SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury

Experimental and Molecular Medicine

Volumn 38, Issue 4, 2006, Pages 408-416

  Lee, Kyung Hoon ^a,b   Kim, Sang Eun ^a   Lee, Yun Song ^a  

^a Sungkyunkwan University   (South Korea)

^b Samsung Medical Center   (South Korea)

Author keywords

Anthra(1,9 cd)pyrazol 6(2H) one; Ischemia; JNK mitogen activated protein kinases; Liver; Reperfusion injury

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CHEMOKINE; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; ALANINE AMINOTRANSFERASE; GELATIN; MALONALDEHYDE; MYELOPEROXIDASE; RIBONUCLEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DESTRUCTION; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; HISTOPATHOLOGY; INFLAMMATORY INFILTRATE; LEUKOCYTE; LIVER INJURY; LIVER ISCHEMIA; LIVER PARENCHYMA; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANALYSIS OF VARIANCE; DISEASE EXACERBATION; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOBLOTTING; LIVER CELL DAMAGE; MALE; MOUSE STRAIN; OXIDATIVE STRESS; RIBONUCLEASE PROTECTION ASSAY; TISSUE LEVEL; ZYMOGRAPHY;

EID: 33748707782     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2006.48     Document Type: Article

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