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Volumn 37, Issue 3, 2016, Pages 3683-3695

An integrative transcriptomic analysis reveals p53 regulated miRNA, mRNA, and lncRNA networks in nasopharyngeal carcinoma

Author keywords

Gene regulating network; Long noncoding RNAs (lncRNAs); microRNAs (miRNAs); mRNAs; Nasopharyngeal carcinoma (NPC); p53

Indexed keywords

LONG UNTRANSLATED RNA; MESSENGER RNA; MICRORNA; PROTEIN P53;

EID: 84944712185     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-4156-x     Document Type: Article
Times cited : (61)

References (77)
  • 1
    • 80155151745 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: advances in genomics and molecular genetics
    • PID: 22038010
    • Zeng Z, Huang H, Zhang W, Xiang B, Zhou M, et al. Nasopharyngeal carcinoma: advances in genomics and molecular genetics. Sci China Life Sci. 2011;54:966–75.
    • (2011) Sci China Life Sci , vol.54 , pp. 966-975
    • Zeng, Z.1    Huang, H.2    Zhang, W.3    Xiang, B.4    Zhou, M.5
  • 2
    • 12144289414 scopus 로고    scopus 로고
    • A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BD2cXitFCgtLo%3D, PID: 15026332
    • Xiong W, Zeng ZY, Xia JH, Xia K, Shen SR, et al. A susceptibility locus at chromosome 3p21 linked to familial nasopharyngeal carcinoma. Cancer Res. 2004;64:1972–4.
    • (2004) Cancer Res , vol.64 , pp. 1972-1974
    • Xiong, W.1    Zeng, Z.Y.2    Xia, J.H.3    Xia, K.4    Shen, S.R.5
  • 3
    • 33645800172 scopus 로고    scopus 로고
    • Family-based association analysis validates chromosome 3p21 as a putative nasopharyngeal carcinoma susceptibility locus
    • COI: 1:CAS:528:DC%2BD28XitlelsLY%3D, PID: 16540749
    • Zeng Z, Zhou Y, Zhang W, Li X, Xiong W, et al. Family-based association analysis validates chromosome 3p21 as a putative nasopharyngeal carcinoma susceptibility locus. Genet Med. 2006;8:156–60.
    • (2006) Genet Med , vol.8 , pp. 156-160
    • Zeng, Z.1    Zhou, Y.2    Zhang, W.3    Li, X.4    Xiong, W.5
  • 5
    • 84899456801 scopus 로고    scopus 로고
    • LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation
    • COI: 1:CAS:528:DC%2BC3sXot1CksLg%3D, PID: 23708661
    • Liao Q, Zeng Z, Guo X, Li X, Wei F, et al. LPLUNC1 suppresses IL-6-induced nasopharyngeal carcinoma cell proliferation via inhibiting the Stat3 activation. Oncogene. 2014;33:2098–109.
    • (2014) Oncogene , vol.33 , pp. 2098-2109
    • Liao, Q.1    Zeng, Z.2    Guo, X.3    Li, X.4    Wei, F.5
  • 6
    • 84877024987 scopus 로고    scopus 로고
    • LPLUNC1 inhibits nasopharyngeal carcinoma cell growth via down-regulation of the MAP kinase and cyclin D1/E2F pathways
    • COI: 1:CAS:528:DC%2BC3sXnsFWqs74%3D, PID: 23650533
    • Yang Y, Liao Q, Wei F, Li X, Zhang W, et al. LPLUNC1 inhibits nasopharyngeal carcinoma cell growth via down-regulation of the MAP kinase and cyclin D1/E2F pathways. PLoS One. 2013;8, e62869.
    • (2013) PLoS One , vol.8
    • Yang, Y.1    Liao, Q.2    Wei, F.3    Li, X.4    Zhang, W.5
  • 7
    • 33845636596 scopus 로고    scopus 로고
    • Analysis of gene expression identifies candidate molecular markers in nasopharyngeal carcinoma using microdissection and cDNA microarray
    • COI: 1:CAS:528:DC%2BD28Xht12gs7nO, PID: 16941191
    • Zeng Z, Zhou Y, Xiong W, Luo X, Zhang W, et al. Analysis of gene expression identifies candidate molecular markers in nasopharyngeal carcinoma using microdissection and cDNA microarray. J Cancer Res Clin Oncol. 2007;133:71–81.
    • (2007) J Cancer Res Clin Oncol , vol.133 , pp. 71-81
    • Zeng, Z.1    Zhou, Y.2    Xiong, W.3    Luo, X.4    Zhang, W.5
  • 8
    • 33845343269 scopus 로고    scopus 로고
    • Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathway
    • COI: 1:CAS:528:DC%2BD28XhtleisrbF, PID: 16996564
    • Zeng ZY, Zhou YH, Zhang WL, Xiong W, Fan SQ, et al. Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathway. Hum Pathol. 2007;38:120–33.
    • (2007) Hum Pathol , vol.38 , pp. 120-133
    • Zeng, Z.Y.1    Zhou, Y.H.2    Zhang, W.L.3    Xiong, W.4    Fan, S.Q.5
  • 9
    • 84925493245 scopus 로고    scopus 로고
    • Lactotransferrin could be a novel independent molecular prognosticator of nasopharyngeal carcinoma
    • PID: 25286756
    • Zhang W, Fan S, Zou G, Shi L, Zeng Z, et al. Lactotransferrin could be a novel independent molecular prognosticator of nasopharyngeal carcinoma. Tumour Biol. 2015;36:675–83.
    • (2015) Tumour Biol , vol.36 , pp. 675-683
    • Zhang, W.1    Fan, S.2    Zou, G.3    Shi, L.4    Zeng, Z.5
  • 10
    • 66449114612 scopus 로고    scopus 로고
    • Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis
    • COI: 1:CAS:528:DC%2BD1MXlsVCrt7o%3D
    • Zhang W, Zeng Z, Zhou Y, Xiong W, Fan S, et al. Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis. Acta Biochim Biophys Sin (Shanghai). 2009;41:414–28.
    • (2009) Acta Biochim Biophys Sin (Shanghai) , vol.41 , pp. 414-428
    • Zhang, W.1    Zeng, Z.2    Zhou, Y.3    Xiong, W.4    Fan, S.5
  • 11
    • 84865626282 scopus 로고    scopus 로고
    • Evaluation of the prognostic value of TGF-beta superfamily type I receptor and TGF-beta type II receptor expression in nasopharyngeal carcinoma using high-throughput tissue microarrays
    • COI: 1:CAS:528:DC%2BC38XhtFKisLvK, PID: 22391627
    • Zhang W, Zeng Z, Fan S, Wang J, Yang J, et al. Evaluation of the prognostic value of TGF-beta superfamily type I receptor and TGF-beta type II receptor expression in nasopharyngeal carcinoma using high-throughput tissue microarrays. J Mol Histol. 2012;43:297–306.
    • (2012) J Mol Histol , vol.43 , pp. 297-306
    • Zhang, W.1    Zeng, Z.2    Fan, S.3    Wang, J.4    Yang, J.5
  • 12
    • 84879740162 scopus 로고    scopus 로고
    • Innate immune protein lactotransferrin prevents initiation and arrests progression of nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BC2cXmsVejtLc%3D
    • Huang HB, Deng M, Zheng Y, Zhou YH, Zhang WL, et al. Innate immune protein lactotransferrin prevents initiation and arrests progression of nasopharyngeal carcinoma. Prog Biochem Biophys. 2013;40:319–24.
    • (2013) Prog Biochem Biophys , vol.40 , pp. 319-324
    • Huang, H.B.1    Deng, M.2    Zheng, Y.3    Zhou, Y.H.4    Zhang, W.L.5
  • 13
    • 84955647913 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded small RNA 1 (EBER-1) could predict good prognosis in nasopharyngeal carcinoma
    • Zeng Z, Fan S, Zhang X, Li S, Zhou M, et al. Epstein-Barr virus-encoded small RNA 1 (EBER-1) could predict good prognosis in nasopharyngeal carcinoma. Clin Transl Oncol. 2015;
    • (2015) Clin Transl Oncol
    • Zeng, Z.1    Fan, S.2    Zhang, X.3    Li, S.4    Zhou, M.5
  • 14
    • 58149165366 scopus 로고    scopus 로고
    • An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma
    • COI: 1:CAS:528:DC%2BD1cXhsVSmsrvE, PID: 18337559
    • Xiong W, Wu X, Starnes S, Johnson SK, Haessler J, et al. An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma. Blood. 2008;112:4235–46.
    • (2008) Blood , vol.112 , pp. 4235-4246
    • Xiong, W.1    Wu, X.2    Starnes, S.3    Johnson, S.K.4    Haessler, J.5
  • 15
    • 84871156667 scopus 로고    scopus 로고
    • Advances in microRNAs and TP53 gene regulatory network
    • COI: 1:CAS:528:DC%2BC3sXhsVeit7rF
    • Gong ZJ, Huang HB, Xu K, Liang F, Li XL, et al. Advances in microRNAs and TP53 gene regulatory network. Prog Biochem Biophys. 2012;39:1133–44.
    • (2012) Prog Biochem Biophys , vol.39 , pp. 1133-1144
    • Gong, Z.J.1    Huang, H.B.2    Xu, K.3    Liang, F.4    Li, X.L.5
  • 16
    • 84880857890 scopus 로고    scopus 로고
    • Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program
    • COI: 1:CAS:528:DC%2BC3sXpsFGrsLs%3D, PID: 23515929
    • Li Y, Gordon MW, Xu-Monette ZY, Visco C, Tzankov A, et al. Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013;121:4529–40.
    • (2013) Blood , vol.121 , pp. 4529-4540
    • Li, Y.1    Gordon, M.W.2    Xu-Monette, Z.Y.3    Visco, C.4    Tzankov, A.5
  • 17
    • 84913529378 scopus 로고    scopus 로고
    • LOC401317, a p53-regulated long non-coding RNA, inhibits cell proliferation and induces apoptosis in the nasopharyngeal carcinoma cell line HNE2
    • PID: 25422887
    • Gong Z, Zhang S, Zeng Z, Wu H, Yang Q, et al. LOC401317, a p53-regulated long non-coding RNA, inhibits cell proliferation and induces apoptosis in the nasopharyngeal carcinoma cell line HNE2. PLoS One. 2014;9, e110674.
    • (2014) PLoS One , vol.9
    • Gong, Z.1    Zhang, S.2    Zeng, Z.3    Wu, H.4    Yang, Q.5
  • 18
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • COI: 1:CAS:528:DC%2BC3cXhtVais7nN, PID: 20703300
    • Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010;466:835–40.
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 19
    • 77951964981 scopus 로고    scopus 로고
    • Posttranscriptional regulation of microRNA biogenesis in animals
    • COI: 1:CAS:528:DC%2BC3cXms1alsLk%3D, PID: 20471939
    • Siomi H, Siomi MC. Posttranscriptional regulation of microRNA biogenesis in animals. Mol Cell. 2010;38:323–32.
    • (2010) Mol Cell , vol.38 , pp. 323-332
    • Siomi, H.1    Siomi, M.C.2
  • 20
    • 73349108109 scopus 로고    scopus 로고
    • The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2
    • COI: 1:CAS:528:DC%2BD1MXhsV2gsLbO, PID: 19898466
    • Rybak A, Fuchs H, Hadian K, Smirnova L, Wulczyn EA, et al. The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2. Nat Cell Biol. 2009;11:1411–20.
    • (2009) Nat Cell Biol , vol.11 , pp. 1411-1420
    • Rybak, A.1    Fuchs, H.2    Hadian, K.3    Smirnova, L.4    Wulczyn, E.A.5
  • 21
    • 84905057933 scopus 로고    scopus 로고
    • Establishment of cardiomyocyte-specific miR-30b transgenic mice and exploring the function of miR-30b
    • COI: 1:CAS:528:DC%2BC2MXotFeqsLs%3D
    • Fan YY, Long B, Liu F, Zhou LY, Wang K, et al. Establishment of cardiomyocyte-specific miR-30b transgenic mice and exploring the function of miR-30b. Prog Biochem Biophys. 2014;41:575–82.
    • (2014) Prog Biochem Biophys , vol.41 , pp. 575-582
    • Fan, Y.Y.1    Long, B.2    Liu, F.3    Zhou, L.Y.4    Wang, K.5
  • 22
    • 84922359281 scopus 로고    scopus 로고
    • Dicer and its miRNAs are necessary gene and regulatory factors for differentiation and proliferation of vascular smooth muscle cell
    • COI: 1:CAS:528:DC%2BC2MXhsVCqtLnL
    • Pan YQ, Pan B, Liu XY, Li RZ, Yue JM. Dicer and its miRNAs are necessary gene and regulatory factors for differentiation and proliferation of vascular smooth muscle cell. Prog Biochem Biophys. 2014;41:1255–64.
    • (2014) Prog Biochem Biophys , vol.41 , pp. 1255-1264
    • Pan, Y.Q.1    Pan, B.2    Liu, X.Y.3    Li, R.Z.4    Yue, J.M.5
  • 23
    • 84903131625 scopus 로고    scopus 로고
    • The research progress of microRNAs in aging
    • COI: 1:CAS:528:DC%2BC2MXitFKmtL4%3D
    • Wu G, Wang D, Huang Y, Han JD. The research progress of microRNAs in aging. Prog Biochem Biophys. 2014;41:273–87.
    • (2014) Prog Biochem Biophys , vol.41 , pp. 273-287
    • Wu, G.1    Wang, D.2    Huang, Y.3    Han, J.D.4
  • 24
    • 84869067808 scopus 로고    scopus 로고
    • A systematic screen reveals microRNA clusters that significantly regulate four major signaling pathways
    • COI: 1:CAS:528:DC%2BC38XhslCqurfO, PID: 23144891
    • Becker LE, Lu Z, Chen W, Xiong W, Kong M, et al. A systematic screen reveals microRNA clusters that significantly regulate four major signaling pathways. PLoS One. 2012;7, e48474.
    • (2012) PLoS One , vol.7
    • Becker, L.E.1    Lu, Z.2    Chen, W.3    Xiong, W.4    Kong, M.5
  • 25
    • 79959918202 scopus 로고    scopus 로고
    • Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis
    • COI: 1:CAS:528:DC%2BC3MXot1eguro%3D, PID: 21646541
    • Ma X, Kumar M, Choudhury SN, Becker Buscaglia LE, Barker JR, et al. Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis. Proc Natl Acad Sci U S A. 2011;108:10144–9.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10144-10149
    • Ma, X.1    Kumar, M.2    Choudhury, S.N.3    Becker Buscaglia, L.E.4    Barker, J.R.5
  • 26
    • 84930204546 scopus 로고    scopus 로고
    • The oncogenic microRNA miR-21 promotes regulated necrosis in mice
    • PID: 25990308
    • Ma X, Conklin DJ, Li F, Dai Z, Hua X, et al. The oncogenic microRNA miR-21 promotes regulated necrosis in mice. Nat Commun. 2015;6:7151.
    • (2015) Nat Commun , vol.6 , pp. 7151
    • Ma, X.1    Conklin, D.J.2    Li, F.3    Dai, Z.4    Hua, X.5
  • 27
    • 84940177025 scopus 로고    scopus 로고
    • Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma
    • Bo H, Gong Z, Zhang W, Li X, Zeng Y, et al. Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma. Oncotarget. 2015;6(24):20404–18.
    • (2015) Oncotarget , vol.6 , Issue.24 , pp. 20404-20418
    • Bo, H.1    Gong, Z.2    Zhang, W.3    Li, X.4    Zeng, Y.5
  • 29
    • 84903146757 scopus 로고    scopus 로고
    • Cloning and functional characterization of a novel long non-coding RNA gene associated with hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2cXitFynu7bM
    • Tang K, Wei F, Bo H, Huang HB, Zhang WL, et al. Cloning and functional characterization of a novel long non-coding RNA gene associated with hepatocellular carcinoma. Prog Biochem Biophys. 2014;41:153–62.
    • (2014) Prog Biochem Biophys , vol.41 , pp. 153-162
    • Tang, K.1    Wei, F.2    Bo, H.3    Huang, H.B.4    Zhang, W.L.5
  • 30
    • 84899043504 scopus 로고    scopus 로고
    • Expression of LINC00312, a long intergenic non-coding RNA, is negatively correlated with tumor size but positively correlated with lymph node metastasis in nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BC3sXhsFOhur3O, PID: 23529758
    • Zhang W, Huang C, Gong Z, Zhao Y, Tang K, et al. Expression of LINC00312, a long intergenic non-coding RNA, is negatively correlated with tumor size but positively correlated with lymph node metastasis in nasopharyngeal carcinoma. J Mol Histol. 2013;44:545–54.
    • (2013) J Mol Histol , vol.44 , pp. 545-554
    • Zhang, W.1    Huang, C.2    Gong, Z.3    Zhao, Y.4    Tang, K.5
  • 31
    • 84927637298 scopus 로고    scopus 로고
    • Progress of long noncoding RNA HOTAIR in human cancer
    • COI: 1:CAS:528:DC%2BC2MXitVCkur%2FF
    • Li YW, Wang YM, Zhang XY, Xue D, Kuang B, et al. Progress of long noncoding RNA HOTAIR in human cancer. Prog Biochem Biophys. 2015;42:228–35.
    • (2015) Prog Biochem Biophys , vol.42 , pp. 228-235
    • Li, Y.W.1    Wang, Y.M.2    Zhang, X.Y.3    Xue, D.4    Kuang, B.5
  • 32
    • 84938739201 scopus 로고    scopus 로고
    • Evolutionary annotation of conserved long non-coding RNAs in major mammalian species, Sci China Life Sci
    • Bu D, Luo H, Jiao F, Fang S, Tan C, et al. Evolutionary annotation of conserved long non-coding RNAs in major mammalian species. Sci China Life Sci. 2015;
    • (2015) et al
    • Bu, D.1    Luo, H.2    Jiao, F.3    Fang, S.4    Tan, C.5
  • 33
    • 84905650933 scopus 로고    scopus 로고
    • A bioinformatics method for predicting long noncoding RNAs associated with vascular disease
    • COI: 1:CAS:528:DC%2BC2cXhtlKmsbnE, PID: 25104459
    • Li J, Gao C, Wang Y, Ma W, Tu J, et al. A bioinformatics method for predicting long noncoding RNAs associated with vascular disease. Sci China Life Sci. 2014;57:852–7.
    • (2014) Sci China Life Sci , vol.57 , pp. 852-857
    • Li, J.1    Gao, C.2    Wang, Y.3    Ma, W.4    Tu, J.5
  • 34
    • 84906505613 scopus 로고    scopus 로고
    • Long noncoding RNA and epigenetic regulation
    • COI: 1:CAS:528:DC%2BC2MXhtVajtr%2FJ
    • Chen YN, Xiong XD. Long noncoding RNA and epigenetic regulation. Prog Biochem Biophys. 2014;41:723–30.
    • (2014) Prog Biochem Biophys , vol.41 , pp. 723-730
    • Chen, Y.N.1    Xiong, X.D.2
  • 35
    • 84919681009 scopus 로고    scopus 로고
    • Long noncoding RNA HOTAIR can serve as a common molecular marker for lymph node metastasis: a meta-analysis
    • COI: 1:CAS:528:DC%2BC2cXhtFyhsLbJ, PID: 25017366
    • Cai B, Wu Z, Liao K, Zhang S. Long noncoding RNA HOTAIR can serve as a common molecular marker for lymph node metastasis: a meta-analysis. Tumour Biol. 2014;35:8445–50.
    • (2014) Tumour Biol , vol.35 , pp. 8445-8450
    • Cai, B.1    Wu, Z.2    Liao, K.3    Zhang, S.4
  • 36
    • 84922393957 scopus 로고    scopus 로고
    • The lncRNA-MYC regulatory network in cancer
    • COI: 1:CAS:528:DC%2BC2cXhtl2nsrnF, PID: 25139102
    • Deng K, Guo X, Wang H, Xia J. The lncRNA-MYC regulatory network in cancer. Tumour Biol. 2014;35:9497–503.
    • (2014) Tumour Biol , vol.35 , pp. 9497-9503
    • Deng, K.1    Guo, X.2    Wang, H.3    Xia, J.4
  • 37
    • 84930900865 scopus 로고    scopus 로고
    • MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway
    • COI: 1:CAS:528:DC%2BC2cXitVSgtL%2FI, PID: 25431257
    • Dong Y, Liang G, Yuan B, Yang C, Gao R, et al. MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway. Tumour Biol. 2015;36:1477–86.
    • (2015) Tumour Biol , vol.36 , pp. 1477-1486
    • Dong, Y.1    Liang, G.2    Yuan, B.3    Yang, C.4    Gao, R.5
  • 38
    • 84925541437 scopus 로고    scopus 로고
    • Focusing on long noncoding RNA dysregulation in gastric cancer
    • COI: 1:CAS:528:DC%2BC2cXitFOrsr7N, PID: 25501508
    • Gan L, Xu M, Zhang Y, Zhang X, Guo W. Focusing on long noncoding RNA dysregulation in gastric cancer. Tumour Biol. 2015;36:129–41.
    • (2015) Tumour Biol , vol.36 , pp. 129-141
    • Gan, L.1    Xu, M.2    Zhang, Y.3    Zhang, X.4    Guo, W.5
  • 39
    • 84944275629 scopus 로고    scopus 로고
    • Invasion and metastasis-related long noncoding RNA expression profiles in hepatocellular carcinoma, Tumour Biol
    • Gao Y, Chen G, Zeng Y, Zeng J, Lin M, et al. Invasion and metastasis-related long noncoding RNA expression profiles in hepatocellular carcinoma. Tumour Biol. 2015;
    • (2015) et al
    • Gao, Y.1    Chen, G.2    Zeng, Y.3    Zeng, J.4    Lin, M.5
  • 40
    • 84920938274 scopus 로고    scopus 로고
    • Long non-coding RNAs: emerging players in gastric cancer
    • COI: 1:CAS:528:DC%2BC2cXhsV2ltbzM, PID: 25173641
    • Guo X, Xia J, Deng K. Long non-coding RNAs: emerging players in gastric cancer. Tumour Biol. 2014;35:10591–600.
    • (2014) Tumour Biol , vol.35 , pp. 10591-10600
    • Guo, X.1    Xia, J.2    Deng, K.3
  • 41
    • 84921937504 scopus 로고    scopus 로고
    • Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer
    • COI: 1:CAS:528:DC%2BC2cXhs1Cntb3P, PID: 25266799
    • Hajjari M, Khoshnevisan A, Shin YK. Molecular function and regulation of long non-coding RNAs: paradigms with potential roles in cancer. Tumour Biol. 2014;35:10645–63.
    • (2014) Tumour Biol , vol.35 , pp. 10645-10663
    • Hajjari, M.1    Khoshnevisan, A.2    Shin, Y.K.3
  • 42
    • 58049196616 scopus 로고    scopus 로고
    • MicroRNA in cancer prognosis
    • COI: 1:CAS:528:DC%2BD1cXhsFaqtr7F, PID: 19092157
    • Slack FJ, Weidhaas JB. MicroRNA in cancer prognosis. N Engl J Med. 2008;359:2720–2.
    • (2008) N Engl J Med , vol.359 , pp. 2720-2722
    • Slack, F.J.1    Weidhaas, J.B.2
  • 43
    • 84964435596 scopus 로고    scopus 로고
    • Epstein–Barr virus-encoded small RNA 1 (EBER-1) could predict 3 good prognosis in nasopharyngeal carcinoma
    • Zeng Z, Fan S, Zhang X, Li S, Zhou M, et al. Epstein–Barr virus-encoded small RNA 1 (EBER-1) could predict 3 good prognosis in nasopharyngeal carcinoma. Clin Transl Oncol. 2015;
    • (2015) Clin Transl Oncol
    • Zeng, Z.1    Fan, S.2    Zhang, X.3    Li, S.4    Zhou, M.5
  • 44
    • 84964203821 scopus 로고    scopus 로고
    • AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis
    • Zeng Z, Bo H, Gong Z, Lian Y, Li X, et al. AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis. Tumour Biol. 2015;
    • (2015) Tumour Biol
    • Zeng, Z.1    Bo, H.2    Gong, Z.3    Lian, Y.4    Li, X.5
  • 45
    • 84899513802 scopus 로고    scopus 로고
    • The effect and mechanism of PLUNC protein family against inflammation and carcinogenesis of nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BC2cXitV2js7%2FM
    • Wei F, Li XY, Li XL, Zhang WL, Liao QJ, et al. The effect and mechanism of PLUNC protein family against inflammation and carcinogenesis of nasopharyngeal carcinoma. Prog Biochem Biophys. 2014;41:24–31.
    • (2014) Prog Biochem Biophys , vol.41 , pp. 24-31
    • Wei, F.1    Li, X.Y.2    Li, X.L.3    Zhang, W.L.4    Liao, Q.J.5
  • 46
    • 84901718502 scopus 로고    scopus 로고
    • Noncoding RNAs: “our turn” to join the p53 network
    • PID: 24868101
    • Li Y, Lu H. Noncoding RNAs: “our turn” to join the p53 network. J Mol Cell Biol. 2014;6:179–80.
    • (2014) J Mol Cell Biol , vol.6 , pp. 179-180
    • Li, Y.1    Lu, H.2
  • 48
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • COI: 1:CAS:528:DC%2BC3cXht1KmsL%2FP, PID: 20935678
    • Kumar M, Lu Z, Takwi AA, Chen W, Callander NS, et al. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene. 2011;30:843–53.
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.3    Chen, W.4    Callander, N.S.5
  • 49
    • 84878987210 scopus 로고    scopus 로고
    • Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway
    • COI: 1:CAS:528:DC%2BC3sXptFCntr4%3D, PID: 23385064
    • Ma X, Choudhury SN, Hua X, Dai Z, Li Y. Interaction of the oncogenic miR-21 microRNA and the p53 tumor suppressor pathway. Carcinogenesis. 2013;34:1216–23.
    • (2013) Carcinogenesis , vol.34 , pp. 1216-1223
    • Ma, X.1    Choudhury, S.N.2    Hua, X.3    Dai, Z.4    Li, Y.5
  • 50
    • 68649113121 scopus 로고    scopus 로고
    • The p53 pathway encounters the microRNA world
    • COI: 1:CAS:528:DC%2BD1MXmslans7g%3D, PID: 19881912
    • Takwi A, Li Y. The p53 pathway encounters the microRNA world. Current genomics. 2009;10:194–7.
    • (2009) Current genomics , vol.10 , pp. 194-197
    • Takwi, A.1    Li, Y.2
  • 51
    • 47549109566 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
    • COI: 1:CAS:528:DC%2BD1cXosFGitrw%3D, PID: 18372920
    • Lu Z, Liu M, Stribinskis V, Klinge CM, Ramos KS, et al. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene. 2008;27:4373–9.
    • (2008) Oncogene , vol.27 , pp. 4373-4379
    • Lu, Z.1    Liu, M.2    Stribinskis, V.3    Klinge, C.M.4    Ramos, K.S.5
  • 52
    • 84901713192 scopus 로고    scopus 로고
    • The dichotomy of p53 regulation by noncoding RNAs
    • COI: 1:CAS:528:DC%2BC2cXptVCgtL4%3D, PID: 24706938
    • Deng Q, Becker L, Ma X, Zhong X, Young K, et al. The dichotomy of p53 regulation by noncoding RNAs. J Mol Cell Biol. 2014;6:198–205.
    • (2014) J Mol Cell Biol , vol.6 , pp. 198-205
    • Deng, Q.1    Becker, L.2    Ma, X.3    Zhong, X.4    Young, K.5
  • 53
    • 84862796512 scopus 로고    scopus 로고
    • An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BC38Xkslahtro%3D, PID: 22260379
    • Luo Z, Zhang L, Li Z, Li X, Li G, et al. An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma. BMC Med Genomics. 2012;5:3.
    • (2012) BMC Med Genomics , vol.5 , pp. 3
    • Luo, Z.1    Zhang, L.2    Li, Z.3    Li, X.4    Li, G.5
  • 54
    • 33748031414 scopus 로고    scopus 로고
    • Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BD28XotFWqt7w%3D, PID: 16912175
    • Sengupta S, den Boon JA, Chen IH, Newton MA, Dahl DB, et al. Genome-wide expression profiling reveals EBV-associated inhibition of MHC class I expression in nasopharyngeal carcinoma. Cancer Res. 2006;66:7999–8006.
    • (2006) Cancer Res , vol.66 , pp. 7999-8006
    • Sengupta, S.1    den Boon, J.A.2    Chen, I.H.3    Newton, M.A.4    Dahl, D.B.5
  • 55
    • 84929133158 scopus 로고    scopus 로고
    • Genome-wide analysis of long non-coding RNA in primary nasopharyngeal carcinoma by microarray
    • PID: 25406670
    • Yang QQ, Deng YF. Genome-wide analysis of long non-coding RNA in primary nasopharyngeal carcinoma by microarray. Histopathology. 2015;66:1022–30.
    • (2015) Histopathology , vol.66 , pp. 1022-1030
    • Yang, Q.Q.1    Deng, Y.F.2
  • 56
    • 84895922399 scopus 로고    scopus 로고
    • Regulation network and expression profiles of Epstein-Barr virus-encoded microRNAs and their potential target host genes in nasopharyngeal carcinomas
    • COI: 1:CAS:528:DC%2BC2cXivVGis7s%3D, PID: 24532457
    • Zeng Z, Huang H, Huang L, Sun M, Yan Q, et al. Regulation network and expression profiles of Epstein-Barr virus-encoded microRNAs and their potential target host genes in nasopharyngeal carcinomas. Sci China Life Sci. 2014;57:315–26.
    • (2014) Sci China Life Sci , vol.57 , pp. 315-326
    • Zeng, Z.1    Huang, H.2    Huang, L.3    Sun, M.4    Yan, Q.5
  • 57
    • 77955413902 scopus 로고    scopus 로고
    • Investigation of IGF2/ApaI and H19/RsaI polymorphisms in patients with cutaneous melanoma
    • COI: 1:CAS:528:DC%2BC3cXpvVejsL4%3D, PID: 20483645
    • Soares MR, Huber J, Rios AF, Ramos ES. Investigation of IGF2/ApaI and H19/RsaI polymorphisms in patients with cutaneous melanoma. Growth Horm IGF Res. 2010;20:295–7.
    • (2010) Growth Horm IGF Res , vol.20 , pp. 295-297
    • Soares, M.R.1    Huber, J.2    Rios, A.F.3    Ramos, E.S.4
  • 59
    • 84861572492 scopus 로고    scopus 로고
    • Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis
    • COI: 1:CAS:528:DC%2BC38XnvFOntbY%3D, PID: 22560814
    • Liu N, Chen NY, Cui RX, Li WF, Li Y, et al. Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol. 2012;13:633–41.
    • (2012) Lancet Oncol , vol.13 , pp. 633-641
    • Liu, N.1    Chen, N.Y.2    Cui, R.X.3    Li, W.F.4    Li, Y.5
  • 60
    • 44449111693 scopus 로고    scopus 로고
    • MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins
    • COI: 1:CAS:528:DC%2BD1cXltVyhtbc%3D, PID: 18390668
    • Sengupta S, den Boon JA, Chen IH, Newton MA, Stanhope SA, et al. MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008;105:5874–8.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 5874-5878
    • Sengupta, S.1    den Boon, J.A.2    Chen, I.H.3    Newton, M.A.4    Stanhope, S.A.5
  • 61
    • 62549160416 scopus 로고    scopus 로고
    • MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BD1MXjt1GjsLk%3D, PID: 19293812
    • Chen HC, Chen GH, Chen YH, Liao WL, Liu CY, et al. MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma. Br J Cancer. 2009;100:1002–11.
    • (2009) Br J Cancer , vol.100 , pp. 1002-1011
    • Chen, H.C.1    Chen, G.H.2    Chen, Y.H.3    Liao, W.L.4    Liu, C.Y.5
  • 62
    • 79953030875 scopus 로고    scopus 로고
    • MicroRNA expression profiling of nasopharyngeal carcinoma
    • PID: 21373758
    • Li T, Chen JX, Fu XP, Yang S, Zhang Z, et al. MicroRNA expression profiling of nasopharyngeal carcinoma. Oncol Rep. 2011;25:1353–63.
    • (2011) Oncol Rep , vol.25 , pp. 1353-1363
    • Li, T.1    Chen, J.X.2    Fu, X.P.3    Yang, S.4    Zhang, Z.5
  • 63
    • 84897019409 scopus 로고    scopus 로고
    • A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis
    • COI: 1:CAS:528:DC%2BC2cXhsVSqsrzE, PID: 24449575
    • Lin J, Huo R, Xiao L, Zhu X, Xie J, et al. A novel p53/microRNA-22/Cyr61 axis in synovial cells regulates inflammation in rheumatoid arthritis. Arthritis Rheumatol. 2014;66:49–59.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 49-59
    • Lin, J.1    Huo, R.2    Xiao, L.3    Zhu, X.4    Xie, J.5
  • 64
    • 84938524828 scopus 로고    scopus 로고
    • A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis
    • COI: 1:CAS:528:DC%2BC2cXks12ns7g%3D, PID: 24662829
    • Subramanian M, Francis P, Bilke S, Li XL, Hara T, et al. A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis. Oncogene. 2015;34:1094–104.
    • (2015) Oncogene , vol.34 , pp. 1094-1104
    • Subramanian, M.1    Francis, P.2    Bilke, S.3    Li, X.L.4    Hara, T.5
  • 65
    • 59949103208 scopus 로고    scopus 로고
    • Effect of recombinant adenovirus-p53 combined with radiotherapy on long-term prognosis of advanced nasopharyngeal carcinoma
    • Pan JJ, Zhang SW, Chen CB, Xiao SW, Sun Y, et al. Effect of recombinant adenovirus-p53 combined with radiotherapy on long-term prognosis of advanced nasopharyngeal carcinoma. J Clin Oncol Off J Am Soc Clin Oncol. 2009;27:799–804.
    • (2009) J Clin Oncol Off J Am Soc Clin Oncol , vol.27 , pp. 799-804
    • Pan, J.J.1    Zhang, S.W.2    Chen, C.B.3    Xiao, S.W.4    Sun, Y.5
  • 66
    • 84892613624 scopus 로고    scopus 로고
    • MiR-22 in tumorigenesis
    • COI: 1:CAS:528:DC%2BC2cXltFertbY%3D, PID: 24231768
    • Song SJ, Pandolfi PP. MiR-22 in tumorigenesis. Cell Cycle. 2014;13:11–2.
    • (2014) Cell Cycle , vol.13 , pp. 11-12
    • Song, S.J.1    Pandolfi, P.P.2
  • 67
    • 33244471340 scopus 로고    scopus 로고
    • The effect of p21 antisense oligodeoxynucleotides on the radiosensitivity of nasopharyngeal carcinoma cells with normal p53 function
    • COI: 1:CAS:528:DC%2BD28XhvVWrtL4%3D, PID: 16448826
    • Liu XF, Xia YF, Li MZ, Wang HM, He YX, et al. The effect of p21 antisense oligodeoxynucleotides on the radiosensitivity of nasopharyngeal carcinoma cells with normal p53 function. Cell Biol Int. 2006;30:283–7.
    • (2006) Cell Biol Int , vol.30 , pp. 283-287
    • Liu, X.F.1    Xia, Y.F.2    Li, M.Z.3    Wang, H.M.4    He, Y.X.5
  • 68
    • 0030053966 scopus 로고    scopus 로고
    • Expression of growth factors, proto-oncogenes, and p53 in nasopharyngeal angiofibromas
    • COI: 1:CAS:528:DyaK2sXkslajuw%3D%3D, PID: 8583852
    • Nagai MA, Butugan O, Logullo A, Brentani MM. Expression of growth factors, proto-oncogenes, and p53 in nasopharyngeal angiofibromas. Laryngoscope. 1996;106:190–5.
    • (1996) Laryngoscope , vol.106 , pp. 190-195
    • Nagai, M.A.1    Butugan, O.2    Logullo, A.3    Brentani, M.M.4
  • 69
    • 84899104417 scopus 로고    scopus 로고
    • DNA damage checkpoints in nasopharyngeal carcinoma
    • COI: 1:CAS:528:DC%2BC2cXhvV2ltbk%3D, PID: 24503238
    • Poon RY. DNA damage checkpoints in nasopharyngeal carcinoma. Oral Oncol. 2014;50:339–44.
    • (2014) Oral Oncol , vol.50 , pp. 339-344
    • Poon, R.Y.1
  • 70
    • 84891798006 scopus 로고    scopus 로고
    • NONCODEv4: exploring the world of long non-coding RNA genes
    • COI: 1:CAS:528:DC%2BC2cXoslKi, PID: 24285305
    • Xie C, Yuan J, Li H, Li M, Zhao G, et al. NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res. 2014;42:D98–103.
    • (2014) Nucleic Acids Res , vol.42 , pp. D98-D103
    • Xie, C.1    Yuan, J.2    Li, H.3    Li, M.4    Zhao, G.5
  • 71
    • 77955323879 scopus 로고    scopus 로고
    • A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
    • COI: 1:CAS:528:DC%2BC3cXpvFKrtrg%3D, PID: 20673990
    • Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 2010;142:409–19.
    • (2010) Cell , vol.142 , pp. 409-419
    • Huarte, M.1    Guttman, M.2    Feldser, D.3    Garber, M.4    Koziol, M.J.5
  • 72
    • 79959756263 scopus 로고    scopus 로고
    • Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
    • COI: 1:CAS:528:DC%2BC3MXntV2qsbY%3D, PID: 21642992
    • Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet. 2011;43:621–9.
    • (2011) Nat Genet , vol.43 , pp. 621-629
    • Hung, T.1    Wang, Y.2    Lin, M.F.3    Koegel, A.K.4    Kotake, Y.5
  • 73
    • 84964217964 scopus 로고    scopus 로고
    • H19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation
    • Liu C, Chen Z, Fang J, Xu A, Zhang W, et al. H19-derived miR-675 contributes to bladder cancer cell proliferation by regulating p53 activation. Tumour Biol. 2015;
    • (2015) Tumour Biol
    • Liu, C.1    Chen, Z.2    Fang, J.3    Xu, A.4    Zhang, W.5
  • 74
    • 84919847631 scopus 로고    scopus 로고
    • H19 promotes pancreatic cancer metastasis by derepressing let-7’s suppression on its target HMGA2-mediated EMT
    • COI: 1:CAS:528:DC%2BC2cXpvFGksbg%3D, PID: 24920070
    • Ma C, Nong K, Zhu H, Wang W, Huang X, et al. H19 promotes pancreatic cancer metastasis by derepressing let-7’s suppression on its target HMGA2-mediated EMT. Tumour Biol. 2014;35:9163–9.
    • (2014) Tumour Biol , vol.35 , pp. 9163-9169
    • Ma, C.1    Nong, K.2    Zhu, H.3    Wang, W.4    Huang, X.5
  • 75
    • 84877270735 scopus 로고    scopus 로고
    • LncRNA loc285194 is a p53-regulated tumor suppressor
    • COI: 1:CAS:528:DC%2BC3sXntVOqtbY%3D, PID: 23558749
    • Liu Q, Huang J, Zhou N, Zhang Z, Zhang A, et al. LncRNA loc285194 is a p53-regulated tumor suppressor. Nucleic Acids Res. 2013;41:4976–87.
    • (2013) Nucleic Acids Res , vol.41 , pp. 4976-4987
    • Liu, Q.1    Huang, J.2    Zhou, N.3    Zhang, Z.4    Zhang, A.5
  • 76
    • 79961170994 scopus 로고    scopus 로고
    • A ceRNA hypothesis: the Rosetta stone of a hidden RNA language?
    • COI: 1:CAS:528:DC%2BC3MXpvFGhs7k%3D, PID: 21802130
    • Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A ceRNA hypothesis: the Rosetta stone of a hidden RNA language? Cell. 2011;146:353–8.
    • (2011) Cell , vol.146 , pp. 353-358
    • Salmena, L.1    Poliseno, L.2    Tay, Y.3    Kats, L.4    Pandolfi, P.P.5
  • 77
    • 84929947023 scopus 로고    scopus 로고
    • Oncocers: ceRNA-mediated cross-talk by sponging miRNAs in oncogenic pathways
    • COI: 1:CAS:528:DC%2BC2MXlslChsbs%3D, PID: 25809705
    • Ergun S, Oztuzcu S. Oncocers: ceRNA-mediated cross-talk by sponging miRNAs in oncogenic pathways. Tumour Biol. 2015;36:3129–36.
    • (2015) Tumour Biol , vol.36 , pp. 3129-3136
    • Ergun, S.1    Oztuzcu, S.2


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