Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

Journal of Clinical Investigation

Volumn 124, Issue 9, 2014, Pages 3945-3959

  Mkaddem, Sanae Ben ^a,b,c,d   Hayem, Gilles ^d   Jönsson, Friederike ^a,e   Rossato, Elisabetta ^a,b,c,d   Boedec, Erwan ^a,b,c,d   Boussetta, Tarek ^a,b,c,d   El Benna, Jamel ^a,b,c,d   Launay, Pierre ^a,b,c,d   Goujon, Jean Michel ^f   Benhamou, Marc ^a,b,c,d   Bruhns, Pierre ^a,e   Monteiro, Renato C ^a,b,c,d  

^a INSERM   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d BICHAT HOSPITAL   (France)

^e INSTITUT PASTEUR   (France)

^f POITIERS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR IIA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR VAV 1; IMMUNOGLOBULIN F(AB')2 FRAGMENT; IMMUNOGLOBULIN G; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; PROTEIN KINASE SYK; PROTEIN TYROSINE PHOSPHATASE SHP 1; REACTIVE OXYGEN METABOLITE; TYROSINE; UNCLASSIFIED DRUG; FC RECEPTOR; FCGR2B PROTEIN, MOUSE; IMMUNOGLOBULIN; PROTEIN TYROSINE KINASE; PTPN6 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ALLOTYPE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EDEMA; ERYTHEMA; FEMALE; HUMAN; HUMAN CELL; HYPERPLASIA; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; IMMUNOTHERAPY; INFLAMMATION; INFLAMMATORY CELL; MOUSE; NONHUMAN; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIAL FLUID; SYNOVIOCYTE; ANIMAL; ARTHRITIS, RHEUMATOID; C57BL MOUSE; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ARTHRITIS, RHEUMATOID; FEMALE; IMMUNOGLOBULINS, INTRAVENOUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; RECEPTORS, IGG; SIGNAL TRANSDUCTION;

EID: 84907008496     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI74572     Document Type: Article

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