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Volumn 50, Issue 5, 2014, Pages 339-344

DNA damage checkpoints in nasopharyngeal carcinoma

Author keywords

Cell cycle; Checkpoints; DNA damage responses; Epstein Barr virus; NPC

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN D; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; PROTEIN P16; PROTEIN P21; PROTEIN P53; CELL CYCLE PROTEIN;

EID: 84899104417     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2014.01.009     Document Type: Article
Times cited : (17)

References (81)
  • 2
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • N. Raab-Traub Epstein-Barr virus in the pathogenesis of NPC Semin Cancer Biol 12 6 2002 431 441
    • (2002) Semin Cancer Biol , vol.12 , Issue.6 , pp. 431-441
    • Raab-Traub, N.1
  • 3
    • 33750532057 scopus 로고    scopus 로고
    • The enigmatic epidemiology of nasopharyngeal carcinoma
    • E.T. Chang, and H.O. Adami The enigmatic epidemiology of nasopharyngeal carcinoma Cancer Epidemiol Biomark Prev 15 10 2006 1765 1777
    • (2006) Cancer Epidemiol Biomark Prev , vol.15 , Issue.10 , pp. 1765-1777
    • Chang, E.T.1    Adami, H.O.2
  • 4
    • 66549123370 scopus 로고    scopus 로고
    • Nasopharyngeal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
    • A.T. Chan, and E. Felip Nasopharyngeal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up Ann Oncol 20 Suppl. 4 2009 4123 4125
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 4 , pp. 4123-4125
    • Chan, A.T.1    Felip, E.2
  • 5
    • 0026720425 scopus 로고
    • Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985: Overall survival and patterns of failure
    • A.W. Lee, Y.F. Poon, W. Foo, S.C. Law, F.K. Cheung, and D.K. Chan et al. Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985: overall survival and patterns of failure Int J Radiat Oncol Biol Phys 23 2 1992 261 270
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , Issue.2 , pp. 261-270
    • Lee, A.W.1    Poon, Y.F.2    Foo, W.3    Law, S.C.4    Cheung, F.K.5    Chan, D.K.6
  • 6
    • 0142068802 scopus 로고    scopus 로고
    • Cyclin-dependent kinases and S phase control in mammalian cells
    • R.A. Woo, and R.Y. Poon Cyclin-dependent kinases and S phase control in mammalian cells Cell Cycle 2 4 2003 316 324
    • (2003) Cell Cycle , vol.2 , Issue.4 , pp. 316-324
    • Woo, R.A.1    Poon, R.Y.2
  • 7
    • 3242887431 scopus 로고    scopus 로고
    • Dial 9-1-1 for DNA damage: The Rad9-Hus1-Rad1 (9-1-1) clamp complex
    • E.R. Parrilla-Castellar, S.J. Arlander, and L. Karnitz Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex DNA Repair (Amst) 3 8-9 2004 1009 1014
    • (2004) DNA Repair (Amst) , vol.3 , Issue.89 , pp. 1009-1014
    • Parrilla-Castellar, E.R.1    Arlander, S.J.2    Karnitz, L.3
  • 8
    • 3142670793 scopus 로고    scopus 로고
    • BRCA1 in cancer, cell cycle and genomic stability
    • M. Jhanwar-Uniyal BRCA1 in cancer, cell cycle and genomic stability Front Biosci 8 2003 S1107 S1117
    • (2003) Front Biosci , vol.8
    • Jhanwar-Uniyal, M.1
  • 9
    • 0034655991 scopus 로고    scopus 로고
    • BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
    • Y. Wang, D. Cortez, P. Yazdi, N. Neff, S.J. Elledge, and J. Qin BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures Genes Dev 14 8 2000 927 939
    • (2000) Genes Dev , vol.14 , Issue.8 , pp. 927-939
    • Wang, Y.1    Cortez, D.2    Yazdi, P.3    Neff, N.4    Elledge, S.J.5    Qin, J.6
  • 10
    • 47749141560 scopus 로고    scopus 로고
    • ATR: An essential regulator of genome integrity
    • K.A. Cimprich, and D. Cortez ATR: an essential regulator of genome integrity Nat Rev Mol Cell Biol 9 8 2008 616 627
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.8 , pp. 616-627
    • Cimprich, K.A.1    Cortez, D.2
  • 11
    • 33749599776 scopus 로고    scopus 로고
    • Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase
    • E. Petermann, and K.W. Caldecott Evidence that the ATR/Chk1 pathway maintains normal replication fork progression during unperturbed S phase Cell Cycle 5 19 2006 2203 2209
    • (2006) Cell Cycle , vol.5 , Issue.19 , pp. 2203-2209
    • Petermann, E.1    Caldecott, K.W.2
  • 12
    • 33845658109 scopus 로고    scopus 로고
    • Claspin: Timing the cell cycle arrest when the genome is damaged
    • R. Freire, M.A. van Vugt, I. Mamely, and R.H. Medema Claspin: timing the cell cycle arrest when the genome is damaged Cell Cycle 5 24 2006 2831 2834
    • (2006) Cell Cycle , vol.5 , Issue.24 , pp. 2831-2834
    • Freire, R.1    Van Vugt, M.A.2    Mamely, I.3    Medema, R.H.4
  • 14
    • 33644856152 scopus 로고    scopus 로고
    • The when and wheres of CDC25 phosphatases
    • R. Boutros, C. Dozier, and B. Ducommun The when and wheres of CDC25 phosphatases Curr Opin Cell Biol 18 2 2006 185 191
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.2 , pp. 185-191
    • Boutros, R.1    Dozier, C.2    Ducommun, B.3
  • 15
    • 42649131088 scopus 로고    scopus 로고
    • The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability
    • Y. Chen, and R.Y. Poon The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability Front Biosci 2008 135016 135029
    • (2008) Front Biosci , pp. 135016-135029
    • Chen, Y.1    Poon, R.Y.2
  • 16
    • 4444345565 scopus 로고    scopus 로고
    • Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
    • A. Kramer, N. Mailand, C. Lukas, R.G. Syljuasen, C.J. Wilkinson, and E.A. Nigg et al. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase Nat Cell Biol 6 9 2004 884 891
    • (2004) Nat Cell Biol , vol.6 , Issue.9 , pp. 884-891
    • Kramer, A.1    Mailand, N.2    Lukas, C.3    Syljuasen, R.G.4    Wilkinson, C.J.5    Nigg, E.A.6
  • 17
    • 70349652574 scopus 로고    scopus 로고
    • NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint
    • M. Melixetian, D.K. Klein, C.S. Sorensen, and K. Helin NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint Nat Cell Biol 11 10 2009 1247 1253
    • (2009) Nat Cell Biol , vol.11 , Issue.10 , pp. 1247-1253
    • Melixetian, M.1    Klein, D.K.2    Sorensen, C.S.3    Helin, K.4
  • 18
    • 77953479905 scopus 로고    scopus 로고
    • Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction
    • Y. Honaker, and H. Piwnica-Worms Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction Oncogene 29 23 2010 3324 3334
    • (2010) Oncogene , vol.29 , Issue.23 , pp. 3324-3334
    • Honaker, Y.1    Piwnica-Worms, H.2
  • 19
    • 0035158899 scopus 로고    scopus 로고
    • Positive regulation of Wee1 by Chk1 and 14-3-3 proteins
    • J. Lee, A. Kumagai, and W.G. Dunphy Positive regulation of Wee1 by Chk1 and 14-3-3 proteins Mol Biol Cell 12 3 2001 551 563
    • (2001) Mol Biol Cell , vol.12 , Issue.3 , pp. 551-563
    • Lee, J.1    Kumagai, A.2    Dunphy, W.G.3
  • 20
    • 0035704094 scopus 로고    scopus 로고
    • 14-3-3 Binding regulates catalytic activity of human Wee1 kinase
    • C.J. Rothblum-Oviatt, C.E. Ryan, and H. Piwnica-Worms 14-3-3 Binding regulates catalytic activity of human Wee1 kinase Cell Growth Differ 12 12 2001 581 589
    • (2001) Cell Growth Differ , vol.12 , Issue.12 , pp. 581-589
    • Rothblum-Oviatt, C.J.1    Ryan, C.E.2    Piwnica-Worms, H.3
  • 21
    • 0033533612 scopus 로고    scopus 로고
    • 14-3-3 Sigma is required to prevent mitotic catastrophe after DNA damage
    • T.A. Chan, H. Hermeking, C. Lengauer, K.W. Kinzler, and B. Vogelstein 14-3-3 Sigma is required to prevent mitotic catastrophe after DNA damage Nature 401 6753 1999 616 620
    • (1999) Nature , vol.401 , Issue.6753 , pp. 616-620
    • Chan, T.A.1    Hermeking, H.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 22
    • 0030442814 scopus 로고    scopus 로고
    • Mammalian X ray sensitive mutants: A tool for the elucidation of the cellular response to ionizing radiation
    • M.Z. Zdzienicka Mammalian X ray sensitive mutants: a tool for the elucidation of the cellular response to ionizing radiation Cancer Surv 1996 28281 28293
    • (1996) Cancer Surv , pp. 28281-28293
    • Zdzienicka, M.Z.1
  • 23
    • 0034649641 scopus 로고    scopus 로고
    • Checkpoints: It takes more than time to heal some wounds
    • R908-11
    • N. Rhind, and P. Russell Checkpoints: it takes more than time to heal some wounds Curr Biol 10 24 2000 R908-11
    • (2000) Curr Biol , vol.10 , Issue.24
    • Rhind, N.1    Russell, P.2
  • 24
    • 0036510055 scopus 로고    scopus 로고
    • The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
    • J. Falck, J.H. Petrini, B.R. Williams, J. Lukas, and J. Bartek The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways Nat Genet 30 3 2002 290 294
    • (2002) Nat Genet , vol.30 , Issue.3 , pp. 290-294
    • Falck, J.1    Petrini, J.H.2    Williams, B.R.3    Lukas, J.4    Bartek, J.5
  • 25
    • 33646807832 scopus 로고    scopus 로고
    • The P53 pathway: What questions remain to be explored?
    • A.J. Levine, W. Hu, and Z. Feng The P53 pathway: what questions remain to be explored? Cell Death Differ 13 6 2006 1027 1036
    • (2006) Cell Death Differ , vol.13 , Issue.6 , pp. 1027-1036
    • Levine, A.J.1    Hu, W.2    Feng, Z.3
  • 26
    • 0033598754 scopus 로고    scopus 로고
    • Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
    • N.H. Chehab, A. Malikzay, E.S. Stavridi, and T.D. Halazonetis Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage Proc Natl Acad Sci USA 96 24 1999 13777 13782
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.24 , pp. 13777-13782
    • Chehab, N.H.1    Malikzay, A.2    Stavridi, E.S.3    Halazonetis, T.D.4
  • 27
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • S.Y. Shieh, M. Ikeda, Y. Taya, and C. Prives DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 Cell 91 3 1997 325 334
    • (1997) Cell , vol.91 , Issue.3 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 28
    • 0034142325 scopus 로고    scopus 로고
    • Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
    • N.H. Chehab, A. Malikzay, M. Appel, and T.D. Halazonetis Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53 Genes Dev 14 3 2000 278 288
    • (2000) Genes Dev , vol.14 , Issue.3 , pp. 278-288
    • Chehab, N.H.1    Malikzay, A.2    Appel, M.3    Halazonetis, T.D.4
  • 29
    • 0034629072 scopus 로고    scopus 로고
    • DNA damage-induced activation of p53 by the checkpoint kinase Chk2
    • A. Hirao, Y.Y. Kong, S. Matsuoka, A. Wakeham, J. Ruland, and H. Yoshida et al. DNA damage-induced activation of p53 by the checkpoint kinase Chk2 Science 287 5459 2000 1824 1827
    • (2000) Science , vol.287 , Issue.5459 , pp. 1824-1827
    • Hirao, A.1    Kong, Y.Y.2    Matsuoka, S.3    Wakeham, A.4    Ruland, J.5    Yoshida, H.6
  • 30
    • 0034142034 scopus 로고    scopus 로고
    • The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
    • S.Y. Shieh, J. Ahn, K. Tamai, Y. Taya, and C. Prives The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites Genes Dev 14 3 2000 289 300
    • (2000) Genes Dev , vol.14 , Issue.3 , pp. 289-300
    • Shieh, S.Y.1    Ahn, J.2    Tamai, K.3    Taya, Y.4    Prives, C.5
  • 31
    • 0032553485 scopus 로고    scopus 로고
    • Requirement for p53 and p21 to sustain G2 arrest after DNA damage
    • F. Bunz, A. Dutriaux, C. Lengauer, T. Waldman, S. Zhou, and J.P. Brown et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage Science 282 5393 1998 1497 1501
    • (1998) Science , vol.282 , Issue.5393 , pp. 1497-1501
    • Bunz, F.1    Dutriaux, A.2    Lengauer, C.3    Waldman, T.4    Zhou, S.5    Brown, J.P.6
  • 32
    • 65249099623 scopus 로고    scopus 로고
    • DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest
    • J. Lee, J.A. Kim, V. Barbier, A. Fotedar, and R. Fotedar DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest Mol Biol Cell 20 7 2009 1891 1902
    • (2009) Mol Biol Cell , vol.20 , Issue.7 , pp. 1891-1902
    • Lee, J.1    Kim, J.A.2    Barbier, V.3    Fotedar, A.4    Fotedar, R.5
  • 33
    • 84882433672 scopus 로고    scopus 로고
    • Interplay between DNA tumor viruses and the host DNA damage response
    • K. McFadden, and M.A. Luftig Interplay between DNA tumor viruses and the host DNA damage response Curr Top Microbiol Immunol 2013 371229 371257
    • (2013) Curr Top Microbiol Immunol , pp. 371229-371257
    • McFadden, K.1    Luftig, M.A.2
  • 34
    • 78650217703 scopus 로고    scopus 로고
    • An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells
    • P.A. Nikitin, C.M. Yan, E. Forte, A. Bocedi, J.P. Tourigny, and R.E. White et al. An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells Cell Host Microbe 8 6 2010 510 522
    • (2010) Cell Host Microbe , vol.8 , Issue.6 , pp. 510-522
    • Nikitin, P.A.1    Yan, C.M.2    Forte, E.3    Bocedi, A.4    Tourigny, J.P.5    White, R.E.6
  • 35
    • 60549116871 scopus 로고    scopus 로고
    • The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma
    • S. Bose, L.F. Yap, M. Fung, J. Starzcynski, A. Saleh, and S. Morgan et al. The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma J Pathol 217 3 2009 345 352
    • (2009) J Pathol , vol.217 , Issue.3 , pp. 345-352
    • Bose, S.1    Yap, L.F.2    Fung, M.3    Starzcynski, J.4    Saleh, A.5    Morgan, S.6
  • 36
    • 43449138197 scopus 로고    scopus 로고
    • A role for MRE11, NBS1, and recombination junctions in replication and stable maintenance of EBV episomes
    • J. Dheekollu, Z. Deng, A. Wiedmer, M.D. Weitzman, and P.M. Lieberman A role for MRE11, NBS1, and recombination junctions in replication and stable maintenance of EBV episomes PLoS ONE 2 12 2007 e1257
    • (2007) PLoS ONE , vol.2 , Issue.12 , pp. 1257
    • Dheekollu, J.1    Deng, Z.2    Wiedmer, A.3    Weitzman, M.D.4    Lieberman, P.M.5
  • 37
    • 77951463648 scopus 로고    scopus 로고
    • Regulation of Epstein-Barr virus origin of plasmid replication (OriP) by the S-phase checkpoint kinase Chk2
    • J. Zhou, Z. Deng, J. Norseen, and P.M. Lieberman Regulation of Epstein-Barr virus origin of plasmid replication (OriP) by the S-phase checkpoint kinase Chk2 J Virol 84 10 2010 4979 4987
    • (2010) J Virol , vol.84 , Issue.10 , pp. 4979-4987
    • Zhou, J.1    Deng, Z.2    Norseen, J.3    Lieberman, P.M.4
  • 38
    • 34249947000 scopus 로고    scopus 로고
    • The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block
    • T. Choudhuri, S.C. Verma, K. Lan, M. Murakami, and E.S. Robertson The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block J Virol 81 12 2007 6718 6730
    • (2007) J Virol , vol.81 , Issue.12 , pp. 6718-6730
    • Choudhuri, T.1    Verma, S.C.2    Lan, K.3    Murakami, M.4    Robertson, E.S.5
  • 39
    • 84862666553 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activation
    • W. Deng, P.S. Pang, C.M. Tsang, P.M. Hau, Y.L. Yip, and A.L. Cheung et al. Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activation PLoS ONE 7 6 2012 e39095
    • (2012) PLoS ONE , vol.7 , Issue.6 , pp. 39095
    • Deng, W.1    Pang, P.S.2    Tsang, C.M.3    Hau, P.M.4    Yip, Y.L.5    Cheung, A.L.6
  • 40
    • 62549160416 scopus 로고    scopus 로고
    • MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma
    • H.C. Chen, G.H. Chen, Y.H. Chen, W.L. Liao, C.Y. Liu, and K.P. Chang et al. MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma Br J Cancer 100 6 2009 1002 1011
    • (2009) Br J Cancer , vol.100 , Issue.6 , pp. 1002-1011
    • Chen, H.C.1    Chen, G.H.2    Chen, Y.H.3    Liao, W.L.4    Liu, C.Y.5    Chang, K.P.6
  • 41
    • 77949904204 scopus 로고    scopus 로고
    • Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer
    • W. Shi, N.M. Alajez, C. Bastianutto, A.B. Hui, J.D. Mocanu, and E. Ito et al. Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer Int J Cancer 126 9 2010 2036 2048
    • (2010) Int J Cancer , vol.126 , Issue.9 , pp. 2036-2048
    • Shi, W.1    Alajez, N.M.2    Bastianutto, C.3    Hui, A.B.4    Mocanu, J.D.5    Ito, E.6
  • 42
    • 14844336913 scopus 로고    scopus 로고
    • Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment
    • A. Kudoh, M. Fujita, L. Zhang, N. Shirata, T. Daikoku, and Y. Sugaya et al. Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment J Biol Chem 280 9 2005 8156 8163
    • (2005) J Biol Chem , vol.280 , Issue.9 , pp. 8156-8163
    • Kudoh, A.1    Fujita, M.2    Zhang, L.3    Shirata, N.4    Daikoku, T.5    Sugaya, Y.6
  • 43
    • 84870704593 scopus 로고    scopus 로고
    • The cellular ataxia telangiectasia-mutated kinase promotes Epstein-Barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli
    • S.R. Hagemeier, E.A. Barlow, Q. Meng, and S.C. Kenney The cellular ataxia telangiectasia-mutated kinase promotes Epstein-Barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli J Virol 86 24 2012 13360 13370
    • (2012) J Virol , vol.86 , Issue.24 , pp. 13360-13370
    • Hagemeier, S.R.1    Barlow, E.A.2    Meng, Q.3    Kenney, S.C.4
  • 44
    • 80054896036 scopus 로고    scopus 로고
    • Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication
    • R. Li, J. Zhu, Z. Xie, G. Liao, J. Liu, and M.R. Chen et al. Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication Cell Host Microbe 10 4 2011 390 400
    • (2011) Cell Host Microbe , vol.10 , Issue.4 , pp. 390-400
    • Li, R.1    Zhu, J.2    Xie, Z.3    Liao, G.4    Liu, J.5    Chen, M.R.6
  • 45
    • 70450202262 scopus 로고    scopus 로고
    • Overexpression of cyclin e messenger ribonucleic acid in nasopharyngeal carcinoma correlates with poor prognosis
    • M.T. Ko, C.Y. Su, S.C. Huang, C.H. Chen, and C.F. Hwang Overexpression of cyclin E messenger ribonucleic acid in nasopharyngeal carcinoma correlates with poor prognosis J Laryngol Otol 123 9 2009 1021 1026
    • (2009) J Laryngol Otol , vol.123 , Issue.9 , pp. 1021-1026
    • Ko, M.T.1    Su, C.Y.2    Huang, S.C.3    Chen, C.H.4    Hwang, C.F.5
  • 46
    • 78651411120 scopus 로고    scopus 로고
    • MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2
    • J. Lu, M.L. He, L. Wang, Y. Chen, X. Liu, and Q. Dong et al. MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2 Cancer Res 71 1 2011 225 233
    • (2011) Cancer Res , vol.71 , Issue.1 , pp. 225-233
    • Lu, J.1    He, M.L.2    Wang, L.3    Chen, Y.4    Liu, X.5    Dong, Q.6
  • 48
    • 84862908939 scopus 로고    scopus 로고
    • Integrated analysis of multiple gene expression profiling datasets revealed novel gene signatures and molecular markers in nasopharyngeal carcinoma
    • C. Huang, H. Tang, W. Zhang, X. She, Q. Liao, and X. Li et al. Integrated analysis of multiple gene expression profiling datasets revealed novel gene signatures and molecular markers in nasopharyngeal carcinoma Cancer Epidemiol Biomar Prev 21 1 2012 166 175
    • (2012) Cancer Epidemiol Biomar Prev , vol.21 , Issue.1 , pp. 166-175
    • Huang, C.1    Tang, H.2    Zhang, W.3    She, X.4    Liao, Q.5    Li, X.6
  • 49
    • 84863787468 scopus 로고    scopus 로고
    • MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene
    • X. Liu, X.B. Lv, X.P. Wang, Y. Sang, S. Xu, and K. Hu et al. MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene Cell Cycle 11 13 2012 2495 2506
    • (2012) Cell Cycle , vol.11 , Issue.13 , pp. 2495-2506
    • Liu, X.1    Lv, X.B.2    Wang, X.P.3    Sang, Y.4    Xu, S.5    Hu, K.6
  • 50
    • 84897887113 scopus 로고    scopus 로고
    • Nuclear expression of CDK4 correlates with disease progression and poor prognosis in human nasopharyngeal carcinoma
    • Q. Jiang, C. Mai, H. Yang, Q. Wu, S. Hua, and Y. Chen et al. Nuclear expression of CDK4 correlates with disease progression and poor prognosis in human nasopharyngeal carcinoma Histopathol 2013
    • (2013) Histopathol
    • Jiang, Q.1    Mai, C.2    Yang, H.3    Wu, Q.4    Hua, S.5    Chen, Y.6
  • 51
    • 0036668666 scopus 로고    scopus 로고
    • Loss of cyclin D1 and p16 expression correlates with local recurrence in nasopharyngeal carcinoma following radiotherapy
    • C.F. Hwang, C.L. Cho, C.C. Huang, J.S. Wang, Y.L. Shih, and C.Y. Su et al. Loss of cyclin D1 and p16 expression correlates with local recurrence in nasopharyngeal carcinoma following radiotherapy Ann Oncol 13 8 2002 1246 1251
    • (2002) Ann Oncol , vol.13 , Issue.8 , pp. 1246-1251
    • Hwang, C.F.1    Cho, C.L.2    Huang, C.C.3    Wang, J.S.4    Shih, Y.L.5    Su, C.Y.6
  • 52
    • 0032759897 scopus 로고    scopus 로고
    • Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinoma
    • G.L. Wang, K.W. Lo, K.S. Tsang, N.Y. Chung, Y.S. Tsang, and S.T. Cheung et al. Inhibiting tumorigenic potential by restoration of p16 in nasopharyngeal carcinoma Br J Cancer 81 7 1999 1122 1126
    • (1999) Br J Cancer , vol.81 , Issue.7 , pp. 1122-1126
    • Wang, G.L.1    Lo, K.W.2    Tsang, K.S.3    Chung, N.Y.4    Tsang, Y.S.5    Cheung, S.T.6
  • 53
    • 0037838642 scopus 로고    scopus 로고
    • Loss of p16 expression has prognostic significance in human nasopharyngeal carcinoma
    • A.A. Makitie, C. MacMillan, J. Ho, W. Shi, A. Lee, and B. O'Sullivan et al. Loss of p16 expression has prognostic significance in human nasopharyngeal carcinoma Clin Cancer Res 9 6 2003 2177 2184
    • (2003) Clin Cancer Res , vol.9 , Issue.6 , pp. 2177-2184
    • Makitie, A.A.1    Macmillan, C.2    Ho, J.3    Shi, W.4    Lee, A.5    O'Sullivan, B.6
  • 54
    • 2442466567 scopus 로고    scopus 로고
    • P16 gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma
    • A.W. Lee, J.H. Li, W. Shi, A. Li, E. Ng, and T.J. Liu et al. P16 gene therapy: a potentially efficacious modality for nasopharyngeal carcinoma Mol Cancer Ther 2 10 2003 961 969
    • (2003) Mol Cancer Ther , vol.2 , Issue.10 , pp. 961-969
    • Lee, A.W.1    Li, J.H.2    Shi, W.3    Li, A.4    Ng, E.5    Liu, T.J.6
  • 56
    • 84865346500 scopus 로고    scopus 로고
    • Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1
    • Y. Shi, Y. Tao, Y. Jiang, Y. Xu, B. Yan, and X. Chen et al. Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1 Carcinogenesis 33 8 2012 1468 1478
    • (2012) Carcinogenesis , vol.33 , Issue.8 , pp. 1468-1478
    • Shi, Y.1    Tao, Y.2    Jiang, Y.3    Xu, Y.4    Yan, B.5    Chen, X.6
  • 58
    • 79952209417 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1
    • A. Saha, S. Halder, S.K. Upadhyay, J. Lu, P. Kumar, and M. Murakami et al. Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1 PLoS Pathog 7 2 2011 e1001275
    • (2011) PLoS Pathog , vol.7 , Issue.2 , pp. 1001275
    • Saha, A.1    Halder, S.2    Upadhyay, S.K.3    Lu, J.4    Kumar, P.5    Murakami, M.6
  • 60
    • 77954664053 scopus 로고    scopus 로고
    • INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP
    • INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP PLoS Pathog 6 6 2010 e1000951
    • (2010) PLoS Pathog , vol.6 , Issue.6 , pp. 1000951
    • Skalska, L.1    White, R.E.2    Franz, M.3    Ruhmann, M.4    Allday, M.J.5
  • 61
    • 29444438631 scopus 로고    scopus 로고
    • Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase
    • J.S. Knight, N. Sharma, and E.S. Robertson Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase Proc Natl Acad Sci USA 102 51 2005 18562 18566
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.51 , pp. 18562-18566
    • Knight, J.S.1    Sharma, N.2    Robertson, E.S.3
  • 62
    • 0042168998 scopus 로고    scopus 로고
    • The latent membrane protein 1 of Epstein-Barr virus and loss of the INK4a locus: Paradoxes resolve to cooperation in carcinogenesis in vivo
    • J. Macdiarmid, D. Stevenson, D.H. Campbell, and J.B. Wilson The latent membrane protein 1 of Epstein-Barr virus and loss of the INK4a locus: paradoxes resolve to cooperation in carcinogenesis in vivo Carcinogenesis 24 7 2003 1209 1218
    • (2003) Carcinogenesis , vol.24 , Issue.7 , pp. 1209-1218
    • Macdiarmid, J.1    Stevenson, D.2    Campbell, D.H.3    Wilson, J.B.4
  • 63
    • 84870931320 scopus 로고    scopus 로고
    • Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells
    • C.M. Tsang, Y.L. Yip, K.W. Lo, W. Deng, K.F. To, and P.M. Hau et al. Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells Proc Natl Acad Sci USA 109 50 2012 E3473 E3482
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.50
    • Tsang, C.M.1    Yip, Y.L.2    Lo, K.W.3    Deng, W.4    To, K.F.5    Hau, P.M.6
  • 64
  • 65
    • 16244408015 scopus 로고    scopus 로고
    • Expression of p53 protein and primary tumour volume in patients with nasopharyngeal carcinoma
    • M.K. Chen, H.S. Lee, J.H. Chang, and C.C. Chang Expression of p53 protein and primary tumour volume in patients with nasopharyngeal carcinoma J Otolaryngol 33 5 2004 304 307
    • (2004) J Otolaryngol , vol.33 , Issue.5 , pp. 304-307
    • Chen, M.K.1    Lee, H.S.2    Chang, J.H.3    Chang, C.C.4
  • 66
    • 0036152306 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma
    • J. Kwong, K.W. Lo, K.F. To, P.M. Teo, P.J. Johnson, and D.P. Huang Promoter hypermethylation of multiple genes in nasopharyngeal carcinoma Clin Cancer Res 8 1 2002 131 137
    • (2002) Clin Cancer Res , vol.8 , Issue.1 , pp. 131-137
    • Kwong, J.1    Lo, K.W.2    To, K.F.3    Teo, P.M.4    Johnson, P.J.5    Huang, D.P.6
  • 67
    • 67649445782 scopus 로고    scopus 로고
    • Functional characterization of p53 in nasopharyngeal carcinoma by stable shRNA expression
    • Y. Sun, H. Yi, Y. Yang, Y. Yu, Y. Ouyang, and F. Yang et al. Functional characterization of p53 in nasopharyngeal carcinoma by stable shRNA expression Int J Oncol 34 4 2009 1017 1027
    • (2009) Int J Oncol , vol.34 , Issue.4 , pp. 1017-1027
    • Sun, Y.1    Yi, H.2    Yang, Y.3    Yu, Y.4    Ouyang, Y.5    Yang, F.6
  • 68
    • 0034644195 scopus 로고    scopus 로고
    • High level expression of deltaN-p63: A mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?
    • T. Crook, J.M. Nicholls, L. Brooks, J. O'Nions, and M.J. Allday High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)? Oncogene 19 30 2000 3439 3444
    • (2000) Oncogene , vol.19 , Issue.30 , pp. 3439-3444
    • Crook, T.1    Nicholls, J.M.2    Brooks, L.3    O'Nions, J.4    Allday, M.J.5
  • 69
    • 65349143744 scopus 로고    scopus 로고
    • Inactivation of 14-3-3 sigma by promoter methylation correlates with metastasis in nasopharyngeal carcinoma
    • B. Yi, S.X. Tan, C.E. Tang, W.G. Huang, A.L. Cheng, and C. Li et al. Inactivation of 14-3-3 sigma by promoter methylation correlates with metastasis in nasopharyngeal carcinoma J Cell Biochem 106 5 2009 858 866
    • (2009) J Cell Biochem , vol.106 , Issue.5 , pp. 858-866
    • Yi, B.1    Tan, S.X.2    Tang, C.E.3    Huang, W.G.4    Cheng, A.L.5    Li, C.6
  • 70
    • 84867397321 scopus 로고    scopus 로고
    • MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma
    • C. Yi, Q. Wang, L. Wang, Y. Huang, L. Li, and L. Liu et al. MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma Oncogene 31 41 2012 4421 4433
    • (2012) Oncogene , vol.31 , Issue.41 , pp. 4421-4433
    • Yi, C.1    Wang, Q.2    Wang, L.3    Huang, Y.4    Li, L.5    Liu, L.6
  • 71
    • 0029145975 scopus 로고
    • Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
    • R.Y.C. Poon, H. Toyoshima, and T. Hunter Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation Mol Biol Cell 6 9 1995 1197 1213
    • (1995) Mol Biol Cell , vol.6 , Issue.9 , pp. 1197-1213
    • Poon, R.Y.C.1    Toyoshima, H.2    Hunter, T.3
  • 73
    • 84859387866 scopus 로고    scopus 로고
    • Jab1/CSN5 negatively regulates p27 and plays a role in the pathogenesis of nasopharyngeal carcinoma
    • Y. Pan, Q. Zhang, L. Tian, X. Wang, X. Fan, and H. Zhang et al. Jab1/CSN5 negatively regulates p27 and plays a role in the pathogenesis of nasopharyngeal carcinoma Cancer Res 72 7 2012 1890 1900
    • (2012) Cancer Res , vol.72 , Issue.7 , pp. 1890-1900
    • Pan, Y.1    Zhang, Q.2    Tian, L.3    Wang, X.4    Fan, X.5    Zhang, H.6
  • 74
    • 66149106996 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2
    • A. Saha, M. Murakami, P. Kumar, B. Bajaj, K. Sims, and E.S. Robertson Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2 J Virol 83 9 2009 4652 4669
    • (2009) J Virol , vol.83 , Issue.9 , pp. 4652-4669
    • Saha, A.1    Murakami, M.2    Kumar, P.3    Bajaj, B.4    Sims, K.5    Robertson, E.S.6
  • 75
    • 67349118372 scopus 로고    scopus 로고
    • Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities
    • F. Yi, A. Saha, M. Murakami, P. Kumar, J.S. Knight, and Q. Cai et al. Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities Virology 388 2 2009 236 247
    • (2009) Virology , vol.388 , Issue.2 , pp. 236-247
    • Yi, F.1    Saha, A.2    Murakami, M.3    Kumar, P.4    Knight, J.S.5    Cai, Q.6
  • 76
    • 14044257866 scopus 로고    scopus 로고
    • Skp2 complex targeted by Epstein-Barr virus essential nuclear antigen
    • Skp2 complex targeted by Epstein-Barr virus essential nuclear antigen Mol Cell Biol 25 5 2005 1749 1763
    • (2005) Mol Cell Biol , vol.25 , Issue.5 , pp. 1749-1763
    • Knight, J.S.1    Sharma, N.2    Robertson, E.S.3
  • 77
    • 10044262203 scopus 로고    scopus 로고
    • MDM2 expression in EBV-infected nasopharyngeal carcinoma cells
    • H.C. Wu, T.Y. Lu, J.J. Lee, J.K. Hwang, Y.J. Lin, and C.K. Wang et al. MDM2 expression in EBV-infected nasopharyngeal carcinoma cells Lab Invest 84 12 2004 1547 1556
    • (2004) Lab Invest , vol.84 , Issue.12 , pp. 1547-1556
    • Wu, H.C.1    Lu, T.Y.2    Lee, J.J.3    Hwang, J.K.4    Lin, Y.J.5    Wang, C.K.6
  • 78
    • 77950519653 scopus 로고    scopus 로고
    • A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases
    • S. Gastaldello, S. Hildebrand, O. Faridani, S. Callegari, M. Palmkvist, and C. Di Guglielmo et al. A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases Nat Cell Biol 12 4 2010 351 361
    • (2010) Nat Cell Biol , vol.12 , Issue.4 , pp. 351-361
    • Gastaldello, S.1    Hildebrand, S.2    Faridani, O.3    Callegari, S.4    Palmkvist, M.5    Di Guglielmo, C.6
  • 79
    • 77956405785 scopus 로고    scopus 로고
    • Chk1 inhibitor Go6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo
    • Z. Feng, S. Xu, M. Liu, Y.X. Zeng, and T. Kang Chk1 inhibitor Go6976 enhances the sensitivity of nasopharyngeal carcinoma cells to radiotherapy and chemotherapy in vitro and in vivo Cancer Lett 297 2 2010 190 197
    • (2010) Cancer Lett , vol.297 , Issue.2 , pp. 190-197
    • Feng, Z.1    Xu, S.2    Liu, M.3    Zeng, Y.X.4    Kang, T.5
  • 80
    • 84882236446 scopus 로고    scopus 로고
    • Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma
    • A.K. Cheung, J.C. Ip, H.L. Lung, J.Z. Wu, S.W. Tsao, and M.L. Lung Polo-like kinase inhibitor Ro5203280 has potent antitumor activity in nasopharyngeal carcinoma Mol Cancer Ther 12 8 2013 1393 1401
    • (2013) Mol Cancer Ther , vol.12 , Issue.8 , pp. 1393-1401
    • Cheung, A.K.1    Ip, J.C.2    Lung, H.L.3    Wu, J.Z.4    Tsao, S.W.5    Lung, M.L.6
  • 81
    • 84958034121 scopus 로고    scopus 로고
    • PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy
    • J.P. Chow, W.Y. Man, M. Mao, H. Chen, F. Cheung, and J. Nicholls et al. PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy Mol Cancer Ther 2013
    • (2013) Mol Cancer Ther
    • Chow, J.P.1    Man, W.Y.2    Mao, M.3    Chen, H.4    Cheung, F.5    Nicholls, J.6


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