메뉴 건너뛰기




Volumn 18, Issue 7, 1998, Pages 4197-4208

Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfβ

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 0031836965     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.18.7.4197     Document Type: Article
Times cited : (231)

References (49)
  • 1
    • 0030802129 scopus 로고    scopus 로고
    • Groucho-dependent and -independent repression activities of Runt domain proteins
    • Aronson, B. D., A. L. Fisher, K. Blechman, M. Caudy, and J. P. Gergen. 1997. Groucho-dependent and -independent repression activities of Runt domain proteins. Mol. Cell. Biol. 17:5581-5587.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5581-5587
    • Aronson, B.D.1    Fisher, A.L.2    Blechman, K.3    Caudy, M.4    Gergen, J.P.5
  • 5
    • 0029016934 scopus 로고
    • Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain
    • Bae, S. C., E. Takahasi, Y. W. Zhang, E. Ogawa, K. Shigesada, Y. Namba, M. Satake, and Y. Ito. 1995. Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain. Gene 159:245-248.
    • (1995) Gene , vol.159 , pp. 245-248
    • Bae, S.C.1    Takahasi, E.2    Zhang, Y.W.3    Ogawa, E.4    Shigesada, K.5    Namba, Y.6    Satake, M.7    Ito, Y.8
  • 6
    • 20644434934 scopus 로고    scopus 로고
    • SpRunt-1, a new member of the runt domain family of transcription factors, is a positive regulator of the aboral ectoderm-specific CyIIIa gene in sea urchin embryos
    • Coffman, J. A., C. V. Kirchhamer, M. G. Harrington, and E. H. Davidson. 1996. SpRunt-1, a new member of the runt domain family of transcription factors, is a positive regulator of the aboral ectoderm-specific CyIIIA gene in sea urchin embryos. Dev. Biol. 174:43-54.
    • (1996) Dev. Biol. , vol.174 , pp. 43-54
    • Coffman, J.A.1    Kirchhamer, C.V.2    Harrington, M.G.3    Davidson, E.H.4
  • 7
    • 0029999211 scopus 로고    scopus 로고
    • Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1
    • Daga, A., C. A. Karlovich, K. Dumstrei, and U. Banerjee. 1996. Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1. Genes Dev. 10:1194-1205.
    • (1996) Genes Dev. , vol.10 , pp. 1194-1205
    • Daga, A.1    Karlovich, C.A.2    Dumstrei, K.3    Banerjee, U.4
  • 8
    • 0025949412 scopus 로고
    • Nuclear targeting sequences - A consensus
    • Dingwall, C., and R. A. Laskey. 1991. Nuclear targeting sequences - a consensus. Trends Biochem. Sci. 16:478-481.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 478-481
    • Dingwall, C.1    Laskey, R.A.2
  • 9
    • 0028927556 scopus 로고
    • Two distinct osteoblast-specific cis-acting elements control expression of the mouse osteocalcin gene
    • Ducy, P., and G. Karsenty. 1995. Two distinct osteoblast-specific cis-acting elements control expression of the mouse osteocalcin gene. Mol. Cell. Biol. 15:1858-1869.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1858-1869
    • Ducy, P.1    Karsenty, G.2
  • 10
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/ Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy, P., R. Zhang, V. Geoffroy, A. L. Ridall, and G. Karsenty. 1997. Osf2/ Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89:747-754.
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 11
    • 0031921591 scopus 로고    scopus 로고
    • Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function
    • Geoffroy, V., D. A. Corral, L. Zhou, B. Lee, and G. Karsenty. 1998. Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function. Mamm. Genome 9:54-57.
    • (1998) Mamm. Genome , vol.9 , pp. 54-57
    • Geoffroy, V.1    Corral, D.A.2    Zhou, L.3    Lee, B.4    Karsenty, G.5
  • 12
  • 13
    • 0030042980 scopus 로고    scopus 로고
    • Drosophila homologs of the proto-oncogene product PEBP2/CBFβ regulate the DNA-binding properties of Runt
    • Golling, G., L.-H. Li, M. Pepling, M. Stebbins, and J. P. Gergen. 1996. Drosophila homologs of the proto-oncogene product PEBP2/CBFβ regulate the DNA-binding properties of Runt. Mol. Cell. Biol. 16:932-942.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 932-942
    • Golling, G.1    Li, L.-H.2    Pepling, M.3    Stebbins, M.4    Gergen, J.P.5
  • 14
    • 0027256440 scopus 로고
    • Transcriptional repression by the Drosophila even-skipped protein: Definition of a minimal repression domain
    • Han, K., and J. L. Manley. 1993. Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. Genes Dev. 7:491-503.
    • (1993) Genes Dev. , vol.7 , pp. 491-503
    • Han, K.1    Manley, J.L.2
  • 15
    • 0027169185 scopus 로고
    • Functional domains of the Drosophila Engrailed protein
    • Han, K., and J. L. Manley. 1993. Functional domains of the Drosophila Engrailed protein. EMBO J. 12:2723-2733.
    • (1993) EMBO J. , vol.12 , pp. 2723-2733
    • Han, K.1    Manley, J.L.2
  • 16
    • 0000335533 scopus 로고    scopus 로고
    • The runt domain transcription factor, PEBP2/ CBF, and its involvement in human leukemia
    • M. Yaniv and J. Ghysdael (ed.), Birkhauser Verlag, Basel, Switzerland
    • Ito, Y., and S. C. Bae. 1997. The runt domain transcription factor, PEBP2/ CBF, and its involvement in human leukemia, p. 108-132. In M. Yaniv and J. Ghysdael (ed.), Cell cycle regulators and chromosomal translocation. Birkhauser Verlag, Basel, Switzerland.
    • (1997) Cell Cycle Regulators and Chromosomal Translocation , pp. 108-132
    • Ito, Y.1    Bae, S.C.2
  • 19
    • 12644307234 scopus 로고    scopus 로고
    • Functional dissection of the a and β subunits of transcription factor PEBP2α and the redox susceptibility of its DNA-binding activity
    • Kagoshima, H., Y. Akamatsu, Y. Ito, and K. Shigesada. 1996. Functional dissection of the a and β subunits of transcription factor PEBP2α and the redox susceptibility of its DNA-binding activity. J. Biol. Chem. 271:33074-33082.
    • (1996) J. Biol. Chem. , vol.271 , pp. 33074-33082
    • Kagoshima, H.1    Akamatsu, Y.2    Ito, Y.3    Shigesada, K.4
  • 20
    • 0025047508 scopus 로고
    • The Drosophila segmentation gene runt encodes a novel regulatory protein that is also expressed in the developing nervous system
    • Kania, M. A., A. S. Bonner, J. B. Duffy, and J. P. Gergen. 1990. The Drosophila segmentation gene runt encodes a novel regulatory protein that is also expressed in the developing nervous system. Genes Dev. 4:1701-1713.
    • (1990) Genes Dev. , vol.4 , pp. 1701-1713
    • Kania, M.A.1    Bonner, A.S.2    Duffy, J.B.3    Gergen, J.P.4
  • 22
    • 0031940065 scopus 로고    scopus 로고
    • Intrinsic transcriptional activation-inhibition domains of the polymavirus enhancer binding protein 2/core binding factor a subunit revealed in the presence of the β subunit
    • Kanno, T., Y. Kanno, L.-F. Chen, E. Ogawa, W.-Y. Kim, and Y. Ito. 1998. Intrinsic transcriptional activation-inhibition domains of the polymavirus enhancer binding protein 2/core binding factor a subunit revealed in the presence of the β subunit. Mol. Cell. Biol. 18:2444-2454.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2444-2454
    • Kanno, T.1    Kanno, Y.2    Chen, L.-F.3    Ogawa, E.4    Kim, W.-Y.5    Ito, Y.6
  • 23
    • 0023665902 scopus 로고
    • An analysis of 5′-noncoding sequences of 699 vertebrate messenger RNAs
    • Kozak, M. 1987. An analysis of 5′-noncoding sequences of 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:8125-8148.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 24
    • 0030012618 scopus 로고    scopus 로고
    • A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA-hinding ability and the transforming activity on fibroblasts
    • Kurokawa, M., T. Tanaka, K. Tanaka, N. Hirano, S. Ogawa, K. Mitani, Y. Yazaki, and H. Hirai. 1996. A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA-hinding ability and the transforming activity on fibroblasts. J. Biol. Chem. 271:16870-16876.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16870-16876
    • Kurokawa, M.1    Tanaka, T.2    Tanaka, K.3    Hirano, N.4    Ogawa, S.5    Mitani, K.6    Yazaki, Y.7    Hirai, H.8
  • 25
    • 0030927622 scopus 로고    scopus 로고
    • Missense mutations abolishing DNA-binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia
    • Lee, B., K. Thirunavukkarasu, L. Zhou, L. Pastore, A. Baldini, J. Hecht, V. Geoffroy, P. Ducy, and G. Karsenty. 1997. Missense mutations abolishing DNA-binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nat. Genet. 16:307-310.
    • (1997) Nat. Genet. , vol.16 , pp. 307-310
    • Lee, B.1    Thirunavukkarasu, K.2    Zhou, L.3    Pastore, L.4    Baldini, A.5    Hecht, J.6    Geoffroy, V.7    Ducy, P.8    Karsenty, G.9
  • 26
    • 0028786125 scopus 로고
    • Functional domains of the t(8;21) fusion protein, AML-1/ETO
    • Lenny, N., S. Meyers, and S. W. Hiebert. 1995. Functional domains of the t(8;21) fusion protein, AML-1/ETO. Oncogene 11:1761-1769.
    • (1995) Oncogene , vol.11 , pp. 1761-1769
    • Lenny, N.1    Meyers, S.2    Hiebert, S.W.3
  • 27
    • 0028839054 scopus 로고
    • Subcellular localization of the α and β subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF
    • Lu, J., M. Maruyama, M. Satake, S.-C. Bae, E. Ogawa, H. Kagoshima, K. Shigesada, and Y. Ito. 1995. Subcellular localization of the α and β subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF. Mol. Cell. Biol. 15:1651-1661.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1651-1661
    • Lu, J.1    Maruyama, M.2    Satake, M.3    Bae, S.-C.4    Ogawa, E.5    Kagoshima, H.6    Shigesada, K.7    Ito, Y.8
  • 28
    • 0029868498 scopus 로고    scopus 로고
    • Functional domains of the transcription factor USF2: Atypical nuclear localization signals and context-dependent transcriptional activation domains
    • Luo, X., and Sawadogo, M. 1996. Functional domains of the transcription factor USF2: atypical nuclear localization signals and context-dependent transcriptional activation domains. Mol. Cell. Biol. 16:1367-1375.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1367-1375
    • Luo, X.1    Sawadogo, M.2
  • 29
    • 0027383818 scopus 로고
    • Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: The runt homology domain is required for DNA binding and protein-protein interactions
    • Meyers, S., J. R. Downing, and S. W. Hiebert. 1993. Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions. Mol. Cell. Biol. 13:6336-6345.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6336-6345
    • Meyers, S.1    Downing, J.R.2    Hiebert, S.W.3
  • 31
    • 0029871929 scopus 로고    scopus 로고
    • Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13
    • Muragaki, Y., S. Mundlos, J. Upton, and B. R. Olsen. 1996. Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13. Science 272:548-551.
    • (1996) Science , vol.272 , pp. 548-551
    • Muragaki, Y.1    Mundlos, S.2    Upton, J.3    Olsen, B.R.4
  • 32
    • 0030756645 scopus 로고    scopus 로고
    • Developmental restriction of Mash-2 expression in trophoblasts correlates with potential activation of the Notch-2 pathway
    • Nakayama, H., Y. Liu, S. Stifani, and J. C. Cross. 1997. Developmental restriction of Mash-2 expression in trophoblasts correlates with potential activation of the Notch-2 pathway. Dev. Genet. 21:21-30.
    • (1997) Dev. Genet. , vol.21 , pp. 21-30
    • Nakayama, H.1    Liu, Y.2    Stifani, S.3    Cross, J.C.4
  • 33
    • 0030964105 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: Signals, mechanisms and regulation
    • Nigg, E. A. 1997. Nucleocytoplasmic transport: signals, mechanisms and regulation. Nature 386:779-787.
    • (1997) Nature , vol.386 , pp. 779-787
    • Nigg, E.A.1
  • 34
    • 0027220003 scopus 로고
    • PEBP2/PEA2 represents a new family of transcription factors homologous to the products of the Drosophila runt and the human AML1 gene
    • Ogawa, E., M. Maruyama, H. Kagoshima, M. Inuzuka, J. Lu, M. Satake, K. Shigesada, and Y. Ito. 1993. PEBP2/PEA2 represents a new family of transcription factors homologous to the products of the Drosophila runt and the human AML1 gene. Proc. Natl. Acad. Sci. USA 90:6859-6863.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6859-6863
    • Ogawa, E.1    Maruyama, M.2    Kagoshima, H.3    Inuzuka, M.4    Lu, J.5    Satake, M.6    Shigesada, K.7    Ito, Y.8
  • 35
    • 0027184229 scopus 로고
    • Molecular cloning and characterization of PEBP2β, the heterodimeric partner of a novel Drosophila Runt-related DNA-binding protein. PEBP2α
    • Ogawa, E., M. Inuzuka, M. Maruyama, M. Satake, M. Naito-Fujimoto, Y. Ito, and K. Shigesada. 1993. Molecular cloning and characterization of PEBP2β, the heterodimeric partner of a novel Drosophila Runt-related DNA-binding protein. PEBP2α. Virology 194:314-331.
    • (1993) Virology , vol.194 , pp. 314-331
    • Ogawa, E.1    Inuzuka, M.2    Maruyama, M.3    Satake, M.4    Naito-Fujimoto, M.5    Ito, Y.6    Shigesada, K.7
  • 36
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda, T., J. van Deursen, S. W. Hiebert, G. Grosveld, and J. R. Downing. 1996. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84:321-330.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 38
    • 0030720332 scopus 로고    scopus 로고
    • The Groucho/transducin-like Enhancer of Split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3
    • Palaparti, A., A. Baratz, and S. Stifani. 1997. The Groucho/transducin-like Enhancer of Split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3. J. Biol. Chem. 272:26604-26610.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26604-26610
    • Palaparti, A.1    Baratz, A.2    Stifani, S.3
  • 39
    • 0344265606 scopus 로고
    • A vector for expressing GAL4 (1-147) fusion in mammalian cells
    • Sadowski, I., and M. Ptashne. 1989. A vector for expressing GAL4 (1-147) fusion in mammalian cells. Nucleic Acids Res. 17:7539.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7539
    • Sadowski, I.1    Ptashne, M.2
  • 41
    • 0029417005 scopus 로고
    • IIs directing synergistic activation of transcription
    • IIs directing synergistic activation of transcription. Science 270:1783-1788.
    • (1995) Science , vol.270 , pp. 1783-1788
    • Sauer, F.1    Hansen, S.K.2    Tjian, R.3
  • 42
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with "mini-extracts" prepared from small number of cells
    • Schreiber, E., P. Matthias, M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with "mini-extracts" prepared from small number of cells. Nucleic Acids Res. 17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.3    Schaffner, W.4
  • 43
    • 0017895980 scopus 로고
    • Gamma-ray-induced dominant mutations that cause skeletal abnormalities in mice. II. Description of proved mutations
    • Selby, P. B., and P. R. Selby. 1978. Gamma-ray-induced dominant mutations that cause skeletal abnormalities in mice. II. Description of proved mutations. Mutat. Res. 51:199-236.
    • (1978) Mutat. Res. , vol.51 , pp. 199-236
    • Selby, P.B.1    Selby, P.R.2
  • 44
    • 0023181094 scopus 로고
    • Animal model: Skeletal anomalies in mice with cleidocranial dysplasia
    • Sillence, D. O., H. E. Ritchie, and P. B. Selby. 1987. Animal model: skeletal anomalies in mice with cleidocranial dysplasia. Am. J. Med. Genet. 27:75-85.
    • (1987) Am. J. Med. Genet. , vol.27 , pp. 75-85
    • Sillence, D.O.1    Ritchie, H.E.2    Selby, P.B.3
  • 45
    • 0029583960 scopus 로고
    • A new transcription factor family associated with human leukemias
    • Speck, N. A., and T. Stacy. 1995. A new transcription factor family associated with human leukemias. Crit. Rev. Eukaryot. Gene Expr. 5:337-364.
    • (1995) Crit. Rev. Eukaryot. Gene Expr. , vol.5 , pp. 337-364
    • Speck, N.A.1    Stacy, T.2
  • 46
    • 0026936126 scopus 로고
    • Human homologs of a Drosophila Enhancer of Split gene product define a novel family of nuclear proteins
    • Stifani, S., C. M. Blaumueller, N. J. Redhead, R. E. Hill, and S. Artavanis-Tsakonas. 1992. Human homologs of a Drosophila Enhancer of Split gene product define a novel family of nuclear proteins. Nat. Genet. 2:119-126.
    • (1992) Nat. Genet. , vol.2 , pp. 119-126
    • Stifani, S.1    Blaumueller, C.M.2    Redhead, N.J.3    Hill, R.E.4    Artavanis-Tsakonas, S.5
  • 47
    • 0026603594 scopus 로고
    • Single-step purification of bacterially expressed polypeptides containing an oligo-histidine domain
    • Van Dyke, M. W., M. Sirito, and M. Sawadogo. 1992. Single-step purification of bacterially expressed polypeptides containing an oligo-histidine domain. Gene 111:99-104.
    • (1992) Gene , vol.111 , pp. 99-104
    • Van Dyke, M.W.1    Sirito, M.2    Sawadogo, M.3
  • 48
    • 0029918597 scopus 로고    scopus 로고
    • Disruption of the cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
    • Wang, Q., T. Stacy, M. Binder, M. Marin-Padilla, A. H. Sharpe, and N. A. Speck. 1996. Disruption of the cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc. Natl. Acad. Sci. USA 93:3444-3449.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3444-3449
    • Wang, Q.1    Stacy, T.2    Binder, M.3    Marin-Padilla, M.4    Sharpe, A.H.5    Speck, N.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.