메뉴 건너뛰기




Volumn 11, Issue 11, 2015, Pages 681-686

The past 10 years-new hormones, new functions, new endocrine organs

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 23; HORMONE; IRISIN; LEPTIN; MYOSTATIN; OSTEOCALCIN; SOMATOMEDIN;

EID: 84945473213     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2015.142     Document Type: Review
Times cited : (14)

References (69)
  • 1
    • 84886305502 scopus 로고    scopus 로고
    • The osteocyte: An endocrine cell and more
    • Dallas, S. L., Prideaux, M. & Bonewald, L. F. The osteocyte: an endocrine cell and more. Endocr. Rev. 34, 658-690 (2013).
    • (2013) Endocr. Rev. , vol.34 , pp. 658-690
    • Dallas, S.L.1    Prideaux, M.2    Bonewald, L.F.3
  • 2
    • 53849136271 scopus 로고    scopus 로고
    • Vitamin D and human health: Lessons from Vitamin D receptor null mice
    • Bouillon, R. et al. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr. Rev. 29, 726-776 (2008).
    • (2008) Endocr. Rev. , vol.29 , pp. 726-776
    • Bouillon, R.1
  • 3
    • 84859956031 scopus 로고    scopus 로고
    • Skeletal secretion of FGF-23 regulates phosphate and Vitamin D metabolism
    • Quarles, L. D. Skeletal secretion of FGF-23 regulates phosphate and vitamin D metabolism. Nat. Rev. Endocrinol. 8, 276-286 (2012).
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 276-286
    • Quarles, L.D.1
  • 4
    • 84864339688 scopus 로고    scopus 로고
    • The role of FGF23 in CKD-with or without Kloth
    • Komaba, H. & Fukagawa, M. The role of FGF23 in CKD-with or without Kloth. Nat. Rev. Nephrol. 8, 484-490 (2012).
    • (2012) Nat. Rev. Nephrol. , vol.8 , pp. 484-490
    • Komaba, H.1    Fukagawa, M.2
  • 5
    • 84923114846 scopus 로고    scopus 로고
    • Anabolic bone therapies in 2014: New bone-forming treatments for osteoporosis
    • Papapoulos, S. E. Anabolic bone therapies in 2014: new bone-forming treatments for osteoporosis. Nat. Rev. Endocrinol. 11, 69-70 (2015).
    • (2015) Nat. Rev. Endocrinol. , vol.11 , pp. 69-70
    • Papapoulos, S.E.1
  • 6
    • 84855987634 scopus 로고    scopus 로고
    • The contribution of bone to whole-organism physiology
    • Karsenty, G. & Ferron, M. The contribution of bone to whole-organism physiology. Nature 481, 314-320 (2012).
    • (2012) Nature , vol.481 , pp. 314-320
    • Karsenty, G.1    Ferron, M.2
  • 7
    • 84899139279 scopus 로고    scopus 로고
    • Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis
    • Riddle, R. C. et al. Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis. Mol. Cell. Biol. 34, 1850-1862 (2014).
    • (2014) Mol. Cell. Biol. , vol.34 , pp. 1850-1862
    • Riddle, R.C.1
  • 8
    • 34547690686 scopus 로고    scopus 로고
    • Endocrine regulation of energy metabolism by the skeleton
    • Lee, N. K. et al. Endocrine regulation of energy metabolism by the skeleton. Cell 130, 456-469 (2007).
    • (2007) Cell , vol.130 , pp. 456-469
    • Lee, N.K.1
  • 9
    • 79952289069 scopus 로고    scopus 로고
    • Endocrine regulation of male fertility by the skeleton
    • Oury, F. et al. Endocrine regulation of male fertility by the skeleton. Cell 144, 796-809 (2011).
    • (2011) Cell , vol.144 , pp. 796-809
    • Oury, F.1
  • 10
    • 84961328603 scopus 로고    scopus 로고
    • Osteoimmunology in 2014: Two-faced immunology-from osteogenesis to bone resorption
    • Takayanagi, H. Osteoimmunology in 2014: two-faced immunology-from osteogenesis to bone resorption. Nat. Rev. Rheumatol. 11, 74-76 (2015).
    • (2015) Nat. Rev. Rheumatol. , vol.11 , pp. 74-76
    • Takayanagi, H.1
  • 11
    • 84878240625 scopus 로고    scopus 로고
    • Banting Lecture 2012: Regulation of adipogenesis: Toward new therapeutics for metabolic disease
    • Spiegelman, B. M. Banting Lecture 2012: regulation of adipogenesis: toward new therapeutics for metabolic disease. Diabetes 62, 1774-1782 (2013).
    • (2013) Diabetes , vol.62 , pp. 1774-1782
    • Spiegelman, B.M.1
  • 12
    • 84864283300 scopus 로고    scopus 로고
    • Exercise and obesity: Skeletal muscle as a secretory organ
    • Pedersen, B. K. & Febbraio, M. A. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat. Rev. Endocrinol. 8, 457-465 (2012).
    • (2012) Nat. Rev. Endocrinol. , vol.8 , pp. 457-465
    • Pedersen, B.K.1    Muscles, A.F.M.2
  • 13
    • 84892999166 scopus 로고    scopus 로고
    • Vitamin D and energy homeostasis: Of mice and men
    • Bouillon, R. et al. Vitamin D and energy homeostasis: of mice and men. Nat. Rev. Endocrinol. 10, 79-87 (2014).
    • (2014) Nat. Rev. Endocrinol. , vol.10 , pp. 79-87
    • Bouillon, R.1
  • 14
    • 84945467610 scopus 로고    scopus 로고
    • Ch. 39 (eds Melmed, S. et al.) (Elsevier Saunders
    • th edn Ch. 39 (eds Melmed, S. et al.) 1697-1718 (Elsevier Saunders, 2012).
    • (2012) th Edn , pp. 1697-1718
    • Vella, A.1    Drucker, D.2
  • 15
    • 0012664686 scopus 로고
    • Chemical determination of polypeptide hormones
    • Tatemoto, K. & Mutt, V. Chemical determination of polypeptide hormones. Proc. Natl Acad. Sci. USA 75, 4115-4119 (1978).
    • (1978) Proc. Natl Acad. Sci. USA , vol.75 , pp. 4115-4119
    • Tatemoto, K.1    Mutt, V.2
  • 16
    • 0020535282 scopus 로고
    • Exon duplication and divergence in the human preproglucagon gene
    • Bell, G. I., Sanchez-Pescador, R., Laybourn, P. J. & Najarian, R. C. Exon duplication and divergence in the human preproglucagon gene. Nature 304, 368-371 (1983).
    • (1983) Nature , vol.304 , pp. 368-371
    • Bell, G.I.1    Sanchez-Pescador, R.2    Laybourn, P.J.3    Najarian, R.C.4
  • 17
    • 56449093424 scopus 로고    scopus 로고
    • Glucose sensing in L cells: A primary cell study
    • Reimann, F. et al. Glucose sensing in L cells: a primary cell study. Cell Metab. 8, 532-539 (2008).
    • (2008) Cell Metab. , vol.8 , pp. 532-539
    • Reimann, F.1
  • 18
    • 84862743498 scopus 로고    scopus 로고
    • Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
    • Habib, A. M. et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology 153, 3054-3065 (2012).
    • (2012) Endocrinology , vol.153 , pp. 3054-3065
    • Habib, A.M.1
  • 20
    • 84878808238 scopus 로고    scopus 로고
    • Pharmacology physiology and mechanisms of incretin hormone action
    • Campbell, J. E. & Drucker, D. J. Pharmacology physiology and mechanisms of incretin hormone action. Cell Metab. 17, 819-837 (2013).
    • (2013) Cell Metab. , vol.17 , pp. 819-837
    • Campbell, J.E.1    Drucker, D.J.2
  • 21
    • 84894207845 scopus 로고    scopus 로고
    • Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2
    • Drucker, D. J. & Yusta, B. Physiology and pharmacology of the enteroendocrine hormone glucagon-like peptide-2. Annu. Rev. Physiol. 76, 561-583 (2014).
    • (2014) Annu. Rev. Physiol. , vol.76 , pp. 561-583
    • Drucker, D.J.1    Yusta, B.2
  • 22
    • 84925282923 scopus 로고    scopus 로고
    • A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
    • Finan, B. et al. A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents. Nat. Med. 21, 27-36 (2015).
    • (2015) Nat. Med. , vol.21 , pp. 27-36
    • Finan, B.1
  • 23
    • 84879414291 scopus 로고    scopus 로고
    • Emerging combinatorial hormone therapies for the treatment of obesity and T2DM
    • Sadry, S. A. & Drucker, D. J. Emerging combinatorial hormone therapies for the treatment of obesity and T2DM. Nat. Rev. Endocrinol. 9, 425-433 (2013).
    • (2013) Nat. Rev. Endocrinol. , vol.9 , pp. 425-433
    • Sadry, S.A.1    Drucker, D.J.2
  • 24
    • 65249099918 scopus 로고    scopus 로고
    • Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability
    • Cani, P. D. et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut 58, 1091-1103 (2009).
    • (2009) Gut , vol.58 , pp. 1091-1103
    • Cani, P.D.1
  • 25
    • 84912137874 scopus 로고    scopus 로고
    • Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells
    • Chimerel, C. et al. Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells. Cell Rep. 9, 1202-1208 (2014).
    • (2014) Cell Rep. , vol.9 , pp. 1202-1208
    • Chimerel, C.1
  • 28
    • 84927172678 scopus 로고    scopus 로고
    • Adipokines, vascular wall, and cardiovascular disease: A focused overview of the role of adipokines in the pathophysiology of cardiovascular disease
    • Maresca, F. et al. Adipokines, vascular wall, and cardiovascular disease: a focused overview of the role of adipokines in the pathophysiology of cardiovascular disease. Angiology 66, 8-24 (2015).
    • (2015) Angiology , vol.66 , pp. 8-24
    • Maresca, F.1
  • 30
    • 84860439210 scopus 로고    scopus 로고
    • Interplay between lipids and branched-chain amino acids in development of insulin resistance
    • Newgard, C. B. Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell Metab. 15, 606-614 (2012).
    • (2012) Cell Metab. , vol.15 , pp. 606-614
    • Newgard, C.B.1
  • 31
    • 84876575039 scopus 로고    scopus 로고
    • Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance
    • Ferrannini, E. et al. Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance. Diabetes 62, 1730-1737 (2013).
    • (2013) Diabetes , vol.62 , pp. 1730-1737
    • Ferrannini, E.1
  • 32
    • 84894478069 scopus 로고    scopus 로고
    • Insulin resistance alters islet morphology in nondiabetic humans
    • Mezza, T. et al. Insulin resistance alters islet morphology in nondiabetic humans. Diabetes 63, 994-1007 (2014).
    • (2014) Diabetes , vol.63 , pp. 994-1007
    • Mezza, T.1
  • 33
    • 84866389264 scopus 로고    scopus 로고
    • Pancreatic β-cell dedifferentiation as a mechanism of diabetic β-cell failure
    • Talchai, C., Xuan, S., Lin, H. V., Sussel, L. & Accili, D. Pancreatic β-cell dedifferentiation as a mechanism of diabetic β-cell failure. Cell 150, 1223-1234 (2012).
    • (2012) Cell , vol.150 , pp. 1223-1234
    • Talchai, C.1    Xuan, S.2    Lin, H.V.3    Sussel, L.4    Accili, D.5
  • 34
    • 77954323314 scopus 로고    scopus 로고
    • The stunned β cell: A brief history
    • Ferrannini, E. The stunned β cell: a brief history. Cell Metab. 11, 349-352 (2010).
    • (2010) Cell Metab. , vol.11 , pp. 349-352
    • Ferrannini, E.1
  • 35
    • 84885047941 scopus 로고    scopus 로고
    • Lipotoxicity disrupts incretin-regulated human β-cell connectivity
    • Hodson, D. J. et al. Lipotoxicity disrupts incretin-regulated human β-cell connectivity. J. Clin. Invest. 123, 4182-4194 (2013).
    • (2013) J. Clin. Invest. , vol.123 , pp. 4182-4194
    • Hodson, D.J.1
  • 36
    • 78049308422 scopus 로고    scopus 로고
    • Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study
    • Preis, S. R. et al. Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart study. Obesity, 11, 2191-2198 (2010).
    • (2010) Obesity , vol.11 , pp. 2191-2198
    • Preis, S.R.1
  • 37
    • 0032477331 scopus 로고    scopus 로고
    • Abdominal obesity and coronary heart disease in women
    • Rexrode, K. M. et al. Abdominal obesity and coronary heart disease in women. JAMA 280, 1843-1848 (1998).
    • (1998) JAMA , vol.280 , pp. 1843-1848
    • Rexrode, K.M.1
  • 38
    • 84887018758 scopus 로고    scopus 로고
    • Normal weight obesity and mortality in United States subjects 60 years of age (from the Third National Health and Nutrition Examination Survey)
    • Batsis, J. A. et al. Normal weight obesity and mortality in United States subjects 60 years of age (from the Third National Health and Nutrition Examination Survey). Am. J. Cardiol. 112, 1592-1598 (2013).
    • (2013) Am. J. Cardiol. , vol.112 , pp. 1592-1598
    • Batsis, J.A.1
  • 39
    • 84866073021 scopus 로고    scopus 로고
    • The ratio of visceral to subcutaneous fat, a metric of body fat distribution is a unique correlate of cardiometabolic risk
    • Kaess, B. M. The ratio of visceral to subcutaneous fat, a metric of body fat distribution is a unique correlate of cardiometabolic risk. Diabetologia 10, 2622-2630 (2012).
    • (2012) Diabetologia , vol.10 , pp. 2622-2630
    • Kaess, B.M.1
  • 40
    • 77956576248 scopus 로고    scopus 로고
    • Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: A pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data
    • Falutz, J. et al. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data. J. Clin. Endocrinol. Metab. 95, 4291-4304 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 4291-4304
    • Falutz, J.1
  • 41
    • 36849058739 scopus 로고    scopus 로고
    • Metabolic effects of a growth hormone-releasing factor in patients with HIV
    • Falutz, J. et al. Metabolic effects of a growth hormone-releasing factor in patients with HIV. N. Engl. J. Med. 357, 2359-2370 (2007).
    • (2007) N. Engl. J. Med. , vol.357 , pp. 2359-2370
    • Falutz, J.1
  • 42
    • 57349141683 scopus 로고    scopus 로고
    • The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men
    • Makimura, H., Stanley, T., Mun, D., You, S. M. & Grinspoon, S. The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men. J. Clin. Endocrinol. Metab. 93, 4254-4260 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 4254-4260
    • Makimura, H.1    Stanley, T.2    Mun, D.3    You, S.M.4    Grinspoon, S.5
  • 43
    • 14044276421 scopus 로고    scopus 로고
    • Truncal adiposity, relative growth hormone deficiency, and cardiovascular risk
    • Miller, K. K. et al. Truncal adiposity, relative growth hormone deficiency, and cardiovascular risk. J. Clin. Endocrinol. Metab. 90, 768-774 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 768-774
    • Miller, K.K.1
  • 44
    • 73249120020 scopus 로고    scopus 로고
    • Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity
    • Makimura, H. et al. Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity. J. Clin. Endocrinol. Metab. 94, 5131-5138 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 5131-5138
    • Makimura, H.1
  • 45
    • 0942287339 scopus 로고    scopus 로고
    • Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy
    • Koutkia, P., Meininger, G., Canavan, B., Breu, J. & Grinspoon, S. Metabolic regulation of growth hormone by free fatty acids, somatostatin, and ghrelin in HIV-lipodystrophy. Am. J. Physiol. Endocrinol. Metab. 286, E296-E303 (2004).
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.286 , pp. E296-E303
    • Koutkia, P.1    Meininger, G.2    Canavan, B.3    Breu, J.4    Grinspoon, S.5
  • 46
    • 0029913476 scopus 로고    scopus 로고
    • Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli
    • Peino, R. et al. Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli. J. Clin. Endocrinol. Metab. 81, 909-913 (1996).
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 909-913
    • Peino, R.1
  • 47
    • 0035090230 scopus 로고    scopus 로고
    • Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy
    • Reitschel, P. et al. Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy. J. Clin. Endcocrinol. Metab. 86, 504-510 (2001).
    • (2001) J. Clin. Endcocrinol. Metab. , vol.86 , pp. 504-510
    • Reitschel, P.1
  • 48
    • 84904543851 scopus 로고    scopus 로고
    • Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: A randomized clinical trial
    • Stanley, T. L. et al. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial. JAMA 312, 380-389 (2014).
    • (2014) JAMA , vol.312 , pp. 380-389
    • Stanley, T.L.1
  • 50
    • 0141737573 scopus 로고    scopus 로고
    • Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
    • Ducy, P. et al. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100, 197-207 (2000).
    • (2000) Cell , vol.100 , pp. 197-207
    • Ducy, P.1
  • 51
    • 84877579844 scopus 로고    scopus 로고
    • WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation
    • Esen, E. et al. WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation. Cell Metab. 17, 745-755 (2013).
    • (2013) Cell Metab. , vol.17 , pp. 745-755
    • Esen, E.1
  • 52
    • 84907483743 scopus 로고    scopus 로고
    • A review of osteocyte function and the emerging importance of sclerostin
    • Compton, J. & Lee, F. A review of osteocyte function and the emerging importance of sclerostin. J. Bone Joint Surg. Am. 96, 1659-1668 (2014).
    • (2014) J. Bone Joint Surg. Am. , vol.96 , pp. 1659-1668
    • Compton, J.1    Lee, F.2
  • 53
    • 84878507158 scopus 로고    scopus 로고
    • FGF23 production by osteocytes
    • Bonewald, L. F. & Wacker, M. J. FGF23 production by osteocytes. Pediatr. Nephrol. 28, 563-568 (2013).
    • (2013) Pediatr. Nephrol. , vol.28 , pp. 563-568
    • Bonewald, L.F.1    Wacker, M.J.2
  • 54
    • 80053938104 scopus 로고    scopus 로고
    • Evidence for osteocyte regulation of bone homeostasis through RANKL expression
    • Nakashima, T. et al. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat. Med. 17, 1231-1234 (2011).
    • (2011) Nat. Med. , vol.17 , pp. 1231-1234
    • Nakashima, T.1
  • 55
    • 77955035304 scopus 로고    scopus 로고
    • Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism
    • Ferron, M. et al. Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell 142, 296-308 (2010).
    • (2010) Cell , vol.142 , pp. 296-308
    • Ferron, M.1
  • 57
    • 64349090658 scopus 로고    scopus 로고
    • Fat, and body composition: Evolving concepts in the pathogenesis of osteoporosis
    • Rosen, C. J. & Klibanski. A. Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis. Am. J. Med. 122, 409-414 (2009).
    • (2009) Am. J. Med. , vol.122 , pp. 409-414
    • Rosen, C.J.1    Bone, K.A.2
  • 58
    • 84899448778 scopus 로고    scopus 로고
    • Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass
    • Guntur, A. R., Le, P. T., Farber, C. R. & Rosen, C. J. Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass. Endocrinology 155, 1589-1595 (2014).
    • (2014) Endocrinology , vol.155 , pp. 1589-1595
    • Guntur, A.R.1    Le, P.T.2    Farber, C.R.3    Rosen, C.J.4
  • 59
    • 84917736109 scopus 로고    scopus 로고
    • Aerobic glycolysis in osteoblasts
    • Esen, E. & Long, F. Aerobic glycolysis in osteoblasts. Curr. Osteoporos. Rep. 12, 433-438 (2014).
    • (2014) Curr. Osteoporos. Rep. , vol.12 , pp. 433-438
    • Esen, E.1    Long, F.2
  • 60
    • 84905817103 scopus 로고    scopus 로고
    • Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction
    • Cawthorn, W. P. et al. Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction. Cell Metab. 20, 368-375 (2014).
    • (2014) Cell Metab. , vol.20 , pp. 368-375
    • Cawthorn, W.P.1
  • 62
    • 84895832615 scopus 로고    scopus 로고
    • Global estimates of diabetes prevalence in adults for 2013 and projections for 2035 for the IDF Diabetes Atlas
    • Guariguata, L. et al. Global estimates of diabetes prevalence in adults for 2013 and projections for 2035 for the IDF Diabetes Atlas. Diabetes Res. Clin. Pract. 103, 137-149 (2014).
    • (2014) Diabetes Res. Clin. Pract. , vol.103 , pp. 137-149
    • Guariguata, L.1
  • 63
    • 84896491806 scopus 로고    scopus 로고
    • The many faces of diabetes: A disease with increasing heterogeneity
    • Tuomi, T. et al. The many faces of diabetes: a disease with increasing heterogeneity. Lancet 383, 1084-1094 (2014).
    • (2014) Lancet , vol.383 , pp. 1084-1094
    • Tuomi, T.1
  • 64
    • 84896495719 scopus 로고    scopus 로고
    • Pathophysiology and treatment of type 2 diabetes
    • Kahn, S. E., Cooper, M. E. & Del Prato, S. Pathophysiology and treatment of type 2 diabetes. Lancet 383, 1068-1083 (2014).
    • (2014) Lancet , vol.383 , pp. 1068-1083
    • Kahn, S.E.1    Cooper, M.E.2    Del Prato, S.3
  • 65
    • 41149084500 scopus 로고    scopus 로고
    • Clinical implications of a molecular genetic classification of monogenic β-cell diabetes
    • Murphy, R., Ellard, S. & Hattersley, A. T. Clinical implications of a molecular genetic classification of monogenic β-cell diabetes. Nat. Clin. Pract. Endocrinol. Metab. 4, 200-213 (2008).
    • (2008) Nat. Clin. Pract. Endocrinol. Metab. , vol.4 , pp. 200-213
    • Murphy, R.1    Ellard, S.2    Hattersley, A.T.3
  • 66
    • 84876260798 scopus 로고    scopus 로고
    • A gene of rare effect
    • Hall, S. S. A gene of rare effect. Nature 496, 152-155 (2013).
    • (2013) Nature , vol.496 , pp. 152-155
    • Hall, S.S.1
  • 67
    • 84860213446 scopus 로고    scopus 로고
    • Surgery or medical therapy for obese patients with type 2 diabetes?
    • Zimmet, P. & Alberti, K. G. Surgery or medical therapy for obese patients with type 2 diabetes? N. Engl. J. Med. 366, 1635-1636 (2012).
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1635-1636
    • Zimmet, P.1    Alberti, K.G.2
  • 69
    • 84893444129 scopus 로고    scopus 로고
    • Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides
    • Adamovich, Y. Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides. Cell Metab. 19, 319-330 (2014).
    • (2014) Cell Metab. , vol.19 , pp. 319-330
    • Adamovich, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.