Complement 5a enhances hepatic metastases of colon cancer via monocyte chemoattractant protein-1-mediated inflammatory cell infiltration

Journal of Biological Chemistry

Volumn 290, Issue 17, 2015, Pages 10667-10676

  Piao, Chunmei ^a,b   Cai, Lun ^a   Qiu, Shulan ^a   Jia, Lixin ^a   Song, Wenchao ^a   Du, Jie ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BODY FLUIDS; CELL CULTURE; CELLS; CYTOLOGY; DISEASES; ENZYME INHIBITION; MOLECULES; MONOCLONAL ANTIBODIES; PROTEINS; TUMORS;

ANTI-INFLAMMATORIES; BONE MARROW TRANSPLANTATION; COLON CANCER CELLS; COMPLEMENT ACTIVATIONS; PHARMACOLOGICAL INHIBITION; SERUM-FREE CONDITIONS; THERAPEUTIC APPLICATION; TRANSFORMING GROWTH FACTOR BETA;

PATHOLOGY;

ARGINASE 1; CHEMOKINE; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 23P19; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1GAMMA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUBULIN; UNCLASSIFIED DRUG; CCL2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER CELL LINE; CELL INFILTRATION; COLON CANCER; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE MODEL; FEMALE; HUMAN; HUMAN CELL; INFLAMMATORY CELL; LIVER METASTASIS; MACROPHAGE; MALE; METASTASIS INHIBITION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; COLON TUMOR; DEFICIENCY; EXPERIMENTAL LIVER NEOPLASM; GENETICS; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; MACROPHAGE ACTIVATION; METABOLISM; PATHOLOGY; SECONDARY; TUMOR CELL LINE; TUMOR INVASION;

MURINAE;

ANIMALS; CELL LINE, TUMOR; CHEMOKINE CCL2; COLONIC NEOPLASMS; COMPLEMENT ACTIVATION; COMPLEMENT C5A; FEMALE; INFLAMMATION; LIVER NEOPLASMS, EXPERIMENTAL; MACROPHAGE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM INVASIVENESS; NEUTROPHIL INFILTRATION; RECEPTOR, ANAPHYLATOXIN C5A; TUMOR MICROENVIRONMENT;

EID: 84928404903     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.612622     Document Type: Article

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