Squaramide-Catalyzed Synthesis of Enantioenriched Spirocyclic Oxindoles via Ketimine Intermediates with Multiple Active Sites

Angewandte Chemie - International Edition

Volumn 54, Issue 45, 2015, Pages 13253-13257

  Sun, Qiang Sheng ^a   Zhu, Hua ^a   Chen, Yong Jian ^a   Yang, Xiao Di ^a   Sun, Xing Wen ^a   Lin, Guo Qiang ^b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

asymmetric synthesis; ketimines; Mannich reactions; Michael additions; nitrogen heterocycles; organocatalysis

Indexed keywords

ADDITION REACTIONS; SYNTHESIS (CHEMICAL);

ASYMMETRIC SYNTHESIS; KETIMINES; MANNICH REACTIONS; MICHAEL ADDITIONS; NITROGEN HETEROCYCLES; ORGANOCATALYSIS;

CATALYSIS;

IMINE; INDOLE DERIVATIVE; KETIMINE; NITRILE; QUININE; SPIRO COMPOUND; SQUARAMIDE;

ANALOGS AND DERIVATIVES; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; CATALYTIC DOMAIN; IMINES; INDOLES; MOLECULAR STRUCTURE; NITRILES; QUININE; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 84945288461     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201506206     Document Type: Article

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