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Volumn 190, Issue 5, 2013, Pages 1948-1960

Activated invariant NKT cells control central nervous system autoimmunity in a mechanism that involves myeloid-derived suppressor cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; ARGINASE 1; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 4;

EID: 84874226238     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201718     Document Type: Article
Times cited : (51)

References (63)
  • 2
    • 0038228956 scopus 로고    scopus 로고
    • The regulatory role of Valpha14 NKT cells in innate and acquired immune response
    • Taniguchi, M., M. Harada, S. Kojo, T. Nakayama, and H. Wakao. 2003. The regulatory role of Valpha14 NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 21: 483-513.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 483-513
    • Taniguchi, M.1    Harada, M.2    Kojo, S.3    Nakayama, T.4    Wakao, H.5
  • 3
    • 17144374753 scopus 로고    scopus 로고
    • Toward an understanding of NKT cell biology: Progress and paradoxes
    • Kronenberg, M. 2005. Toward an understanding of NKT cell biology: progress and paradoxes. Annu. Rev. Immunol. 23: 877-900.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 877-900
    • Kronenberg, M.1
  • 4
    • 2542448243 scopus 로고    scopus 로고
    • CD1: Antigen presentation and T cell function
    • Brigl, M., and M. B. Brenner. 2004. CD1: antigen presentation and T cell function. Annu. Rev. Immunol. 22: 817-890.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 817-890
    • Brigl, M.1    Brenner, M.B.2
  • 5
    • 34047177067 scopus 로고    scopus 로고
    • The in vivo response of invariant natural killer T cells to glycolipid antigens
    • Parekh, V. V., S. Lalani, and L. Van Kaer. 2007. The in vivo response of invariant natural killer T cells to glycolipid antigens. Int. Rev. Immunol. 26: 31-48.
    • (2007) Int. Rev. Immunol. , vol.26 , pp. 31-48
    • Parekh, V.V.1    Lalani, S.2    Van Kaer, L.3
  • 6
    • 45449103839 scopus 로고    scopus 로고
    • CD1drestricted iNKT cells, the 'Swiss-Army knife' of the immune system
    • Matsuda, J. L., T. Mallevaey, J. Scott-Browne, and L. Gapin. 2008. CD1drestricted iNKT cells, the 'Swiss-Army knife' of the immune system. Curr. Opin. Immunol. 20: 358-368.
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 358-368
    • Matsuda, J.L.1    Mallevaey, T.2    Scott-Browne, J.3    Gapin, L.4
  • 7
    • 78650575791 scopus 로고    scopus 로고
    • Invariant NK T cells: Potential for immunotherapeutic targeting with glycolipid antigens
    • Van Kaer, L., V. V. Parekh, and L. Wu. 2011. Invariant NK T cells: potential for immunotherapeutic targeting with glycolipid antigens. Immunotherapy 3: 59-75.
    • (2011) Immunotherapy , vol.3 , pp. 59-75
    • Van Kaer, L.1    Parekh, V.V.2    Wu., L.3
  • 8
    • 79051471632 scopus 로고    scopus 로고
    • Invariant natural killer T cells bridging innate and adaptive immunity
    • Van Kaer, L., V. V. Parekh, and L. Wu. 2011. Invariant natural killer T cells: bridging innate and adaptive immunity. Cell Tissue Res. 343: 43-55.
    • (2011) Cell Tissue Res , vol.343 , pp. 43-55
    • Van Kaer, L.1    Parekh, V.V.2    Wu., L.3
  • 9
    • 11244304412 scopus 로고    scopus 로고
    • A-Galactosylceramide therapy for autoimmune diseases: Prospects and obstacles
    • Van Kaer, L. 2005. a-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles. Nat. Rev. Immunol. 5: 31-42.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 31-42
    • Van Kaer, L.1
  • 10
    • 0037364854 scopus 로고    scopus 로고
    • Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity
    • Wilson, S. B., and T. L. Delovitch. 2003. Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nat. Rev. Immunol. 3: 211-222.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 211-222
    • Wilson, S.B.1    Delovitch, T.L.2
  • 12
    • 84873130090 scopus 로고    scopus 로고
    • Invariant natural killer T cells as sensors and managers of inflammation
    • DOI: 10.1016/j. it.2012.08.009
    • Van Kaer, L, and V V Parekh, and W. L. 2012. Invariant natural killer T cells as sensors and managers of inflammation. Trends Immunol. DOI: 10.1016/j. it.2012.08.009.
    • (2012) Trends Immunol.
    • Van Kaer, L.1    Parekh, V.V.2
  • 15
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto, K., S. Miyake, and T. Yamamura. 2001. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 413: 531-534.
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 17
    • 0035159618 scopus 로고    scopus 로고
    • Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of v alpha 14 NK T cells
    • Pál, E., T. Tabira, T. Kawano, M. Taniguchi, S. Miyake, and T. Yamamura. 2001. Costimulation-dependent modulation of experimental autoimmune encephalomyelitis by ligand stimulation of V alpha 14 NK T cells. J. Immunol. 166: 662-668.
    • (2001) J. Immunol. , vol.166 , pp. 662-668
    • Pál, E.1    Tabira, T.2    Kawano, T.3    Taniguchi, M.4    Miyake, S.5    Yamamura, T.6
  • 18
    • 0041968838 scopus 로고    scopus 로고
    • Activation of invariant NKT cells by alpha- GalCer administration protects mice from MOG35-55-induced EAE: Critical roles for administration route and IFN-gamma
    • Furlan, R., A. Bergami, D. Cantarella, E. Brambilla, M. Taniguchi, P. Dellabona, G. Casorati, and G. Martino. 2003. Activation of invariant NKT cells by alpha- GalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma. Eur. J. Immunol. 33: 1830-1838.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1830-1838
    • Furlan, R.1    Bergami, A.2    Cantarella, D.3    Brambilla, E.4    Taniguchi, M.5    Dellabona, P.6    Casorati, G.7    Martino, G.8
  • 20
    • 67149115417 scopus 로고    scopus 로고
    • Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4
    • Bunt, S. K., V. K. Clements, E. M. Hanson, P. Sinha, and S. Ostrand-Rosenberg. 2009. Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4. J. Leukoc. Biol. 85: 996-1004.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 996-1004
    • Bunt, S.K.1    Clements, V.K.2    Hanson, E.M.3    Sinha, P.4    Ostrand-Rosenberg, S.5
  • 21
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich, D. I., and S. Nagaraj. 2009. Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9: 162-174.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 22
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • Youn, J. I., S. Nagaraj, M. Collazo, and D. I. Gabrilovich. 2008. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181: 5791-5802.
    • (2008) J. Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 23
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by Larginine metabolism
    • Bronte, V., and P. Zanovello. 2005. Regulation of immune responses by Larginine metabolism. Nat. Rev. Immunol. 5: 641-654.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 25
    • 70350545729 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in inflammation: Uncovering cell subsets with enhanced immunosuppressive functions
    • Bronte, V. 2009. Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions. Eur. J. Immunol. 39: 2670-2672.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2670-2672
    • Bronte, V.1
  • 26
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • Rodriguez, P. C., M. S. Ernstoff, C. Hernandez, M. Atkins, J. Zabaleta, R. Sierra, and A. C. Ochoa. 2009. Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res. 69: 1553-1560.
    • (2009) Cancer Res. , vol.69 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3    Atkins, M.4    Zabaleta, J.5    Sierra, R.6    Ochoa, A.C.7
  • 27
    • 0030962696 scopus 로고    scopus 로고
    • CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4
    • Mendiratta, S. K., W. D. Martin, S. Hong, A. Boesteanu, S. Joyce, and L. Van Kaer. 1997. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6: 469-477.
    • (1997) Immunity , vol.6 , pp. 469-477
    • Mendiratta, S.K.1    Martin, W.D.2    Hong, S.3    Boesteanu, A.4    Joyce, S.5    Van Kaer, L.6
  • 28
    • 34248650931 scopus 로고    scopus 로고
    • Passive induction of experimental allergic encephalomyelitis
    • Stromnes, I. M., and J. M. Goverman. 2006. Passive induction of experimental allergic encephalomyelitis. Nat. Protoc. 1: 1952-1960.
    • (2006) Nat. Protoc. , vol.1 , pp. 1952-1960
    • Stromnes, I.M.1    Goverman, J.M.2
  • 30
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki, E., V. Kapoor, A. S. Jassar, L. R. Kaiser, and S. M. Albelda. 2005. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin. Cancer Res. 11: 6713-6721.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 31
    • 34547630506 scopus 로고    scopus 로고
    • A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model
    • Ko, H. J., Y. J. Kim, Y. S. Kim, W. S. Chang, S. Y. Ko, S. Y. Chang, S. Sakaguchi, and C. Y. Kang. 2007. A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model. Cancer Res. 67: 7477-7486.
    • (2007) Cancer Res. , vol.67 , pp. 7477-7486
    • Ko, H.J.1    Kim, Y.J.2    Kim, Y.S.3    Chang, W.S.4    Ko, S.Y.5    Chang, S.Y.6    Sakaguchi, S.7    Kang, C.Y.8
  • 32
    • 38449100026 scopus 로고    scopus 로고
    • CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis
    • Zhu, B., Y. Bando, S. Xiao, K. Yang, A. C. Anderson, V. K. Kuchroo, and S. J. Khoury. 2007. CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis. J. Immunol. 179: 5228-5237.
    • (2007) J. Immunol. , vol.179 , pp. 5228-5237
    • Zhu, B.1    Bando, Y.2    Xiao, S.3    Yang, K.4    Anderson, A.C.5    Kuchroo, V.K.6    Khoury, S.J.7
  • 33
    • 78649752513 scopus 로고    scopus 로고
    • Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis
    • Domingues, H. S., M. Mues, H. Lassmann, H. Wekerle, and G. Krishnamoorthy. 2010. Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis. PLoS ONE 5: e15531.
    • (2010) PLoS ONE , vol.5
    • Domingues, H.S.1    Mues, M.2    Lassmann, H.3    Wekerle, H.4    Krishnamoorthy, G.5
  • 34
    • 75749097320 scopus 로고    scopus 로고
    • Th1 and Th17 cells: Adversaries and collaborators
    • Damsker, J. M., A. M. Hansen, and R. R. Caspi. 2010. Th1 and Th17 cells: adversaries and collaborators. Ann. N. Y. Acad. Sci. 1183: 211-221.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1183 , pp. 211-221
    • Damsker, J.M.1    Hansen, A.M.2    Caspi, R.R.3
  • 35
    • 79958721221 scopus 로고    scopus 로고
    • Th17 cell, the new player of neuroinflammatory process in multiple sclerosis
    • Jadidi-Niaragh, F., and A. Mirshafiey. 2011. Th17 cell, the new player of neuroinflammatory process in multiple sclerosis. Scand. J. Immunol. 74: 1-13.
    • (2011) Scand. J. Immunol. , vol.74 , pp. 1-13
    • Jadidi-Niaragh, F.1    Mirshafiey, A.2
  • 36
    • 77949656747 scopus 로고    scopus 로고
    • Th17 cells in autoimmune demyelinating disease
    • Segal, B. M. 2010. Th17 cells in autoimmune demyelinating disease. Semin. Immunopathol. 32: 71-77.
    • (2010) Semin. Immunopathol. , vol.32 , pp. 71-77
    • Segal, B.M.1
  • 38
  • 43
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani, A., S. Sozzani, M. Locati, P. Allavena, and A. Sica. 2002. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 23: 549-555.
    • (2002) Trends Immunol. , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 44
    • 84858861533 scopus 로고    scopus 로고
    • Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
    • Guerrero, A. R., K. Uchida, H. Nakajima, S. Watanabe, M. Nakamura, W. E. Johnson, and H. Baba. 2012. Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice. J. Neuroinflammation 9: 40-55.
    • (2012) J. Neuroinflammation , vol.9 , pp. 40-55
    • Guerrero, A.R.1    Uchida, K.2    Nakajima, H.3    Watanabe, S.4    Nakamura, M.5    Johnson, W.E.6    Baba, H.7
  • 46
    • 0242514648 scopus 로고    scopus 로고
    • Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes, and their precursors
    • Biermann, H., B. Pietz, R. Dreier, K. W. Schmid, C. Sorg, and C. Sunderkötter. 1999. Murine leukocytes with ring-shaped nuclei include granulocytes, monocytes, and their precursors. J. Leukoc. Biol. 65: 217-231.
    • (1999) J. Leukoc. Biol. , vol.65 , pp. 217-231
    • Biermann, H.1    Pietz, B.2    Dreier, R.3    Schmid, K.W.4    Sorg, C.5    Sunderkötter, C.6
  • 49
    • 84863611784 scopus 로고    scopus 로고
    • Activation of invariant NKT cells in early phase of experimental autoimmune encephalomyelitis results in differentiation of Ly6Chi inflammatory monocyte to M2 macrophages and improved outcome
    • Denney, L., W. L. Kok, S. L. Cole, S. Sanderson, A. J. McMichael, and L. P. Ho. 2012. Activation of invariant NKT cells in early phase of experimental autoimmune encephalomyelitis results in differentiation of Ly6Chi inflammatory monocyte to M2 macrophages and improved outcome. J. Immunol. 189: 551-557.
    • (2012) J. Immunol. , vol.189 , pp. 551-557
    • Denney, L.1    Kok, W.L.2    Cole, S.L.3    Sanderson, S.4    McMichael, A.J.5    Ho, L.P.6
  • 51
    • 65149093082 scopus 로고    scopus 로고
    • Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
    • King, I. L., T. L. Dickendesher, and B. M. Segal. 2009. Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood 113: 3190-3197.
    • (2009) Blood , vol.113 , pp. 3190-3197
    • King, I.L.1    Dickendesher, T.L.2    Segal, B.M.3
  • 54
    • 0036319459 scopus 로고    scopus 로고
    • Ligand-activated natural killer T lymphocytes promptly produce IL-3 and GM-CSF in vivo: Relevance to peripheral myeloid recruitment
    • Leite-de-Moraes, M. C., M. Lisbonne, A. Arnould, F. Machavoine, A. Herbelin, M. Dy, and E. Schneider. 2002. Ligand-activated natural killer T lymphocytes promptly produce IL-3 and GM-CSF in vivo: relevance to peripheral myeloid recruitment. Eur. J. Immunol. 32: 1897-1904.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1897-1904
    • Leite-De-Moraes, M.C.1    Lisbonne, M.2    Arnould, A.3    MacHavoine, F.4    Herbelin, A.5    Dy, M.6    Schneider, E.7
  • 56
    • 57449088879 scopus 로고    scopus 로고
    • Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloidderived suppressor cells in mice and humans
    • De Santo, C., M. Salio, S. H. Masri, L. Y. Lee, T. Dong, A. O. Speak, S. Porubsky, S. Booth, N. Veerapen, G. S. Besra, et al. 2008. Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloidderived suppressor cells in mice and humans. J. Clin. Invest. 118: 4036-4048.
    • (2008) J. Clin. Invest. , vol.118 , pp. 4036-4048
    • De Santo, C.1    Salio, M.2    Masri, S.H.3    Lee, L.Y.4    Dong, T.5    Speak, A.O.6    Porubsky, S.7    Booth, S.8    Veerapen, N.9    Besra, G.S.10
  • 57
    • 61449220940 scopus 로고    scopus 로고
    • Immunosuppressive myeloid-derived suppressor cells can be converted into immunogenic APCs with the help of activated NKT cells: An alternative cellbased antitumor vaccine
    • Ko, H. J., J. M. Lee, Y. J. Kim, Y. S. Kim, K. A. Lee, and C. Y. Kang. 2009. Immunosuppressive myeloid-derived suppressor cells can be converted into immunogenic APCs with the help of activated NKT cells: an alternative cellbased antitumor vaccine. J. Immunol. 182: 1818-1828.
    • (2009) J. Immunol. , vol.182 , pp. 1818-1828
    • Ko, H.J.1    Lee, J.M.2    Kim, Y.J.3    Kim, Y.S.4    Lee, K.A.5    Kang, C.Y.6
  • 58
    • 79960549766 scopus 로고    scopus 로고
    • Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse
    • Kmieciak, M., D. Basu, K. K. Payne, A. Toor, A. Yacoub, X. Y. Wang, L. Smith, H. D. Bear, and M. H. Manjili. 2011. Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse. J. Immunol. 187: 708-717.
    • (2011) J. Immunol. , vol.187 , pp. 708-717
    • Kmieciak, M.1    Basu, D.2    Payne, K.K.3    Toor, A.4    Yacoub, A.5    Wang, X.Y.6    Smith, L.7    Bear, H.D.8    Manjili, M.H.9
  • 59
    • 0033541457 scopus 로고    scopus 로고
    • Induction of apoptosis in activated T cell blasts by suppressive macrophages: A possible immunotherapeutic approach for treatment of autoimmune disease
    • McIntosh, K. R., and D. B. Drachman. 1999. Induction of apoptosis in activated T cell blasts by suppressive macrophages: a possible immunotherapeutic approach for treatment of autoimmune disease. Cell. Immunol. 193: 24-35.
    • (1999) Cell. Immunol. , vol.193 , pp. 24-35
    • McIntosh, K.R.1    Drachman, D.B.2
  • 60
    • 56549105942 scopus 로고    scopus 로고
    • Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations
    • Kerr, E. C., B. J. Raveney, D. A. Copland, A. D. Dick, and L. B. Nicholson. 2008. Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. J. Autoimmun. 31: 354-361.
    • (2008) J. Autoimmun. , vol.31 , pp. 354-361
    • Kerr, E.C.1    Raveney, B.J.2    Copland, D.A.3    Dick, A.D.4    Nicholson, L.B.5
  • 61
    • 78851469543 scopus 로고    scopus 로고
    • Invariant NKT cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation
    • Oh, K., O. J. Byoun, D. I. Ham, Y. S. Kim, and D. S. Lee. 2011. Invariant NKT cells regulate experimental autoimmune uveitis through inhibition of Th17 differentiation. Eur. J. Immunol. 41: 392-402.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 392-402
    • Oh, K.1    Byoun, O.J.2    Ham, D.I.3    Kim, Y.S.4    Lee, D.S.5
  • 63
    • 0346458555 scopus 로고    scopus 로고
    • Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide
    • Chiba, A., S. Oki, K. Miyamoto, H. Hashimoto, T. Yamamura, and S. Miyake. 2004. Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide. Arthritis Rheum. 50: 305-313.
    • (2004) Arthritis Rheum. , vol.50 , pp. 305-313
    • Chiba, A.1    Oki, S.2    Miyamoto, K.3    Hashimoto, H.4    Yamamura, T.5    Miyake, S.6


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