메뉴 건너뛰기




Volumn 34, Issue 9, 2015, Pages 1094-1104

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA LET 7I; PROTEIN P53; PROTEIN P63; UNCLASSIFIED DRUG; MIRNLET7 MICRORNA, HUMAN; SMALL INTERFERING RNA; TP53 PROTEIN, HUMAN; TP63 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

EID: 84938524828     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.46     Document Type: Article
Times cited : (63)

References (56)
  • 1
    • 30344478870 scopus 로고    scopus 로고
    • A global map of p53 transcription-factor binding sites in the human genome
    • Wei CL, Wu Q, Vega VB, Chiu KP, Ng P, Zhang T et al. A global map of p53 transcription-factor binding sites in the human genome. Cell 2006;124:207-219.
    • (2006) Cell , vol.124 , pp. 207-219
    • Wei, C.L.1    Wu, Q.2    Vega, V.B.3    Chiu, K.P.4    Ng, P.5    Zhang, T.6
  • 2
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002;2:594-604.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 3
    • 84862636275 scopus 로고    scopus 로고
    • Mutant p53: One name, many proteins
    • Freed-Pastor WA, Prives C. Mutant p53: one name, many proteins. Genes Dev 2012;26:1268-1286.
    • (2012) Genes Dev , vol.26 , pp. 1268-1286
    • Freed-Pastor, W.A.1    Prives, C.2
  • 7
    • 63049136592 scopus 로고    scopus 로고
    • A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B et al. A mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 2009;137:87-98.
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2    Montagner, M.3    Dupont, S.4    Wong, C.5    Hann, B.6
  • 11
    • 83255185781 scopus 로고    scopus 로고
    • TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73
    • Liu K, Ling S, Lin WC. TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73. Mol Cell Biol 2011;31:4464-4481.
    • (2011) Mol Cell Biol , vol.31 , pp. 4464-4481
    • Liu, K.1    Ling, S.2    Lin, W.C.3
  • 12
    • 33748211158 scopus 로고    scopus 로고
    • Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation
    • Di Agostino S, Strano S, Emiliozzi V, Zerbini V, Mottolese M, Sacchi A et al. Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation. Cancer Cell 2006;10:191-202.
    • (2006) Cancer Cell , vol.10 , pp. 191-202
    • Di Agostino, S.1    Strano, S.2    Emiliozzi, V.3    Zerbini, V.4    Mottolese, M.5    Sacchi, A.6
  • 13
    • 0033215387 scopus 로고    scopus 로고
    • Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
    • Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ et al. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 1999;13:2490-2501.
    • (1999) Genes Dev , vol.13 , pp. 2490-2501
    • Murphy, M.1    Ahn, J.2    Walker, K.K.3    Hoffman, W.H.4    Evans, R.M.5    Levine, A.J.6
  • 14
    • 0035914335 scopus 로고    scopus 로고
    • Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1
    • Sampath J, Sun D, Kidd VJ, Grenet J, Gandhi A, Shapiro LH et al. Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1. J Biol Chem 2001;276:39359-39367.
    • (2001) J Biol Chem , vol.276 , pp. 39359-39367
    • Sampath, J.1    Sun, D.2    Kidd, V.J.3    Grenet, J.4    Gandhi, A.5    Shapiro, L.H.6
  • 15
    • 34047223196 scopus 로고    scopus 로고
    • Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?
    • Li Y, Prives C. Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? Oncogene 2007;26:2220-2225.
    • (2007) Oncogene , vol.26 , pp. 2220-2225
    • Li, Y.1    Prives, C.2
  • 16
    • 0035131701 scopus 로고    scopus 로고
    • A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
    • Gaiddon C, Lokshin M, Ahn J, Zhang T, Prives C. A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol Cell Biol 2001;21:1874-1887.
    • (2001) Mol Cell Biol , vol.21 , pp. 1874-1887
    • Gaiddon, C.1    Lokshin, M.2    Ahn, J.3    Zhang, T.4    Prives, C.5
  • 18
    • 0032951530 scopus 로고    scopus 로고
    • P73 function is inhibited by tumor-derived p53 mutants in mammalian cells
    • Di Como CJ, Gaiddon C, Prives C. p73 function is inhibited by tumor-derived p53 mutants in mammalian cells. Mol Cell Biol 1999;19:1438-1449.
    • (1999) Mol Cell Biol , vol.19 , pp. 1438-1449
    • Di Como, C.J.1    Gaiddon, C.2    Prives, C.3
  • 19
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009;136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 20
    • 84859632747 scopus 로고    scopus 로고
    • MiRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay
    • Djuranovic S, Nahvi A, Green R. miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay. Science 2012;336:237-240.
    • (2012) Science , vol.336 , pp. 237-240
    • Djuranovic, S.1    Nahvi, A.2    Green, R.3
  • 22
    • 69949098536 scopus 로고    scopus 로고
    • MIR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to 'seedless' 3'UTR microRNA recognition elements
    • Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E et al. miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to 'seedless' 3'UTR microRNA recognition elements. Mol Cell 2009;35:610-625.
    • (2009) Mol Cell , vol.35 , pp. 610-625
    • Lal, A.1    Navarro, F.2    Maher, C.A.3    Maliszewski, L.E.4    Yan, N.5    O'Day, E.6
  • 23
    • 84857955708 scopus 로고    scopus 로고
    • An alternative mode of microRNA target recognition
    • Chi SW, Hannon GJ, Darnell RB. An alternative mode of microRNA target recognition. Nat Struct Mol Biol 2012;19:321-327.
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 321-327
    • Chi, S.W.1    Hannon, G.J.2    Darnell, R.B.3
  • 24
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP, De Stanchina E, Xuan Z, Liang Y et al. A microRNA component of the p53 tumour suppressor network. Nature 2007;447:1130-1134.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    De Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 25
    • 52949091534 scopus 로고    scopus 로고
    • The let-7 family of microRNAs
    • Roush S, Slack FJ. The let-7 family of microRNAs. Trends Cell Biol 2008;18:505-516.
    • (2008) Trends Cell Biol , vol.18 , pp. 505-516
    • Roush, S.1    Slack, F.J.2
  • 26
    • 84866423871 scopus 로고    scopus 로고
    • MicroRNAs in the p53 network: Micromanagement of tumour suppression
    • Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer 2012;12:613-626.
    • (2012) Nat Rev Cancer , vol.12 , pp. 613-626
    • Hermeking, H.1
  • 27
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of MIR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 2007;26:745-752.
    • (2007) Mol Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 31
    • 73649145490 scopus 로고    scopus 로고
    • NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection
    • O'Hara SP, Splinter PL, Gajdos GB, Trussoni CE, Fernandez-Zapico ME, Chen XM et al. NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection. J Biol Chem 2010;285:216-225.
    • (2010) J Biol Chem , vol.285 , pp. 216-225
    • O'Hara, S.P.1    Splinter, P.L.2    Gajdos, G.B.3    Trussoni, C.E.4    Fernandez-Zapico, M.E.5    Chen, X.M.6
  • 32
    • 84859869155 scopus 로고    scopus 로고
    • Mutant p53 cooperates with ETS2 to promote etoposide resistance
    • Do PM, Varanasi L, Fan S, Li C, Kubacka I, Newman V et al. Mutant p53 cooperates with ETS2 to promote etoposide resistance. Genes Dev 2012;26:830-845.
    • (2012) Genes Dev , vol.26 , pp. 830-845
    • Do, P.M.1    Varanasi, L.2    Fan, S.3    Li, C.4    Kubacka, I.5    Newman, V.6
  • 34
    • 18544364361 scopus 로고    scopus 로고
    • Physical interaction with human tumor-derived p53 mutants inhibits p63 activities
    • Strano S, Fontemaggi G, Costanzo A, Rizzo MG, Monti O, Baccarini A et al. Physical interaction with human tumor-derived p53 mutants inhibits p63 activities. J Biol Chem 2002;277:18817-18826.
    • (2002) J Biol Chem , vol.277 , pp. 18817-18826
    • Strano, S.1    Fontemaggi, G.2    Costanzo, A.3    Rizzo, M.G.4    Monti, O.5    Baccarini, A.6
  • 36
    • 84872864743 scopus 로고    scopus 로고
    • On measuring miRNAs after transient transfection of mimics or antisense inhibitors
    • Thomson DW, Bracken CP, Szubert JM, Goodall GJ. On measuring miRNAs after transient transfection of mimics or antisense inhibitors. PLoS One 2013;8:e55214.
    • (2013) PLoS One , vol.8 , pp. e55214
    • Thomson, D.W.1    Bracken, C.P.2    Szubert, J.M.3    Goodall, G.J.4
  • 38
    • 33751042873 scopus 로고    scopus 로고
    • Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma
    • Guo Y, Chen Y, Ito H, Watanabe A, Ge X, Kodama T et al. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 2006;384:51-61.
    • (2006) Gene , vol.384 , pp. 51-61
    • Guo, Y.1    Chen, Y.2    Ito, H.3    Watanabe, A.4    Ge, X.5    Kodama, T.6
  • 39
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
    • Forman JJ, Legesse-Miller A, Coller HA. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci USA. 2008;105:14879-14884.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 41
    • 35449003175 scopus 로고    scopus 로고
    • MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
    • Sampson VB, Rong NH, Han J, Yang Q, Aris V, Soteropoulos P et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007;67:9762-9770.
    • (2007) Cancer Res , vol.67 , pp. 9762-9770
    • Sampson, V.B.1    Rong, N.H.2    Han, J.3    Yang, Q.4    Aris, V.5    Soteropoulos, P.6
  • 43
    • 0031834336 scopus 로고    scopus 로고
    • Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain
    • Frazier MW, He X, Wang J, Gu Z, Cleveland JL, Zambetti GP. Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain. Mol Cell Biol 1998;18:3735-3743.
    • (1998) Mol Cell Biol , vol.18 , pp. 3735-3743
    • Frazier, M.W.1    He, X.2    Wang, J.3    Gu, Z.4    Cleveland, J.L.5    Zambetti, G.P.6
  • 44
    • 80053585752 scopus 로고    scopus 로고
    • LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms
    • King CE, Wang L, Winograd R, Madison BB, Mongroo PS, Johnstone CN et al. LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms. Oncogene 2011;30:4185-4193.
    • (2011) Oncogene , vol.30 , pp. 4185-4193
    • King, C.E.1    Wang, L.2    Winograd, R.3    Madison, B.B.4    Mongroo, P.S.5    Johnstone, C.N.6
  • 45
    • 79952770168 scopus 로고    scopus 로고
    • MYC and metastasis
    • Wolfer A, Ramaswamy S. MYC and metastasis. Cancer Res 2011;71:2034-2037.
    • (2011) Cancer Res , vol.71 , pp. 2034-2037
    • Wolfer, A.1    Ramaswamy, S.2
  • 46
    • 84860745157 scopus 로고    scopus 로고
    • MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function
    • Donzelli S, Fontemaggi G, Fazi F, Di Agostino S, Padula F, Biagioni F et al. MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function. Cell Death Differ 2011;19:1038-1048.
    • (2011) Cell Death Differ , vol.19 , pp. 1038-1048
    • Donzelli, S.1    Fontemaggi, G.2    Fazi, F.3    Di Agostino, S.4    Padula, F.5    Biagioni, F.6
  • 47
    • 84879736644 scopus 로고    scopus 로고
    • Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing MIR-27a expression
    • Wang W, Cheng B, Miao L, Mei Y, Wu M. Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression. Cell Death Dis 2013;4:e574.
    • (2013) Cell Death Dis , vol.4 , pp. e574
    • Wang, W.1    Cheng, B.2    Miao, L.3    Mei, Y.4    Wu, M.5
  • 48
    • 84880298880 scopus 로고    scopus 로고
    • Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the MIR-130b-ZEB1 axis
    • Dong P, Karaayvaz M, Jia N, Kaneuchi M, Hamada J, Watari H et al. Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis. Oncogene 2012;32:3286-3295.
    • (2012) Oncogene , vol.32 , pp. 3286-3295
    • Dong, P.1    Karaayvaz, M.2    Jia, N.3    Kaneuchi, M.4    Hamada, J.5    Watari, H.6
  • 53
    • 79961016545 scopus 로고    scopus 로고
    • Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML
    • Payne EM, Bolli N, Rhodes J, Abdel-Wahab OI, Levine R, Hedvat CV et al. Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML. Blood 2011;118:903-915.
    • (2011) Blood , vol.118 , pp. 903-915
    • Payne, E.M.1    Bolli, N.2    Rhodes, J.3    Abdel-Wahab, O.I.4    Levine, R.5    Hedvat, C.V.6
  • 54
    • 84862776516 scopus 로고    scopus 로고
    • High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer
    • Hamano R, Miyata H, Yamasaki M, Sugimura K, Tanaka K, Kurokawa Y et al. High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer. Br J Cancer 2012;106:1415-1423.
    • (2012) Br J Cancer , vol.106 , pp. 1415-1423
    • Hamano, R.1    Miyata, H.2    Yamasaki, M.3    Sugimura, K.4    Tanaka, K.5    Kurokawa, Y.6
  • 55
    • 81755163085 scopus 로고    scopus 로고
    • Capture of microRNA-bound mRNAs identifies the tumor suppressor MIR-34a as a regulator of growth factor signaling
    • Lal A, Thomas MP, Altschuler G, Navarro F, O'Day E, Li XL et al. Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling. PLoS Genet 2011;7:e1002363.
    • (2011) PLoS Genet , vol.7 , pp. e1002363
    • Lal, A.1    Thomas, M.P.2    Altschuler, G.3    Navarro, F.4    O'Day, E.5    Li, X.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.