A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 66, Issue 2, 2010, Pages 143-151

  Littler, Dene R ^a   Walker, John R ^a   Davis, Tara ^a   Wybenga Groot, Leanne E ^a   Finerty, Patrick J ^a   Newman, Elena ^a   MacKenzie, Farell ^a   Dhe Paganon, Sirano ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BINDING SITE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN FOLDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BINDING SITES; BIOCATALYSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SEQUENCE ALIGNMENT;

EUKARYOTA;

EID: 76349093842     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309109052543     Document Type: Article

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