메뉴 건너뛰기




Volumn 121, Issue 22, 2013, Pages 4529-4540

Single nucleotide variation in the TP53 3′ untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: A report from the International DLBCL Rituximab-CHOP Consortium Program

(29)  Li, Yong a,b   Gordon, Michael W a   Xu Monette, Zijun Y b   Visco, Carlo c   Tzankov, Alexander d   Zou, Dehui e   Qiu, Lugui e   Montes Moreno, Santiago f   Dybkaer, Karen g   Orazi, Attilio h   Zu, Youli i   Bhagat, Govind j   Richards, Kristy L k   Hsi, Eric D l   Choi, William W L m   Van Krieken, J Han n   Huang, Qin o   Ai, Weiyun p   Ponzoni, Maurilio q   Ferreri, Andrés J M q   more..


Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; MICRORNA 125B; PREDNISONE; PROTEIN P53; RITUXIMAB; VINCRISTINE; ANTINEOPLASTIC AGENT; MICRORNA; MONOCLONAL ANTIBODY; TP53 PROTEIN, HUMAN;

EID: 84880857890     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-471722     Document Type: Article
Times cited : (40)

References (50)
  • 1
    • 33846899456 scopus 로고    scopus 로고
    • Restoration of p53 function leads to tumour regression in vivo
    • Ventura A, Kirsch DG, McLaughlin ME, et al. Restoration of p53 function leads to tumour regression in vivo. Nature. 2007;445(7128):661-665.
    • (2007) Nature , vol.445 , Issue.7128 , pp. 661-665
    • Ventura, A.1    Kirsch, D.G.2    McLaughlin, M.E.3
  • 2
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • Xue W, Zender L, Miething C, et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature. 2007;445(7128):656-660.
    • (2007) Nature , vol.445 , Issue.7128 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3
  • 5
  • 6
    • 10944236962 scopus 로고    scopus 로고
    • Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
    • Olive KP, Tuveson DA, Ruhe ZC, et al. Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell. 2004;119(6): 847-860.
    • (2004) Cell. , vol.119 , Issue.6 , pp. 847-860
    • Olive, K.P.1    Tuveson, D.A.2    Ruhe, Z.C.3
  • 7
    • 13644260907 scopus 로고    scopus 로고
    • Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
    • Lang GA, Iwakuma T, Suh YA, et al. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell. 2004; 119(6):861-872.
    • (2004) Cell. , vol.119 , Issue.6 , pp. 861-872
    • Lang, G.A.1    Iwakuma, T.2    Suh, Y.A.3
  • 8
    • 7144250518 scopus 로고    scopus 로고
    • Role of a p53 polymorphism in the development of human papillomavirus-associated cancer
    • Storey A, Thomas M, Kalita A, et al. Role of a p53 polymorphism in the development of human papillomavirus-associated cancer. Nature. 1998; 393(6682):229-234.
    • (1998) Nature , vol.393 , Issue.6682 , pp. 229-234
    • Storey, A.1    Thomas, M.2    Kalita, A.3
  • 9
    • 77951010885 scopus 로고    scopus 로고
    • Aggressive lymphomas
    • Lenz G, Staudt LM. Aggressive lymphomas. N Engl J Med. 2010;362(15):1417-1429.
    • (2010) N Engl J Med. , vol.362 , Issue.15 , pp. 1417-1429
    • Lenz, G.1    Staudt, L.M.2
  • 10
    • 79955835059 scopus 로고    scopus 로고
    • Pathogenesis of non-Hodgkin's lymphoma
    • Nogai H, Dörken B, Lenz G. Pathogenesis of non-Hodgkin's lymphoma. J Clin Oncol. 2011;29(14): 1803-1811.
    • (2011) J Clin Oncol. , vol.29 , Issue.14 , pp. 1803-1811
    • Nogai, H.1    Dörken, B.2    Lenz, G.3
  • 11
    • 80052269038 scopus 로고    scopus 로고
    • Analysis of the coding genome of diffuse large B-cell lymphoma
    • Pasqualucci L, Trifonov V, Fabbri G, et al. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet. 2011;43(9):830-837.
    • (2011) Nat Genet. , vol.43 , Issue.9 , pp. 830-837
    • Pasqualucci, L.1    Trifonov, V.2    Fabbri, G.3
  • 12
    • 80052029516 scopus 로고    scopus 로고
    • Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
    • Morin RD, Mendez-Lago M, Mungall AJ, et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature. 2011;476(7360): 298-303.
    • (2011) Nature , vol.476 , Issue.7360 , pp. 298-303
    • Morin, R.D.1    Mendez-Lago, M.2    Mungall, A.J.3
  • 13
    • 84857942952 scopus 로고    scopus 로고
    • Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
    • Lohr JG, Stojanov P, Lawrence MS, et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci USA. 2012;109(10):3879-3884.
    • (2012) Proc Natl Acad Sci USA. , vol.109 , Issue.10 , pp. 3879-3884
    • Lohr, J.G.1    Stojanov, P.2    Lawrence, M.S.3
  • 14
    • 0034676455 scopus 로고    scopus 로고
    • Surfing the p53 network
    • Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature. 2000;408(6810):307-310.
    • (2000) Nature , vol.408 , Issue.6810 , pp. 307-310
    • Vogelstein, B.1    Lane, D.2    Levine, A.J.3
  • 15
    • 79952699255 scopus 로고    scopus 로고
    • P53: The most frequently altered gene in human cancers
    • Vogelstein B, Sur S, Prives C. p53: the most frequently altered gene in human cancers. Nature Education. 2010;3(9):6.
    • (2010) Nature Education. , vol.3 , Issue.9 , pp. 6
    • Vogelstein, B.1    Sur, S.2    Prives, C.3
  • 16
    • 54049126176 scopus 로고    scopus 로고
    • Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: An international collaborative study
    • Young KH, Leroy K, Møller MB, et al. Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. Blood. 2008; 112(8):3088-3098.
    • (2008) Blood , vol.112 , Issue.8 , pp. 3088-3098
    • Young, K.H.1    Leroy, K.2    Møller, M.B.3
  • 17
    • 84868602463 scopus 로고    scopus 로고
    • Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: Report from an International DLBCL Rituximab-CHOP Consortium Program Study
    • Xu-Monette ZY, Wu L, Visco C, et al. Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study. Blood. 2012;120(19):3986-3996.
    • (2012) Blood , vol.120 , Issue.19 , pp. 3986-3996
    • Xu-Monette, Z.Y.1    Wu, L.2    Visco, C.3
  • 18
    • 78650858038 scopus 로고    scopus 로고
    • MiR-301a as an NF-kB activator in pancreatic cancer cells
    • Lu Z, Li Y, Takwi A, et al. miR-301a as an NF-kB activator in pancreatic cancer cells. EMBO J. 2011;30(1):57-67.
    • (2011) EMBO J. , vol.30 , Issue.1 , pp. 57-67
    • Lu, Z.1    Li, Y.2    Takwi, A.3
  • 19
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • Petitjean A, Mathe E, Kato S, et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat. 2007;28(6):622-629.
    • (2007) Hum Mutat. , vol.28 , Issue.6 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3
  • 20
    • 79951812882 scopus 로고    scopus 로고
    • Negative regulation of the tumor suppressor p53 gene by microRNAs
    • Kumar M, Lu Z, Takwi AAL, et al. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene. 2011;30(7):843-853.
    • (2011) Oncogene. , vol.30 , Issue.7 , pp. 843-853
    • Kumar, M.1    Lu, Z.2    Takwi, A.A.L.3
  • 21
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • Le MTN, Teh C, Shyh-Chang N, et al. MicroRNA-125b is a novel negative regulator of p53. Genes Dev. 2009;23(7):862-876.
    • (2009) Genes Dev. , vol.23 , Issue.7 , pp. 862-876
    • Le, M.T.N.1    Teh, C.2    Shyh-Chang, N.3
  • 22
    • 77953096272 scopus 로고    scopus 로고
    • Negative regulation of tumor suppressor p53 by microRNA miR-504
    • Hu W, Chan CS, Wu R, et al. Negative regulation of tumor suppressor p53 by microRNA miR-504. Mol Cell. 2010;38(5):689-699.
    • (2010) Mol Cell. , vol.38 , Issue.5 , pp. 689-699
    • Hu, W.1    Chan, C.S.2    Wu, R.3
  • 23
    • 77957764089 scopus 로고    scopus 로고
    • MiR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma
    • Swarbrick A, Woods SL, Shaw A, et al. miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma. Nat Med. 2010;16(10):1134-1140.
    • (2010) Nat Med. , vol.16 , Issue.10 , pp. 1134-1140
    • Swarbrick, A.1    Woods, S.L.2    Shaw, A.3
  • 24
    • 78649644924 scopus 로고    scopus 로고
    • MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states
    • Neveu P, Kye MJ, Qi S, et al. MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 2010;7(6): 671-681.
    • (2010) Cell Stem Cell. , vol.7 , Issue.6 , pp. 671-681
    • Neveu, P.1    Kye, M.J.2    Qi, S.3
  • 25
    • 84869067808 scopus 로고    scopus 로고
    • A systematic screen reveals MicroRNA clusters that significantly regulate four major signaling pathways
    • Becker LE, Lu Z, Chen W, Xiong W, Kong M, Li Y. A systematic screen reveals MicroRNA clusters that significantly regulate four major signaling pathways. PLoS ONE. 2012;7(11):e48474.
    • (2012) PLoS ONE. , vol.7 , Issue.11 , pp. e48474
    • Becker, L.E.1    Lu, Z.2    Chen, W.3    Xiong, W.4    Kong, M.5    Li, Y.6
  • 26
    • 77952875310 scopus 로고    scopus 로고
    • MicroRNA-1285 inhibits the expression of p53 by directly targeting its 39 untranslated region
    • Tian S, Huang S, Wu S, Guo W, Li J, He X. MicroRNA-1285 inhibits the expression of p53 by directly targeting its 39 untranslated region. Biochem Biophys Res Commun. 2010;396(2): 435-439.
    • (2010) Biochem Biophys Res Commun. , vol.396 , Issue.2 , pp. 435-439
    • Tian, S.1    Huang, S.2    Wu, S.3    Guo, W.4    Li, J.5    He, X.6
  • 27
    • 78650861867 scopus 로고    scopus 로고
    • Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia
    • Fabbri M, Bottoni A, Shimizu M, et al. Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia. JAMA. 2011;305(1):59-67.
    • (2011) JAMA , vol.305 , Issue.1 , pp. 59-67
    • Fabbri, M.1    Bottoni, A.2    Shimizu, M.3
  • 28
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK-H, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009;19(1):92-105.
    • (2009) Genome Res. , vol.19 , Issue.1 , pp. 92-105
    • Friedman, R.C.1    Kk-H, F.2    Burge, C.B.3    Bartel, D.P.4
  • 29
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215-233.
    • (2009) Cell. , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 30
    • 80055009292 scopus 로고    scopus 로고
    • A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
    • Stacey SN, Sulem P, Jonasdottir A, et al. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet. 2011;43(11):1098-1103.
    • (2011) Nat Genet. , vol.43 , Issue.11 , pp. 1098-1103
    • Stacey, S.N.1    Sulem, P.2    Jonasdottir, A.3
  • 31
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C, Bartel DP. Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell. 2009;138(4):673-684.
    • (2009) Cell. , vol.138 , Issue.4 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 32
    • 61749103876 scopus 로고    scopus 로고
    • Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer
    • Topisirovic I, Siddiqui N, Orolicki S, et al. Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. Mol Cell Biol. 2009;29(5): 1152-1162.
    • (2009) Mol Cell Biol. , vol.29 , Issue.5 , pp. 1152-1162
    • Topisirovic, I.1    Siddiqui, N.2    Orolicki, S.3
  • 33
    • 70349320158 scopus 로고    scopus 로고
    • Causes and consequences of microRNA dysregulation in cancer
    • Croce CM. Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet. 2009;10(10):704-714.
    • (2009) Nat Rev Genet. , vol.10 , Issue.10 , pp. 704-714
    • Croce, C.M.1
  • 34
    • 37549015263 scopus 로고    scopus 로고
    • Germinal centres: Role in B-cell physiology and malignancy
    • Klein U, Dalla-Favera R. Germinal centres: role in B-cell physiology and malignancy. Nat Rev Immunol. 2008;8(1):22-33.
    • (2008) Nat Rev Immunol. , vol.8 , Issue.1 , pp. 22-33
    • Klein, U.1    Dalla-Favera, R.2
  • 35
    • 33644876453 scopus 로고    scopus 로고
    • SNP500Cancer: A public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes
    • Packer BR, Yeager M, Burdett L, et al. SNP500Cancer: a public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes. Nucleic Acids Res. 2006;34(Database issue suppl 1):D617-D621.
    • (2006) Nucleic Acids Res. , vol.34 , Issue.DATABASE ISSUE , pp. D617-D621
    • Packer, B.R.1    Yeager, M.2    Burdett, L.3
  • 36
    • 80055009292 scopus 로고    scopus 로고
    • A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
    • Stacey SN, Sulem P, Jonasdottir A, et al. Swedish Low-risk Colorectal Cancer Study Group. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. Nat Genet. 2011;43(11):1098-1103.
    • (2011) Nat Genet. , vol.43 , Issue.11 , pp. 1098-1103
    • Stacey, S.N.1    Sulem, P.2    Jonasdottir, A.3
  • 37
    • 84866028455 scopus 로고    scopus 로고
    • Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma
    • Monti S, Chapuy B, Takeyama K, et al. Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma. Cancer Cell. 2012;22(3):359-372.
    • (2012) Cancer Cell. , vol.22 , Issue.3 , pp. 359-372
    • Monti, S.1    Chapuy, B.2    Takeyama, K.3
  • 38
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P, Rusu M, Sheridan R, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell. 2007;129(7): 1401-1414.
    • (2007) Cell. , vol.129 , Issue.7 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 39
    • 77957252821 scopus 로고    scopus 로고
    • Comprehensive microRNA expression profiling of the hematopoietic hierarchy
    • Petriv OI, Kuchenbauer F, Delaney AD, et al. Comprehensive microRNA expression profiling of the hematopoietic hierarchy. Proc Natl Acad Sci USA. 2010;107(35):15443-15448.
    • (2010) Proc Natl Acad Sci USA. , vol.107 , Issue.35 , pp. 15443-15448
    • Petriv, O.I.1    Kuchenbauer, F.2    Delaney, A.D.3
  • 40
    • 79956089851 scopus 로고    scopus 로고
    • Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage
    • Spierings DC, McGoldrick D, Hamilton-Easton AM, et al. Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage. Blood. 2011; 117(20):5340-5349.
    • (2011) Blood , vol.117 , Issue.20 , pp. 5340-5349
    • Spierings, D.C.1    McGoldrick, D.2    Hamilton-Easton, A.M.3
  • 41
    • 66549101276 scopus 로고    scopus 로고
    • Patterns of microRNA expression characterize stages of human B-cell differentiation
    • Zhang J, Jima DD, Jacobs C, et al. Patterns of microRNA expression characterize stages of human B-cell differentiation. Blood. 2009;113(19): 4586-4594.
    • (2009) Blood , vol.113 , Issue.19 , pp. 4586-4594
    • Zhang, J.1    Jima, D.D.2    Jacobs, C.3
  • 42
    • 65549112644 scopus 로고    scopus 로고
    • Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas
    • Malumbres R, Sarosiek KA, Cubedo E, et al. Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas. Blood. 2009;113(16): 3754-3764.
    • (2009) Blood , vol.113 , Issue.16 , pp. 3754-3764
    • Malumbres, R.1    Sarosiek, K.A.2    Cubedo, E.3
  • 43
    • 26244459242 scopus 로고    scopus 로고
    • Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin
    • Takagi M, Absalon MJ, McLure KG, Kastan MB. Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell. 2005;123(1):49-63.
    • (2005) Cell. , vol.123 , Issue.1 , pp. 49-63
    • Takagi, M.1    Absalon, M.J.2    McLure, K.G.3    Kastan, M.B.4
  • 44
    • 0038153919 scopus 로고    scopus 로고
    • RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation
    • Mazan-Mamczarz K, Galbán S, López de Silanes I, et al. RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci USA. 2003; 100(14):8354-8359.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , Issue.14 , pp. 8354-8359
    • Mazan-Mamczarz, K.1    Galbán, S.2    López De Silanes, I.3
  • 45
    • 84885708564 scopus 로고    scopus 로고
    • Genetic abnormalities in multiple myeloma
    • Kumar S, Abraham J, eds. New York, NY: Demos Medical Publishing
    • Chng WJ. Genetic abnormalities in multiple myeloma. In: Kumar S, Abraham J, eds. Multiple Myeloma. New York, NY: Demos Medical Publishing; 2010:215-236.
    • (2010) Multiple Myeloma , pp. 215-236
    • Chng, W.J.1
  • 46
    • 23944469845 scopus 로고    scopus 로고
    • Recent developments in genomewide association scans: A workshop summary and review
    • Thomas DC, Haile RW, Duggan D. Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet. 2005;77(3):337-345.
    • (2005) Am J Hum Genet. , vol.77 , Issue.3 , pp. 337-345
    • Thomas, D.C.1    Haile, R.W.2    Duggan, D.3
  • 47
    • 84864538649 scopus 로고    scopus 로고
    • A functional germline variant in the P53 polyadenylation signal and risk of esophageal squamous cell carcinoma
    • Zhou L, Yuan Q, Yang M. A functional germline variant in the P53 polyadenylation signal and risk of esophageal squamous cell carcinoma. Gene. 2012;506(2):295-297.
    • (2012) Gene. , vol.506 , Issue.2 , pp. 295-297
    • Zhou, L.1    Yuan, Q.2    Yang, M.3
  • 48
    • 84864315118 scopus 로고    scopus 로고
    • Rare TP53 genetic variant associated with glioma risk and outcome
    • Egan KM, Nabors LB, Olson JJ, et al. Rare TP53 genetic variant associated with glioma risk and outcome. J Med Genet. 2012;49(7):420-421.
    • (2012) J Med Genet. , vol.49 , Issue.7 , pp. 420-421
    • Egan, K.M.1    Nabors, L.B.2    Olson, J.J.3
  • 49
    • 0021673231 scopus 로고
    • Role of the conserved AAUAAA sequence: Four AAUAAA point mutants prevent messenger RNA 39 end formation
    • Wickens M, Stephenson P. Role of the conserved AAUAAA sequence: four AAUAAA point mutants prevent messenger RNA 39 end formation. Science. 1984;226(4678):1045-1051.
    • (1984) Science. , vol.226 , Issue.4678 , pp. 1045-1051
    • Wickens, M.1    Stephenson, P.2
  • 50
    • 0022751114 scopus 로고
    • The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro
    • Zarkower D, Stephenson P, Sheets M, Wickens M. The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro. Mol Cell Biol. 1986;6(7): 2317-2323.
    • (1986) Mol Cell Biol. , vol.6 , Issue.7 , pp. 2317-2323
    • Zarkower, D.1    Stephenson, P.2    Sheets, M.3    Wickens, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.