메뉴 건너뛰기




Volumn 268, Issue 1, 2015, Pages 160-174

The many faces of FcγRI: Implications for therapeutic antibody function

Author keywords

Fc RI; Immune complexes; Therapeutic antibodies

Indexed keywords

CD64 ANTIGEN; CYTOKINE; FC RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 10; MONOCLONAL ANTIBODY; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; LIGAND; PROTEIN BINDING; TUMOR NECROSIS FACTOR ALPHA;

EID: 84945248970     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12334     Document Type: Review
Times cited : (44)

References (137)
  • 1
    • 84945275929 scopus 로고    scopus 로고
    • Regulatory considerations in the development of monoclonal antibodies for diagnosis and therapy
    • Wiley-VCH Verlag GmbH & Co.: KGaA, Weinheim, Germany
    • Shapiro MA, Swann PG, Ricci MS. Regulatory considerations in the development of monoclonal antibodies for diagnosis and therapy. Handbook of Therapeutic Antibodies. Wiley-VCH Verlag GmbH & Co.: KGaA, Weinheim, Germany, 2007;1231-1262.
    • (2007) Handbook of Therapeutic Antibodies , pp. 1231-1262
    • Shapiro, M.A.1    Swann, P.G.2    Ricci, M.S.3
  • 2
    • 64249112661 scopus 로고    scopus 로고
    • Current constructs and targets in clinical development for antibody-based cancer therapy
    • Deckert PM. Current constructs and targets in clinical development for antibody-based cancer therapy. Curr Drug Targets 2009;10:158-175.
    • (2009) Curr Drug Targets , vol.10 , pp. 158-175
    • Deckert, P.M.1
  • 3
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn F, Ravetch JV. Fcgamma receptors as regulators of immune responses. Nat Rev Immunol 2008;8:34-47.
    • (2008) Nat Rev Immunol , vol.8 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 4
    • 22544487815 scopus 로고    scopus 로고
    • FcgammaRIV: a novel FcR with distinct IgG subclass specificity
    • Nimmerjahn F, Bruhns P, Horiuchi K, Ravetch JV. FcgammaRIV: a novel FcR with distinct IgG subclass specificity. Immunity 2005;23:41-51.
    • (2005) Immunity , vol.23 , pp. 41-51
    • Nimmerjahn, F.1    Bruhns, P.2    Horiuchi, K.3    Ravetch, J.V.4
  • 5
    • 0031646641 scopus 로고    scopus 로고
    • Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts
    • Ernst LK, Duchemin AM, Miller KL, Anderson CL. Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts. Mol Immunol 1998;35:943-954.
    • (1998) Mol Immunol , vol.35 , pp. 943-954
    • Ernst, L.K.1    Duchemin, A.M.2    Miller, K.L.3    Anderson, C.L.4
  • 7
    • 0038532175 scopus 로고    scopus 로고
    • FcgammaR polymorphisms: implications for function, disease susceptibility and immunotherapy
    • van Sorge NM, van der Pol WL, van de Winkel JG. FcgammaR polymorphisms: implications for function, disease susceptibility and immunotherapy. Tissue Antigens 2003;61:189-202.
    • (2003) Tissue Antigens , vol.61 , pp. 189-202
    • van Sorge, N.M.1    van der Pol, W.L.2    van de Winkel, J.G.3
  • 8
    • 0031674586 scopus 로고    scopus 로고
    • The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a
    • Hulett MD, Hogarth PM. The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a. Mol Immunol 1998;35:989-996.
    • (1998) Mol Immunol , vol.35 , pp. 989-996
    • Hulett, M.D.1    Hogarth, P.M.2
  • 9
    • 81755172412 scopus 로고    scopus 로고
    • Crystal structure of Fcgamma receptor I and its implication in high affinity gamma-immunoglobulin binding
    • Lu J, Ellsworth JL, Hamacher N, Oak SW, Sun PD. Crystal structure of Fcgamma receptor I and its implication in high affinity gamma-immunoglobulin binding. J Biol Chem 2011;286:40608-40613.
    • (2011) J Biol Chem , vol.286 , pp. 40608-40613
    • Lu, J.1    Ellsworth, J.L.2    Hamacher, N.3    Oak, S.W.4    Sun, P.D.5
  • 10
    • 84922360962 scopus 로고    scopus 로고
    • Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding
    • Lu J, Chu J, Zou Z, Hamacher NB, Rixon MW, Sun PD. Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding. Proc Natl Acad Sci USA 2015;112:833-838.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 833-838
    • Lu, J.1    Chu, J.2    Zou, Z.3    Hamacher, N.B.4    Rixon, M.W.5    Sun, P.D.6
  • 11
    • 84928776106 scopus 로고    scopus 로고
    • Structural basis for binding of human IgG1 to its high-affinity human receptor FcgammaRI
    • Kiyoshi M, et al. Structural basis for binding of human IgG1 to its high-affinity human receptor FcgammaRI. Nat Commun 2015;6:6866.
    • (2015) Nat Commun , vol.6 , pp. 6866
    • Kiyoshi, M.1
  • 12
    • 0029875464 scopus 로고    scopus 로고
    • FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo
    • vanVugt MJ, et al. FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. Blood 1996;87:3593-3599.
    • (1996) Blood , vol.87 , pp. 3593-3599
    • vanVugt, M.J.1
  • 13
    • 0026540751 scopus 로고
    • Multichain immune recognition receptors: similarities in structure and signaling pathways
    • Keegan AD, Paul WE. Multichain immune recognition receptors: similarities in structure and signaling pathways. Immunol Today 1992;13:63-68.
    • (1992) Immunol Today , vol.13 , pp. 63-68
    • Keegan, A.D.1    Paul, W.E.2
  • 14
    • 0028042424 scopus 로고
    • FcR gamma chain deletion results in pleiotrophic effector cell defects
    • Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV. FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 1994;76:519-529.
    • (1994) Cell , vol.76 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 15
    • 0030929805 scopus 로고    scopus 로고
    • Fc receptor biology
    • Daeron M. Fc receptor biology. Annu Rev Immunol 1997;15:203-234.
    • (1997) Annu Rev Immunol , vol.15 , pp. 203-234
    • Daeron, M.1
  • 16
    • 0024531803 scopus 로고
    • Isolation and expression of functional high-affinity Fc receptor complementary DNAs
    • Allen JM, Seed B. Isolation and expression of functional high-affinity Fc receptor complementary DNAs. Science 1989;243:378-381.
    • (1989) Science , vol.243 , pp. 378-381
    • Allen, J.M.1    Seed, B.2
  • 17
    • 0036009179 scopus 로고    scopus 로고
    • FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses
    • Barnes N, Gavin AL, Tan PS, Mottram P, Koentgen F, Hogarth PM. FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 2002;16:379-389.
    • (2002) Immunity , vol.16 , pp. 379-389
    • Barnes, N.1    Gavin, A.L.2    Tan, P.S.3    Mottram, P.4    Koentgen, F.5    Hogarth, P.M.6
  • 18
    • 0030818074 scopus 로고    scopus 로고
    • Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects
    • Schiff DE, Rae J, Martin TR, Davis BH, Curnutte JT. Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects. Blood 1997;90:3187-3194.
    • (1997) Blood , vol.90 , pp. 3187-3194
    • Schiff, D.E.1    Rae, J.2    Martin, T.R.3    Davis, B.H.4    Curnutte, J.T.5
  • 19
    • 48949118204 scopus 로고    scopus 로고
    • Neutrophil and monocyte CD64 and CD163 expression in critically ill neonates and children with sepsis: comparison of fluorescence intensities and calculated indexes
    • Groselj-Grenc M, Ihan A, Derganc M. Neutrophil and monocyte CD64 and CD163 expression in critically ill neonates and children with sepsis: comparison of fluorescence intensities and calculated indexes. Mediators Inflamm 2008;2008:202646.
    • (2008) Mediators Inflamm , vol.2008 , pp. 202646
    • Groselj-Grenc, M.1    Ihan, A.2    Derganc, M.3
  • 20
    • 0026065071 scopus 로고
    • Fc gamma-receptors on Langerhans' cells and keratinocytes in suspension from normal skin characterized using soluble immune complexes and monoclonal antibodies
    • Tigalonowa M, Bjerke JR, Matre R. Fc gamma-receptors on Langerhans' cells and keratinocytes in suspension from normal skin characterized using soluble immune complexes and monoclonal antibodies. Acta Derm Venereol 1991;71:99-103.
    • (1991) Acta Derm Venereol , vol.71 , pp. 99-103
    • Tigalonowa, M.1    Bjerke, J.R.2    Matre, R.3
  • 21
    • 0017160140 scopus 로고
    • Appearance of IgG (Fc) receptor(s) on cultured human fibroblasts infected with human cytomegalovirus
    • Rahman AA, Teschner M, Sethi KK, Brandis H. Appearance of IgG (Fc) receptor(s) on cultured human fibroblasts infected with human cytomegalovirus. J Immunol 1976;117:253-258.
    • (1976) J Immunol , vol.117 , pp. 253-258
    • Rahman, A.A.1    Teschner, M.2    Sethi, K.K.3    Brandis, H.4
  • 22
    • 84865293881 scopus 로고    scopus 로고
    • Fc gamma receptor CD64 modulates the inhibitory activity of infliximab
    • Wojtal KA, et al. Fc gamma receptor CD64 modulates the inhibitory activity of infliximab. PLoS ONE 2012;7:e43361.
    • (2012) PLoS ONE , vol.7 , pp. e43361
    • Wojtal, K.A.1
  • 23
    • 0031595604 scopus 로고    scopus 로고
    • Detection of Fcgamma receptors on human endothelial cells stimulated with cytokines tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma)
    • Pan LF, Kreisle RA, Shi YD. Detection of Fcgamma receptors on human endothelial cells stimulated with cytokines tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma). Clin Exp Immunol 1998;112:533-538.
    • (1998) Clin Exp Immunol , vol.112 , pp. 533-538
    • Pan, L.F.1    Kreisle, R.A.2    Shi, Y.D.3
  • 24
    • 79952162741 scopus 로고    scopus 로고
    • Functional expression of IgG-Fc receptors in human airway smooth muscle cells
    • Xia YC, et al. Functional expression of IgG-Fc receptors in human airway smooth muscle cells. Am J Respir Cell Mol Biol 2011;44:665-672.
    • (2011) Am J Respir Cell Mol Biol , vol.44 , pp. 665-672
    • Xia, Y.C.1
  • 25
    • 77956393132 scopus 로고    scopus 로고
    • Involvement of Fc receptors in disorders of the central nervous system
    • Okun E, Mattson MP, Arumugam TV. Involvement of Fc receptors in disorders of the central nervous system. NeuroMol Med 2010;12:164-178.
    • (2010) NeuroMol Med , vol.12 , pp. 164-178
    • Okun, E.1    Mattson, M.P.2    Arumugam, T.V.3
  • 26
    • 0020564130 scopus 로고
    • Immune interferon induces the receptor for monomeric IgG1 on human monocytic and myeloid cells
    • Perussia B, Dayton ET, Lazarus R, Fanning V, Trinchieri G. Immune interferon induces the receptor for monomeric IgG1 on human monocytic and myeloid cells. J Exp Med 1983;158:1092-1113.
    • (1983) J Exp Med , vol.158 , pp. 1092-1113
    • Perussia, B.1    Dayton, E.T.2    Lazarus, R.3    Fanning, V.4    Trinchieri, G.5
  • 27
    • 0020564534 scopus 로고
    • Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes
    • Guyre PM, Morganelli PM, Miller R. Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes. J Clin Invest 1983;72:393-397.
    • (1983) J Clin Invest , vol.72 , pp. 393-397
    • Guyre, P.M.1    Morganelli, P.M.2    Miller, R.3
  • 28
    • 0027057265 scopus 로고
    • IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10
    • te Velde AA, de Waal Malefijt R, Huijbens RJ, de Vries JE, Figdor CG. IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10. J Immunol 1992;149:4048-4052.
    • (1992) J Immunol , vol.149 , pp. 4048-4052
    • te Velde, A.A.1    de Waal Malefijt, R.2    Huijbens, R.J.3    de Vries, J.E.4    Figdor, C.G.5
  • 29
    • 0026000790 scopus 로고
    • Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor
    • Repp R, et al. Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor. Blood 1991;78:885-889.
    • (1991) Blood , vol.78 , pp. 885-889
    • Repp, R.1
  • 30
    • 0025361669 scopus 로고
    • IL-4 decreases Fc gamma R membrane expression and Fc gamma R-mediated cytotoxic activity of human monocytes
    • te Velde AA, Huijbens RJ, de Vries JE, Figdor CG. IL-4 decreases Fc gamma R membrane expression and Fc gamma R-mediated cytotoxic activity of human monocytes. J Immunol 1990;144:3046-3051.
    • (1990) J Immunol , vol.144 , pp. 3046-3051
    • te Velde, A.A.1    Huijbens, R.J.2    de Vries, J.E.3    Figdor, C.G.4
  • 31
    • 71549115144 scopus 로고    scopus 로고
    • CD64 index provides simple and predictive testing for detection and monitoring of sepsis and bacterial infection in hospital patients
    • Icardi M, Erickson Y, Kilborn S, Stewart B, Grief B, Scharnweber G. CD64 index provides simple and predictive testing for detection and monitoring of sepsis and bacterial infection in hospital patients. J Clin Microbiol 2009;47:3914-3919.
    • (2009) J Clin Microbiol , vol.47 , pp. 3914-3919
    • Icardi, M.1    Erickson, Y.2    Kilborn, S.3    Stewart, B.4    Grief, B.5    Scharnweber, G.6
  • 32
    • 70349478739 scopus 로고    scopus 로고
    • Neutrophil CD64: a diagnostic marker for infection and sepsis
    • Hoffmann JJ. Neutrophil CD64: a diagnostic marker for infection and sepsis. Clin Chem Lab Med 2009;47:903-916.
    • (2009) Clin Chem Lab Med , vol.47 , pp. 903-916
    • Hoffmann, J.J.1
  • 33
    • 84869224881 scopus 로고    scopus 로고
    • Neutrophil CD64 expression is elevated in acetaminophen-induced acute liver failure
    • author reply 9-60.
    • Abeles RD, et al. Neutrophil CD64 expression is elevated in acetaminophen-induced acute liver failure. Am J Respir Crit Care Med 2012;186:1058-1059; author reply 9-60.
    • (2012) Am J Respir Crit Care Med , vol.186 , pp. 1058-1059
    • Abeles, R.D.1
  • 34
    • 84903713683 scopus 로고    scopus 로고
    • CD64 expression is increased in patients with severe acute pancreatitis: clinical significance
    • Zhang H, et al. CD64 expression is increased in patients with severe acute pancreatitis: clinical significance. Gut Liv 2014;8:445-451.
    • (2014) Gut Liv , vol.8 , pp. 445-451
    • Zhang, H.1
  • 35
    • 84931843587 scopus 로고    scopus 로고
    • Neutrophil and monocyte Toll-like receptor 4, CD11b and reactive oxygen intermediates and neuroimaging outcomes in preterm infants
    • O'Hare FM, et al. Neutrophil and monocyte Toll-like receptor 4, CD11b and reactive oxygen intermediates and neuroimaging outcomes in preterm infants. Pediatr Res 2015;78:82-90.
    • (2015) Pediatr Res , vol.78 , pp. 82-90
    • O'Hare, F.M.1
  • 36
    • 55149094739 scopus 로고    scopus 로고
    • Interleukin-10: new perspectives on an old cytokine
    • Mosser DM, Zhang X. Interleukin-10: new perspectives on an old cytokine. Immunol Rev 2008;226:205-218.
    • (2008) Immunol Rev , vol.226 , pp. 205-218
    • Mosser, D.M.1    Zhang, X.2
  • 37
    • 0027492915 scopus 로고
    • Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10
    • de Waal Malefyt R, et al. Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10. J Immunol 1993;151:6370-6381.
    • (1993) J Immunol , vol.151 , pp. 6370-6381
    • de Waal Malefyt, R.1
  • 38
    • 0343618515 scopus 로고    scopus 로고
    • Cooperation among Stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes
    • Aittomaki S, Pesu M, Groner B, Janne OA, Palvimo JJ, Silvennoinen O. Cooperation among Stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes. J Immunol 2000;164:5689-5697.
    • (2000) J Immunol , vol.164 , pp. 5689-5697
    • Aittomaki, S.1    Pesu, M.2    Groner, B.3    Janne, O.A.4    Palvimo, J.J.5    Silvennoinen, O.6
  • 39
    • 78650043719 scopus 로고    scopus 로고
    • Cytokine-induced immune complex binding to the high-affinity IgG receptor, Fc gamma RI, in the presence of monomeric IgG
    • van der Poel CE, et al. Cytokine-induced immune complex binding to the high-affinity IgG receptor, Fc gamma RI, in the presence of monomeric IgG. Blood 2010;116:5327-5333.
    • (2010) Blood , vol.116 , pp. 5327-5333
    • van der Poel, C.E.1
  • 40
    • 84862495640 scopus 로고    scopus 로고
    • Properties of mouse and human IgG receptors and their contribution to disease models
    • Bruhns P. Properties of mouse and human IgG receptors and their contribution to disease models. Blood 2012;119:5640-5649.
    • (2012) Blood , vol.119 , pp. 5640-5649
    • Bruhns, P.1
  • 41
    • 65549114676 scopus 로고    scopus 로고
    • Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses
    • Bruhns P, et al. Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses. Blood 2009;113:3716-3725.
    • (2009) Blood , vol.113 , pp. 3716-3725
    • Bruhns, P.1
  • 42
    • 84875998684 scopus 로고    scopus 로고
    • Impact of immune complex size and glycosylation on IgG binding to human FcgammaRs
    • Lux A, Yu X, Scanlan CN, Nimmerjahn F. Impact of immune complex size and glycosylation on IgG binding to human FcgammaRs. J Immunol 2013;190:4315-4323.
    • (2013) J Immunol , vol.190 , pp. 4315-4323
    • Lux, A.1    Yu, X.2    Scanlan, C.N.3    Nimmerjahn, F.4
  • 43
    • 0032528045 scopus 로고    scopus 로고
    • Gain-of-function mutations in FcgammaRI of NOD mice: implications for the evolution of the Ig superfamily
    • Gavin AL, Tan PS, Hogarth PM. Gain-of-function mutations in FcgammaRI of NOD mice: implications for the evolution of the Ig superfamily. EMBO J 1998;17:3850-3857.
    • (1998) EMBO J , vol.17 , pp. 3850-3857
    • Gavin, A.L.1    Tan, P.S.2    Hogarth, P.M.3
  • 44
    • 0026592447 scopus 로고
    • Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene
    • Osman N, Kozak CA, McKenzie IF, Hogarth PM. Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene. J Immunol 1992;148:1570-1575.
    • (1992) J Immunol , vol.148 , pp. 1570-1575
    • Osman, N.1    Kozak, C.A.2    McKenzie, I.F.3    Hogarth, P.M.4
  • 45
    • 0025886261 scopus 로고
    • Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene
    • van de Winkel JG, Ernst LK, Anderson CL, Chiu IM. Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene. J Biol Chem 1991;266:13449-13455.
    • (1991) J Biol Chem , vol.266 , pp. 13449-13455
    • van de Winkel, J.G.1    Ernst, L.K.2    Anderson, C.L.3    Chiu, I.M.4
  • 46
    • 0016713311 scopus 로고
    • Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages
    • Unkeless JC, Eisen HN. Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages. J Exp Med 1975;142:1520-1533.
    • (1975) J Exp Med , vol.142 , pp. 1520-1533
    • Unkeless, J.C.1    Eisen, H.N.2
  • 47
    • 84871105419 scopus 로고    scopus 로고
    • Cutting edge: FcgammaRIII (CD16) and FcgammaRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma
    • Albanesi M, et al. Cutting edge: FcgammaRIII (CD16) and FcgammaRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma. J Immunol 2012;189:5513-5517.
    • (2012) J Immunol , vol.189 , pp. 5513-5517
    • Albanesi, M.1
  • 48
    • 84876463158 scopus 로고    scopus 로고
    • The high-affinity human IgG receptor Fc gamma RI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy
    • Mancardi DA, et al. The high-affinity human IgG receptor Fc gamma RI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy. Blood 2013;121:1563-1573.
    • (2013) Blood , vol.121 , pp. 1563-1573
    • Mancardi, D.A.1
  • 50
    • 57749172475 scopus 로고    scopus 로고
    • Structural recognition and functional activation of FcgammaR by innate pentraxins
    • Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD. Structural recognition and functional activation of FcgammaR by innate pentraxins. Nature 2008;456:989-992.
    • (2008) Nature , vol.456 , pp. 989-992
    • Lu, J.1    Marnell, L.L.2    Marjon, K.D.3    Mold, C.4    Du Clos, T.W.5    Sun, P.D.6
  • 51
    • 77952887713 scopus 로고    scopus 로고
    • The SYK tyrosine kinase: a crucial player in diverse biological functions
    • Mocsai A, Ruland J, Tybulewicz VL. The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat Rev Immunol 2010;10:387-402.
    • (2010) Nat Rev Immunol , vol.10 , pp. 387-402
    • Mocsai, A.1    Ruland, J.2    Tybulewicz, V.L.3
  • 52
    • 69149095639 scopus 로고    scopus 로고
    • The role of Tec family kinases in mononuclear phagocytes
    • Koprulu AD, Ellmeier W. The role of Tec family kinases in mononuclear phagocytes. Crit Rev Immunol 2009;29:317-333.
    • (2009) Crit Rev Immunol , vol.29 , pp. 317-333
    • Koprulu, A.D.1    Ellmeier, W.2
  • 53
    • 0033569768 scopus 로고    scopus 로고
    • The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complex
    • Edberg JC, et al. The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complex. J Biol Chem 1999;274:30328-30333.
    • (1999) J Biol Chem , vol.274 , pp. 30328-30333
    • Edberg, J.C.1
  • 55
    • 84867911797 scopus 로고    scopus 로고
    • The unique cytoplasmic domain of human FcgammaRIIIA regulates receptor-mediated function
    • Li X, et al. The unique cytoplasmic domain of human FcgammaRIIIA regulates receptor-mediated function. J Immunol 2012;189:4284-4294.
    • (2012) J Immunol , vol.189 , pp. 4284-4294
    • Li, X.1
  • 56
    • 44849121489 scopus 로고    scopus 로고
    • Filamin A stabilizes Fc gamma RI surface expression and prevents its lysosomal routing
    • Beekman JM, et al. Filamin A stabilizes Fc gamma RI surface expression and prevents its lysosomal routing. J Immunol 2008;180:3938-3945.
    • (2008) J Immunol , vol.180 , pp. 3938-3945
    • Beekman, J.M.1
  • 57
    • 0027940129 scopus 로고
    • Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis
    • Harrison PT, Davis W, Norman JC, Hockaday AR, Allen JM. Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis. J Biol Chem 1994;269:24396-24402.
    • (1994) J Biol Chem , vol.269 , pp. 24396-24402
    • Harrison, P.T.1    Davis, W.2    Norman, J.C.3    Hockaday, A.R.4    Allen, J.M.5
  • 58
    • 3142685132 scopus 로고    scopus 로고
    • Direct interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity
    • Beekman JM, Bakema JE, van de Winkel JG, Leusen JH. Direct interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity. Proc Natl Acad Sci USA 2004;101:10392-10397.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 10392-10397
    • Beekman, J.M.1    Bakema, J.E.2    van de Winkel, J.G.3    Leusen, J.H.4
  • 59
    • 0033564979 scopus 로고    scopus 로고
    • The Fc gamma RIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain
    • van Vugt MJ, et al. The Fc gamma RIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain. Blood 1999;94:808-817.
    • (1999) Blood , vol.94 , pp. 808-817
    • van Vugt, M.J.1
  • 60
    • 4043133804 scopus 로고    scopus 로고
    • Modulation of FcgammaRI (CD64) ligand binding by blocking peptides of periplakin
    • Beekman JM, et al. Modulation of FcgammaRI (CD64) ligand binding by blocking peptides of periplakin. J Biol Chem 2004;279:33875-33881.
    • (2004) J Biol Chem , vol.279 , pp. 33875-33881
    • Beekman, J.M.1
  • 61
    • 0015406349 scopus 로고
    • Macrophages in syngeneic animal tumours
    • Evans R. Macrophages in syngeneic animal tumours. Transplantation 1972;14:468-473.
    • (1972) Transplantation , vol.14 , pp. 468-473
    • Evans, R.1
  • 62
    • 0017103726 scopus 로고
    • Humoral factors influencing lymphocyte transformation
    • Nelson DS, Gatti RA. Humoral factors influencing lymphocyte transformation. Prog Allergy 1976;21:261-341.
    • (1976) Prog Allergy , vol.21 , pp. 261-341
    • Nelson, D.S.1    Gatti, R.A.2
  • 63
    • 0017741071 scopus 로고
    • Macrophage tumor killing: influence of the local environment
    • Hibbs JB Jr, Taintor RR, Chapman HA Jr, Weinberg JB. Macrophage tumor killing: influence of the local environment. Science 1977;197:279-282.
    • (1977) Science , vol.197 , pp. 279-282
    • Hibbs, J.B.1    Taintor, R.R.2    Chapman, H.A.3    Weinberg, J.B.4
  • 64
    • 0017739229 scopus 로고
    • Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect
    • Weinberg JB, Hibbs JB Jr. Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect. Nature 1977;269:245-247.
    • (1977) Nature , vol.269 , pp. 245-247
    • Weinberg, J.B.1    Hibbs, J.B.2
  • 65
    • 0020520274 scopus 로고
    • Inhibition of macrophage tumoricidal activity by immune complexes and altered erythrocytes
    • Esparza I, Green R, Schreiber RD. Inhibition of macrophage tumoricidal activity by immune complexes and altered erythrocytes. J Immunol 1983;131:2117-2121.
    • (1983) J Immunol , vol.131 , pp. 2117-2121
    • Esparza, I.1    Green, R.2    Schreiber, R.D.3
  • 66
    • 0028833563 scopus 로고
    • IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor
    • Feldman GM, Chuang EJ, Finbloom DS. IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor. J Immunol 1995;154:318-325.
    • (1995) J Immunol , vol.154 , pp. 318-325
    • Feldman, G.M.1    Chuang, E.J.2    Finbloom, D.S.3
  • 67
    • 33947678731 scopus 로고    scopus 로고
    • Immune complexes suppress IFN-gamma signaling by activation of the FcgammaRI pathway
    • Boekhoudt GH, Frazier-Jessen MR, Feldman GM. Immune complexes suppress IFN-gamma signaling by activation of the FcgammaRI pathway. J Leukoc Biol 2007;81:1086-1092.
    • (2007) J Leukoc Biol , vol.81 , pp. 1086-1092
    • Boekhoudt, G.H.1    Frazier-Jessen, M.R.2    Feldman, G.M.3
  • 68
    • 84921482984 scopus 로고    scopus 로고
    • Immune complexes suppress IFN-gamma-induced responses in monocytes by activating discrete members of the SRC kinase family
    • Boekhoudt GH, McGrath AG, Swisher JF, Feldman GM. Immune complexes suppress IFN-gamma-induced responses in monocytes by activating discrete members of the SRC kinase family. J Immunol 2015;194:983-989.
    • (2015) J Immunol , vol.194 , pp. 983-989
    • Boekhoudt, G.H.1    McGrath, A.G.2    Swisher, J.F.3    Feldman, G.M.4
  • 69
    • 84920863627 scopus 로고    scopus 로고
    • IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcgammaRI
    • Swisher JF, Haddad DA, McGrath AG, Boekhoudt GH, Feldman GM. IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcgammaRI. mAbs 2014;6:1377-1384.
    • (2014) mAbs , vol.6 , pp. 1377-1384
    • Swisher, J.F.1    Haddad, D.A.2    McGrath, A.G.3    Boekhoudt, G.H.4    Feldman, G.M.5
  • 70
    • 0029970787 scopus 로고    scopus 로고
    • Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor
    • Kimura T, Kihara H, Bhattacharyya S, Sakamoto H, Appella E, Siraganian RP. Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor. J Biol Chem 1996;271:27962-27968.
    • (1996) J Biol Chem , vol.271 , pp. 27962-27968
    • Kimura, T.1    Kihara, H.2    Bhattacharyya, S.3    Sakamoto, H.4    Appella, E.5    Siraganian, R.P.6
  • 71
    • 0029864882 scopus 로고    scopus 로고
    • Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides
    • Kimura T, Sakamoto H, Appella E, Siraganian RP. Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides. Mol Cell Biol 1996;16:1471-1478.
    • (1996) Mol Cell Biol , vol.16 , pp. 1471-1478
    • Kimura, T.1    Sakamoto, H.2    Appella, E.3    Siraganian, R.P.4
  • 72
    • 84905163957 scopus 로고    scopus 로고
    • Role of FcgammaRIIIA (CD16) in IVIg-mediated anti-inflammatory function
    • Ben Mkaddem S, Aloulou M, Benhamou M, Monteiro RC. Role of FcgammaRIIIA (CD16) in IVIg-mediated anti-inflammatory function. J Clin Immunol 2014;34(Suppl.):S46-S50.
    • (2014) J Clin Immunol , vol.34 , pp. S46-S50
    • Ben Mkaddem, S.1    Aloulou, M.2    Benhamou, M.3    Monteiro, R.C.4
  • 73
    • 84907008496 scopus 로고    scopus 로고
    • Shifting FcgammaRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis
    • Ben Mkaddem S, et al. Shifting FcgammaRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis. J Clin Invest 2014;124:3945-3959.
    • (2014) J Clin Invest , vol.124 , pp. 3945-3959
    • Ben Mkaddem, S.1
  • 75
    • 79954988275 scopus 로고    scopus 로고
    • How ITAMs inhibit signaling
    • Ivashkiv LB. How ITAMs inhibit signaling. Sci Signal 2011;4:pe20.
    • (2011) Sci Signal , vol.4 , pp. pe20
    • Ivashkiv, L.B.1
  • 76
    • 77957016117 scopus 로고    scopus 로고
    • The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production
    • Gallo P, Goncalves R, Mosser DM. The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production. Immunol Lett 2010;133:70-77.
    • (2010) Immunol Lett , vol.133 , pp. 70-77
    • Gallo, P.1    Goncalves, R.2    Mosser, D.M.3
  • 77
    • 67651095947 scopus 로고    scopus 로고
    • Differential signal transduction, membrane trafficking, and immune effector functions mediated by Fc gamma RI versus Fc gamma RIIa
    • Dai XL, et al. Differential signal transduction, membrane trafficking, and immune effector functions mediated by Fc gamma RI versus Fc gamma RIIa. Blood 2009;114:318-327.
    • (2009) Blood , vol.114 , pp. 318-327
    • Dai, X.L.1
  • 78
    • 0037606153 scopus 로고    scopus 로고
    • Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis
    • Ji JD, et al. Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis. J Exp Med 2003;197:1573-1583.
    • (2003) J Exp Med , vol.197 , pp. 1573-1583
    • Ji, J.D.1
  • 80
    • 18344370440 scopus 로고    scopus 로고
    • FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection
    • Ioan-Facsinay A, et al. FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 2002;16:391-402.
    • (2002) Immunity , vol.16 , pp. 391-402
    • Ioan-Facsinay, A.1
  • 81
    • 0032490575 scopus 로고    scopus 로고
    • Reversal of proinflammatory responses by ligating the macrophage Fc gamma receptor type I
    • Sutterwala FS, Noel GJ, Salgame P, Mosser DM. Reversal of proinflammatory responses by ligating the macrophage Fc gamma receptor type I. J Exp Med 1998;188:217-222.
    • (1998) J Exp Med , vol.188 , pp. 217-222
    • Sutterwala, F.S.1    Noel, G.J.2    Salgame, P.3    Mosser, D.M.4
  • 82
    • 84874275259 scopus 로고    scopus 로고
    • FcalphaRI-mediated inhibition of IL-12 production and priming by IFN-gamma of human monocytes and dendritic cells
    • Lecocq M, Detry B, Guisset A, Pilette C. FcalphaRI-mediated inhibition of IL-12 production and priming by IFN-gamma of human monocytes and dendritic cells. J Immunol 2013;190:2362-2371.
    • (2013) J Immunol , vol.190 , pp. 2362-2371
    • Lecocq, M.1    Detry, B.2    Guisset, A.3    Pilette, C.4
  • 83
    • 84926664616 scopus 로고    scopus 로고
    • Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages
    • Vogelpoel LT, et al. Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages. Nat Commun 2014;5:5444.
    • (2014) Nat Commun , vol.5 , pp. 5444
    • Vogelpoel, L.T.1
  • 84
    • 0030803892 scopus 로고    scopus 로고
    • High levels of cerebrospinal fluid IgM binding to myelin basic protein are associated with early benign course in multiple sclerosis
    • Annunziata P, Pluchino S, Martino T, Guazzi G. High levels of cerebrospinal fluid IgM binding to myelin basic protein are associated with early benign course in multiple sclerosis. J Neuroimmunol 1997;77:128-133.
    • (1997) J Neuroimmunol , vol.77 , pp. 128-133
    • Annunziata, P.1    Pluchino, S.2    Martino, T.3    Guazzi, G.4
  • 85
    • 84875364108 scopus 로고    scopus 로고
    • Immunosuppressive monoclonal antibody to CD64 from patients with long-term stable multiple sclerosis
    • Annunziata P, Cioni C, Cantalupo L, Di Genova G, Savellini GG, Cusi G. Immunosuppressive monoclonal antibody to CD64 from patients with long-term stable multiple sclerosis. J Neuroimmunol 2013;256:62-70.
    • (2013) J Neuroimmunol , vol.256 , pp. 62-70
    • Annunziata, P.1    Cioni, C.2    Cantalupo, L.3    Di Genova, G.4    Savellini, G.G.5    Cusi, G.6
  • 86
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990;346:183-187.
    • (1990) Nature , vol.346 , pp. 183-187
    • Ota, K.1    Matsui, M.2    Milford, E.L.3    Mackin, G.A.4    Weiner, H.L.5    Hafler, D.A.6
  • 87
    • 77951523463 scopus 로고    scopus 로고
    • Bispecific antibodies for cancer therapy: the light at the end of the tunnel?
    • Chames P, Baty D. Bispecific antibodies for cancer therapy: the light at the end of the tunnel? mAbs 2009;1:539-547.
    • (2009) mAbs , vol.1 , pp. 539-547
    • Chames, P.1    Baty, D.2
  • 88
    • 77957160633 scopus 로고    scopus 로고
    • Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
    • Halstead SB, Mahalingam S, Marovich MA, Ubol S, Mosser DM. Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes. Lancet Infect Dis 2010;10:712-722.
    • (2010) Lancet Infect Dis , vol.10 , pp. 712-722
    • Halstead, S.B.1    Mahalingam, S.2    Marovich, M.A.3    Ubol, S.4    Mosser, D.M.5
  • 89
    • 33749454503 scopus 로고    scopus 로고
    • Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32)
    • Rodrigo WW, Jin X, Blackley SD, Rose RC, Schlesinger JJ. Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32). J Virol 2006;80:10128-10138.
    • (2006) J Virol , vol.80 , pp. 10128-10138
    • Rodrigo, W.W.1    Jin, X.2    Blackley, S.D.3    Rose, R.C.4    Schlesinger, J.J.5
  • 90
    • 84923052917 scopus 로고    scopus 로고
    • Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection
    • Yamada DH, et al. Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection. Immunity 2015;42:379-390.
    • (2015) Immunity , vol.42 , pp. 379-390
    • Yamada, D.H.1
  • 91
    • 84922970995 scopus 로고    scopus 로고
    • Antibody effector functions mediated by Fcgamma-receptors are compromised during persistent viral infection
    • Wieland A, et al. Antibody effector functions mediated by Fcgamma-receptors are compromised during persistent viral infection. Immunity 2015;42:367-378.
    • (2015) Immunity , vol.42 , pp. 367-378
    • Wieland, A.1
  • 92
    • 15444364277 scopus 로고    scopus 로고
    • A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
    • Miles SA, Conrad SM, Alves RG, Jeronimo SM, Mosser DM. A role for IgG immune complexes during infection with the intracellular pathogen Leishmania. J Exp Med 2005;201:747-754.
    • (2005) J Exp Med , vol.201 , pp. 747-754
    • Miles, S.A.1    Conrad, S.M.2    Alves, R.G.3    Jeronimo, S.M.4    Mosser, D.M.5
  • 93
    • 84945283981 scopus 로고    scopus 로고
    • Challenging the Th1 paradigm: a detrimental role for IFN-gamma and IFN-regulated CD64 in human leishmaniasis
    • Van Weyenbergh J, et al. Challenging the Th1 paradigm: a detrimental role for IFN-gamma and IFN-regulated CD64 in human leishmaniasis. Cytokine 2013;63:306.
    • (2013) Cytokine , vol.63 , pp. 306
    • Van Weyenbergh, J.1
  • 95
    • 0038798080 scopus 로고    scopus 로고
    • Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene
    • Szalai AJ, et al. Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene. Arthritis Rheum 2003;48:1602-1611.
    • (2003) Arthritis Rheum , vol.48 , pp. 1602-1611
    • Szalai, A.J.1
  • 96
    • 31044446853 scopus 로고    scopus 로고
    • Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein
    • Rodriguez W, et al. Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein. Arthritis Rheum 2006;54:325-335.
    • (2006) Arthritis Rheum , vol.54 , pp. 325-335
    • Rodriguez, W.1
  • 97
    • 84929625543 scopus 로고    scopus 로고
    • C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis
    • Zhang L, et al. C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis. J Immunol 2015;194:5243-5252.
    • (2015) J Immunol , vol.194 , pp. 5243-5252
    • Zhang, L.1
  • 98
    • 0037114170 scopus 로고    scopus 로고
    • C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R
    • Mold C, Rodriguez W, Rodic-Polic B, Du Clos TW. C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R. J Immunol 2002;169:7019-7025.
    • (2002) J Immunol , vol.169 , pp. 7019-7025
    • Mold, C.1    Rodriguez, W.2    Rodic-Polic, B.3    Du Clos, T.W.4
  • 99
    • 63149133894 scopus 로고    scopus 로고
    • Macrophages activated by C-reactive protein through Fc gamma RI transfer suppression of immune thrombocytopenia
    • Marjon KD, Marnell LL, Mold C, Du Clos TW. Macrophages activated by C-reactive protein through Fc gamma RI transfer suppression of immune thrombocytopenia. J Immunol 2009;182:1397-1403.
    • (2009) J Immunol , vol.182 , pp. 1397-1403
    • Marjon, K.D.1    Marnell, L.L.2    Mold, C.3    Du Clos, T.W.4
  • 100
    • 84868117632 scopus 로고    scopus 로고
    • FcgammaRI mediates serum amyloid P inhibition of fibrocyte differentiation
    • Crawford JR, Pilling D, Gomer RH. FcgammaRI mediates serum amyloid P inhibition of fibrocyte differentiation. J Leukoc Biol 2012;92:699-711.
    • (2012) J Leukoc Biol , vol.92 , pp. 699-711
    • Crawford, J.R.1    Pilling, D.2    Gomer, R.H.3
  • 101
    • 84905058971 scopus 로고    scopus 로고
    • Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcgammaRI
    • Pilling D, Crawford JR, Verbeek JS, Gomer RH. Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcgammaRI. J Leukoc Biol 2014;96:275-282.
    • (2014) J Leukoc Biol , vol.96 , pp. 275-282
    • Pilling, D.1    Crawford, J.R.2    Verbeek, J.S.3    Gomer, R.H.4
  • 102
    • 84925061777 scopus 로고    scopus 로고
    • The long pentraxin PTX3 promotes fibrocyte differentiation
    • Pilling D, Cox N, Vakil V, Verbeek JS, Gomer RH. The long pentraxin PTX3 promotes fibrocyte differentiation. PLoS ONE 2015;10:e0119709.
    • (2015) PLoS ONE , vol.10 , pp. e0119709
    • Pilling, D.1    Cox, N.2    Vakil, V.3    Verbeek, J.S.4    Gomer, R.H.5
  • 103
    • 84924602786 scopus 로고    scopus 로고
    • Macrophages are critical effectors of antibody therapies for cancer
    • Weiskopf K, Weissman IL. Macrophages are critical effectors of antibody therapies for cancer. mAbs 2015;7:303-310.
    • (2015) mAbs , vol.7 , pp. 303-310
    • Weiskopf, K.1    Weissman, I.L.2
  • 104
    • 84867055822 scopus 로고    scopus 로고
    • Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases
    • Hristodorov D, Mladenov R, Huhn M, Barth S, Thepen T. Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases. Toxins (Basel) 2012;4:676-694.
    • (2012) Toxins (Basel) , vol.4 , pp. 676-694
    • Hristodorov, D.1    Mladenov, R.2    Huhn, M.3    Barth, S.4    Thepen, T.5
  • 105
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: a comprehensive review
    • Tracey D, Klareskog L, Sasso EH, Salfeld JG, Tak PP. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther 2008;117:244-279.
    • (2008) Pharmacol Ther , vol.117 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3    Salfeld, J.G.4    Tak, P.P.5
  • 108
    • 84857373545 scopus 로고    scopus 로고
    • Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro
    • Vos AC, et al. Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro. Inflamm Bowel Dis 2012;18:401-408.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 401-408
    • Vos, A.C.1
  • 109
    • 84905380032 scopus 로고    scopus 로고
    • Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient mice
    • Zhang H, et al. Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient mice. World J Gastroenterol 2014;20:9106-9115.
    • (2014) World J Gastroenterol , vol.20 , pp. 9106-9115
    • Zhang, H.1
  • 110
    • 33744933432 scopus 로고    scopus 로고
    • A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease
    • Braat H, et al. A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease. Clin Gastroenterol Hepatol 2006;4:754-759.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 754-759
    • Braat, H.1
  • 111
    • 84896117860 scopus 로고    scopus 로고
    • In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease
    • Atreya R, et al. In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease. Nat Med 2014;20:313-318.
    • (2014) Nat Med , vol.20 , pp. 313-318
    • Atreya, R.1
  • 112
    • 84913591914 scopus 로고    scopus 로고
    • Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy
    • Hristodorov D, Mladenov R, Brehm H, Fischer R, Barth S, Thepen T. Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy. mAbs 2014;6:1283-1289.
    • (2014) mAbs , vol.6 , pp. 1283-1289
    • Hristodorov, D.1    Mladenov, R.2    Brehm, H.3    Fischer, R.4    Barth, S.5    Thepen, T.6
  • 113
    • 84871770952 scopus 로고    scopus 로고
    • A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer
    • Mellor JD, Brown MP, Irving HR, Zalcberg JR, Dobrovic A. A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer. J Hematol Oncol 2013;6:1.
    • (2013) J Hematol Oncol , vol.6 , pp. 1
    • Mellor, J.D.1    Brown, M.P.2    Irving, H.R.3    Zalcberg, J.R.4    Dobrovic, A.5
  • 114
    • 0027304602 scopus 로고
    • Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy
    • Valerius T, et al. Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy. Blood 1993;82:931-939.
    • (1993) Blood , vol.82 , pp. 931-939
    • Valerius, T.1
  • 116
    • 32944454324 scopus 로고    scopus 로고
    • The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma
    • Bevaart L, Jansen MJ, van Vugt MJ, Verbeek JS, van de Winkel JG, Leusen JH. The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma. Cancer Res 2006;66:1261-1264.
    • (2006) Cancer Res , vol.66 , pp. 1261-1264
    • Bevaart, L.1    Jansen, M.J.2    van Vugt, M.J.3    Verbeek, J.S.4    van de Winkel, J.G.5    Leusen, J.H.6
  • 117
    • 77956262454 scopus 로고    scopus 로고
    • Experimentally induced liver metastases from colorectal cancer can be prevented by mononuclear phagocyte-mediated monoclonal antibody therapy
    • van der Bij GJ, et al. Experimentally induced liver metastases from colorectal cancer can be prevented by mononuclear phagocyte-mediated monoclonal antibody therapy. J Hepatol 2010;53:677-685.
    • (2010) J Hepatol , vol.53 , pp. 677-685
    • van der Bij, G.J.1
  • 118
    • 58149198794 scopus 로고    scopus 로고
    • Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV
    • Otten MA, et al. Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV. J Immunol 2008;181:6829-6836.
    • (2008) J Immunol , vol.181 , pp. 6829-6836
    • Otten, M.A.1
  • 119
    • 84902548351 scopus 로고    scopus 로고
    • Anti-tumor activity of human IgG1 anti-gp75 TA99 mAb against B16F10 melanoma in human FcgammaRI transgenic mice
    • Boross P, et al. Anti-tumor activity of human IgG1 anti-gp75 TA99 mAb against B16F10 melanoma in human FcgammaRI transgenic mice. Immunol Lett 2014;160:151-157.
    • (2014) Immunol Lett , vol.160 , pp. 151-157
    • Boross, P.1
  • 120
    • 77955600434 scopus 로고    scopus 로고
    • Regulation of angiogenesis by macrophages
    • Apte RS. Regulation of angiogenesis by macrophages. Adv Exp Med Biol 2010;664:15-19.
    • (2010) Adv Exp Med Biol , vol.664 , pp. 15-19
    • Apte, R.S.1
  • 121
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002;23:549-555.
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 123
    • 80052490775 scopus 로고    scopus 로고
    • Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab
    • Pander J, et al. Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab. Clin Cancer Res 2011;17:5668-5673.
    • (2011) Clin Cancer Res , vol.17 , pp. 5668-5673
    • Pander, J.1
  • 124
    • 84921916858 scopus 로고    scopus 로고
    • Tumor-associated macrophages as an emerging target against tumors: creating a new path from bench to bedside
    • Jinushi M, Komohara Y. Tumor-associated macrophages as an emerging target against tumors: creating a new path from bench to bedside. Biochim Biophys Acta 2015;1855:123-130.
    • (2015) Biochim Biophys Acta , vol.1855 , pp. 123-130
    • Jinushi, M.1    Komohara, Y.2
  • 125
    • 84885205350 scopus 로고    scopus 로고
    • Targeting tumor-infiltrating macrophages to combat cancer
    • Panni RZ, Linehan DC, DeNardo DG. Targeting tumor-infiltrating macrophages to combat cancer. Immunother UK 2013;5:1075-1087.
    • (2013) Immunother UK , vol.5 , pp. 1075-1087
    • Panni, R.Z.1    Linehan, D.C.2    DeNardo, D.G.3
  • 126
    • 84869856891 scopus 로고    scopus 로고
    • Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function
    • Grugan KD, et al. Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function. J Immunol 2012;189:5457-5466.
    • (2012) J Immunol , vol.189 , pp. 5457-5466
    • Grugan, K.D.1
  • 127
    • 35348843627 scopus 로고    scopus 로고
    • A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone
    • Taskinen M, Karjalainen-Lindsberg ML, Nyman H, Eerola LM, Leppa S. A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone. Clin Cancer Res 2007;13:5784-5789.
    • (2007) Clin Cancer Res , vol.13 , pp. 5784-5789
    • Taskinen, M.1    Karjalainen-Lindsberg, M.L.2    Nyman, H.3    Eerola, L.M.4    Leppa, S.5
  • 128
    • 38649108461 scopus 로고    scopus 로고
    • High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial
    • Canioni D, et al. High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial. J Clin Oncol 2008;26:440-446.
    • (2008) J Clin Oncol , vol.26 , pp. 440-446
    • Canioni, D.1
  • 129
    • 84977126665 scopus 로고    scopus 로고
    • The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer
    • Stewart R, Hammond SA, Oberst M, Wilkinson RW. The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer. J Immunother Cancer 2014;2:29-38.
    • (2014) J Immunother Cancer , vol.2 , pp. 29-38
    • Stewart, R.1    Hammond, S.A.2    Oberst, M.3    Wilkinson, R.W.4
  • 130
    • 79551575923 scopus 로고    scopus 로고
    • Advances in the assessment and control of the effector functions of therapeutic antibodies
    • Jiang XR, et al. Advances in the assessment and control of the effector functions of therapeutic antibodies. Nat Rev Drug Discov 2011;10:101-111.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 101-111
    • Jiang, X.R.1
  • 131
    • 0027456571 scopus 로고
    • Structural motifs involved in human IgG antibody effector functions
    • Greenwood J, Clark M, Waldmann H. Structural motifs involved in human IgG antibody effector functions. Eur J Immunol 1993;23:1098-1104.
    • (1993) Eur J Immunol , vol.23 , pp. 1098-1104
    • Greenwood, J.1    Clark, M.2    Waldmann, H.3
  • 133
    • 33748416499 scopus 로고    scopus 로고
    • Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
    • Suntharalingam G, et al. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med 2006;355:1018-1028.
    • (2006) N Engl J Med , vol.355 , pp. 1018-1028
    • Suntharalingam, G.1
  • 134
    • 84896514032 scopus 로고    scopus 로고
    • + immune cells contribute to the TGN1412-triggered cytokine response
    • + immune cells contribute to the TGN1412-triggered cytokine response. J Immunol 2014;192:2091-2098.
    • (2014) J Immunol , vol.192 , pp. 2091-2098
    • Bartholomaeus, P.1
  • 135
    • 84871122818 scopus 로고    scopus 로고
    • Antibody C region influences TGN1412-like functional activity in vitro
    • Ball C, et al. Antibody C region influences TGN1412-like functional activity in vitro. J Immunol 2012;189:5831-5840.
    • (2012) J Immunol , vol.189 , pp. 5831-5840
    • Ball, C.1
  • 136
    • 84898045276 scopus 로고    scopus 로고
    • A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity
    • Lux A, et al. A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity. Cell Rep 2014;7:236-248.
    • (2014) Cell Rep , vol.7 , pp. 236-248
    • Lux, A.1
  • 137
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: nomenclature and experimental guidelines
    • Murray PJ, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 2014;41:14-20.
    • (2014) Immunity , vol.41 , pp. 14-20
    • Murray, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.