메뉴 건너뛰기




Volumn 173, Issue 2, 2008, Pages 411-422

Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; BIOLOGICAL MARKER; CD134 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; HERMES ANTIGEN; INTERLEUKIN 17; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

EID: 48749103314     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2008.080142     Document Type: Article
Times cited : (52)

References (59)
  • 1
    • 0033786776 scopus 로고    scopus 로고
    • Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
    • Bielekova B, Goodwin B, Richert N, Cortese I, Kondo T, Afshar G, Gran B, Eaton J, Antel J, Frank JA, McFarland HF, Martin R: Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat Med 2000, 6:1167-1175
    • (2000) Nat Med , vol.6 , pp. 1167-1175
    • Bielekova, B.1    Goodwin, B.2    Richert, N.3    Cortese, I.4    Kondo, T.5    Afshar, G.6    Gran, B.7    Eaton, J.8    Antel, J.9    Frank, J.A.10    McFarland, H.F.11    Martin, R.12
  • 2
    • 30344437563 scopus 로고    scopus 로고
    • Insights into the molecular pathogenesis of progression in multiple sclerosis: Potential implications for future therapies
    • Imitola J, Chitnis T, Khoury SJ: Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies. Arch Neurol 2006, 63:25-33
    • (2006) Arch Neurol , vol.63 , pp. 25-33
    • Imitola, J.1    Chitnis, T.2    Khoury, S.J.3
  • 3
    • 0026079842 scopus 로고
    • Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis
    • Selmaj K, Brosnan CF, Raine CS: Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis, Proc Natl Acad Sci USA 1991, 88:6452-6456
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6452-6456
    • Selmaj, K.1    Brosnan, C.F.2    Raine, C.S.3
  • 4
    • 5344228374 scopus 로고    scopus 로고
    • Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease
    • Weiner HL: Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease. Arch Neurol 2004, 61:1613-1615
    • (2004) Arch Neurol , vol.61 , pp. 1613-1615
    • Weiner, H.L.1
  • 5
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang J, Markovic-Plese S, Lacet B, Raus J, Weiner HL, Hafler DA: Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J Exp Med 1994, 179:973-984
    • (1994) J Exp Med , vol.179 , pp. 973-984
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3    Raus, J.4    Weiner, H.L.5    Hafler, D.A.6
  • 6
    • 0025138302 scopus 로고
    • T cells responsive to myelin basic protein in patients with multiple sclerosis
    • Allegretta M, Nicklas JA, Sriram S, Albertini RJ: T cells responsive to myelin basic protein in patients with multiple sclerosis. Science 1990, 247:718-721
    • (1990) Science , vol.247 , pp. 718-721
    • Allegretta, M.1    Nicklas, J.A.2    Sriram, S.3    Albertini, R.J.4
  • 7
    • 0032519421 scopus 로고    scopus 로고
    • Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells
    • Lovett-Racke AE, Trotter JL, Lauber J, Perrin PJ, June CH, Racke MK: Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells. J Clin Invest 1998, 101:725-730
    • (1998) J Clin Invest , vol.101 , pp. 725-730
    • Lovett-Racke, A.E.1    Trotter, J.L.2    Lauber, J.3    Perrin, P.J.4    June, C.H.5    Racke, M.K.6
  • 9
    • 0031892792 scopus 로고    scopus 로고
    • Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation
    • Scholz C, Patton KT, Anderson DE, Freeman GJ, Hafler DA: Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation. J Immunol 1998, 160:1532-1538
    • (1998) J Immunol , vol.160 , pp. 1532-1538
    • Scholz, C.1    Patton, K.T.2    Anderson, D.E.3    Freeman, G.J.4    Hafler, D.A.5
  • 10
    • 0042320414 scopus 로고    scopus 로고
    • Memory T cells: A hurdle to immunologic tolerance
    • Lakkis FG, Sayegh MH: Memory T cells: a hurdle to immunologic tolerance. J Am Soc Nephrol 2003, 14:2402-2410
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2402-2410
    • Lakkis, F.G.1    Sayegh, M.H.2
  • 12
    • 0036550559 scopus 로고    scopus 로고
    • Effector and memory T-cell differentiation: Implications for vaccine development
    • Kaech SM, Wherry EJ, Ahmed R: Effector and memory T-cell differentiation: implications for vaccine development. Nat Rev Immunol 2002, 2:251-262
    • (2002) Nat Rev Immunol , vol.2 , pp. 251-262
    • Kaech, S.M.1    Wherry, E.J.2    Ahmed, R.3
  • 13
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust D, Vezys V, Marzo AL, Lefrancois L: Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001, 291:2413-2417
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 14
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt RL, Khoruts A, Merica R, Zell T, Jenkins MK: Visualizing the generation of memory CD4 T cells in the whole body. Nature 2001, 410:101-105
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 15
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A: Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 16
    • 0242660096 scopus 로고    scopus 로고
    • Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis
    • quiz 850
    • Chitnis T, Khoury SJ: Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis, J Allergy Clin Immunol 2003, 112:837-849 quiz 850
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 837-849
    • Chitnis, T.1    Khoury, S.J.2
  • 17
    • 16244389649 scopus 로고    scopus 로고
    • The B7/CD28 costimulatory family in autoimmunity
    • Keir ME, Sharpe AH: The B7/CD28 costimulatory family in autoimmunity. Immunol Rev 2005, 204:128-143
    • (2005) Immunol Rev , vol.204 , pp. 128-143
    • Keir, M.E.1    Sharpe, A.H.2
  • 18
    • 2442461055 scopus 로고    scopus 로고
    • The roles of the new negative T cell costimulatory pathways in regulating autoimmunity
    • Khoury SJ, Sayegh MH: The roles of the new negative T cell costimulatory pathways in regulating autoimmunity. Immunity 2004, 20:529-538
    • (2004) Immunity , vol.20 , pp. 529-538
    • Khoury, S.J.1    Sayegh, M.H.2
  • 19
    • 0028316562 scopus 로고
    • Naïve versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells
    • Croft M, Bradley LM, Swain SL: Naïve versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J Immunol 1994, 152:2675-2685
    • (1994) J Immunol , vol.152 , pp. 2675-2685
    • Croft, M.1    Bradley, L.M.2    Swain, S.L.3
  • 20
    • 0033975857 scopus 로고    scopus 로고
    • Functional responses and costimulator dependence of memory CD4+ T cells
    • London CA, Lodge MP, Abbas AK: Functional responses and costimulator dependence of memory CD4+ T cells. J Immunol 2000, 164:265-272
    • (2000) J Immunol , vol.164 , pp. 265-272
    • London, C.A.1    Lodge, M.P.2    Abbas, A.K.3
  • 23
    • 0034789247 scopus 로고    scopus 로고
    • Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
    • Chitnis T, Najafian N, Benou C, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ: Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J Clin Invest 2001, 108:739-747
    • (2001) J Clin Invest , vol.108 , pp. 739-747
    • Chitnis, T.1    Najafian, N.2    Benou, C.3    Salama, A.D.4    Grusby, M.J.5    Sayegh, M.H.6    Khoury, S.J.7
  • 26
    • 0037037568 scopus 로고    scopus 로고
    • Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells
    • Judge AD, Zhang X, Fujii H, Surh CD, Sprent J: Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med 2002, 196:935-946
    • (2002) J Exp Med , vol.196 , pp. 935-946
    • Judge, A.D.1    Zhang, X.2    Fujii, H.3    Surh, C.D.4    Sprent, J.5
  • 28
    • 0033581935 scopus 로고    scopus 로고
    • Selecting and maintaining a diverse T-cell repertoire
    • Goldrath AW, Bevan MJ: Selecting and maintaining a diverse T-cell repertoire. Nature 1999, 402:255-262
    • (1999) Nature , vol.402 , pp. 255-262
    • Goldrath, A.W.1    Bevan, M.J.2
  • 29
    • 0034911054 scopus 로고    scopus 로고
    • Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage
    • Werner P, Pitt D, Raine CS: Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage. Ann Neurol 2001, 50:169-180
    • (2001) Ann Neurol , vol.50 , pp. 169-180
    • Werner, P.1    Pitt, D.2    Raine, C.S.3
  • 30
    • 0019137326 scopus 로고
    • Glial cells in the enteric nervous system contain glial fibrillary acidic protein
    • Jessen KR, Mirsky R: Glial cells in the enteric nervous system contain glial fibrillary acidic protein. Nature 1980, 286:736-737
    • (1980) Nature , vol.286 , pp. 736-737
    • Jessen, K.R.1    Mirsky, R.2
  • 31
    • 0028868424 scopus 로고
    • CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system
    • Khoury SJ, Akalin E, Chandraker A, Turka LA, Linsley PS, Sayegh MH, Hancock WW: CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system. J Immunol 1995, 155:4521-4524
    • (1995) J Immunol , vol.155 , pp. 4521-4524
    • Khoury, S.J.1    Akalin, E.2    Chandraker, A.3    Turka, L.A.4    Linsley, P.S.5    Sayegh, M.H.6    Hancock, W.W.7
  • 33
    • 33644517535 scopus 로고    scopus 로고
    • Patients, pathogens, and protective immunity: The relevance of virus-induced alloreactivity in transplantation
    • Koehn B, Gangappa S, Miller JD, Ahmed R, Larsen CP: Patients, pathogens, and protective immunity: the relevance of virus-induced alloreactivity in transplantation. J Immunol 2006, 176:2691-2696
    • (2006) J Immunol , vol.176 , pp. 2691-2696
    • Koehn, B.1    Gangappa, S.2    Miller, J.D.3    Ahmed, R.4    Larsen, C.P.5
  • 35
    • 0030934465 scopus 로고    scopus 로고
    • Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling
    • Vincenz C, Dixit VM: Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. J Biol Chem 1997, 272:6578-6583
    • (1997) J Biol Chem , vol.272 , pp. 6578-6583
    • Vincenz, C.1    Dixit, V.M.2
  • 37
    • 3242726945 scopus 로고    scopus 로고
    • CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer
    • Callahan MK, Williams KA, Kivisakk P, Pearce D, Stins MF, Ransohoff RM: CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer. J Neuroimmunol 2004, 153:150-157
    • (2004) J Neuroimmunol , vol.153 , pp. 150-157
    • Callahan, M.K.1    Williams, K.A.2    Kivisakk, P.3    Pearce, D.4    Stins, M.F.5    Ransohoff, R.M.6
  • 40
    • 0042333469 scopus 로고    scopus 로고
    • CXCR3 is induced early on the pathway of CD4+ T cell differentiation and bridges central and peripheral functions
    • Rabin RL, Alston MA, Sircus JC, Knollmann-Ritschel B, Moratz C, Ngo D, Farber JM: CXCR3 is induced early on the pathway of CD4+ T cell differentiation and bridges central and peripheral functions. J Immunol 2003, 171:2812-2824
    • (2003) J Immunol , vol.171 , pp. 2812-2824
    • Rabin, R.L.1    Alston, M.A.2    Sircus, J.C.3    Knollmann-Ritschel, B.4    Moratz, C.5    Ngo, D.6    Farber, J.M.7
  • 43
    • 0038623916 scopus 로고    scopus 로고
    • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
    • Nakae S, Saijo S, Horai R, Sudo K, Mori S, Iwakura Y: IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist. Proc Natl Acad Sci USA 2003, 100:5986-5990
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5986-5990
    • Nakae, S.1    Saijo, S.2    Horai, R.3    Sudo, K.4    Mori, S.5    Iwakura, Y.6
  • 44
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005, 6:1123-1132
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 46
    • 0029800836 scopus 로고    scopus 로고
    • Memory alloreactive cytotoxic T cells do not require costimulation for activation in vitro
    • Flynn K, Mullbacher A: Memory alloreactive cytotoxic T cells do not require costimulation for activation in vitro. Immunol Cell Biol 1996, 74:413-420
    • (1996) Immunol Cell Biol , vol.74 , pp. 413-420
    • Flynn, K.1    Mullbacher, A.2
  • 47
    • 0032589334 scopus 로고    scopus 로고
    • Differential requirements of naïve and memory T cells for CD28 costimulation in autoimmune pathogenesis
    • Perrin PJ, Lovett-Racke A, Phillips SM, Racke MK: Differential requirements of naïve and memory T cells for CD28 costimulation in autoimmune pathogenesis. Histol Histopathol 1999, 14:1269-1276
    • (1999) Histol Histopathol , vol.14 , pp. 1269-1276
    • Perrin, P.J.1    Lovett-Racke, A.2    Phillips, S.M.3    Racke, M.K.4
  • 48
    • 0028999041 scopus 로고
    • Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation
    • Cross AH, Girard TJ, Giacoletto KS, Evans RJ, Keeling RM, Lin RF, Trotter JL, Karr RW: Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation. J Clin Invest 1995, 95:2783-2789
    • (1995) J Clin Invest , vol.95 , pp. 2783-2789
    • Cross, A.H.1    Girard, T.J.2    Giacoletto, K.S.3    Evans, R.J.4    Keeling, R.M.5    Lin, R.F.6    Trotter, J.L.7    Karr, R.W.8
  • 49
    • 0030587810 scopus 로고    scopus 로고
    • Ex vivo treatment of antigen-presenting cells with CTLA4Ig and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat
    • Khoury SJ, Gallon L, Verburg RR, Chandraker A, Peach R, Linsley PS, Turka LA, Hancock WW, Sayegh MH: Ex vivo treatment of antigen-presenting cells with CTLA4Ig and encephalitogenic peptide prevents experimental autoimmune encephalomyelitis in the Lewis rat. J Immunol 1996, 157:3700-3705
    • (1996) J Immunol , vol.157 , pp. 3700-3705
    • Khoury, S.J.1    Gallon, L.2    Verburg, R.R.3    Chandraker, A.4    Peach, R.5    Linsley, P.S.6    Turka, L.A.7    Hancock, W.W.8    Sayegh, M.H.9
  • 52
    • 2942715184 scopus 로고    scopus 로고
    • Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection
    • Vu MD, Amanullah F, Li Y, Demirci G, Sayegh MH, Li XC: Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection. J Immunol 2004, 173:214-221
    • (2004) J Immunol , vol.173 , pp. 214-221
    • Vu, M.D.1    Amanullah, F.2    Li, Y.3    Demirci, G.4    Sayegh, M.H.5    Li, X.C.6
  • 55
    • 0032534582 scopus 로고    scopus 로고
    • Ox-40 ligand: A potent costimulatory molecule for sustaining primary CD4 T cell responses
    • Gramaglia I, Weinberg AD, Lemon M, Croft M: Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses. J Immunol 1998, 161:6510-6517
    • (1998) J Immunol , vol.161 , pp. 6510-6517
    • Gramaglia, I.1    Weinberg, A.D.2    Lemon, M.3    Croft, M.4
  • 57
    • 8444234229 scopus 로고    scopus 로고
    • 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses
    • Dawicki W, Bertram EM, Sharpe AH, Watts TH: 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses. J Immunol 2004, 173:5944-5951
    • (2004) J Immunol , vol.173 , pp. 5944-5951
    • Dawicki, W.1    Bertram, E.M.2    Sharpe, A.H.3    Watts, T.H.4
  • 59
    • 31144460031 scopus 로고    scopus 로고
    • Critical, but conditional, role of OX40 in memory T cell-mediated rejection
    • Vu MD, Clarkson MR, Yagita H, Turka LA, Sayegh MH, Li XC: Critical, but conditional, role of OX40 in memory T cell-mediated rejection. J Immunol 2006, 176:1394-1401
    • (2006) J Immunol , vol.176 , pp. 1394-1401
    • Vu, M.D.1    Clarkson, M.R.2    Yagita, H.3    Turka, L.A.4    Sayegh, M.H.5    Li, X.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.