The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex i inhibitors

Biochemical Journal

Volumn 436, Issue 1, 2011, Pages 145-155

  Parsons, Richard B ^a   Aravindan, Shylesh ^b   Kadampeswaran, Anusha ^b   Evans, Emily A ^b   Sandhu, Kanwaljeet K ^b   Levy, Elizabeth R ^a   Thomas, Martin G ^a   Austen, Brian M ^b   Ramsden, David B ^c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST GEORGE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Cancer; Cytoprotection; Energy metabolism; N methylation; NADH dehydrogenase (ubiquinone) iron sulfur protein 3 (NDUFS3); Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1 METHYLNICOTINAMIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; NICOTINAMIDE METHYLTRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE;

ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

1-METHYL-4-PHENYLPYRIDINIUM; ADENOSINE TRIPHOSPHATE; CELL LINE, TUMOR; ELECTRON TRANSPORT COMPLEX I; HUMANS; NADH DEHYDROGENASE; NEUROBLASTOMA; NIACINAMIDE; NICOTINAMIDE N-METHYLTRANSFERASE;

EID: 79955526612     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101685     Document Type: Article

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