
Christy A.L., Walker M.E., Hessner M.J., Brown M.A. Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE. J. Autoimmun. 2013, 42:50-61.
-
(2013)
J. Autoimmun.
, vol.42
, pp. 50-61
-
-
Christy, A.L.1
Walker, M.E.2
Hessner, M.J.3
Brown, M.A.4
-
9
-
-
77953639372
-
Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment?
-
Sayed B.A., Christy A.L., Walker M.E., Brown M.A. Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment?. J. Immunol. 2010, 184:6891-6900.
-
(2010)
J. Immunol.
, vol.184
, pp. 6891-6900
-
-
Sayed, B.A.1
Christy, A.L.2
Walker, M.E.3
Brown, M.A.4
-
10
-
-
0037828315
-
Subpial demyelination in the cerebral cortex of multiple sclerosis patients
-
Bo L., Vedeler C.A., Nyland H.I., Trapp B.D., Mork S.J. Subpial demyelination in the cerebral cortex of multiple sclerosis patients. J. Neuropathol. Exp. Neurol. 2003, 62:723-732.
-
(2003)
J. Neuropathol. Exp. Neurol.
, vol.62
, pp. 723-732
-
-
Bo, L.1
Vedeler, C.A.2
Nyland, H.I.3
Trapp, B.D.4
Mork, S.J.5
-
11
-
-
33847227721
-
Widespread demyelination in the cerebellar cortex in multiple sclerosis
-
Kutzelnigg A., Faber-Rod J.C., Bauer J., Lucchinetti C.F., Sorensen P.S., Laursen H., Stadelmann C., Bruck W., Rauschka H., Schmidbauer M., Lassmann H. Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol. 2007, 17:38-44.
-
(2007)
Brain Pathol.
, vol.17
, pp. 38-44
-
-
Kutzelnigg, A.1
Faber-Rod, J.C.2
Bauer, J.3
Lucchinetti, C.F.4
Sorensen, P.S.5
Laursen, H.6
Stadelmann, C.7
Bruck, W.8
Rauschka, H.9
Schmidbauer, M.10
Lassmann, H.11
-
12
-
-
27644552194
-
Cortical demyelination and diffuse white matter injury in multiple sclerosis
-
Kutzelnigg A., Lucchinetti C.F., Stadelmann C., Bruck W., Rauschka H., Bergmann M., Schmidbauer M., Parisi J.E., Lassmann H. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005, 128:2705-2712.
-
(2005)
Brain
, vol.128
, pp. 2705-2712
-
-
Kutzelnigg, A.1
Lucchinetti, C.F.2
Stadelmann, C.3
Bruck, W.4
Rauschka, H.5
Bergmann, M.6
Schmidbauer, M.7
Parisi, J.E.8
Lassmann, H.9
-
13
-
-
83155173565
-
Inflammatory cortical demyelination in early multiple sclerosis
-
Lucchinetti C.F., Popescu B.F., Bunyan R.F., Moll N.M., Roemer S.F., Lassmann H., Bruck W., Parisi J.E., Scheithauer B.W., Giannini C., Weigand S.D., Mandrekar J., Ransohoff R.M. Inflammatory cortical demyelination in early multiple sclerosis. N. Engl. J. Med. 2011, 365:2188-2197.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 2188-2197
-
-
Lucchinetti, C.F.1
Popescu, B.F.2
Bunyan, R.F.3
Moll, N.M.4
Roemer, S.F.5
Lassmann, H.6
Bruck, W.7
Parisi, J.E.8
Scheithauer, B.W.9
Giannini, C.10
Weigand, S.D.11
Mandrekar, J.12
Ransohoff, R.M.13
-
14
-
-
84886684533
-
The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells
-
Heath W.R., Carbone F.R. The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells. Nat. Immunol. 2013, 14:978-985.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 978-985
-
-
Heath, W.R.1
Carbone, F.R.2
-
15
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald T.T., Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005, 307:1920-1925.
-
(2005)
Science
, vol.307
, pp. 1920-1925
-
-
Macdonald, T.T.1
Monteleone, G.2
-
16
-
-
84907487375
-
Innate receptors and cellular defense against pulmonary infections
-
Werner J.L., Steele C. Innate receptors and cellular defense against pulmonary infections. J. Immunol. 2014, 193:3842-3850.
-
(2014)
J. Immunol.
, vol.193
, pp. 3842-3850
-
-
Werner, J.L.1
Steele, C.2
-
17
-
-
77957257149
-
Novel characterization of monocyte-derived cell populations in the meninges and choroid plexus and their rates of replenishment in bone marrow chimeric mice
-
Chinnery H.R., Ruitenberg M.J., McMenamin P.G. Novel characterization of monocyte-derived cell populations in the meninges and choroid plexus and their rates of replenishment in bone marrow chimeric mice. J. Neuropathol. Exp. Neurol. 2010, 69:896-909.
-
(2010)
J. Neuropathol. Exp. Neurol.
, vol.69
, pp. 896-909
-
-
Chinnery, H.R.1
Ruitenberg, M.J.2
McMenamin, P.G.3
-
18
-
-
70449102882
-
Immunology: in the beginning
-
Ransohoff R.M. Immunology: in the beginning. Nature 2009, 462:41-42.
-
(2009)
Nature
, vol.462
, pp. 41-42
-
-
Ransohoff, R.M.1
-
19
-
-
0142259710
-
Three or more routes for leukocyte migration into the central nervous system
-
Ransohoff R.M., Kivisakk P., Kidd G. Three or more routes for leukocyte migration into the central nervous system. Nat. Rev. Immunol. 2003, 3:569-581.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 569-581
-
-
Ransohoff, R.M.1
Kivisakk, P.2
Kidd, G.3
-
20
-
-
84907983938
-
Innate lymphoid cells in inflammation and immunity
-
McKenzie A.N., Spits H., Eberl G. Innate lymphoid cells in inflammation and immunity. Immunity 2014, 41:366-374.
-
(2014)
Immunity
, vol.41
, pp. 366-374
-
-
McKenzie, A.N.1
Spits, H.2
Eberl, G.3
-
21
-
-
84875218285
-
Innate lymphoid cells: from border protection to the initiation of inflammatory diseases
-
Sanos S.L., Diefenbach A. Innate lymphoid cells: from border protection to the initiation of inflammatory diseases. Immunol. Cell Biol. 2013, 91:215-224.
-
(2013)
Immunol. Cell Biol.
, vol.91
, pp. 215-224
-
-
Sanos, S.L.1
Diefenbach, A.2
-
22
-
-
84872977452
-
Innate lymphoid cells - a proposal for uniform nomenclature
-
Spits H., Artis D., Colonna M., Diefenbach A., Di Santo J.P., Eberl G., Koyasu S., Locksley R.M., McKenzie A.N., Mebius R.E., Powrie F., Vivier E. Innate lymphoid cells - a proposal for uniform nomenclature. Nat. Rev. Immunol. 2013, 13:145-149.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 145-149
-
-
Spits, H.1
Artis, D.2
Colonna, M.3
Diefenbach, A.4
Di Santo, J.P.5
Eberl, G.6
Koyasu, S.7
Locksley, R.M.8
McKenzie, A.N.9
Mebius, R.E.10
Powrie, F.11
Vivier, E.12
-
23
-
-
58149384437
-
Critical role of ROR-gammat in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation
-
Michel M.L., Mendes-da-Cruz D., Keller A.C., Lochner M., Schneider E., Dy M., Eberl G., Leite-de-Moraes M.C. Critical role of ROR-gammat in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation. Proc. Natl. Acad. Sci. USA 2008, 105:19845-19850.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19845-19850
-
-
Michel, M.L.1
Mendes-da-Cruz, D.2
Keller, A.C.3
Lochner, M.4
Schneider, E.5
Dy, M.6
Eberl, G.7
Leite-de-Moraes, M.C.8
-
24
-
-
84859384082
-
Innate lymphoid cells: emerging insights in development, lineage relationships, and function
-
Spits H., Cupedo T. Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu. Rev. Immunol. 2012, 30:647-675.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 647-675
-
-
Spits, H.1
Cupedo, T.2
-
25
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
-
Sutton C.E., Lalor S.J., Sweeney C.M., Brereton C.F., Lavelle E.C., Mills K.H. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
26
-
-
33748588423
-
Littman, The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov B.S., McKenzie L., Zhou C.E., Tadokoro A., Lepelley J.J., Lafaille D.J., Cua D.R. Littman, The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, B.S.1
McKenzie, L.2
Zhou, C.E.3
Tadokoro, A.4
Lepelley, J.J.5
Lafaille, D.J.6
Cua, D.R.7
-
27
-
-
66249140545
-
Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity
-
Greter M., Hofmann J., Becher B. Neo-lymphoid aggregates in the adult liver can initiate potent cell-mediated immunity. PLoS Biol. 2009, 7:e1000109.
-
(2009)
PLoS Biol.
, vol.7
, pp. e1000109
-
-
Greter, M.1
Hofmann, J.2
Becher, B.3
-
28
-
-
0030856118
-
A critical role for lymphotoxin in experimental allergic encephalomyelitis
-
Suen W.E., Bergman C.M., Hjelmstrom P., Ruddle N.H. A critical role for lymphotoxin in experimental allergic encephalomyelitis. J. Exp. Med. 1997, 186:1233-1240.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1233-1240
-
-
Suen, W.E.1
Bergman, C.M.2
Hjelmstrom, P.3
Ruddle, N.H.4
-
29
-
-
84865411384
-
Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue
-
Withers D.R., Gaspal F.M., Mackley E.C., Marriott C.L., Ross E.A., Desanti G.E., Roberts N.A., White A.J., Flores-Langarica A., McConnell F.M., Anderson G., Lane P.J. Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue. J. Immunol. 2012, 189:2094-2098.
-
(2012)
J. Immunol.
, vol.189
, pp. 2094-2098
-
-
Withers, D.R.1
Gaspal, F.M.2
Mackley, E.C.3
Marriott, C.L.4
Ross, E.A.5
Desanti, G.E.6
Roberts, N.A.7
White, A.J.8
Flores-Langarica, A.9
McConnell, F.M.10
Anderson, G.11
Lane, P.J.12
-
30
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang X.O., Pappu B.P., Nurieva R., Akimzhanov A., Kang H.S., Chung Y., Ma L., Shah B., Panopoulos A.D., Schluns K.S., Watowich S.S., Tian Q., Jetten A.M., Dong C. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 2008, 28:29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
Ma, L.7
Shah, B.8
Panopoulos, A.D.9
Schluns, K.S.10
Watowich, S.S.11
Tian, Q.12
Jetten, A.M.13
Dong, C.14
-
31
-
-
0038523790
-
Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis
-
Bettelli E., Pagany M., Weiner H.L., Linington C., Sobel R.A., Kuchroo V.K. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J. Exp. Med. 2003, 197:1073-1081.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1073-1081
-
-
Bettelli, E.1
Pagany, M.2
Weiner, H.L.3
Linington, C.4
Sobel, R.A.5
Kuchroo, V.K.6
-
32
-
-
77951878587
-
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
-
Buonocore S., Ahern P.P., Uhlig H.H., Ivanov I.I., Littman D.R., Maloy K.J., Powrie F. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 2010, 464:1371-1375.
-
(2010)
Nature
, vol.464
, pp. 1371-1375
-
-
Buonocore, S.1
Ahern, P.P.2
Uhlig, H.H.3
Ivanov, I.I.4
Littman, D.R.5
Maloy, K.J.6
Powrie, F.7
-
33
-
-
48749091530
-
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut
-
Tsuji M., Suzuki K., Kitamura H., Maruya M., Kinoshita K., Ivanov I.I., Itoh K., Littman D.R., Fagarasan S. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 2008, 29:261-271.
-
(2008)
Immunity
, vol.29
, pp. 261-271
-
-
Tsuji, M.1
Suzuki, K.2
Kitamura, H.3
Maruya, M.4
Kinoshita, K.5
Ivanov, I.I.6
Itoh, K.7
Littman, D.R.8
Fagarasan, S.9
-
34
-
-
84871597188
-
Cytokine control of inflammation and repair in the pathology of multiple sclerosis
-
Rodgers J.M., Miller S.D. Cytokine control of inflammation and repair in the pathology of multiple sclerosis. Yale J. Biol. Med. 2012, 85:447-468.
-
(2012)
Yale J. Biol. Med.
, vol.85
, pp. 447-468
-
-
Rodgers, J.M.1
Miller, S.D.2
-
35
-
-
79956116032
-
RORgammat drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
-
Codarri L., Gyulveszi G., Tosevski V., Hesske L., Fontana A., Magnenat L., Suter T., Becher B. RORgammat drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat. Immunol. 2011, 12:560-567.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 560-567
-
-
Codarri, L.1
Gyulveszi, G.2
Tosevski, V.3
Hesske, L.4
Fontana, A.5
Magnenat, L.6
Suter, T.7
Becher, B.8
-
36
-
-
79956152607
-
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
-
El-Behi M., Ciric B., Dai H., Yan Y., Cullimore M., Safavi F., Zhang G.X., Dittel B.N., Rostami A. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol. 2011, 12:568-575.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 568-575
-
-
El-Behi, M.1
Ciric, B.2
Dai, H.3
Yan, Y.4
Cullimore, M.5
Safavi, F.6
Zhang, G.X.7
Dittel, B.N.8
Rostami, A.9
-
37
-
-
77950482945
-
Memory CD4 T cells: generation, reactivation and re-assignment
-
MacLeod M.K., Kappler J.W., Marrack P. Memory CD4 T cells: generation, reactivation and re-assignment. Immunology 2010, 130:10-15.
-
(2010)
Immunology
, vol.130
, pp. 10-15
-
-
MacLeod, M.K.1
Kappler, J.W.2
Marrack, P.3
-
38
-
-
84891493325
-
Autoimmune effector memory T cells: the bad and the good
-
Devarajan P., Chen Z. Autoimmune effector memory T cells: the bad and the good. Immunol. Res. 2013, 57:12-22.
-
(2013)
Immunol. Res.
, vol.57
, pp. 12-22
-
-
Devarajan, P.1
Chen, Z.2
-
39
-
-
48749103314
-
Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis
-
Elyaman W., Kivisakk P., Reddy J., Chitnis T., Raddassi K., Imitola J., Bradshaw E., Kuchroo V.K., Yagita H., Sayegh M.H., Khoury S.J. Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. Am. J. Pathol. 2008, 173:411-422.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 411-422
-
-
Elyaman, W.1
Kivisakk, P.2
Reddy, J.3
Chitnis, T.4
Raddassi, K.5
Imitola, J.6
Bradshaw, E.7
Kuchroo, V.K.8
Yagita, H.9
Sayegh, M.H.10
Khoury, S.J.11
-
40
-
-
80054856205
-
OX40 and CD30 signals in CD4(+) T-cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4(+) T-cell memory but not effector function
-
Withers D.R., Gaspal F.M., Bekiaris V., McConnell F.M., Kim M., Anderson G., Lane P.J. OX40 and CD30 signals in CD4(+) T-cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4(+) T-cell memory but not effector function. Immunol. Rev. 2011, 244:134-148.
-
(2011)
Immunol. Rev.
, vol.244
, pp. 134-148
-
-
Withers, D.R.1
Gaspal, F.M.2
Bekiaris, V.3
McConnell, F.M.4
Kim, M.5
Anderson, G.6
Lane, P.J.7
-
41
-
-
84867718489
-
Stem cell factor receptor/c-Kit: from basic science to clinical implications
-
Lennartsson J., Ronnstrand L. Stem cell factor receptor/c-Kit: from basic science to clinical implications. Physiol. Rev. 2012, 92:1619-1649.
-
(2012)
Physiol. Rev.
, vol.92
, pp. 1619-1649
-
-
Lennartsson, J.1
Ronnstrand, L.2
-
42
-
-
84907968021
-
Development, differentiation, and diversity of innate lymphoid cells
-
Diefenbach A., Colonna M., Koyasu S. Development, differentiation, and diversity of innate lymphoid cells. Immunity 2014, 41:354-365.
-
(2014)
Immunity
, vol.41
, pp. 354-365
-
-
Diefenbach, A.1
Colonna, M.2
Koyasu, S.3
-
43
-
-
0023213914
-
Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo
-
Galli S.J., Kitamura Y. Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo. Am. J. Pathol. 1987, 127:191-198.
-
(1987)
Am. J. Pathol.
, vol.127
, pp. 191-198
-
-
Galli, S.J.1
Kitamura, Y.2
-
44
-
-
0025334596
-
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W
-
Nocka K., Tan J.C., Chiu E., Chu T.Y., Ray P., Traktman P., Besmer P. Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J. 1990, 9:1805-1813.
-
(1990)
EMBO J.
, vol.9
, pp. 1805-1813
-
-
Nocka, K.1
Tan, J.C.2
Chiu, E.3
Chu, T.Y.4
Ray, P.5
Traktman, P.6
Besmer, P.7
-
45
-
-
0014469150
-
Decreased neutrophils and megakaryocytes in anemic mice of genotype W/W
-
Chervenick P.A., Boggs D.R. Decreased neutrophils and megakaryocytes in anemic mice of genotype W/W. J. Cell. Physiol. 1969, 73:25-30.
-
(1969)
J. Cell. Physiol.
, vol.73
, pp. 25-30
-
-
Chervenick, P.A.1
Boggs, D.R.2
-
46
-
-
78649823490
-
Kit ligand and Il7 differentially regulate Peyer's patch and lymph node development
-
Chappaz S., Gartner C., Rodewald H.R., Finke D. Kit ligand and Il7 differentially regulate Peyer's patch and lymph node development. J. Immunol. 2010, 185:3514-3519.
-
(2010)
J. Immunol.
, vol.185
, pp. 3514-3519
-
-
Chappaz, S.1
Gartner, C.2
Rodewald, H.R.3
Finke, D.4
-
47
-
-
79953176981
-
Cutting edge: mast cells regulate disease severity in a relapsing-remitting model of multiple sclerosis
-
Sayed B.A., Walker M.E., Brown M.A. Cutting edge: mast cells regulate disease severity in a relapsing-remitting model of multiple sclerosis. J. Immunol. 2011, 186:3294-3298.
-
(2011)
J. Immunol.
, vol.186
, pp. 3294-3298
-
-
Sayed, B.A.1
Walker, M.E.2
Brown, M.A.3
-
48
-
-
0034610971
-
Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis
-
Secor V.H., Secor W.E., Gutekunst C.A., Brown M.A. Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis. J. Exp. Med. 2000, 191:813-822.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 813-822
-
-
Secor, V.H.1
Secor, W.E.2
Gutekunst, C.A.3
Brown, M.A.4
-
49
-
-
42249114634
-
The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease
-
Carlson T., Kroenke M., Rao P., Lane T.E., Segal B. The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. J. Exp. Med. 2008, 205:811-823.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 811-823
-
-
Carlson, T.1
Kroenke, M.2
Rao, P.3
Lane, T.E.4
Segal, B.5
-
50
-
-
33846018916
-
GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis
-
Ponomarev E.D., Shriver L.P., Maresz K., Pedras-Vasconcelos J., Verthelyi D., Dittel B.N. GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J. Immunol. 2007, 178:39-48.
-
(2007)
J. Immunol.
, vol.178
, pp. 39-48
-
-
Ponomarev, E.D.1
Shriver, L.P.2
Maresz, K.3
Pedras-Vasconcelos, J.4
Verthelyi, D.5
Dittel, B.N.6
-
51
-
-
15444378040
-
Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory
-
Gaspal F.M., Kim M.Y., McConnell F.M., Raykundalia C., Bekiaris V., Lane P.J. Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory. J. Immunol. 2005, 174:3891-3896.
-
(2005)
J. Immunol.
, vol.174
, pp. 3891-3896
-
-
Gaspal, F.M.1
Kim, M.Y.2
McConnell, F.M.3
Raykundalia, C.4
Bekiaris, V.5
Lane, P.J.6
-
52
-
-
0038066310
-
CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells
-
Kim M.Y., Gaspal F.M., Wiggett H.E., McConnell F.M., Gulbranson-Judge A., Raykundalia C., Walker L.S., Goodall M.D., Lane P.J. CD4(+)CD3(-) accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells. Immunity 2003, 18:643-654.
-
(2003)
Immunity
, vol.18
, pp. 643-654
-
-
Kim, M.Y.1
Gaspal, F.M.2
Wiggett, H.E.3
McConnell, F.M.4
Gulbranson-Judge, A.5
Raykundalia, C.6
Walker, L.S.7
Goodall, M.D.8
Lane, P.J.9
-
53
-
-
77954116318
-
The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals
-
Withers D.R., Jaensson E., Gaspal F., McConnell F.M., Eksteen B., Anderson G., Agace W.W., Lane P.J. The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals. J. Immunol. 2009, 183:5079-5084.
-
(2009)
J. Immunol.
, vol.183
, pp. 5079-5084
-
-
Withers, D.R.1
Jaensson, E.2
Gaspal, F.3
McConnell, F.M.4
Eksteen, B.5
Anderson, G.6
Agace, W.W.7
Lane, P.J.8
-
54
-
-
0034843773
-
Ectopic lymphoid organogenesis: a fast track for autoimmunity
-
Weyand C.M., Kurtin P.J., Goronzy J.J. Ectopic lymphoid organogenesis: a fast track for autoimmunity. Am. J. Pathol. 2001, 159:787-793.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 787-793
-
-
Weyand, C.M.1
Kurtin, P.J.2
Goronzy, J.J.3
-
55
-
-
78649857216
-
Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look
-
Aloisi F., Serafini B., Magliozzi R., Howell O.W., Reynolds R. Detection of Epstein-Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look. Brain 2010, 133:e157.
-
(2010)
Brain
, vol.133
, pp. e157
-
-
Aloisi, F.1
Serafini, B.2
Magliozzi, R.3
Howell, O.W.4
Reynolds, R.5
-
56
-
-
0034842962
-
Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers
-
Armengol M.P., Juan M., Lucas-Martin A., Fernandez-Figueras M.T., Jaraquemada D., Gallart T., Pujol-Borrell R. Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers. Am. J. Pathol. 2001, 159:861-873.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 861-873
-
-
Armengol, M.P.1
Juan, M.2
Lucas-Martin, A.3
Fernandez-Figueras, M.T.4
Jaraquemada, D.5
Gallart, T.6
Pujol-Borrell, R.7
-
57
-
-
34249700046
-
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
-
Magliozzi R., Howell O., Vora A., Serafini B., Nicholas R., Puopolo M., Reynolds R., Aloisi F. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 2007, 130:1089-1104.
-
(2007)
Brain
, vol.130
, pp. 1089-1104
-
-
Magliozzi, R.1
Howell, O.2
Vora, A.3
Serafini, B.4
Nicholas, R.5
Puopolo, M.6
Reynolds, R.7
Aloisi, F.8
-
58
-
-
2442708947
-
Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis
-
Serafini B., Rosicarelli B., Magliozzi R., Stigliano E., Aloisi F. Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. Brain Pathol. 2004, 14:164-174.
-
(2004)
Brain Pathol.
, vol.14
, pp. 164-174
-
-
Serafini, B.1
Rosicarelli, B.2
Magliozzi, R.3
Stigliano, E.4
Aloisi, F.5
-
59
-
-
0032402246
-
The role of CD8+ CD40L+ T cells in the formation of germinal centers in rheumatoid synovitis
-
Wagner U.G., Kurtin P.J., Wahner A., Brackertz M., Berry D.J., Goronzy J.J., Weyand C.M. The role of CD8+ CD40L+ T cells in the formation of germinal centers in rheumatoid synovitis. J. Immunol. 1998, 161:6390-6397.
-
(1998)
J. Immunol.
, vol.161
, pp. 6390-6397
-
-
Wagner, U.G.1
Kurtin, P.J.2
Wahner, A.3
Brackertz, M.4
Berry, D.J.5
Goronzy, J.J.6
Weyand, C.M.7
-
60
-
-
0038240921
-
Ectopic germinal center formation in rheumatoid synovitis
-
Weyand C.M., Goronzy J.J. Ectopic germinal center formation in rheumatoid synovitis. Ann. N. Y. Acad. Sci. 2003, 987:140-149.
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.987
, pp. 140-149
-
-
Weyand, C.M.1
Goronzy, J.J.2
-
61
-
-
34247617232
-
Tertiary lymphoid structures in the pancreas promote selection of B lymphocytes in autoimmune diabetes
-
Kendall P.L., Yu G., Woodward E.J., Thomas J.W. Tertiary lymphoid structures in the pancreas promote selection of B lymphocytes in autoimmune diabetes. J. Immunol. 2007, 178:5643-5651.
-
(2007)
J. Immunol.
, vol.178
, pp. 5643-5651
-
-
Kendall, P.L.1
Yu, G.2
Woodward, E.J.3
Thomas, J.W.4
-
62
-
-
78149481589
-
Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords
-
Androdias G., Reynolds R., Chanal M., Ritleng C., Confavreux C., Nataf S. Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords. Ann. Neurol. 2010, 68:465-476.
-
(2010)
Ann. Neurol.
, vol.68
, pp. 465-476
-
-
Androdias, G.1
Reynolds, R.2
Chanal, M.3
Ritleng, C.4
Confavreux, C.5
Nataf, S.6
-
63
-
-
80052927697
-
Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
-
Howell O.W., Reeves C.A., Nicholas R., Carassiti D., Radotra B., Gentleman S.M., Serafini B., Aloisi F., Roncaroli F., Magliozzi R., Reynolds R. Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. Brain 2011, 134:2755-2771.
-
(2011)
Brain
, vol.134
, pp. 2755-2771
-
-
Howell, O.W.1
Reeves, C.A.2
Nicholas, R.3
Carassiti, D.4
Radotra, B.5
Gentleman, S.M.6
Serafini, B.7
Aloisi, F.8
Roncaroli, F.9
Magliozzi, R.10
Reynolds, R.11
-
64
-
-
84865791246
-
A role for Th17 cells in the regulation of tertiary lymphoid follicles
-
Grogan J.L., Ouyang W. A role for Th17 cells in the regulation of tertiary lymphoid follicles. Eur. J. Immunol. 2012, 42:2255-2262.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 2255-2262
-
-
Grogan, J.L.1
Ouyang, W.2
-
65
-
-
84899530446
-
The development and function of mucosal lymphoid tissues: a balancing act with micro-organisms
-
Randall T.D., Mebius R.E. The development and function of mucosal lymphoid tissues: a balancing act with micro-organisms. Mucosal Immunol. 2014, 7:455-466.
-
(2014)
Mucosal Immunol.
, vol.7
, pp. 455-466
-
-
Randall, T.D.1
Mebius, R.E.2
-
66
-
-
33748963586
-
Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin beta receptor-Ig fusion protein
-
Columba-Cabezas S., Griguoli M., Rosicarelli B., Magliozzi R., Ria F., Serafini B., Aloisi F. Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin beta receptor-Ig fusion protein. J. Neuroimmunol. 2006, 179:76-86.
-
(2006)
J. Neuroimmunol.
, vol.179
, pp. 76-86
-
-
Columba-Cabezas, S.1
Griguoli, M.2
Rosicarelli, B.3
Magliozzi, R.4
Ria, F.5
Serafini, B.6
Aloisi, F.7
-
67
-
-
84878372569
-
Tertiary lymphoid organ development coincides with determinant spreading of the myelin-specific T cell response
-
Kuerten S., Schickel A., Kerkloh C., Recks M.S., Addicks K., Ruddle N.H., Lehmann P.V. Tertiary lymphoid organ development coincides with determinant spreading of the myelin-specific T cell response. Acta Neuropathol. 2012, 124:861-873.
-
(2012)
Acta Neuropathol.
, vol.124
, pp. 861-873
-
-
Kuerten, S.1
Schickel, A.2
Kerkloh, C.3
Recks, M.S.4
Addicks, K.5
Ruddle, N.H.6
Lehmann, P.V.7
-
68
-
-
62849102106
-
Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
-
van Zwam M., Huizinga R., Heijmans N., van Meurs M., Wierenga-Wolf A.F., Melief M.J., Hintzen R.Q., t Hart B.A., Amor S., Boven L.A., Laman J.D. Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis. J. Pathol. 2009, 217:543-551.
-
(2009)
J. Pathol.
, vol.217
, pp. 543-551
-
-
van Zwam, M.1
Huizinga, R.2
Heijmans, N.3
van Meurs, M.4
Wierenga-Wolf, A.F.5
Melief, M.J.6
Hintzen, R.Q.7
t Hart, B.A.8
Amor, S.9
Boven, L.A.10
Laman, J.D.11
-
69
-
-
53149111593
-
Invariant NKT cells regulate experimental autoimmune encephalomyelitis and infiltrate the central nervous system in a CD1d-independent manner
-
Mars L.T., Gautron A.S., Novak J., Beaudoin L., Diana J., Liblau R.S., Lehuen A. Invariant NKT cells regulate experimental autoimmune encephalomyelitis and infiltrate the central nervous system in a CD1d-independent manner. J. Immunol. 2008, 181:2321-2329.
-
(2008)
J. Immunol.
, vol.181
, pp. 2321-2329
-
-
Mars, L.T.1
Gautron, A.S.2
Novak, J.3
Beaudoin, L.4
Diana, J.5
Liblau, R.S.6
Lehuen, A.7
-
70
-
-
0035905485
-
Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis
-
Jahng A.W., Maricic I., Pedersen B., Burdin N., Naidenko O., Kronenberg M., Koezuka Y., Kumar V. Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis. J. Exp. Med. 2001, 194:1789-1799.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1789-1799
-
-
Jahng, A.W.1
Maricic, I.2
Pedersen, B.3
Burdin, N.4
Naidenko, O.5
Kronenberg, M.6
Koezuka, Y.7
Kumar, V.8
-
71
-
-
0035807302
-
A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
-
Miyamoto K., Miyake S., Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001, 413:531-534.
-
(2001)
Nature
, vol.413
, pp. 531-534
-
-
Miyamoto, K.1
Miyake, S.2
Yamamura, T.3
-
72
-
-
4644221871
-
Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids
-
Parekh V.V., Singh A.K., Wilson M.T., Olivares-Villagomez D., Bezbradica J.S., Inazawa H., Ehara H., Sakai T., Serizawa I., Wu L., Wang C.R., Joyce S., Van Kaer L. Quantitative and qualitative differences in the in vivo response of NKT cells to distinct alpha- and beta-anomeric glycolipids. J. Immunol. 2004, 173:3693-3706.
-
(2004)
J. Immunol.
, vol.173
, pp. 3693-3706
-
-
Parekh, V.V.1
Singh, A.K.2
Wilson, M.T.3
Olivares-Villagomez, D.4
Bezbradica, J.S.5
Inazawa, H.6
Ehara, H.7
Sakai, T.8
Serizawa, I.9
Wu, L.10
Wang, C.R.11
Joyce, S.12
Van Kaer, L.13
-
73
-
-
84874226238
-
Activated invariant NKT cells control central nervous system autoimmunity in a mechanism that involves myeloid-derived suppressor cells
-
Parekh V.V., Wu L., Olivares-Villagomez D., Wilson K.T., Van Kaer L. Activated invariant NKT cells control central nervous system autoimmunity in a mechanism that involves myeloid-derived suppressor cells. J. Immunol. 2013, 190:1948-1960.
-
(2013)
J. Immunol.
, vol.190
, pp. 1948-1960
-
-
Parekh, V.V.1
Wu, L.2
Olivares-Villagomez, D.3
Wilson, K.T.4
Van Kaer, L.5
-
74
-
-
0035905471
-
Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis
-
Singh A.K., Wilson M.T., Hong S., Olivares-Villagomez D., Du C., Stanic A.K., Joyce S., Sriram S., Koezuka Y., Van Kaer L. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J. Exp. Med. 2001, 194:1801-1811.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1801-1811
-
-
Singh, A.K.1
Wilson, M.T.2
Hong, S.3
Olivares-Villagomez, D.4
Du, C.5
Stanic, A.K.6
Joyce, S.7
Sriram, S.8
Koezuka, Y.9
Van Kaer, L.10
-
75
-
-
79959564984
-
Invariant NKT cells producing IL-4 or IL-10, but not IFN-gamma, inhibit the Th1 response in experimental autoimmune encephalomyelitis, whereas none of these cells inhibits the Th17 response
-
Oh S.J., Chung D.H. Invariant NKT cells producing IL-4 or IL-10, but not IFN-gamma, inhibit the Th1 response in experimental autoimmune encephalomyelitis, whereas none of these cells inhibits the Th17 response. J. Immunol. 2011, 186:6815-6821.
-
(2011)
J. Immunol.
, vol.186
, pp. 6815-6821
-
-
Oh, S.J.1
Chung, D.H.2
-
76
-
-
77951214891
-
Role of the innate immune system in the pathogenesis of multiple sclerosis
-
Gandhi R., Laroni A., Weiner H.L. Role of the innate immune system in the pathogenesis of multiple sclerosis. J. Neuroimmunol. 2010, 221:7-14.
-
(2010)
J. Neuroimmunol.
, vol.221
, pp. 7-14
-
-
Gandhi, R.1
Laroni, A.2
Weiner, H.L.3
-
77
-
-
77957021670
-
Gammadelta T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism
-
Petermann F., Rothhammer V., Claussen M.C., Haas J.D., Blanco L.R., Heink S., Prinz I., Hemmer B., Kuchroo V.K., Oukka M., Korn T. Gammadelta T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism. Immunity 2010, 33:351-363.
-
(2010)
Immunity
, vol.33
, pp. 351-363
-
-
Petermann, F.1
Rothhammer, V.2
Claussen, M.C.3
Haas, J.D.4
Blanco, L.R.5
Heink, S.6
Prinz, I.7
Hemmer, B.8
Kuchroo, V.K.9
Oukka, M.10
Korn, T.11
-
78
-
-
84892447769
-
Thy1+ Sca1+ innate lymphoid cells infiltrate the CNS during autoimmune inflammation, but do not contribute to disease development
-
Mair F., Becher B. Thy1+ Sca1+ innate lymphoid cells infiltrate the CNS during autoimmune inflammation, but do not contribute to disease development. Eur. J. Immunol. 2014, 44:37-45.
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 37-45
-
-
Mair, F.1
Becher, B.2
-
79
-
-
84864558396
-
Inhibition of LTi cell development by CD25 blockade is associated with decreased intrathecal inflammation in multiple sclerosis
-
145ra106
-
Perry J.S., Han S., Xu Q., Herman M.L., Kennedy L.B., Csako G., Bielekova B. Inhibition of LTi cell development by CD25 blockade is associated with decreased intrathecal inflammation in multiple sclerosis. Sci. Transl. Med. 2012, 4:145ra106.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Perry, J.S.1
Han, S.2
Xu, Q.3
Herman, M.L.4
Kennedy, L.B.5
Csako, G.6
Bielekova, B.7
|