MicroRNA-100 regulates osteogenic differentiation of human adipose-derived mesenchymal stem cells by targeting BMPR2

FEBS Letters

Volumn 586, Issue 16, 2012, Pages 2375-2381

  Zeng, Yang ^a   Qu, Xuebin ^a   Li, Hongling ^a   Huang, Shan ^a   Wang, Shihua ^a   Xu, Qilin ^a   Lin, Ruizhu ^a   Han, Qin ^a   Li, Jing ^a   Zhao, Robert Chunhua ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

BMPR2; hASCs; miR 100; Osteogenesis

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 2; LUCIFERASE; MICRORNA 100;

ADIPOSE DERIVED STEM CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN ADIPOSE DERIVED MESENCHYMAL STEM CELL; HUMAN CELL; IN VITRO STUDY; MICROARRAY ANALYSIS; OSTEOGENIC DIFFERENTIATION; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA INTERFERENCE;

ADIPOSE TISSUE; AMINO ACID SEQUENCE; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELL DIFFERENTIATION; DOWN-REGULATION; GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STEM CELLS; MICRORNAS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; OSTEOBLASTS; OSTEOGENESIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84864286762     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.05.049     Document Type: Article

References (23)

1. M. Locke, V. Feisst, and P.R. Dunbar Concise review: human adipose-derived stem cells: separating promise from clinical need Stem Cells 29 2011 404 411
2. S. Wang, X. Qu, and R.C. Zhao Mesenchymal stem cells hold promise for regenerative medicine Front. Med. 5 2011 372 378
3. J.M. Gimble, and F. Guilak Differentiation potential of adipose derived adult stem (ADAS) cells Curr. Top. Dev. Biol. 58 2003 137 160 (Pubitemid 137639499)
4. M. Thomas, J. Lieberman, and A. Lal Desperately seeking microRNA targets Nat. Struct. Mol. Biol. 17 2010 1169 1174
5. M. Esteller Non-coding RNAs in human disease Nat. Rev. Genet. 12 2011 861 874
6. E. Luzi, F. Marini, S.C. Sala, I. Tognarini, G. Galli, and M.L. Brandi Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor J. Bone Miner. Res. 23 2008 287 295 (Pubitemid 351160043)
7. E. Luzi, F. Marini, I. Tognarini, G. Galli, A. Falchetti, and M.L. Brandi The regulatory network Menin-MicroRNA 26a as a possible target for RNA-based therapy of bone diseases Nucleic Acid Ther. 2012 [Epub ahead of print]
8. Y.J. Kim, S.W. Bae, S.S. Yu, Y.C. Bae, and J.S. Jung miR-196a regulates proliferation and osteogenic differentiation in mesenchymal stem cells derived from human adipose tissue J. Bone Miner. Res. 24 2009 816 825
9. H.H. Cho, K.K. Shin, Y.J. Kim, J.S. Song, J.M. Kim, Y.C. Bae, C.D. Kim, and J.S. Jung NF-kappaB activation stimulates osteogenic differentiation of mesenchymal stem cells derived from human adipose tissue by increasing TAZ expression J. Cell. Physiol. 223 2010 168 177
10. S. Huang, S. Wang, C. Bian, Z. Yang, H. Zhou, Y. Zeng, H. Li, Q. Han, and R.C. Zhao Upregulation of miR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression Stem Cells Dev. 2012 [Epub ahead of print]
11. R. Hu, H. Li, W. Liu, L. Yang, Y.F. Tan, and X.H. Luo Targeting miRNAs in osteoblast differentiation and bone formation Expert Opin. Ther. Targets 14 2010 1109 1120
12. Z. Yang, C. Bian, H. Zhou, S. Huang, S. Wang, L. Liao, and R.C. Zhao MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1 Stem Cells Dev. 20 2011 259 267
13. Y. Cao, Z. Sun, L. Liao, Y. Meng, Q. Han, and R.C. Zhao Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo Biochem. Biophys. Res. Commun. 332 2005 370 379 (Pubitemid 40724988)
14. J. Massagué, and D. Wotton Transcriptional control by the TGFbeta/Smad signaling system EMBO J. 19 2000 1745 1754 (Pubitemid 30204386)
15. E. Balint, D. Lapointe, H. Drissi, C. van der Meijden, D.W. Young, A.J. van Wijnen, J.L. Stein, G.S. Stein, and J.B. Lian Phenotype discovery by gene expression profiling, mapping of biological processes linked to BMP-2-mediated osteoblast differentiation J. Cell. Biochem. 89 2003 401 426 (Pubitemid 36547274)
16. Anxun Wang, Xueqiang Ding, Shihu Sheng, and Zhaoyou Yao Bone morphogenetic protein receptor in the osteogenic differentiation of rat bone marrow stromal cells Yonsei Med. J. 51 2010 740 745
17. R.J. O'Keefe, and J. Mao Bone tissue engineering and regeneration, from discovery to the clinic - an overview Tissue Eng. Part B Rev. 17 2011 389 392
18. B. Feng, R. Wang, and L.B. Chen MiR-100 resensitizes docetaxel-resistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1 Cancer Lett. 317 2012 184 191
19. Y.S. Zheng, H. Zhang, X.J. Zhang, D.D. Feng, X.Q. Luo, C.W. Zeng, K.Y. Lin, H. Zhou, L.H. Qu, P. Zhang, and Y.Q. Chen MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia Oncogene 31 2012 80 92
20. S. Lobert, B. Jefferson, and K. Morris Regulation of β-tubulin isotypes by micro-RNA 100 in MCF7 breast cancer cells Cytoskeleton 68 2011 355 362
21. Q. Kang, W.X. Song, Q. Luo, N. Tang, J. Luo, and X. Luo A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells Stem Cells Dev. 18 2008 545 559
22. Qun Wang, Chunlan Huang, Ming Xue, and Xinping Zhang Expression of endogenous BMP-2 in periosteal progenitor cells is essential for bone healing Bone 48 2011 524 532
23. A. Javed, J.S. Bae, F. Afzal, S. Gutierrez, J. Pratap, S.K. Zaidi, Y. Lou, A.J. van Wijnen, J.L. Stein, G.S. Stein, and J.B. Lian Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal J. Biol. Chem. 83 2008 8412 8422