MicroRNA-145 regulates osteoblastic differentiation by targeting the transcription factor Cbfb

FEBS Letters

Volumn 589, Issue 21, 2015, Pages 3302-3308

  Fukuda, Toru ^a,c   Ochi, Hiroki ^a,c   Sunamura, Satoko ^a,c   Haiden, Akina ^b   Bando, Waka ^b   Inose, Hiroyuki ^a   Okawa, Atsushi ^a   Asou, Yoshinori ^a   Takeda, Shu ^a,c  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT   (Japan)

Author keywords

Core binding factor beta; MicroRNA; Osteoblast

Indexed keywords

ALKALINE PHOSPHATASE; CORE BINDING FACTOR BETA; MESSENGER RNA; MICRORNA; MICRORNA 145; MICRORNA 34C; TRANSCRIPTION FACTOR RUNX; UNCLASSIFIED DRUG; CBFB PROTEIN, HUMAN; CBFB PROTEIN, MOUSE; MIRN145 MICRORNA, HUMAN; MIRN145 MICRORNA, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; 3T3 CELL LINE; ANIMAL; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; MOUSE; PHYSIOLOGY; PROMOTER REGION;

3T3 CELLS; ANIMALS; BONE REGENERATION; CELL DIFFERENTIATION; CELL LINE; CORE BINDING FACTOR BETA SUBUNIT; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MICE; MICRORNAS; OSTEOBLASTS; PROMOTER REGIONS, GENETIC;

EID: 84945143756     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.09.024     Document Type: Article

References (44)

1. G. Karsenty, H.M. Kronenberg, and C. Settembre Genetic control of bone formation Annu. Rev. Cell Dev. Biol. 25 2009 629 648
2. T. Komori Regulation of osteoblast differentiation by transcription factors J. Cell. Biochem. 99 2006 1233 1239
3. A. Augello, and C. De Bari The regulation of differentiation in mesenchymal stem cells Hum. Gene Ther. 21 2010 1226 1238
4. D.J. Kelly, and C.R. Jacobs The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells Birth Defects Res. C, Embryo Today 90 2010 75 85
5. M.N. Knight, and K.D. Hankenson Mesenchymal stem cells in bone regeneration Adv. Wound Care 2 2013 306 316
6. M.K. Bergenstock, and N.C. Partridge Parathyroid hormone stimulation of noncanonical Wnt signaling in bone Ann. N. Y. Acad. Sci. 1116 2007 354 359
7. E. Canalis, V. Deregowski, R.C. Pereira, and E. Gazzerro Signals that determine the fate of osteoblastic cells J. Endocrinol. Invest. 28 2005 3 7
8. P.J. Marie Fibroblast growth factor signaling controlling osteoblast differentiation Gene 316 2003 23 32
9. P. Ducy, R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 1997 747 754
10. T. Komori, and et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts Cell 89 1997 755 764
11. C.A. Yoshida, and T. Komori Role of Runx proteins in chondrogenesis Crit. Rev. Eukaryot. Gene Expr. 15 2005 243 254
12. T. Komori Regulation of skeletal development by the Runx family of transcription factors J. Cell. Biochem. 95 2005 445 453
13. E. Ogawa, M. Inuzuka, M. Maruyama, M. Satake, M. Naito-Fujimoto, Y. Ito, and K. Shigesada Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha Virology 194 1993 314 331
14. N. Kanatani, and et al. Cbf beta regulates Runx2 function isoform-dependently in postnatal bone development Dev. Biol. 296 2006 48 61
15. C.A. Yoshida, and et al. Core-binding factor beta interacts with Runx2 and is required for skeletal development Nat. Genet. 32 2002 633 638
16. M. Kundu, and et al. Cbfbeta interacts with Runx2 and has a critical role in bone development Nat. Genet. 32 2002 639 644
17. J. Miller, A. Horner, T. Stacy, C. Lowrey, J.B. Lian, G. Stein, G.H. Nuckolls, and N.A. Speck The core-binding factor beta subunit is required for bone formation and hematopoietic maturation Nat. Genet. 32 2002 645 649
18. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
19. O. Hobert Gene regulation by transcription factors and microRNAs Science 319 2008 1785 1786
20. W.P. Kloosterman, and R.H. Plasterk The diverse functions of microRNAs in animal development and disease Dev. Cell 11 2006 441 450
21. G. Stefani, and F.J. Slack Small non-coding RNAs in animal development Nat. Rev. Mol. Cell Biol. 9 2008 219 230
22. H. Inose, and et al. A microRNA regulatory mechanism of osteoblast differentiation Proc. Natl. Acad. Sci. U.S.A. 106 2009 20794 20799
23. M.Q. Hassan, and et al. MiR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells J. Biol. Chem. 287 2012 42084 42092
24. K. Kapinas, C. Kessler, T. Ricks, G. Gronowicz, and A.M. Delany MiR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop J. Biol. Chem. 285 2010 25221 25231
25. K. Kapinas, C.B. Kessler, and A.M. Delany MiR-29 suppression of osteonectin in osteoblasts: regulation during differentiation and by canonical Wnt signaling J. Cell. Biochem. 108 2009 216 224
26. E. Luzi, F. Marini, S.C. Sala, I. Tognarini, G. Galli, and M.L. Brandi Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor J. Bone Miner. Res. 23 2008 287 295
27. Y. Zeng, and et al. MicroRNA-100 regulates osteogenic differentiation of human adipose-derived mesenchymal stem cells by targeting BMPR2 FEBS Lett. 586 2012 2375 2381
28. J. Huang, L. Zhao, L. Xing, and D. Chen MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation Stem Cells 28 2010 357 364
29. Z. Li, M.Q. Hassan, S. Volinia, A.J. van Wijnen, J.L. Stein, C.M. Croce, J.B. Lian, and G.S. Stein A microRNA signature for a BMP2-induced osteoblast lineage commitment program Proc. Natl. Acad. Sci. U.S.A. 105 2008 13906 13911
30. Y. Zhang, R.L. Xie, C.M. Croce, J.L. Stein, J.B. Lian, A.J. van Wijnen, and G.S. Stein A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2 Proc. Natl. Acad. Sci. U.S.A. 108 2011 9863 9868
31. Y. Zhang, R.L. Xie, J. Gordon, K. LeBlanc, J.L. Stein, J.B. Lian, A.J. van Wijnen, and G.S. Stein Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2 J. Biol. Chem. 287 2012 21926 21935
32. T. Fukuda, and et al. Sema3A regulates bone-mass accrual through sensory innervations Nature 497 2013 490 493
33. K. Fujita, and et al. Vitamin E decreases bone mass by stimulating osteoclast fusion Nat. Med. 18 2012 589 594
34. N. Okuda, S. Takeda, K. Shinomiya, T. Muneta, S. Itoh, M. Noda, and Y. Asou ED-71, a novel vitamin D analog, promotes bone formation and angiogenesis and inhibits bone resorption after bone marrow ablation Bone 40 2007 281 292
35. Y. Nagata, and et al. Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a Arthritis Rheum. 60 2009 2677 2683
36. K.E. Lim, and et al. Core binding factor beta of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice J. Bone Miner. Res. 30 2015 715 722
37. K. Thirunavukkarasu, M. Mahajan, K.W. McLarren, S. Stifani, and G. Karsenty Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta Mol. Cell. Biol. 18 1998 4197 4208
38. J. Jia, Q. Tian, S. Ling, Y. Liu, S. Yang, and Z. Shao MiR-145 suppresses osteogenic differentiation by targeting Sp7 FEBS Lett. 587 2013 3027 3031
39. K. Nakashima, X. Zhou, G. Kunkel, Z. Zhang, J.M. Deng, R.R. Behringer, and B. de Crombrugghe The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation Cell 108 2002 17 29
40. K. Sasaki, and et al. Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta Proc. Natl. Acad. Sci. U.S.A. 93 1996 12359 12363
41. Q. Wang, and et al. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo Cell 87 1996 697 708
42. J. Wei, and et al. MiR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2 J. Cell Biol. 197 2012 509 521
43. N. Xu, T. Papagiannakopoulos, G. Pan, J.A. Thomson, and K.S. Kosik MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells Cell 137 2009 647 658
44. X. Wei, and C.Y. Shen Transcriptional regulation of oct4 in human bone marrow mesenchymal stem cells Stem Cells Dev. 20 2011 441 449