Critical role of c-jun N-terminal protein kinase in promoting mitochondrial dysfunction and acute liver injury

Redox Biology

Volumn 6, Issue , 2015, Pages 552-564

  Jang, Sehwan ^a   Yu, Li Rong ^b   Abdelmegeed, Mohamed A ^a   Gao, Yuan ^b   Banerjee, Atrayee ^a   Song, Byoung Joon ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Acute liver injury; Carbon tetrachloride; Differential proteomics; JNK; Mitochondria; Protein phosphorylation

Indexed keywords

ALANINE AMINOTRANSFERASE; ALDEHYDE DEHYDROGENASE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIOXIDANT; BI 78D3; CARBON TETRACHLORIDE; CYTOCHROME P450 2E1; MITOCHONDRIAL PROTEIN; OXOGLUTARATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; SU 3327; UNCLASSIFIED DRUG; [2 (2,2,6,6 TETRAMETHYLPIPERIDINE 1 OXYL 4 YLAMINO) 2 OXOETHYL]TRIPPHENYLPHOSPHENIUM CHLORIDE; BAX PROTEIN, MOUSE; PROTEIN BAX;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOPRECIPITATION; LIVER HISTOLOGY; LIVER INJURY; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; MASS SPECTROMETRY; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEOMICS; SINGLE DRUG DOSE; 129 MOUSE; ACUTE LUNG INJURY; ANIMAL; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; TRANSGENIC MOUSE;

ACUTE LUNG INJURY; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE, 129 STRAIN; MICE, TRANSGENIC; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84944740153     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2015.09.040     Document Type: Article

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