Neutrophil CD64 expression is elevated in acetaminophen-induced acute liver failure

American Journal of Respiratory and Critical Care Medicine

Volumn 186, Issue 10, 2012, Pages 1058-1059

  Abeles, Robin Daniel ^a   Taylor, Nicholas J ^a   Manakkat Vijay, Godhev K ^a   Ryan, Jennifer ^a   Tranah, Thomas H ^a   Bernal, William ^a   Wendon, Julia A ^a   Shawcross, Debbie L ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD64 ANTIGEN; PARACETAMOL;

ACUTE LIVER FAILURE; CRITICALLY ILL PATIENT; DRUG INTOXICATION; HUMAN; LETTER; LIVER TRANSPLANTATION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; SEPSIS;

EID: 84869224881     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/ajrccm.186.10.1058a     Document Type: Letter

References (6)

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2. Hoffmann JJ. Neutrophil CD64: a diagnostic marker for infection and sepsis. Clin Chem Lab Med 2009;47:903-916.
3. Gros A, Roussel M, Sauvadet E, Gacouin A, Marqué S, Chimot L, Lavoué S, Camus C, Fest T, Le Tulzo Y. The sensitivity of neutrophil CD64 expression as a biomarker of bacterial infection is low in critically ill patients. Intensive Care Med 2012;38:445-452.
4. Antoniades CG, Berry PA, Wendon JA, Vergani D. The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol 2008;49:845-861.
5. Rolando N, Wade J, Davalos M, Wendon J, Philpott-Howard J, Williams R. The systemic inflammatory response syndrome in acute liver failure. Hepatology 2000;32:734-739.
6. Abeles RD, McPhail MJ, Sowter D, Antoniades CG, Vergis N, Vijay GK, Xystrakis E, Khamri W, Shawcross DL, Ma Y, et al. CD14, CD16 and HLA-DR reliably identifies human monocytes and their subsets in the context of pathologically reduced HLA-DR expression by CD14(hi)/CD16 (neg) monocytes: expansion of CD14(hi)/CD16(pos) and contraction of CD14(lo)/CD16(pos) monocytes in acute liver failure. Cytometry A 2012.