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Volumn 7, Issue 11, 2012, Pages

A Systematic Screen Reveals MicroRNA Clusters That Significantly Regulate Four Major Signaling Pathways

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 200A; MYC PROTEIN; PROTEIN P53; TRANSCRIPTION FACTOR AP 1;

EID: 84869067808     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048474     Document Type: Article
Times cited : (25)

References (61)
  • 1
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V, (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 3
    • 82755189644 scopus 로고    scopus 로고
    • MicroRNA history: discovery, recent applications, and next frontiers
    • Almeida MI, Reis RM, Calin GA, (2011) MicroRNA history: discovery, recent applications, and next frontiers. Mutat Res 717: 1-8.
    • (2011) Mutat Res , vol.717 , pp. 1-8
    • Almeida, M.I.1    Reis, R.M.2    Calin, G.A.3
  • 4
    • 79959918202 scopus 로고    scopus 로고
    • Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis
    • Ma X, Kumar M, Choudhury SN, Becker Buscaglia LE, Barker JR, et al. (2011) Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis. Proc Natl Acad Sci U S A 108: 10144-10149.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10144-10149
    • Ma, X.1    Kumar, M.2    Choudhury, S.N.3    Becker Buscaglia, L.E.4    Barker, J.R.5
  • 5
  • 6
    • 79959315095 scopus 로고    scopus 로고
    • Apoptosis and the target genes of microRNA-21
    • Buscaglia LE, Li Y, (2011) Apoptosis and the target genes of microRNA-21. Chin J Cancer 30: 371-380.
    • (2011) Chin J Cancer , vol.30 , pp. 371-380
    • Buscaglia, L.E.1    Li, Y.2
  • 7
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 33846945735 scopus 로고    scopus 로고
    • Processing of intronic microRNAs
    • Kim YK, Kim VN, (2007) Processing of intronic microRNAs. EMBO J 26: 775-783.
    • (2007) EMBO J , vol.26 , pp. 775-783
    • Kim, Y.K.1    Kim, V.N.2
  • 9
    • 33846053464 scopus 로고    scopus 로고
    • miRGen: a database for the study of animal microRNA genomic organization and function
    • Megraw M, Sethupathy P, Corda B, Hatzigeorgiou AG, (2007) miRGen: a database for the study of animal microRNA genomic organization and function. Nucleic Acids Res 35: D149-155.
    • (2007) Nucleic Acids Res , vol.35
    • Megraw, M.1    Sethupathy, P.2    Corda, B.3    Hatzigeorgiou, A.G.4
  • 10
    • 67249136441 scopus 로고    scopus 로고
    • C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts
    • Bortolin-Cavaille ML, Dance M, Weber M, Cavaille J, (2009) C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts. Nucleic Acids Res 37: 3464-3473.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3464-3473
    • Bortolin-Cavaille, M.L.1    Dance, M.2    Weber, M.3    Cavaille, J.4
  • 11
    • 48449101306 scopus 로고    scopus 로고
    • Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition
    • Cano A, Nieto MA, (2008) Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition. Trends Cell Biol 18: 357-359.
    • (2008) Trends Cell Biol , vol.18 , pp. 357-359
    • Cano, A.1    Nieto, M.A.2
  • 12
    • 80052470207 scopus 로고    scopus 로고
    • Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
    • Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, et al. (2011) Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med 17: 1101-1108.
    • (2011) Nat Med , vol.17 , pp. 1101-1108
    • Korpal, M.1    Ell, B.J.2    Buffa, F.M.3    Ibrahim, T.4    Blanco, M.A.5
  • 13
    • 70349645539 scopus 로고    scopus 로고
    • miR-200 enhances mouse breast cancer cell colonization to form distant metastases
    • Dykxhoorn DM, Wu Y, Xie H, Yu F, Lal A, et al. (2009) miR-200 enhances mouse breast cancer cell colonization to form distant metastases. PLoS One 4: e7181.
    • (2009) PLoS One , vol.4
    • Dykxhoorn, D.M.1    Wu, Y.2    Xie, H.3    Yu, F.4    Lal, A.5
  • 15
    • 63249099917 scopus 로고    scopus 로고
    • Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer
    • Kim YK, Yu J, Han TS, Park SY, Namkoong B, et al. (2009) Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res 37: 1672-1681.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1672-1681
    • Kim, Y.K.1    Yu, J.2    Han, T.S.3    Park, S.Y.4    Namkoong, B.5
  • 16
    • 33846045953 scopus 로고    scopus 로고
    • Principles of microRNA regulation of a human cellular signaling network
    • Cui Q, Yu Z, Purisima EO, Wang E, (2006) Principles of microRNA regulation of a human cellular signaling network. Mol Syst Biol 2: 46.
    • (2006) Mol Syst Biol , vol.2 , pp. 46
    • Cui, Q.1    Yu, Z.2    Purisima, E.O.3    Wang, E.4
  • 17
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis, and metabolism
    • Dang CV, (1999) c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol 19: 1-11.
    • (1999) Mol Cell Biol , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 18
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of NF-kappaB subunits in cancer
    • Perkins ND, (2012) The diverse and complex roles of NF-kappaB subunits in cancer. Nat Rev Cancer 12: 121-132.
    • (2012) Nat Rev Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 19
    • 84859171807 scopus 로고    scopus 로고
    • MYC on the Path to Cancer
    • Dang CV, (2012) MYC on the Path to Cancer. Cell 149: 22-35.
    • (2012) Cell , vol.149 , pp. 22-35
    • Dang, C.V.1
  • 20
    • 77949916262 scopus 로고    scopus 로고
    • AP-1-The Jun proteins: Oncogenes or tumor suppressors in disguise
    • Shaulian E, (2010) AP-1-The Jun proteins: Oncogenes or tumor suppressors in disguise? Cell Signal 22: 894-899.
    • (2010) Cell Signal , vol.22 , pp. 894-899
    • Shaulian, E.1
  • 21
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the Light: The Growing Complexity of p53
    • Vousden KH, Prives C, (2009) Blinded by the Light: The Growing Complexity of p53. Cell 137: 413-431.
    • (2009) Cell , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 22
    • 68649113121 scopus 로고    scopus 로고
    • The p53 Pathway Encounters the MicroRNA World
    • Takwi A, Li Y, (2009) The p53 Pathway Encounters the MicroRNA World. Curr Genomics 10: 194-197.
    • (2009) Curr Genomics , vol.10 , pp. 194-197
    • Takwi, A.1    Li, Y.2
  • 24
    • 54049156472 scopus 로고    scopus 로고
    • Control of cell proliferation pathways by microRNAs
    • Bueno MJ, Perez de Castro I, Malumbres M, (2008) Control of cell proliferation pathways by microRNAs. Cell Cycle 7: 3143-3148.
    • (2008) Cell Cycle , vol.7 , pp. 3143-3148
    • Bueno, M.J.1    Perez de Castro, I.2    Malumbres, M.3
  • 25
    • 68749094048 scopus 로고    scopus 로고
    • Translational regulation mechanisms of AP-1 proteins
    • Vesely PW, Staber PB, Hoefler G, Kenner L, (2009) Translational regulation mechanisms of AP-1 proteins. Mutat Res 682: 7-12.
    • (2009) Mutat Res , vol.682 , pp. 7-12
    • Vesely, P.W.1    Staber, P.B.2    Hoefler, G.3    Kenner, L.4
  • 26
    • 78650858038 scopus 로고    scopus 로고
    • miR-301a as an NF-kB activator in pancreatic cancer cells
    • Lu Z, Li Y, Takwi A, Li B, Zhang J, et al. (2011) miR-301a as an NF-kB activator in pancreatic cancer cells. EMBO J 30: 57-67.
    • (2011) EMBO J , vol.30 , pp. 57-67
    • Lu, Z.1    Li, Y.2    Takwi, A.3    Li, B.4    Zhang, J.5
  • 27
    • 0030747725 scopus 로고    scopus 로고
    • Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals
    • Sears R, Ohtani K, Nevins JR, (1997) Identification of positively and negatively acting elements regulating expression of the E2F2 gene in response to cell growth signals. Mol Cell Biol 17: 5227-5235.
    • (1997) Mol Cell Biol , vol.17 , pp. 5227-5235
    • Sears, R.1    Ohtani, K.2    Nevins, J.R.3
  • 28
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • Kumar M, Lu Z, Takwi AAL, Chen W, Callander NS, et al. (2011) Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene 30: 843-853.
    • (2011) Oncogene , vol.30 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.L.3    Chen, W.4    Callander, N.S.5
  • 30
    • 84865730529 scopus 로고    scopus 로고
    • A Statin-regulated MicroRNA Represses Human c-Myc Expression and Function
    • In Press
    • Takwi A, Li Y, Buscaglia L, Zhang J, Choudhury S, et al. (2012) A Statin-regulated MicroRNA Represses Human c-Myc Expression and Function. EMBO Mol Med In Press.
    • (2012) EMBO Mol Med
    • Takwi, A.1    Li, Y.2    Buscaglia, L.3    Zhang, J.4    Choudhury, S.5
  • 31
    • 12344252237 scopus 로고    scopus 로고
    • AP-1 subunits: quarrel and harmony among siblings
    • Hess J, Angel P, Schorpp-Kistner M, (2004) AP-1 subunits: quarrel and harmony among siblings. J Cell Sci 117: 5965-5973.
    • (2004) J Cell Sci , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 32
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel P, Karin M, (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072: 129-157.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 34
    • 84865119431 scopus 로고    scopus 로고
    • MicroRNA-10a is Overexpressed in Human Pancreatic Cancer and Involved in Its Invasiveness Partially via Suppression of the HOXA1 Gene
    • Ohuchida K, Mizumoto K, Lin C, Yamaguchi H, Ohtsuka T, et al. (2012) MicroRNA-10a is Overexpressed in Human Pancreatic Cancer and Involved in Its Invasiveness Partially via Suppression of the HOXA1 Gene. Ann Surg Oncol.
    • (2012) Ann Surg Oncol
    • Ohuchida, K.1    Mizumoto, K.2    Lin, C.3    Yamaguchi, H.4    Ohtsuka, T.5
  • 35
    • 70649104670 scopus 로고    scopus 로고
    • Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer
    • Weiss FU, Marques IJ, Woltering JM, Vlecken DH, Aghdassi A, et al. (2009) Retinoic acid receptor antagonists inhibit miR-10a expression and block metastatic behavior of pancreatic cancer. Gastroenterology 137: 2136-2145 e2131-2137.
    • (2009) Gastroenterology , vol.137
    • Weiss, F.U.1    Marques, I.J.2    Woltering, J.M.3    Vlecken, D.H.4    Aghdassi, A.5
  • 36
    • 84857136301 scopus 로고    scopus 로고
    • miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death
    • Bryant A, Palma CA, Jayaswal V, Yang YW, Lutherborrow M, et al. (2012) miR-10a is aberrantly overexpressed in Nucleophosmin1 mutated acute myeloid leukaemia and its suppression induces cell death. Mol Cancer 11: 8.
    • (2012) Mol Cancer , vol.11 , pp. 8
    • Bryant, A.1    Palma, C.A.2    Jayaswal, V.3    Yang, Y.W.4    Lutherborrow, M.5
  • 37
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M, (2006) Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 38
    • 84861206450 scopus 로고    scopus 로고
    • MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)
    • Kim SW, Ramasamy K, Bouamar H, Lin AP, Jiang D, et al. (2012) MicroRNAs miR-125a and miR-125b constitutively activate the NF-kappaB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20). Proc Natl Acad Sci U S A 109: 7865-7870.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 7865-7870
    • Kim, S.W.1    Ramasamy, K.2    Bouamar, H.3    Lin, A.P.4    Jiang, D.5
  • 39
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ, (2008) Reflecting on 25 years with MYC. Nat Rev Cancer 8: 976-990.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 40
    • 0034703742 scopus 로고    scopus 로고
    • p53: death star
    • Vousden KH, (2000) p53: death star. Cell 103: 691-694.
    • (2000) Cell , vol.103 , pp. 691-694
    • Vousden, K.H.1
  • 41
    • 0034818446 scopus 로고    scopus 로고
    • Post-translational modifications and activation of p53 by genotoxic stresses
    • Appella E, Anderson CW, (2001) Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 268: 2764-2772.
    • (2001) Eur J Biochem , vol.268 , pp. 2764-2772
    • Appella, E.1    Anderson, C.W.2
  • 42
    • 77956164185 scopus 로고    scopus 로고
    • The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta
    • Noguer-Dance M, Abu-Amero S, Al-Khtib M, Lefevre A, Coullin P, et al. (2010) The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta. Hum Mol Genet 19: 3566-3582.
    • (2010) Hum Mol Genet , vol.19 , pp. 3566-3582
    • Noguer-Dance, M.1    Abu-Amero, S.2    Al-Khtib, M.3    Lefevre, A.4    Coullin, P.5
  • 43
    • 67651097924 scopus 로고    scopus 로고
    • Intrauterine growth restriction, human placental development and trophoblast cell death
    • Scifres CM, Nelson DM, (2009) Intrauterine growth restriction, human placental development and trophoblast cell death. J Physiol 587: 3453-3458.
    • (2009) J Physiol , vol.587 , pp. 3453-3458
    • Scifres, C.M.1    Nelson, D.M.2
  • 44
    • 0036583261 scopus 로고    scopus 로고
    • Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression
    • Levy R, Smith SD, Yusuf K, Huettner PC, Kraus FT, et al. (2002) Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression. Am J Obstet Gynecol 186: 1056-1061.
    • (2002) Am J Obstet Gynecol , vol.186 , pp. 1056-1061
    • Levy, R.1    Smith, S.D.2    Yusuf, K.3    Huettner, P.C.4    Kraus, F.T.5
  • 45
    • 41649091906 scopus 로고    scopus 로고
    • The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E, Peter ME, (2008) The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22: 894-907.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 46
    • 65349162096 scopus 로고    scopus 로고
    • Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression
    • Peter ME, (2009) Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle 8: 843-852.
    • (2009) Cell Cycle , vol.8 , pp. 843-852
    • Peter, M.E.1
  • 47
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, et al. (2008) A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 68: 7846-7854.
    • (2008) Cancer Res , vol.68 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5
  • 48
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP, (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 49
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, et al. (2008) A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9: 582-589.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5
  • 50
    • 84864966395 scopus 로고    scopus 로고
    • MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma
    • Kurashige J, Kamohara H, Watanabe M, Hiyoshi Y, Iwatsuki M, et al. (2012) MicroRNA-200b Regulates Cell Proliferation, Invasion, and Migration by Directly Targeting ZEB2 in Gastric Carcinoma. Ann Surg Oncol.
    • (2012) Ann Surg Oncol
    • Kurashige, J.1    Kamohara, H.2    Watanabe, M.3    Hiyoshi, Y.4    Iwatsuki, M.5
  • 51
    • 72649103295 scopus 로고    scopus 로고
    • miR-200 de-FOGs insulin signaling
    • Teleman AA, (2010) miR-200 de-FOGs insulin signaling. Cell Metab 11: 8-9.
    • (2010) Cell Metab , vol.11 , pp. 8-9
    • Teleman, A.A.1
  • 52
    • 71149108895 scopus 로고    scopus 로고
    • Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K
    • Hyun S, Lee JH, Jin H, Nam J, Namkoong B, et al. (2009) Conserved MicroRNA miR-8/miR-200 and its target USH/FOG2 control growth by regulating PI3K. Cell 139: 1096-1108.
    • (2009) Cell , vol.139 , pp. 1096-1108
    • Hyun, S.1    Lee, J.H.2    Jin, H.3    Nam, J.4    Namkoong, B.5
  • 53
    • 0030696171 scopus 로고    scopus 로고
    • p53 expression overcomes p21WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells
    • Kagawa S, Fujiwara T, Hizuta A, Yasuda T, Zhang WW, et al. (1997) p53 expression overcomes p21WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells. Oncogene 15: 1903-1909.
    • (1997) Oncogene , vol.15 , pp. 1903-1909
    • Kagawa, S.1    Fujiwara, T.2    Hizuta, A.3    Yasuda, T.4    Zhang, W.W.5
  • 54
    • 0029914174 scopus 로고    scopus 로고
    • Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene
    • Fries KL, Miller WE, Raab-Traub N, (1996) Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. J Virol 70: 8653-8659.
    • (1996) J Virol , vol.70 , pp. 8653-8659
    • Fries, K.L.1    Miller, W.E.2    Raab-Traub, N.3
  • 55
    • 0029802591 scopus 로고    scopus 로고
    • p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen X, Ko LJ, Jayaraman L, Prives C, (1996) p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev 10: 2438-2451.
    • (1996) Genes Dev , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 56
    • 77955661579 scopus 로고    scopus 로고
    • MicroRNA-21 in cardiovascular disease
    • Cheng Y, Zhang C, (2010) MicroRNA-21 in cardiovascular disease. J Cardiovasc Transl Res 3: 251-255.
    • (2010) J Cardiovasc Transl Res , vol.3 , pp. 251-255
    • Cheng, Y.1    Zhang, C.2
  • 57
    • 45749124784 scopus 로고    scopus 로고
    • A computational screen for mouse signaling pathways targeted by microRNA clusters
    • Xu J, Wong C, (2008) A computational screen for mouse signaling pathways targeted by microRNA clusters. RNA 14: 1276-1283.
    • (2008) RNA , vol.14 , pp. 1276-1283
    • Xu, J.1    Wong, C.2
  • 58
    • 68349092641 scopus 로고    scopus 로고
    • Clustered microRNAs' coordination in regulating protein-protein interaction network
    • Yuan X, Liu C, Yang P, He S, Liao Q, et al. (2009) Clustered microRNAs' coordination in regulating protein-protein interaction network. BMC Syst Biol 3: 65.
    • (2009) BMC Syst Biol , vol.3 , pp. 65
    • Yuan, X.1    Liu, C.2    Yang, P.3    He, S.4    Liao, Q.5
  • 59
    • 28944439309 scopus 로고    scopus 로고
    • Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution
    • Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM, (2005) Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution. Cell 123: 1133-1146.
    • (2005) Cell , vol.123 , pp. 1133-1146
    • Stark, A.1    Brennecke, J.2    Bushati, N.3    Russell, R.B.4    Cohen, S.M.5
  • 60
    • 77956813422 scopus 로고    scopus 로고
    • Regulation of Myc by miR-34c: A mechanism to prevent genomic instability
    • Cannell IG, Bushell M, (2010) Regulation of Myc by miR-34c: A mechanism to prevent genomic instability? Cell Cycle 9: 2726-2730.
    • (2010) Cell Cycle , vol.9 , pp. 2726-2730
    • Cannell, I.G.1    Bushell, M.2
  • 61
    • 51349093465 scopus 로고    scopus 로고
    • MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis
    • Pichiorri F, Suh SS, Ladetto M, Kuehl M, Palumbo T, et al. (2008) MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc Natl Acad Sci USA 105: 12885-12890.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 12885-12890
    • Pichiorri, F.1    Suh, S.S.2    Ladetto, M.3    Kuehl, M.4    Palumbo, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.