-
1
-
-
84945275929
-
Regulatory considerations in the development of monoclonal antibodies for diagnosis and therapy
-
Wiley-VCH Verlag GmbH & Co.: KGaA, Weinheim, Germany
-
Shapiro MA, Swann PG, Ricci MS. Regulatory considerations in the development of monoclonal antibodies for diagnosis and therapy. Handbook of Therapeutic Antibodies. Wiley-VCH Verlag GmbH & Co.: KGaA, Weinheim, Germany, 2007;1231-1262.
-
(2007)
Handbook of Therapeutic Antibodies
, pp. 1231-1262
-
-
Shapiro, M.A.1
Swann, P.G.2
Ricci, M.S.3
-
2
-
-
64249112661
-
Current constructs and targets in clinical development for antibody-based cancer therapy
-
Deckert PM. Current constructs and targets in clinical development for antibody-based cancer therapy. Curr Drug Targets 2009;10:158-175.
-
(2009)
Curr Drug Targets
, vol.10
, pp. 158-175
-
-
Deckert, P.M.1
-
3
-
-
37549036732
-
Fcgamma receptors as regulators of immune responses
-
Nimmerjahn F, Ravetch JV. Fcgamma receptors as regulators of immune responses. Nat Rev Immunol 2008;8:34-47.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 34-47
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
5
-
-
0031646641
-
Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts
-
Ernst LK, Duchemin AM, Miller KL, Anderson CL. Molecular characterization of six variant Fcgamma receptor class I (CD64) transcripts. Mol Immunol 1998;35:943-954.
-
(1998)
Mol Immunol
, vol.35
, pp. 943-954
-
-
Ernst, L.K.1
Duchemin, A.M.2
Miller, K.L.3
Anderson, C.L.4
-
6
-
-
0032896785
-
The alternatively spliced CD64 transcript Fc gamma Rlb2 does not specify a surface-expressed isoform
-
van Vugt MJ, Reefman E, Zeelenberg I, Boonen G, Leusen JHW, van de Winkel JGJ. The alternatively spliced CD64 transcript Fc gamma Rlb2 does not specify a surface-expressed isoform. Eur J Immunol 1999;29:143-149.
-
(1999)
Eur J Immunol
, vol.29
, pp. 143-149
-
-
van Vugt, M.J.1
Reefman, E.2
Zeelenberg, I.3
Boonen, G.4
Leusen, J.H.W.5
van de Winkel, J.G.J.6
-
7
-
-
0038532175
-
FcgammaR polymorphisms: implications for function, disease susceptibility and immunotherapy
-
van Sorge NM, van der Pol WL, van de Winkel JG. FcgammaR polymorphisms: implications for function, disease susceptibility and immunotherapy. Tissue Antigens 2003;61:189-202.
-
(2003)
Tissue Antigens
, vol.61
, pp. 189-202
-
-
van Sorge, N.M.1
van der Pol, W.L.2
van de Winkel, J.G.3
-
8
-
-
0031674586
-
The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a
-
Hulett MD, Hogarth PM. The second and third extracellular domains of FcgammaRI (CD64) confer the unique high affinity binding of IgG2a. Mol Immunol 1998;35:989-996.
-
(1998)
Mol Immunol
, vol.35
, pp. 989-996
-
-
Hulett, M.D.1
Hogarth, P.M.2
-
9
-
-
81755172412
-
Crystal structure of Fcgamma receptor I and its implication in high affinity gamma-immunoglobulin binding
-
Lu J, Ellsworth JL, Hamacher N, Oak SW, Sun PD. Crystal structure of Fcgamma receptor I and its implication in high affinity gamma-immunoglobulin binding. J Biol Chem 2011;286:40608-40613.
-
(2011)
J Biol Chem
, vol.286
, pp. 40608-40613
-
-
Lu, J.1
Ellsworth, J.L.2
Hamacher, N.3
Oak, S.W.4
Sun, P.D.5
-
10
-
-
84922360962
-
Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding
-
Lu J, Chu J, Zou Z, Hamacher NB, Rixon MW, Sun PD. Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding. Proc Natl Acad Sci USA 2015;112:833-838.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 833-838
-
-
Lu, J.1
Chu, J.2
Zou, Z.3
Hamacher, N.B.4
Rixon, M.W.5
Sun, P.D.6
-
11
-
-
84928776106
-
Structural basis for binding of human IgG1 to its high-affinity human receptor FcgammaRI
-
Kiyoshi M, et al. Structural basis for binding of human IgG1 to its high-affinity human receptor FcgammaRI. Nat Commun 2015;6:6866.
-
(2015)
Nat Commun
, vol.6
, pp. 6866
-
-
Kiyoshi, M.1
-
12
-
-
0029875464
-
FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo
-
vanVugt MJ, et al. FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo. Blood 1996;87:3593-3599.
-
(1996)
Blood
, vol.87
, pp. 3593-3599
-
-
vanVugt, M.J.1
-
13
-
-
0026540751
-
Multichain immune recognition receptors: similarities in structure and signaling pathways
-
Keegan AD, Paul WE. Multichain immune recognition receptors: similarities in structure and signaling pathways. Immunol Today 1992;13:63-68.
-
(1992)
Immunol Today
, vol.13
, pp. 63-68
-
-
Keegan, A.D.1
Paul, W.E.2
-
14
-
-
0028042424
-
FcR gamma chain deletion results in pleiotrophic effector cell defects
-
Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV. FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 1994;76:519-529.
-
(1994)
Cell
, vol.76
, pp. 519-529
-
-
Takai, T.1
Li, M.2
Sylvestre, D.3
Clynes, R.4
Ravetch, J.V.5
-
15
-
-
0030929805
-
Fc receptor biology
-
Daeron M. Fc receptor biology. Annu Rev Immunol 1997;15:203-234.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 203-234
-
-
Daeron, M.1
-
16
-
-
0024531803
-
Isolation and expression of functional high-affinity Fc receptor complementary DNAs
-
Allen JM, Seed B. Isolation and expression of functional high-affinity Fc receptor complementary DNAs. Science 1989;243:378-381.
-
(1989)
Science
, vol.243
, pp. 378-381
-
-
Allen, J.M.1
Seed, B.2
-
17
-
-
0036009179
-
FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses
-
Barnes N, Gavin AL, Tan PS, Mottram P, Koentgen F, Hogarth PM. FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 2002;16:379-389.
-
(2002)
Immunity
, vol.16
, pp. 379-389
-
-
Barnes, N.1
Gavin, A.L.2
Tan, P.S.3
Mottram, P.4
Koentgen, F.5
Hogarth, P.M.6
-
18
-
-
0030818074
-
Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects
-
Schiff DE, Rae J, Martin TR, Davis BH, Curnutte JT. Increased phagocyte Fc gammaRI expression and improved Fc gamma-receptor-mediated phagocytosis after in vivo recombinant human interferon-gamma treatment of normal human subjects. Blood 1997;90:3187-3194.
-
(1997)
Blood
, vol.90
, pp. 3187-3194
-
-
Schiff, D.E.1
Rae, J.2
Martin, T.R.3
Davis, B.H.4
Curnutte, J.T.5
-
19
-
-
48949118204
-
Neutrophil and monocyte CD64 and CD163 expression in critically ill neonates and children with sepsis: comparison of fluorescence intensities and calculated indexes
-
Groselj-Grenc M, Ihan A, Derganc M. Neutrophil and monocyte CD64 and CD163 expression in critically ill neonates and children with sepsis: comparison of fluorescence intensities and calculated indexes. Mediators Inflamm 2008;2008:202646.
-
(2008)
Mediators Inflamm
, vol.2008
, pp. 202646
-
-
Groselj-Grenc, M.1
Ihan, A.2
Derganc, M.3
-
20
-
-
0026065071
-
Fc gamma-receptors on Langerhans' cells and keratinocytes in suspension from normal skin characterized using soluble immune complexes and monoclonal antibodies
-
Tigalonowa M, Bjerke JR, Matre R. Fc gamma-receptors on Langerhans' cells and keratinocytes in suspension from normal skin characterized using soluble immune complexes and monoclonal antibodies. Acta Derm Venereol 1991;71:99-103.
-
(1991)
Acta Derm Venereol
, vol.71
, pp. 99-103
-
-
Tigalonowa, M.1
Bjerke, J.R.2
Matre, R.3
-
21
-
-
0017160140
-
Appearance of IgG (Fc) receptor(s) on cultured human fibroblasts infected with human cytomegalovirus
-
Rahman AA, Teschner M, Sethi KK, Brandis H. Appearance of IgG (Fc) receptor(s) on cultured human fibroblasts infected with human cytomegalovirus. J Immunol 1976;117:253-258.
-
(1976)
J Immunol
, vol.117
, pp. 253-258
-
-
Rahman, A.A.1
Teschner, M.2
Sethi, K.K.3
Brandis, H.4
-
22
-
-
84865293881
-
Fc gamma receptor CD64 modulates the inhibitory activity of infliximab
-
Wojtal KA, et al. Fc gamma receptor CD64 modulates the inhibitory activity of infliximab. PLoS ONE 2012;7:e43361.
-
(2012)
PLoS ONE
, vol.7
, pp. e43361
-
-
Wojtal, K.A.1
-
23
-
-
0031595604
-
Detection of Fcgamma receptors on human endothelial cells stimulated with cytokines tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma)
-
Pan LF, Kreisle RA, Shi YD. Detection of Fcgamma receptors on human endothelial cells stimulated with cytokines tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma). Clin Exp Immunol 1998;112:533-538.
-
(1998)
Clin Exp Immunol
, vol.112
, pp. 533-538
-
-
Pan, L.F.1
Kreisle, R.A.2
Shi, Y.D.3
-
24
-
-
79952162741
-
Functional expression of IgG-Fc receptors in human airway smooth muscle cells
-
Xia YC, et al. Functional expression of IgG-Fc receptors in human airway smooth muscle cells. Am J Respir Cell Mol Biol 2011;44:665-672.
-
(2011)
Am J Respir Cell Mol Biol
, vol.44
, pp. 665-672
-
-
Xia, Y.C.1
-
25
-
-
77956393132
-
Involvement of Fc receptors in disorders of the central nervous system
-
Okun E, Mattson MP, Arumugam TV. Involvement of Fc receptors in disorders of the central nervous system. NeuroMol Med 2010;12:164-178.
-
(2010)
NeuroMol Med
, vol.12
, pp. 164-178
-
-
Okun, E.1
Mattson, M.P.2
Arumugam, T.V.3
-
26
-
-
0020564130
-
Immune interferon induces the receptor for monomeric IgG1 on human monocytic and myeloid cells
-
Perussia B, Dayton ET, Lazarus R, Fanning V, Trinchieri G. Immune interferon induces the receptor for monomeric IgG1 on human monocytic and myeloid cells. J Exp Med 1983;158:1092-1113.
-
(1983)
J Exp Med
, vol.158
, pp. 1092-1113
-
-
Perussia, B.1
Dayton, E.T.2
Lazarus, R.3
Fanning, V.4
Trinchieri, G.5
-
27
-
-
0020564534
-
Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes
-
Guyre PM, Morganelli PM, Miller R. Recombinant immune interferon increases immunoglobulin G Fc receptors on cultured human mononuclear phagocytes. J Clin Invest 1983;72:393-397.
-
(1983)
J Clin Invest
, vol.72
, pp. 393-397
-
-
Guyre, P.M.1
Morganelli, P.M.2
Miller, R.3
-
28
-
-
0027057265
-
IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10
-
te Velde AA, de Waal Malefijt R, Huijbens RJ, de Vries JE, Figdor CG. IL-10 stimulates monocyte Fc gamma R surface expression and cytotoxic activity. Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-gamma, IL-4, and IL-10. J Immunol 1992;149:4048-4052.
-
(1992)
J Immunol
, vol.149
, pp. 4048-4052
-
-
te Velde, A.A.1
de Waal Malefijt, R.2
Huijbens, R.J.3
de Vries, J.E.4
Figdor, C.G.5
-
29
-
-
0026000790
-
Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor
-
Repp R, et al. Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor. Blood 1991;78:885-889.
-
(1991)
Blood
, vol.78
, pp. 885-889
-
-
Repp, R.1
-
30
-
-
0025361669
-
IL-4 decreases Fc gamma R membrane expression and Fc gamma R-mediated cytotoxic activity of human monocytes
-
te Velde AA, Huijbens RJ, de Vries JE, Figdor CG. IL-4 decreases Fc gamma R membrane expression and Fc gamma R-mediated cytotoxic activity of human monocytes. J Immunol 1990;144:3046-3051.
-
(1990)
J Immunol
, vol.144
, pp. 3046-3051
-
-
te Velde, A.A.1
Huijbens, R.J.2
de Vries, J.E.3
Figdor, C.G.4
-
31
-
-
71549115144
-
CD64 index provides simple and predictive testing for detection and monitoring of sepsis and bacterial infection in hospital patients
-
Icardi M, Erickson Y, Kilborn S, Stewart B, Grief B, Scharnweber G. CD64 index provides simple and predictive testing for detection and monitoring of sepsis and bacterial infection in hospital patients. J Clin Microbiol 2009;47:3914-3919.
-
(2009)
J Clin Microbiol
, vol.47
, pp. 3914-3919
-
-
Icardi, M.1
Erickson, Y.2
Kilborn, S.3
Stewart, B.4
Grief, B.5
Scharnweber, G.6
-
32
-
-
70349478739
-
Neutrophil CD64: a diagnostic marker for infection and sepsis
-
Hoffmann JJ. Neutrophil CD64: a diagnostic marker for infection and sepsis. Clin Chem Lab Med 2009;47:903-916.
-
(2009)
Clin Chem Lab Med
, vol.47
, pp. 903-916
-
-
Hoffmann, J.J.1
-
33
-
-
84869224881
-
Neutrophil CD64 expression is elevated in acetaminophen-induced acute liver failure
-
author reply 9-60.
-
Abeles RD, et al. Neutrophil CD64 expression is elevated in acetaminophen-induced acute liver failure. Am J Respir Crit Care Med 2012;186:1058-1059; author reply 9-60.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 1058-1059
-
-
Abeles, R.D.1
-
34
-
-
84903713683
-
CD64 expression is increased in patients with severe acute pancreatitis: clinical significance
-
Zhang H, et al. CD64 expression is increased in patients with severe acute pancreatitis: clinical significance. Gut Liv 2014;8:445-451.
-
(2014)
Gut Liv
, vol.8
, pp. 445-451
-
-
Zhang, H.1
-
35
-
-
84931843587
-
Neutrophil and monocyte Toll-like receptor 4, CD11b and reactive oxygen intermediates and neuroimaging outcomes in preterm infants
-
O'Hare FM, et al. Neutrophil and monocyte Toll-like receptor 4, CD11b and reactive oxygen intermediates and neuroimaging outcomes in preterm infants. Pediatr Res 2015;78:82-90.
-
(2015)
Pediatr Res
, vol.78
, pp. 82-90
-
-
O'Hare, F.M.1
-
36
-
-
55149094739
-
Interleukin-10: new perspectives on an old cytokine
-
Mosser DM, Zhang X. Interleukin-10: new perspectives on an old cytokine. Immunol Rev 2008;226:205-218.
-
(2008)
Immunol Rev
, vol.226
, pp. 205-218
-
-
Mosser, D.M.1
Zhang, X.2
-
37
-
-
0027492915
-
Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10
-
de Waal Malefyt R, et al. Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10. J Immunol 1993;151:6370-6381.
-
(1993)
J Immunol
, vol.151
, pp. 6370-6381
-
-
de Waal Malefyt, R.1
-
38
-
-
0343618515
-
Cooperation among Stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes
-
Aittomaki S, Pesu M, Groner B, Janne OA, Palvimo JJ, Silvennoinen O. Cooperation among Stat1, glucocorticoid receptor, and PU.1 in transcriptional activation of the high-affinity Fc gamma receptor I in monocytes. J Immunol 2000;164:5689-5697.
-
(2000)
J Immunol
, vol.164
, pp. 5689-5697
-
-
Aittomaki, S.1
Pesu, M.2
Groner, B.3
Janne, O.A.4
Palvimo, J.J.5
Silvennoinen, O.6
-
39
-
-
78650043719
-
Cytokine-induced immune complex binding to the high-affinity IgG receptor, Fc gamma RI, in the presence of monomeric IgG
-
van der Poel CE, et al. Cytokine-induced immune complex binding to the high-affinity IgG receptor, Fc gamma RI, in the presence of monomeric IgG. Blood 2010;116:5327-5333.
-
(2010)
Blood
, vol.116
, pp. 5327-5333
-
-
van der Poel, C.E.1
-
40
-
-
84862495640
-
Properties of mouse and human IgG receptors and their contribution to disease models
-
Bruhns P. Properties of mouse and human IgG receptors and their contribution to disease models. Blood 2012;119:5640-5649.
-
(2012)
Blood
, vol.119
, pp. 5640-5649
-
-
Bruhns, P.1
-
41
-
-
65549114676
-
Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses
-
Bruhns P, et al. Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses. Blood 2009;113:3716-3725.
-
(2009)
Blood
, vol.113
, pp. 3716-3725
-
-
Bruhns, P.1
-
42
-
-
84875998684
-
Impact of immune complex size and glycosylation on IgG binding to human FcgammaRs
-
Lux A, Yu X, Scanlan CN, Nimmerjahn F. Impact of immune complex size and glycosylation on IgG binding to human FcgammaRs. J Immunol 2013;190:4315-4323.
-
(2013)
J Immunol
, vol.190
, pp. 4315-4323
-
-
Lux, A.1
Yu, X.2
Scanlan, C.N.3
Nimmerjahn, F.4
-
43
-
-
0032528045
-
Gain-of-function mutations in FcgammaRI of NOD mice: implications for the evolution of the Ig superfamily
-
Gavin AL, Tan PS, Hogarth PM. Gain-of-function mutations in FcgammaRI of NOD mice: implications for the evolution of the Ig superfamily. EMBO J 1998;17:3850-3857.
-
(1998)
EMBO J
, vol.17
, pp. 3850-3857
-
-
Gavin, A.L.1
Tan, P.S.2
Hogarth, P.M.3
-
44
-
-
0026592447
-
Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene
-
Osman N, Kozak CA, McKenzie IF, Hogarth PM. Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene. J Immunol 1992;148:1570-1575.
-
(1992)
J Immunol
, vol.148
, pp. 1570-1575
-
-
Osman, N.1
Kozak, C.A.2
McKenzie, I.F.3
Hogarth, P.M.4
-
45
-
-
0025886261
-
Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene
-
van de Winkel JG, Ernst LK, Anderson CL, Chiu IM. Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene. J Biol Chem 1991;266:13449-13455.
-
(1991)
J Biol Chem
, vol.266
, pp. 13449-13455
-
-
van de Winkel, J.G.1
Ernst, L.K.2
Anderson, C.L.3
Chiu, I.M.4
-
46
-
-
0016713311
-
Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages
-
Unkeless JC, Eisen HN. Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages. J Exp Med 1975;142:1520-1533.
-
(1975)
J Exp Med
, vol.142
, pp. 1520-1533
-
-
Unkeless, J.C.1
Eisen, H.N.2
-
47
-
-
84871105419
-
Cutting edge: FcgammaRIII (CD16) and FcgammaRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma
-
Albanesi M, et al. Cutting edge: FcgammaRIII (CD16) and FcgammaRI (CD64) are responsible for anti-glycoprotein 75 monoclonal antibody TA99 therapy for experimental metastatic B16 melanoma. J Immunol 2012;189:5513-5517.
-
(2012)
J Immunol
, vol.189
, pp. 5513-5517
-
-
Albanesi, M.1
-
48
-
-
84876463158
-
The high-affinity human IgG receptor Fc gamma RI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy
-
Mancardi DA, et al. The high-affinity human IgG receptor Fc gamma RI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy. Blood 2013;121:1563-1573.
-
(2013)
Blood
, vol.121
, pp. 1563-1573
-
-
Mancardi, D.A.1
-
49
-
-
84867428535
-
Pentraxins and Fc receptors
-
Lu J, Marjon KD, Mold C, Du Clos TW, Sun PD. Pentraxins and Fc receptors. Immunol Rev 2012;250:230-238.
-
(2012)
Immunol Rev
, vol.250
, pp. 230-238
-
-
Lu, J.1
Marjon, K.D.2
Mold, C.3
Du Clos, T.W.4
Sun, P.D.5
-
50
-
-
57749172475
-
Structural recognition and functional activation of FcgammaR by innate pentraxins
-
Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD. Structural recognition and functional activation of FcgammaR by innate pentraxins. Nature 2008;456:989-992.
-
(2008)
Nature
, vol.456
, pp. 989-992
-
-
Lu, J.1
Marnell, L.L.2
Marjon, K.D.3
Mold, C.4
Du Clos, T.W.5
Sun, P.D.6
-
51
-
-
77952887713
-
The SYK tyrosine kinase: a crucial player in diverse biological functions
-
Mocsai A, Ruland J, Tybulewicz VL. The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat Rev Immunol 2010;10:387-402.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 387-402
-
-
Mocsai, A.1
Ruland, J.2
Tybulewicz, V.L.3
-
52
-
-
69149095639
-
The role of Tec family kinases in mononuclear phagocytes
-
Koprulu AD, Ellmeier W. The role of Tec family kinases in mononuclear phagocytes. Crit Rev Immunol 2009;29:317-333.
-
(2009)
Crit Rev Immunol
, vol.29
, pp. 317-333
-
-
Koprulu, A.D.1
Ellmeier, W.2
-
53
-
-
0033569768
-
The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complex
-
Edberg JC, et al. The cytoplasmic domain of human FcgammaRIa alters the functional properties of the FcgammaRI.gamma-chain receptor complex. J Biol Chem 1999;274:30328-30333.
-
(1999)
J Biol Chem
, vol.274
, pp. 30328-30333
-
-
Edberg, J.C.1
-
54
-
-
38949173224
-
Protein 4.1G binds to a unique motif within the Fc gamma RI cytoplasmic tail
-
Beekman JM, Bakema JE, van der Poel CE, van der Linden JA, van de Winkel JG, Leusen JH. Protein 4.1G binds to a unique motif within the Fc gamma RI cytoplasmic tail. Mol Immunol 2008;45:2069-2075.
-
(2008)
Mol Immunol
, vol.45
, pp. 2069-2075
-
-
Beekman, J.M.1
Bakema, J.E.2
van der Poel, C.E.3
van der Linden, J.A.4
van de Winkel, J.G.5
Leusen, J.H.6
-
55
-
-
84867911797
-
The unique cytoplasmic domain of human FcgammaRIIIA regulates receptor-mediated function
-
Li X, et al. The unique cytoplasmic domain of human FcgammaRIIIA regulates receptor-mediated function. J Immunol 2012;189:4284-4294.
-
(2012)
J Immunol
, vol.189
, pp. 4284-4294
-
-
Li, X.1
-
56
-
-
44849121489
-
Filamin A stabilizes Fc gamma RI surface expression and prevents its lysosomal routing
-
Beekman JM, et al. Filamin A stabilizes Fc gamma RI surface expression and prevents its lysosomal routing. J Immunol 2008;180:3938-3945.
-
(2008)
J Immunol
, vol.180
, pp. 3938-3945
-
-
Beekman, J.M.1
-
57
-
-
0027940129
-
Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis
-
Harrison PT, Davis W, Norman JC, Hockaday AR, Allen JM. Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis. J Biol Chem 1994;269:24396-24402.
-
(1994)
J Biol Chem
, vol.269
, pp. 24396-24402
-
-
Harrison, P.T.1
Davis, W.2
Norman, J.C.3
Hockaday, A.R.4
Allen, J.M.5
-
58
-
-
3142685132
-
Direct interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity
-
Beekman JM, Bakema JE, van de Winkel JG, Leusen JH. Direct interaction between FcgammaRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity. Proc Natl Acad Sci USA 2004;101:10392-10397.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10392-10397
-
-
Beekman, J.M.1
Bakema, J.E.2
van de Winkel, J.G.3
Leusen, J.H.4
-
59
-
-
0033564979
-
The Fc gamma RIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain
-
van Vugt MJ, et al. The Fc gamma RIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain. Blood 1999;94:808-817.
-
(1999)
Blood
, vol.94
, pp. 808-817
-
-
van Vugt, M.J.1
-
60
-
-
4043133804
-
Modulation of FcgammaRI (CD64) ligand binding by blocking peptides of periplakin
-
Beekman JM, et al. Modulation of FcgammaRI (CD64) ligand binding by blocking peptides of periplakin. J Biol Chem 2004;279:33875-33881.
-
(2004)
J Biol Chem
, vol.279
, pp. 33875-33881
-
-
Beekman, J.M.1
-
61
-
-
0015406349
-
Macrophages in syngeneic animal tumours
-
Evans R. Macrophages in syngeneic animal tumours. Transplantation 1972;14:468-473.
-
(1972)
Transplantation
, vol.14
, pp. 468-473
-
-
Evans, R.1
-
62
-
-
0017103726
-
Humoral factors influencing lymphocyte transformation
-
Nelson DS, Gatti RA. Humoral factors influencing lymphocyte transformation. Prog Allergy 1976;21:261-341.
-
(1976)
Prog Allergy
, vol.21
, pp. 261-341
-
-
Nelson, D.S.1
Gatti, R.A.2
-
63
-
-
0017741071
-
Macrophage tumor killing: influence of the local environment
-
Hibbs JB Jr, Taintor RR, Chapman HA Jr, Weinberg JB. Macrophage tumor killing: influence of the local environment. Science 1977;197:279-282.
-
(1977)
Science
, vol.197
, pp. 279-282
-
-
Hibbs, J.B.1
Taintor, R.R.2
Chapman, H.A.3
Weinberg, J.B.4
-
64
-
-
0017739229
-
Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect
-
Weinberg JB, Hibbs JB Jr. Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect. Nature 1977;269:245-247.
-
(1977)
Nature
, vol.269
, pp. 245-247
-
-
Weinberg, J.B.1
Hibbs, J.B.2
-
65
-
-
0020520274
-
Inhibition of macrophage tumoricidal activity by immune complexes and altered erythrocytes
-
Esparza I, Green R, Schreiber RD. Inhibition of macrophage tumoricidal activity by immune complexes and altered erythrocytes. J Immunol 1983;131:2117-2121.
-
(1983)
J Immunol
, vol.131
, pp. 2117-2121
-
-
Esparza, I.1
Green, R.2
Schreiber, R.D.3
-
66
-
-
0028833563
-
IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor
-
Feldman GM, Chuang EJ, Finbloom DS. IgG immune complexes inhibit IFN-gamma-induced transcription of the Fc gamma RI gene in human monocytes by preventing the tyrosine phosphorylation of the p91 (Stat1) transcription factor. J Immunol 1995;154:318-325.
-
(1995)
J Immunol
, vol.154
, pp. 318-325
-
-
Feldman, G.M.1
Chuang, E.J.2
Finbloom, D.S.3
-
67
-
-
33947678731
-
Immune complexes suppress IFN-gamma signaling by activation of the FcgammaRI pathway
-
Boekhoudt GH, Frazier-Jessen MR, Feldman GM. Immune complexes suppress IFN-gamma signaling by activation of the FcgammaRI pathway. J Leukoc Biol 2007;81:1086-1092.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 1086-1092
-
-
Boekhoudt, G.H.1
Frazier-Jessen, M.R.2
Feldman, G.M.3
-
68
-
-
84921482984
-
Immune complexes suppress IFN-gamma-induced responses in monocytes by activating discrete members of the SRC kinase family
-
Boekhoudt GH, McGrath AG, Swisher JF, Feldman GM. Immune complexes suppress IFN-gamma-induced responses in monocytes by activating discrete members of the SRC kinase family. J Immunol 2015;194:983-989.
-
(2015)
J Immunol
, vol.194
, pp. 983-989
-
-
Boekhoudt, G.H.1
McGrath, A.G.2
Swisher, J.F.3
Feldman, G.M.4
-
69
-
-
84920863627
-
IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcgammaRI
-
Swisher JF, Haddad DA, McGrath AG, Boekhoudt GH, Feldman GM. IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through FcgammaRI. mAbs 2014;6:1377-1384.
-
(2014)
mAbs
, vol.6
, pp. 1377-1384
-
-
Swisher, J.F.1
Haddad, D.A.2
McGrath, A.G.3
Boekhoudt, G.H.4
Feldman, G.M.5
-
70
-
-
0029970787
-
Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor
-
Kimura T, Kihara H, Bhattacharyya S, Sakamoto H, Appella E, Siraganian RP. Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor. J Biol Chem 1996;271:27962-27968.
-
(1996)
J Biol Chem
, vol.271
, pp. 27962-27968
-
-
Kimura, T.1
Kihara, H.2
Bhattacharyya, S.3
Sakamoto, H.4
Appella, E.5
Siraganian, R.P.6
-
71
-
-
0029864882
-
Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides
-
Kimura T, Sakamoto H, Appella E, Siraganian RP. Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides. Mol Cell Biol 1996;16:1471-1478.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1471-1478
-
-
Kimura, T.1
Sakamoto, H.2
Appella, E.3
Siraganian, R.P.4
-
72
-
-
84905163957
-
Role of FcgammaRIIIA (CD16) in IVIg-mediated anti-inflammatory function
-
Ben Mkaddem S, Aloulou M, Benhamou M, Monteiro RC. Role of FcgammaRIIIA (CD16) in IVIg-mediated anti-inflammatory function. J Clin Immunol 2014;34(Suppl.):S46-S50.
-
(2014)
J Clin Immunol
, vol.34
, pp. S46-S50
-
-
Ben Mkaddem, S.1
Aloulou, M.2
Benhamou, M.3
Monteiro, R.C.4
-
73
-
-
84907008496
-
Shifting FcgammaRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis
-
Ben Mkaddem S, et al. Shifting FcgammaRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis. J Clin Invest 2014;124:3945-3959.
-
(2014)
J Clin Invest
, vol.124
, pp. 3945-3959
-
-
Ben Mkaddem, S.1
-
75
-
-
79954988275
-
How ITAMs inhibit signaling
-
Ivashkiv LB. How ITAMs inhibit signaling. Sci Signal 2011;4:pe20.
-
(2011)
Sci Signal
, vol.4
, pp. pe20
-
-
Ivashkiv, L.B.1
-
76
-
-
77957016117
-
The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production
-
Gallo P, Goncalves R, Mosser DM. The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production. Immunol Lett 2010;133:70-77.
-
(2010)
Immunol Lett
, vol.133
, pp. 70-77
-
-
Gallo, P.1
Goncalves, R.2
Mosser, D.M.3
-
77
-
-
67651095947
-
Differential signal transduction, membrane trafficking, and immune effector functions mediated by Fc gamma RI versus Fc gamma RIIa
-
Dai XL, et al. Differential signal transduction, membrane trafficking, and immune effector functions mediated by Fc gamma RI versus Fc gamma RIIa. Blood 2009;114:318-327.
-
(2009)
Blood
, vol.114
, pp. 318-327
-
-
Dai, X.L.1
-
78
-
-
0037606153
-
Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis
-
Ji JD, et al. Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis. J Exp Med 2003;197:1573-1583.
-
(2003)
J Exp Med
, vol.197
, pp. 1573-1583
-
-
Ji, J.D.1
-
79
-
-
84896647364
-
A role for the ITAM signaling module in specifying cytokine-receptor functions
-
Bezbradica JS, Rosenstein RK, Demarco RA, Brodsky I, Medzhitov R. A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol 2014;15:333-342.
-
(2014)
Nat Immunol
, vol.15
, pp. 333-342
-
-
Bezbradica, J.S.1
Rosenstein, R.K.2
Demarco, R.A.3
Brodsky, I.4
Medzhitov, R.5
-
80
-
-
18344370440
-
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection
-
Ioan-Facsinay A, et al. FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 2002;16:391-402.
-
(2002)
Immunity
, vol.16
, pp. 391-402
-
-
Ioan-Facsinay, A.1
-
81
-
-
0032490575
-
Reversal of proinflammatory responses by ligating the macrophage Fc gamma receptor type I
-
Sutterwala FS, Noel GJ, Salgame P, Mosser DM. Reversal of proinflammatory responses by ligating the macrophage Fc gamma receptor type I. J Exp Med 1998;188:217-222.
-
(1998)
J Exp Med
, vol.188
, pp. 217-222
-
-
Sutterwala, F.S.1
Noel, G.J.2
Salgame, P.3
Mosser, D.M.4
-
82
-
-
84874275259
-
FcalphaRI-mediated inhibition of IL-12 production and priming by IFN-gamma of human monocytes and dendritic cells
-
Lecocq M, Detry B, Guisset A, Pilette C. FcalphaRI-mediated inhibition of IL-12 production and priming by IFN-gamma of human monocytes and dendritic cells. J Immunol 2013;190:2362-2371.
-
(2013)
J Immunol
, vol.190
, pp. 2362-2371
-
-
Lecocq, M.1
Detry, B.2
Guisset, A.3
Pilette, C.4
-
83
-
-
84926664616
-
Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages
-
Vogelpoel LT, et al. Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages. Nat Commun 2014;5:5444.
-
(2014)
Nat Commun
, vol.5
, pp. 5444
-
-
Vogelpoel, L.T.1
-
84
-
-
0030803892
-
High levels of cerebrospinal fluid IgM binding to myelin basic protein are associated with early benign course in multiple sclerosis
-
Annunziata P, Pluchino S, Martino T, Guazzi G. High levels of cerebrospinal fluid IgM binding to myelin basic protein are associated with early benign course in multiple sclerosis. J Neuroimmunol 1997;77:128-133.
-
(1997)
J Neuroimmunol
, vol.77
, pp. 128-133
-
-
Annunziata, P.1
Pluchino, S.2
Martino, T.3
Guazzi, G.4
-
85
-
-
84875364108
-
Immunosuppressive monoclonal antibody to CD64 from patients with long-term stable multiple sclerosis
-
Annunziata P, Cioni C, Cantalupo L, Di Genova G, Savellini GG, Cusi G. Immunosuppressive monoclonal antibody to CD64 from patients with long-term stable multiple sclerosis. J Neuroimmunol 2013;256:62-70.
-
(2013)
J Neuroimmunol
, vol.256
, pp. 62-70
-
-
Annunziata, P.1
Cioni, C.2
Cantalupo, L.3
Di Genova, G.4
Savellini, G.G.5
Cusi, G.6
-
86
-
-
0025370870
-
T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
-
Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990;346:183-187.
-
(1990)
Nature
, vol.346
, pp. 183-187
-
-
Ota, K.1
Matsui, M.2
Milford, E.L.3
Mackin, G.A.4
Weiner, H.L.5
Hafler, D.A.6
-
87
-
-
77951523463
-
Bispecific antibodies for cancer therapy: the light at the end of the tunnel?
-
Chames P, Baty D. Bispecific antibodies for cancer therapy: the light at the end of the tunnel? mAbs 2009;1:539-547.
-
(2009)
mAbs
, vol.1
, pp. 539-547
-
-
Chames, P.1
Baty, D.2
-
88
-
-
77957160633
-
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
-
Halstead SB, Mahalingam S, Marovich MA, Ubol S, Mosser DM. Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes. Lancet Infect Dis 2010;10:712-722.
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 712-722
-
-
Halstead, S.B.1
Mahalingam, S.2
Marovich, M.A.3
Ubol, S.4
Mosser, D.M.5
-
89
-
-
33749454503
-
Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32)
-
Rodrigo WW, Jin X, Blackley SD, Rose RC, Schlesinger JJ. Differential enhancement of dengue virus immune complex infectivity mediated by signaling-competent and signaling-incompetent human Fcgamma RIA (CD64) or FcgammaRIIA (CD32). J Virol 2006;80:10128-10138.
-
(2006)
J Virol
, vol.80
, pp. 10128-10138
-
-
Rodrigo, W.W.1
Jin, X.2
Blackley, S.D.3
Rose, R.C.4
Schlesinger, J.J.5
-
90
-
-
84923052917
-
Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection
-
Yamada DH, et al. Suppression of Fcgamma-receptor-mediated antibody effector function during persistent viral infection. Immunity 2015;42:379-390.
-
(2015)
Immunity
, vol.42
, pp. 379-390
-
-
Yamada, D.H.1
-
91
-
-
84922970995
-
Antibody effector functions mediated by Fcgamma-receptors are compromised during persistent viral infection
-
Wieland A, et al. Antibody effector functions mediated by Fcgamma-receptors are compromised during persistent viral infection. Immunity 2015;42:367-378.
-
(2015)
Immunity
, vol.42
, pp. 367-378
-
-
Wieland, A.1
-
92
-
-
15444364277
-
A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
-
Miles SA, Conrad SM, Alves RG, Jeronimo SM, Mosser DM. A role for IgG immune complexes during infection with the intracellular pathogen Leishmania. J Exp Med 2005;201:747-754.
-
(2005)
J Exp Med
, vol.201
, pp. 747-754
-
-
Miles, S.A.1
Conrad, S.M.2
Alves, R.G.3
Jeronimo, S.M.4
Mosser, D.M.5
-
93
-
-
84945283981
-
Challenging the Th1 paradigm: a detrimental role for IFN-gamma and IFN-regulated CD64 in human leishmaniasis
-
Van Weyenbergh J, et al. Challenging the Th1 paradigm: a detrimental role for IFN-gamma and IFN-regulated CD64 in human leishmaniasis. Cytokine 2013;63:306.
-
(2013)
Cytokine
, vol.63
, pp. 306
-
-
Van Weyenbergh, J.1
-
94
-
-
13444306169
-
Reversal of ongoing proteinuria in autoimmune mice by treatment with C-reactive protein
-
Rodriguez W, Mold C, Kataranovski M, Hutt J, Marnell LL, Du Clos TW. Reversal of ongoing proteinuria in autoimmune mice by treatment with C-reactive protein. Arthritis Rheum 2005;52:642-650.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 642-650
-
-
Rodriguez, W.1
Mold, C.2
Kataranovski, M.3
Hutt, J.4
Marnell, L.L.5
Du Clos, T.W.6
-
95
-
-
0038798080
-
Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene
-
Szalai AJ, et al. Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene. Arthritis Rheum 2003;48:1602-1611.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 1602-1611
-
-
Szalai, A.J.1
-
96
-
-
31044446853
-
Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein
-
Rodriguez W, et al. Prevention and reversal of nephritis in MRL/lpr mice with a single injection of C-reactive protein. Arthritis Rheum 2006;54:325-335.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 325-335
-
-
Rodriguez, W.1
-
97
-
-
84929625543
-
C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis
-
Zhang L, et al. C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis. J Immunol 2015;194:5243-5252.
-
(2015)
J Immunol
, vol.194
, pp. 5243-5252
-
-
Zhang, L.1
-
98
-
-
0037114170
-
C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R
-
Mold C, Rodriguez W, Rodic-Polic B, Du Clos TW. C-reactive protein mediates protection from lipopolysaccharide through interactions with Fc gamma R. J Immunol 2002;169:7019-7025.
-
(2002)
J Immunol
, vol.169
, pp. 7019-7025
-
-
Mold, C.1
Rodriguez, W.2
Rodic-Polic, B.3
Du Clos, T.W.4
-
99
-
-
63149133894
-
Macrophages activated by C-reactive protein through Fc gamma RI transfer suppression of immune thrombocytopenia
-
Marjon KD, Marnell LL, Mold C, Du Clos TW. Macrophages activated by C-reactive protein through Fc gamma RI transfer suppression of immune thrombocytopenia. J Immunol 2009;182:1397-1403.
-
(2009)
J Immunol
, vol.182
, pp. 1397-1403
-
-
Marjon, K.D.1
Marnell, L.L.2
Mold, C.3
Du Clos, T.W.4
-
100
-
-
84868117632
-
FcgammaRI mediates serum amyloid P inhibition of fibrocyte differentiation
-
Crawford JR, Pilling D, Gomer RH. FcgammaRI mediates serum amyloid P inhibition of fibrocyte differentiation. J Leukoc Biol 2012;92:699-711.
-
(2012)
J Leukoc Biol
, vol.92
, pp. 699-711
-
-
Crawford, J.R.1
Pilling, D.2
Gomer, R.H.3
-
101
-
-
84905058971
-
Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcgammaRI
-
Pilling D, Crawford JR, Verbeek JS, Gomer RH. Inhibition of murine fibrocyte differentiation by cross-linked IgG is dependent on FcgammaRI. J Leukoc Biol 2014;96:275-282.
-
(2014)
J Leukoc Biol
, vol.96
, pp. 275-282
-
-
Pilling, D.1
Crawford, J.R.2
Verbeek, J.S.3
Gomer, R.H.4
-
102
-
-
84925061777
-
The long pentraxin PTX3 promotes fibrocyte differentiation
-
Pilling D, Cox N, Vakil V, Verbeek JS, Gomer RH. The long pentraxin PTX3 promotes fibrocyte differentiation. PLoS ONE 2015;10:e0119709.
-
(2015)
PLoS ONE
, vol.10
, pp. e0119709
-
-
Pilling, D.1
Cox, N.2
Vakil, V.3
Verbeek, J.S.4
Gomer, R.H.5
-
103
-
-
84924602786
-
Macrophages are critical effectors of antibody therapies for cancer
-
Weiskopf K, Weissman IL. Macrophages are critical effectors of antibody therapies for cancer. mAbs 2015;7:303-310.
-
(2015)
mAbs
, vol.7
, pp. 303-310
-
-
Weiskopf, K.1
Weissman, I.L.2
-
104
-
-
84867055822
-
Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases
-
Hristodorov D, Mladenov R, Huhn M, Barth S, Thepen T. Macrophage-targeted therapy: CD64-based immunotoxins for treatment of chronic inflammatory diseases. Toxins (Basel) 2012;4:676-694.
-
(2012)
Toxins (Basel)
, vol.4
, pp. 676-694
-
-
Hristodorov, D.1
Mladenov, R.2
Huhn, M.3
Barth, S.4
Thepen, T.5
-
105
-
-
38549176118
-
Tumor necrosis factor antagonist mechanisms of action: a comprehensive review
-
Tracey D, Klareskog L, Sasso EH, Salfeld JG, Tak PP. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther 2008;117:244-279.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 244-279
-
-
Tracey, D.1
Klareskog, L.2
Sasso, E.H.3
Salfeld, J.G.4
Tak, P.P.5
-
106
-
-
84908270911
-
Dysregulated Fc receptor function in active rheumatoid arthritis
-
Magnusson SE, Wennerberg E, Matt P, Lindqvist U, Kleinau S. Dysregulated Fc receptor function in active rheumatoid arthritis. Immunol Lett 2014;162:200-206.
-
(2014)
Immunol Lett
, vol.162
, pp. 200-206
-
-
Magnusson, S.E.1
Wennerberg, E.2
Matt, P.3
Lindqvist, U.4
Kleinau, S.5
-
107
-
-
78650459480
-
Anti-tumor necrosis factor-alpha antibodies induce regulatory macrophages in an Fc region-dependent manner
-
Vos AC, Wildenberg ME, Duijvestein M, Verhaar AP, van den Brink GR, Hommes DW. Anti-tumor necrosis factor-alpha antibodies induce regulatory macrophages in an Fc region-dependent manner. Gastroenterology 2011;140:221-230.
-
(2011)
Gastroenterology
, vol.140
, pp. 221-230
-
-
Vos, A.C.1
Wildenberg, M.E.2
Duijvestein, M.3
Verhaar, A.P.4
van den Brink, G.R.5
Hommes, D.W.6
-
108
-
-
84857373545
-
Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro
-
Vos AC, et al. Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro. Inflamm Bowel Dis 2012;18:401-408.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 401-408
-
-
Vos, A.C.1
-
109
-
-
84905380032
-
Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient mice
-
Zhang H, et al. Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient mice. World J Gastroenterol 2014;20:9106-9115.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 9106-9115
-
-
Zhang, H.1
-
110
-
-
33744933432
-
A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease
-
Braat H, et al. A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's disease. Clin Gastroenterol Hepatol 2006;4:754-759.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 754-759
-
-
Braat, H.1
-
111
-
-
84896117860
-
In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease
-
Atreya R, et al. In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease. Nat Med 2014;20:313-318.
-
(2014)
Nat Med
, vol.20
, pp. 313-318
-
-
Atreya, R.1
-
112
-
-
84913591914
-
Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy
-
Hristodorov D, Mladenov R, Brehm H, Fischer R, Barth S, Thepen T. Recombinant H22(scFv) blocks CD64 and prevents the capture of anti-TNF monoclonal antibody. A potential strategy to enhance anti-TNF therapy. mAbs 2014;6:1283-1289.
-
(2014)
mAbs
, vol.6
, pp. 1283-1289
-
-
Hristodorov, D.1
Mladenov, R.2
Brehm, H.3
Fischer, R.4
Barth, S.5
Thepen, T.6
-
113
-
-
84871770952
-
A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer
-
Mellor JD, Brown MP, Irving HR, Zalcberg JR, Dobrovic A. A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer. J Hematol Oncol 2013;6:1.
-
(2013)
J Hematol Oncol
, vol.6
, pp. 1
-
-
Mellor, J.D.1
Brown, M.P.2
Irving, H.R.3
Zalcberg, J.R.4
Dobrovic, A.5
-
114
-
-
0027304602
-
Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy
-
Valerius T, et al. Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy. Blood 1993;82:931-939.
-
(1993)
Blood
, vol.82
, pp. 931-939
-
-
Valerius, T.1
-
115
-
-
0031905710
-
Fc receptors are required in passive and active immunity to melanoma
-
Clynes R, Takechi Y, Moroi Y, Houghton A, Ravetch JV. Fc receptors are required in passive and active immunity to melanoma. Proc Natl Acad Sci USA 1998;95:652-656.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 652-656
-
-
Clynes, R.1
Takechi, Y.2
Moroi, Y.3
Houghton, A.4
Ravetch, J.V.5
-
116
-
-
32944454324
-
The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma
-
Bevaart L, Jansen MJ, van Vugt MJ, Verbeek JS, van de Winkel JG, Leusen JH. The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma. Cancer Res 2006;66:1261-1264.
-
(2006)
Cancer Res
, vol.66
, pp. 1261-1264
-
-
Bevaart, L.1
Jansen, M.J.2
van Vugt, M.J.3
Verbeek, J.S.4
van de Winkel, J.G.5
Leusen, J.H.6
-
117
-
-
77956262454
-
Experimentally induced liver metastases from colorectal cancer can be prevented by mononuclear phagocyte-mediated monoclonal antibody therapy
-
van der Bij GJ, et al. Experimentally induced liver metastases from colorectal cancer can be prevented by mononuclear phagocyte-mediated monoclonal antibody therapy. J Hepatol 2010;53:677-685.
-
(2010)
J Hepatol
, vol.53
, pp. 677-685
-
-
van der Bij, G.J.1
-
118
-
-
58149198794
-
Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV
-
Otten MA, et al. Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV. J Immunol 2008;181:6829-6836.
-
(2008)
J Immunol
, vol.181
, pp. 6829-6836
-
-
Otten, M.A.1
-
119
-
-
84902548351
-
Anti-tumor activity of human IgG1 anti-gp75 TA99 mAb against B16F10 melanoma in human FcgammaRI transgenic mice
-
Boross P, et al. Anti-tumor activity of human IgG1 anti-gp75 TA99 mAb against B16F10 melanoma in human FcgammaRI transgenic mice. Immunol Lett 2014;160:151-157.
-
(2014)
Immunol Lett
, vol.160
, pp. 151-157
-
-
Boross, P.1
-
120
-
-
77955600434
-
Regulation of angiogenesis by macrophages
-
Apte RS. Regulation of angiogenesis by macrophages. Adv Exp Med Biol 2010;664:15-19.
-
(2010)
Adv Exp Med Biol
, vol.664
, pp. 15-19
-
-
Apte, R.S.1
-
121
-
-
0036839143
-
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002;23:549-555.
-
(2002)
Trends Immunol
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
122
-
-
33845524204
-
Role of tumor-associated macrophages in tumor progression and invasion
-
Mantovani A, Schioppa T, Porta C, Allavena P, Sica A. Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev 2006;25:315-322.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 315-322
-
-
Mantovani, A.1
Schioppa, T.2
Porta, C.3
Allavena, P.4
Sica, A.5
-
123
-
-
80052490775
-
Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab
-
Pander J, et al. Activation of tumor-promoting type 2 macrophages by EGFR-targeting antibody cetuximab. Clin Cancer Res 2011;17:5668-5673.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5668-5673
-
-
Pander, J.1
-
124
-
-
84921916858
-
Tumor-associated macrophages as an emerging target against tumors: creating a new path from bench to bedside
-
Jinushi M, Komohara Y. Tumor-associated macrophages as an emerging target against tumors: creating a new path from bench to bedside. Biochim Biophys Acta 2015;1855:123-130.
-
(2015)
Biochim Biophys Acta
, vol.1855
, pp. 123-130
-
-
Jinushi, M.1
Komohara, Y.2
-
125
-
-
84885205350
-
Targeting tumor-infiltrating macrophages to combat cancer
-
Panni RZ, Linehan DC, DeNardo DG. Targeting tumor-infiltrating macrophages to combat cancer. Immunother UK 2013;5:1075-1087.
-
(2013)
Immunother UK
, vol.5
, pp. 1075-1087
-
-
Panni, R.Z.1
Linehan, D.C.2
DeNardo, D.G.3
-
126
-
-
84869856891
-
Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function
-
Grugan KD, et al. Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function. J Immunol 2012;189:5457-5466.
-
(2012)
J Immunol
, vol.189
, pp. 5457-5466
-
-
Grugan, K.D.1
-
127
-
-
35348843627
-
A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone
-
Taskinen M, Karjalainen-Lindsberg ML, Nyman H, Eerola LM, Leppa S. A high tumor-associated macrophage content predicts favorable outcome in follicular lymphoma patients treated with rituximab and cyclophosphamide-doxorubicin-vincristine-prednisone. Clin Cancer Res 2007;13:5784-5789.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5784-5789
-
-
Taskinen, M.1
Karjalainen-Lindsberg, M.L.2
Nyman, H.3
Eerola, L.M.4
Leppa, S.5
-
128
-
-
38649108461
-
High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial
-
Canioni D, et al. High numbers of tumor-associated macrophages have an adverse prognostic value that can be circumvented by rituximab in patients with follicular lymphoma enrolled onto the GELA-GOELAMS FL-2000 trial. J Clin Oncol 2008;26:440-446.
-
(2008)
J Clin Oncol
, vol.26
, pp. 440-446
-
-
Canioni, D.1
-
129
-
-
84977126665
-
The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer
-
Stewart R, Hammond SA, Oberst M, Wilkinson RW. The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer. J Immunother Cancer 2014;2:29-38.
-
(2014)
J Immunother Cancer
, vol.2
, pp. 29-38
-
-
Stewart, R.1
Hammond, S.A.2
Oberst, M.3
Wilkinson, R.W.4
-
130
-
-
79551575923
-
Advances in the assessment and control of the effector functions of therapeutic antibodies
-
Jiang XR, et al. Advances in the assessment and control of the effector functions of therapeutic antibodies. Nat Rev Drug Discov 2011;10:101-111.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 101-111
-
-
Jiang, X.R.1
-
131
-
-
0027456571
-
Structural motifs involved in human IgG antibody effector functions
-
Greenwood J, Clark M, Waldmann H. Structural motifs involved in human IgG antibody effector functions. Eur J Immunol 1993;23:1098-1104.
-
(1993)
Eur J Immunol
, vol.23
, pp. 1098-1104
-
-
Greenwood, J.1
Clark, M.2
Waldmann, H.3
-
132
-
-
0029852737
-
A therapeutic human IgG4 monoclonal antibody that depletes target cells in humans
-
Isaacs JD, Wing MG, Greenwood JD, Hazleman BL, Hale G, Waldmann H. A therapeutic human IgG4 monoclonal antibody that depletes target cells in humans. Clin Exp Immunol 1996;106:427-433.
-
(1996)
Clin Exp Immunol
, vol.106
, pp. 427-433
-
-
Isaacs, J.D.1
Wing, M.G.2
Greenwood, J.D.3
Hazleman, B.L.4
Hale, G.5
Waldmann, H.6
-
133
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
Suntharalingam G, et al. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med 2006;355:1018-1028.
-
(2006)
N Engl J Med
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
-
134
-
-
84896514032
-
+ immune cells contribute to the TGN1412-triggered cytokine response
-
+ immune cells contribute to the TGN1412-triggered cytokine response. J Immunol 2014;192:2091-2098.
-
(2014)
J Immunol
, vol.192
, pp. 2091-2098
-
-
Bartholomaeus, P.1
-
135
-
-
84871122818
-
Antibody C region influences TGN1412-like functional activity in vitro
-
Ball C, et al. Antibody C region influences TGN1412-like functional activity in vitro. J Immunol 2012;189:5831-5840.
-
(2012)
J Immunol
, vol.189
, pp. 5831-5840
-
-
Ball, C.1
-
136
-
-
84898045276
-
A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity
-
Lux A, et al. A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity. Cell Rep 2014;7:236-248.
-
(2014)
Cell Rep
, vol.7
, pp. 236-248
-
-
Lux, A.1
-
137
-
-
84904394690
-
Macrophage activation and polarization: nomenclature and experimental guidelines
-
Murray PJ, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 2014;41:14-20.
-
(2014)
Immunity
, vol.41
, pp. 14-20
-
-
Murray, P.J.1
|