1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cells

Free Radical Biology and Medicine

Volumn 89, Issue , 2015, Pages 831-841

  Tanaka, Yuki ^a   Kume, Shinji ^a   Araki, Hisazumi ^a   Nakazawa, Jun ^a   Chin Kanasaki, Masami ^a   Araki, Shin Ichi ^a   Nakagawa, Fumiyuki ^a,b   Koya, Daisuke ^c   Haneda, Masakazu ^d   Maegawa, Hiroshi ^a   Uzu, Takashi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b CMIC Pharma Science Co   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

^d ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Apoptosis; Lipotoxicity; Necrosis; Nicotinamide adenine dinucleotide(NAD); Nicotinamide N methyltransferase(NNMT); Proteinuria; Proximal tubular cell damage

Indexed keywords

1 METHYLNICOTINAMIDE; ALBUMIN; FATTY ACID; MESSENGER RNA; NICOTINAMIDE METHYLTRANSFERASE; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; ALBUMINOID; N(1)-METHYLNICOTINAMIDE; NICOTINAMIDE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; INFLAMMATION; KIDNEY CELL; KIDNEY FIBROSIS; KIDNEY PROXIMAL TUBULE; LIPOTOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEINURIA; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALBUMINS; ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; FATTY ACIDS, NONESTERIFIED; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED C57BL; NIACINAMIDE; NICOTINAMIDE N-METHYLTRANSFERASE; OXIDATIVE STRESS; PROTEINURIA; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 84945176836     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.10.414     Document Type: Article

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