메뉴 건너뛰기




Volumn 81, Issue 9, 2012, Pages 880-891

Tubular cell dedifferentiation and peritubular inflammation are coupled by the transcription regulator Id1 in renal fibrogenesis

Author keywords

EMT; Id1; inflammation; renal fibrosis; TGF 1

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF DIFFERENTIATION 1; RANTES; TRANSCRIPTION FACTOR SNAIL;

EID: 84862784957     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.469     Document Type: Article
Times cited : (23)

References (43)
  • 1
    • 33644638349 scopus 로고    scopus 로고
    • Renal fibrosis: New insights into the pathogenesis and therapeutics
    • DOI 10.1038/sj.ki.5000054, PII 5000054
    • Liu Y. Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int 2006; 69: 213-217. (Pubitemid 43323069)
    • (2006) Kidney International , vol.69 , Issue.2 , pp. 213-217
    • Liu, Y.1
  • 2
    • 78149298226 scopus 로고    scopus 로고
    • Mechanisms of tubulointerstitial fibrosis
    • Zeisberg M, Neilson EG. Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol 2010; 21: 1819-1834.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1819-1834
    • Zeisberg, M.1    Neilson, E.G.2
  • 3
    • 78049369136 scopus 로고    scopus 로고
    • Renal fibrosis: Novel insights into mechanisms and therapeutic targets
    • Boor P, Ostendorf T, Floege J. Renal fibrosis: novel insights into mechanisms and therapeutic targets. Nat Rev Nephrol 2010; 6: 643-656.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 643-656
    • Boor, P.1    Ostendorf, T.2    Floege, J.3
  • 4
    • 69849100333 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis
    • Li Y, Tan X, Dai C et al. Inhibition of integrin-linked kinase attenuates renal interstitial fibrosis. J Am Soc Nephrol 2009; 20: 1907-1918.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1907-1918
    • Li, Y.1    Tan, X.2    Dai, C.3
  • 5
    • 54749105918 scopus 로고    scopus 로고
    • Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kB signaling
    • Tan X, Wen X, Liu Y. Paricalcitol inhibits renal inflammation by promoting vitamin D receptor-mediated sequestration of NF-kB signaling. J Am Soc Nephrol 2008; 19: 1741-1752.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1741-1752
    • Tan, X.1    Wen, X.2    Liu, Y.3
  • 6
    • 77953885701 scopus 로고    scopus 로고
    • Targeting the recruitment of monocytes and macrophages in renal disease
    • Vielhauer V, Kulkarni O, Reichel CA et al. Targeting the recruitment of monocytes and macrophages in renal disease. Semin Nephrol 2010; 30: 318-333.
    • (2010) Semin Nephrol , vol.30 , pp. 318-333
    • Vielhauer, V.1    Kulkarni, O.2    Reichel, C.A.3
  • 7
    • 77955174530 scopus 로고    scopus 로고
    • Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction
    • Tapmeier TT, Fearn A, Brown K et al. Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction. Kidney Int 2010; 78: 351-362.
    • (2010) Kidney Int , vol.78 , pp. 351-362
    • Tapmeier, T.T.1    Fearn, A.2    Brown, K.3
  • 8
    • 46749083903 scopus 로고    scopus 로고
    • Hepatocyte growth factor exerts its anti-inflammatory action by disrupting nuclear factor-κB signaling
    • DOI 10.2353/ajpath.2008.070583
    • Giannopoulou M, Dai C, Tan X et al. Hepatocyte growth factor exerts its anti-inflammatory action by disrupting nuclear factor-kB signaling. Am J Pathol 2008; 173: 30-41. (Pubitemid 351947953)
    • (2008) American Journal of Pathology , vol.173 , Issue.1 , pp. 30-41
    • Giannopoulou, M.1    Dai, C.2    Tan, X.3    Wen, X.4    Michalopoulos, G.K.5    Liu, Y.6
  • 9
    • 70349694379 scopus 로고    scopus 로고
    • Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma
    • St John MA, Dohadwala M, Luo J et al. Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clin Cancer Res 2009; 15: 6018-6027.
    • (2009) Clin Cancer Res , vol.15 , pp. 6018-6027
    • St John, M.A.1    Dohadwala, M.2    Luo, J.3
  • 10
    • 70450142560 scopus 로고    scopus 로고
    • Inflammation and EMT: An alliance towards organ fibrosis and cancer progression
    • Lopez-Novoa JM, Nieto MA. Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol Med 2009; 1: 303-314.
    • (2009) EMBO Mol Med , vol.1 , pp. 303-314
    • Lopez-Novoa, J.M.1    Nieto, M.A.2
  • 11
    • 77951900538 scopus 로고    scopus 로고
    • Beyond epithelial to mesenchymal transition: A novel role for the transcription factor snail in inflammation and wound healing
    • Hotz B, Visekruna A, Buhr HJ et al. Beyond epithelial to mesenchymal transition: a novel role for the transcription factor snail in inflammation and wound healing. J Gastrointest Surg 2010; 14: 388-397.
    • (2010) J Gastrointest Surg , vol.14 , pp. 388-397
    • Hotz, B.1    Visekruna, A.2    Buhr, H.J.3
  • 12
    • 71149113180 scopus 로고    scopus 로고
    • Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy
    • Tan X, He W, Liu Y. Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy. Kidney Int 2009; 76: 1248-1257.
    • (2009) Kidney Int , vol.76 , pp. 1248-1257
    • Tan, X.1    He, W.2    Liu, Y.3
  • 13
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG et al. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell 2009; 15: 416-428.
    • (2009) Cancer Cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3
  • 14
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J, Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 2001; 159: 1465-1475. (Pubitemid 32947976)
    • (2001) American Journal of Pathology , vol.159 , Issue.4 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 15
    • 0347993932 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance, molecular mechanism, and therapeutic intervention
    • DOI 10.1097/01.ASN.0000106015.29070.E7
    • Liu Y. Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol 2004; 15: 1-12. (Pubitemid 38020692)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.1 , pp. 1-12
    • Liu, Y.1
  • 16
    • 23144464750 scopus 로고    scopus 로고
    • Id family of helix-loop-helix proteins in cancer
    • DOI 10.1038/nrc1673
    • Perk J, Iavarone A, Benezra R. Id family of helix-loop-helix proteins in cancer. Nat Rev Cancer 2005; 5: 603-614. (Pubitemid 41081386)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.8 , pp. 603-614
    • Perk, J.1    Iavarone, A.2    Benezra, R.3
  • 17
    • 33846684874 scopus 로고    scopus 로고
    • Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1
    • DOI 10.1681/ASN.2006030236
    • Li Y, Yang J, Luo JH et al. Tubular epithelial cell dedifferentiation is driven by the helix-loop-helix transcriptional inhibitor Id1. J Am Soc Nephrol 2007; 18: 449-460. (Pubitemid 46193311)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.2 , pp. 449-460
    • Li, Y.1    Yang, J.2    Luo, J.-H.3    Dedhar, S.4    Liu, Y.5
  • 18
    • 70449529854 scopus 로고    scopus 로고
    • KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer
    • Gumireddy K, Li A, Gimotty PA et al. KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Nat Cell Biol 2009; 11: 1297-1304.
    • (2009) Nat Cell Biol , vol.11 , pp. 1297-1304
    • Gumireddy, K.1    Li, A.2    Gimotty, P.A.3
  • 20
    • 15844397902 scopus 로고    scopus 로고
    • Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice
    • DOI 10.1097/01.ASN.0000139479.09658.EE
    • Dai C, Yang J, Bastacky S et al. Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice. J Am Soc Nephrol 2004; 15: 2637-2647. (Pubitemid 41103370)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.10 , pp. 2637-2647
    • Dai, C.1    Yang, J.2    Bastacky, S.3    Xia, J.4    Li, Y.5    Liu, Y.6
  • 21
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY et al. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3
  • 22
    • 80052335469 scopus 로고    scopus 로고
    • Targeted inhibition of {beta}-catenin/CBP signaling ameliorates renal interstitial fibrosis
    • Hao S, He W, Li Y et al. Targeted inhibition of {beta}-catenin/CBP signaling ameliorates renal interstitial fibrosis. J Am Soc Nephrol 2011; 22: 1642-1653.
    • (2011) J Am Soc Nephrol , vol.22 , pp. 1642-1653
    • Hao, S.1    He, W.2    Li, Y.3
  • 23
    • 33845242306 scopus 로고    scopus 로고
    • Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy
    • DOI 10.1681/ASN.2006050520
    • Tan X, Li Y, Liu Y. Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy. J Am Soc Nephrol 2006; 17: 3382-3393. (Pubitemid 44865281)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.12 , pp. 3382-3393
    • Tan, X.1    Li, Y.2    Liu, Y.3
  • 24
    • 0033554723 scopus 로고    scopus 로고
    • Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts
    • Lyden D, Young AZ, Zagzag D et al. Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature 1999; 401: 670-677.
    • (1999) Nature , vol.401 , pp. 670-677
    • Lyden, D.1    Young, A.Z.2    Zagzag, D.3
  • 25
    • 33847321490 scopus 로고    scopus 로고
    • Mechanisms of disease: Regulation of RANTES (CCL5) in renal disease
    • DOI 10.1038/ncpneph0418, PII NCPNEPH0418
    • Krensky AM, Ahn YT. Mechanisms of disease: regulation of RANTES (CCL5) in renal disease. Nat Clin Pract Nephrol 2007; 3: 164-170. (Pubitemid 46327139)
    • (2007) Nature Clinical Practice Nephrology , vol.3 , Issue.3 , pp. 164-170
    • Krensky, A.M.1    Ahn, Y.-T.2
  • 26
    • 36849007621 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling
    • DOI 10.1172/JCI32301
    • Hu K, Wu C, Mars WM et al. Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling. J Clin Invest 2007; 117: 3821-3832. (Pubitemid 350224092)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.12 , pp. 3821-3832
    • Hu, K.1    Wu, C.2    Mars, W.M.3    Liu, Y.4
  • 27
    • 79955979410 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts in renal fibrosis
    • Meran S, Steadman R. Fibroblasts and myofibroblasts in renal fibrosis. Int J Exp Pathol 2011; 92: 158-167.
    • (2011) Int J Exp Pathol , vol.92 , pp. 158-167
    • Meran, S.1    Steadman, R.2
  • 28
    • 79954570719 scopus 로고    scopus 로고
    • Myofibroblast differentiation during fibrosis: Role of NAD(P)H oxidases
    • Barnes JL, Gorin Y. Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases. Kidney Int 2011; 79: 944-956.
    • (2011) Kidney Int , vol.79 , pp. 944-956
    • Barnes, J.L.1    Gorin, Y.2
  • 29
    • 77953881058 scopus 로고    scopus 로고
    • Macrophages and immunologic inflammation of the kidney
    • Duffield JS. Macrophages and immunologic inflammation of the kidney. Semin Nephrol 2010; 30: 234-254.
    • (2010) Semin Nephrol , vol.30 , pp. 234-254
    • Duffield, J.S.1
  • 30
    • 63849257554 scopus 로고    scopus 로고
    • NF-kappaB signalling in chronic kidney disease
    • Rangan G, Wang Y, Harris D. NF-kappaB signalling in chronic kidney disease. Front Biosci 2009; 14: 3496-3522.
    • (2009) Front Biosci , vol.14 , pp. 3496-3522
    • Rangan, G.1    Wang, Y.2    Harris, D.3
  • 31
    • 55849103960 scopus 로고    scopus 로고
    • Macrophage diversity in renal injury and repair
    • Ricardo SD, van Goor H, Eddy AA. Macrophage diversity in renal injury and repair. J Clin Invest 2008; 118: 3522-3530.
    • (2008) J Clin Invest , vol.118 , pp. 3522-3530
    • Ricardo, S.D.1    Van Goor, H.2    Eddy, A.A.3
  • 33
    • 78649669329 scopus 로고    scopus 로고
    • Mechanistic connection between inflammation and fibrosis
    • Lee SB, Kalluri R. Mechanistic connection between inflammation and fibrosis. Kidney Int 2010; 78: S22-S26.
    • (2010) Kidney Int , vol.78
    • Lee, S.B.1    Kalluri, R.2
  • 34
    • 77949351029 scopus 로고    scopus 로고
    • New insights into epithelial-mesenchymal transition in kidney fibrosis
    • Liu Y. New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 2010; 21: 212-222.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 212-222
    • Liu, Y.1
  • 36
    • 53949096318 scopus 로고    scopus 로고
    • Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kappaB in MCF-7 breast cancer cells
    • Kim H, Chung H, Kim HJ et al. Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kappaB in MCF-7 breast cancer cells. Breast Cancer Res Treat 2008; 112: 287-296.
    • (2008) Breast Cancer Res Treat , vol.112 , pp. 287-296
    • Kim, H.1    Chung, H.2    Kim, H.J.3
  • 37
    • 0043170868 scopus 로고    scopus 로고
    • Id-1 expression promotes cell survival through activation of NF-κB signalling pathway in prostate cancer cells
    • DOI 10.1038/sj.onc.1206693
    • Ling MT, Wang X, Ouyang XS et al. Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells. Oncogene 2003; 22: 4498-4508. (Pubitemid 36920693)
    • (2003) Oncogene , vol.22 , Issue.29 , pp. 4498-4508
    • Ling, M.-T.1    Wang, X.2    Ouyang, X.-S.3    Xu, K.4    Tsao, S.-W.5    Wong, Y.-C.6
  • 38
    • 33847304015 scopus 로고    scopus 로고
    • Id1 induces the proliferation of cochlear sensory epithelial cells via the nuclear factor-kappaB/cyclin D1 pathway in vitro
    • Ozeki M, Hamajima Y, Feng L et al. Id1 induces the proliferation of cochlear sensory epithelial cells via the nuclear factor-kappaB/cyclin D1 pathway in vitro. J Neurosci Res 2007; 85: 515-524.
    • (2007) J Neurosci Res , vol.85 , pp. 515-524
    • Ozeki, M.1    Hamajima, Y.2    Feng, L.3
  • 39
    • 33845925582 scopus 로고    scopus 로고
    • Id1 potentiates NF-κB activation upon T cell receptor signaling
    • DOI 10.1074/jbc.M608078200
    • Yang Y, Liou HC, Sun XH. Id1 potentiates NF-kappaB activation upon T cell receptor signaling. J Biol Chem 2006; 281: 34989-34996. (Pubitemid 46036538)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.46 , pp. 34989-34996
    • Yang, Y.1    Liou, H.-C.2    Sun, X.-H.3
  • 40
    • 0030475524 scopus 로고    scopus 로고
    • In vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat
    • Liu Y, Tolbert EM, Sun AM et al. In vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat. Am J Physiol Renal Physiol 1996; 271: F1202-F1210.
    • (1996) Am J Physiol Renal Physiol , vol.271
    • Liu, Y.1    Tolbert, E.M.2    Sun, A.M.3
  • 41
    • 79952080210 scopus 로고    scopus 로고
    • PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression
    • Wang D, Li Y, Wu C et al. PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression. PLoS One 2011; 6: e17048.
    • (2011) PLoS One , vol.6
    • Wang, D.1    Li, Y.2    Wu, C.3
  • 42
    • 0036854980 scopus 로고    scopus 로고
    • Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy
    • DOI 10.1172/JCI200216219
    • Yang J, Shultz RW, Mars WM et al. Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy. J Clin Invest 2002; 110: 1525-1538. (Pubitemid 35396923)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.10 , pp. 1525-1538
    • Yang, J.1    Shultz, R.W.2    Mars, W.M.3    Wegner, R.E.4    Li, Y.5    Dai, C.6    Nejak, K.7    Liu, Y.8
  • 43
    • 2542433088 scopus 로고    scopus 로고
    • Hepatocyte growth factor antagonizes the profibrotic action of TGF-β1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF
    • DOI 10.1097/01.ASN.0000130568.53923.FD
    • Dai C, Liu Y. Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF. J Am Soc Nephrol 2004; 15: 1402-1412. (Pubitemid 38679665)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.6 , pp. 1402-1412
    • Dai, C.1    Liu, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.