AMPKα2 reduces renal epithelial transdifferentiation and inflammation after injury through interaction with CK2β

Journal of Pathology

Volumn 237, Issue 3, 2015, Pages 330-342

  Qiu, Shulan ^a,b,c   Xiao, Zhicheng ^a,b,c   Piao, Chunmei ^a,b,c   Zhang, Jing ^a,b,c   Dong, Yanjun ^a,b,c   Cui, Wei ^a,b,c   Liu, Xin ^d   Zhang, Youyi ^e   Du, Jie ^a,b,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c BEIJING INSTITUTE OF HEART   (China)

^d INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^e PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

AMPK 2; CK2 ; EMT; fibrosis; renal inflammation

Indexed keywords

BETA CATENIN; CASEIN KINASE II; CASEIN KINASE IIBETA; CHEMOKINE; CHEMOKINE KC; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; FIBRONECTIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA 2; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; SMAD3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AMPK ALPHA2 SUBUNIT, MOUSE; AUTACOID; CCL2 PROTEIN, MOUSE; CTNNB1 PROTEIN, MOUSE; CXCL1 CHEMOKINE; CXCL1 PROTEIN, MOUSE; PRKAA2 PROTEIN, HUMAN; PROTEIN BINDING; SMAD3 PROTEIN, MOUSE;

ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ARTICLE; CELL INFILTRATION; CELL STRUCTURE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATORY CELL; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; MOUSE; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; UPREGULATION; URETER OBSTRUCTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL LINE; COMPLICATION; DEFICIENCY; DISEASE MODEL; ENZYME ACTIVATION; ENZYMOLOGY; EPITHELIUM CELL; FIBROSIS; GENETICS; IMMUNOLOGY; KIDNEY PROXIMAL TUBULE; KNOCKOUT MOUSE; METABOLISM; NEPHRITIS, INTERSTITIAL; PATHOLOGY; RNA INTERFERENCE; WNT SIGNALING PATHWAY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BETA CATENIN; CASEIN KINASE II; CELL LINE; CELL TRANSDIFFERENTIATION; CHEMOKINE CCL2; CHEMOKINE CXCL1; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; HUMANS; INFLAMMATION MEDIATORS; KIDNEY TUBULES, PROXIMAL; MICE, INBRED C57BL; MICE, KNOCKOUT; NEPHRITIS, INTERSTITIAL; PROTEIN BINDING; RNA INTERFERENCE; SMAD3 PROTEIN; TRANSFECTION; URETERAL OBSTRUCTION; WNT SIGNALING PATHWAY;

EID: 84945473470     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4579     Document Type: Article

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