-
1
-
-
0030099527
-
Transporting therapeutics across the blood-brain barrier
-
Abbott NJ, Romero IA. Transporting therapeutics across the blood-brain barrier. Mol Med Today 1996;2:106-13.
-
(1996)
Mol Med Today
, vol.2
, pp. 106-113
-
-
Abbott, N.J.1
Romero, I.A.2
-
2
-
-
77953912416
-
Strategy for effective brain drug delivery
-
Alam MI, Beg S, Samad A, et al. Strategy for effective brain drug delivery. Eur J Pharm Sci 2010;40:385-403.
-
(2010)
Eur J Pharm Sci
, vol.40
, pp. 385-403
-
-
Alam, M.I.1
Beg, S.2
Samad, A.3
-
3
-
-
0030988750
-
Biomedical applications of nanotechnology-implications for drug targeting and gene therapy
-
Davis SS. Biomedical applications of nanotechnology-implications for drug targeting and gene therapy. Trends Biotechnol 1997; 15:217-24.
-
(1997)
Trends Biotechnol
, vol.15
, pp. 217-224
-
-
Davis, S.S.1
-
4
-
-
27744599588
-
Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease
-
Roney C, Kulkarni P, Arora V, et al. Targeted nanoparticles for drug delivery through the blood-brain barrier for Alzheimer's disease. J Control Release 2005;108:193-214.
-
(2005)
J Control Release
, vol.108
, pp. 193-214
-
-
Roney, C.1
Kulkarni, P.2
Arora, V.3
-
5
-
-
84856938277
-
Formulation, optimization and evaluation of spray-dried mucoadhesive microspheres as intranasal carriers for Valsartan
-
Pardeshi CV, Rajput PV, Belgamwar VS, et al. Formulation, optimization and evaluation of spray-dried mucoadhesive microspheres as intranasal carriers for Valsartan. J Microencapsul 2011; 29:103-14.
-
(2011)
J Microencapsul
, vol.29
, pp. 103-114
-
-
Pardeshi, C.V.1
Rajput, P.V.2
Belgamwar, V.S.3
-
6
-
-
39849091963
-
Evaluation of brain-targeting for the nasal delivery of ergoloid mesylate by the microdialysis method in rats
-
Chen J, Wang X, Wang J, et al. Evaluation of brain-targeting for the nasal delivery of ergoloid mesylate by the microdialysis method in rats. Eur J Pharm Biopharm 2008;68:694-700.
-
(2008)
Eur J Pharm Biopharm
, vol.68
, pp. 694-700
-
-
Chen, J.1
Wang, X.2
Wang, J.3
-
7
-
-
84858742518
-
Brain distribution of ribavirin after intranasal administration
-
Colombo G, Lorenzini L, Zironi E, et al. Brain distribution of ribavirin after intranasal administration. Antiviral Res 2011;92: 408-14.
-
(2011)
Antiviral Res
, vol.92
, pp. 408-414
-
-
Colombo, G.1
Lorenzini, L.2
Zironi, E.3
-
8
-
-
77953916083
-
Potential of nanoparticulate drug delivery systems by intranasal administration
-
Ali J, Ali M, Baboota S. Potential of nanoparticulate drug delivery systems by intranasal administration. Curr Pharm Des 2010;10: 1644-53.
-
(2010)
Curr Pharm des
, vol.10
, pp. 1644-1653
-
-
Ali, J.1
Ali, M.2
Baboota, S.3
-
9
-
-
84905494821
-
The nasal approach to delivering treatment for brain diseases: An anatomic, physiologic, and delivery technology overview
-
Djupesland PG, Messina JC, Mahmoud RA. The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview. Ther Deliv 2014;5:709-33.
-
(2014)
Ther Deliv
, vol.5
, pp. 709-733
-
-
Djupesland, P.G.1
Messina, J.C.2
Mahmoud, R.A.3
-
10
-
-
33748966989
-
Epidemiology of neuro-immunological diseases
-
Flachenecker P. Epidemiology of neuro-immunological diseases. J Neurol 2006;253:2-8.
-
(2006)
J Neurol
, vol.253
, pp. 2-8
-
-
Flachenecker, P.1
-
11
-
-
34547601983
-
Nanomedicine in the diagnosis and therapy of neurodegenerative disorders
-
Kabanov AV, Gendelman HE. Nanomedicine in the diagnosis and therapy of neurodegenerative disorders. Prog Polym Sci 2007;32: 1054-82.
-
(2007)
Prog Polym Sci
, vol.32
, pp. 1054-1082
-
-
Kabanov, A.V.1
Gendelman, H.E.2
-
12
-
-
0036364454
-
The cell biology of alpha-synuclein: A sticky problem?
-
Cole NB, Murphy DD. The cell biology of alpha-synuclein: a sticky problem? Neuromol Med 2002;1:95-109.
-
(2002)
Neuromol Med
, vol.1
, pp. 95-109
-
-
Cole, N.B.1
Murphy, D.D.2
-
13
-
-
84884291279
-
Novel surface modified polymer-lipid hybrid nanoparticles as intranasal carriers for ropinirole hydrochloride: In vitro, ex vivo and in vivo pharmacodynamic evaluation
-
Pardeshi CV, Belgamwar VS, Tekade AR, et al. Novel surface modified polymer-lipid hybrid nanoparticles as intranasal carriers for ropinirole hydrochloride: in vitro, ex vivo and in vivo pharmacodynamic evaluation. J Mater Sci Mater Med 2013;24: 2101-15.
-
(2013)
J Mater Sci Mater Med
, vol.24
, pp. 2101-2115
-
-
Pardeshi, C.V.1
Belgamwar, V.S.2
Tekade, A.R.3
-
14
-
-
67650642274
-
Nanotechnological applications for the treatment of neurodegenerative disorders
-
Modi G, Pillay V, Choonara YE, et al. Nanotechnological applications for the treatment of neurodegenerative disorders. Prog Neurobiol 2009;88:272-85.
-
(2009)
Prog Neurobiol
, vol.88
, pp. 272-285
-
-
Modi, G.1
Pillay, V.2
Choonara, Y.E.3
-
15
-
-
84859979641
-
Nanomaterialmediated CNS delivery of diagnostic and therapeutic agents
-
Biddlestone-Thorpe L, Marchi N, Guo K, et al. Nanomaterialmediated CNS delivery of diagnostic and therapeutic agents. Adv Drug Deliv Rev 2012;64:605-13.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 605-613
-
-
Biddlestone-Thorpe, L.1
Marchi, N.2
Guo, K.3
-
16
-
-
84898486385
-
Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system
-
Gomes MJ, Neves J, Sarmento B. Nanoparticle-based drug delivery to improve the efficacy of antiretroviral therapy in the central nervous system. Int J Nanomed 2014;9:1757-69.
-
(2014)
Int J Nanomed
, vol.9
, pp. 1757-1769
-
-
Gomes, M.J.1
Neves, J.2
Sarmento, B.3
-
17
-
-
80053212172
-
Nanotechnologies for Alzheimer's disease: Diagnosis, therapy, and safety issues
-
Brambilla D, Droumaguet BL, Nicolas J, et al. Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues. Nanomedicine 2011;7:521-40.
-
(2011)
Nanomedicine
, vol.7
, pp. 521-540
-
-
Brambilla, D.1
Droumaguet, B.L.2
Nicolas, J.3
-
18
-
-
84860255699
-
Nanoparticles in the treatment and diagnosis of neurological disorders: Untamed dragon with fire power to heal
-
Kanwar RJ, Sun X, Punj V, et al. Nanoparticles in the treatment and diagnosis of neurological disorders: untamed dragon with fire power to heal. Nanomedicine 2012;8:399-414.
-
(2012)
Nanomedicine
, vol.8
, pp. 399-414
-
-
Kanwar, R.J.1
Sun, X.2
Punj, V.3
-
19
-
-
84864968964
-
Nanotechnology for neurodegenerative disorders
-
Re F, Gregori M, Masserini M. Nanotechnology for neurodegenerative disorders. Maturitas 2012;73:45-51.
-
(2012)
Maturitas
, vol.73
, pp. 45-51
-
-
Re, F.1
Gregori, M.2
Masserini, M.3
-
20
-
-
33846419768
-
Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
-
Braak H, Bohl JR, Muller CM, et al. Lecture 2005: the staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered. Mov Disord 2006;21: 2042-51.
-
(2006)
Mov Disord
, vol.21
, pp. 2042-2051
-
-
Braak, H.1
Bohl, J.R.2
Muller, C.M.3
-
21
-
-
47149118569
-
Potential applications of nanotechnologies to Parkinson's disease therapy
-
Linazasoro G. Potential applications of nanotechnologies to Parkinson's disease therapy. Parkinsonism Relat Disord 2008;14: 383-92.
-
(2008)
Parkinsonism Relat Disord
, vol.14
, pp. 383-392
-
-
Linazasoro, G.1
-
22
-
-
0014082977
-
Parkinsonism: Onset, progression and mortality
-
Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology 1967;17:427-42.
-
(1967)
Neurology
, vol.17
, pp. 427-442
-
-
Hoehn, M.M.1
Yahr, M.D.2
-
24
-
-
0032837272
-
Range of neuropsychiatric disturbances in patients with Parkinson's disease
-
Aarsland D, Larsen JP, Lim NG, et al. Range of neuropsychiatric disturbances in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 1999;67:492-6.
-
(1999)
J Neurol Neurosurg Psychiatry
, vol.67
, pp. 492-496
-
-
Aarsland, D.1
Larsen, J.P.2
Lim, N.G.3
-
25
-
-
0025089310
-
An estimate of the incidence of dementia in idiopathic Parkinson's disease
-
Mayeux R, Chen J, Mirabello E, et al. An estimate of the incidence of dementia in idiopathic Parkinson's disease. Neurology 1990;40: 1513-17.
-
(1990)
Neurology
, vol.40
, pp. 1513-1517
-
-
Mayeux, R.1
Chen, J.2
Mirabello, E.3
-
26
-
-
0023901515
-
An estimate of the prevalence of dementia in idiopathic Parkinson's disease
-
Mayeux R, Stern Y, Rosenstein R, et al. An estimate of the prevalence of dementia in idiopathic Parkinson's disease. Arch Neurol 1988;45:260-2.
-
(1988)
Arch Neurol
, vol.45
, pp. 260-262
-
-
Mayeux, R.1
Stern, Y.2
Rosenstein, R.3
-
27
-
-
0019452463
-
Depression, intellectual impairment and Parkinson disease
-
Mayeux R, Stern Y, Rosen J, et al. Depression, intellectual impairment and Parkinson disease. Neurology 1981;31: 645-50.
-
(1981)
Neurology
, vol.31
, pp. 645-650
-
-
Mayeux, R.1
Stern, Y.2
Rosen, J.3
-
28
-
-
0030020851
-
The occurrence of depression in Parkinson's disease. A community-based study
-
Tandberg E, Larsen JP, Aarsland D, et al. The occurrence of depression in Parkinson's disease. A community-based study. Arch Neurol 1996;53:175-9.
-
(1996)
Arch Neurol
, vol.53
, pp. 175-179
-
-
Tandberg, E.1
Larsen, J.P.2
Aarsland, D.3
-
29
-
-
0022930826
-
Parallel organization of functionally segregated circuits linking basal ganglia and cortex
-
Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann Rev Neurosci 1986;9:357-81.
-
(1986)
Ann Rev Neurosci
, vol.9
, pp. 357-381
-
-
Alexander, G.E.1
DeLong, M.R.2
Strick, P.L.3
-
30
-
-
0034106888
-
Basal ganglia and cerebellar loops: Motor and cognitive circuits
-
Middleton FA, Strick PL. Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Res Rev 2000;31:236-50.
-
(2000)
Brain Res Rev
, vol.31
, pp. 236-250
-
-
Middleton, F.A.1
Strick, P.L.2
-
31
-
-
0026486773
-
Input from the frontal cortex and the parafascicular nucleus to cholinergic interneurons in the dorsal striatum of the rat
-
Lapper SR, Bolam JP. Input from the frontal cortex and the parafascicular nucleus to cholinergic interneurons in the dorsal striatum of the rat. Neuroscience 1992;51:533-45.
-
(1992)
Neuroscience
, vol.51
, pp. 533-545
-
-
Lapper, S.R.1
Bolam, J.P.2
-
32
-
-
0001801251
-
Modification of central catecholaminergic systems by stress and injury: Functional significance and clinical implications
-
In: Bloom EJ, Kupfer DJ, eds.. New York: Raven Press
-
Abercrombie ED, Zigmond MJ. Modification of central catecholaminergic systems by stress and injury: functional significance and clinical implications. In: Bloom EJ, Kupfer DJ, eds. Psychopharmacology: the fourth generation of progress. New York: Raven Press; 1995.
-
(1995)
Psychopharmacology: The Fourth Generation of Progress
-
-
Abercrombie, E.D.1
Zigmond, M.J.2
-
33
-
-
0024326094
-
Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age
-
Ingham CA, Hood SH, Arbuthnott GW. Spine density on neostriatal neurones changes with 6-hydroxydopamine lesions and with age. Brain Res 1989;503:334-8.
-
(1989)
Brain Res
, vol.503
, pp. 334-338
-
-
Ingham, C.A.1
Hood, S.H.2
Arbuthnott, G.W.3
-
34
-
-
13244287684
-
Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease
-
Zaja-Milatovic S, Milatovic D, Schantz AM, et al. Dendritic degeneration in neostriatal medium spiny neurons in Parkinson disease. Neurology 2005;64:545-7.
-
(2005)
Neurology
, vol.64
, pp. 545-547
-
-
Zaja-Milatovic, S.1
Milatovic, D.2
Schantz, A.M.3
-
36
-
-
0025976482
-
Neuronal inclusions of Parkinson's disease
-
Gibb WR, Scott T, Lees AJ. Neuronal inclusions of Parkinson's disease. Mov Disord 1991;6:2-11.
-
(1991)
Mov Disord
, vol.6
, pp. 2-11
-
-
Gibb, W.R.1
Scott, T.2
Lees, A.J.3
-
38
-
-
0030606288
-
Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome
-
Fergusson J, Landon M, Lowe J, et al. Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome. Neurosci Lett 1996;219:167-70.
-
(1996)
Neurosci Lett
, vol.219
, pp. 167-170
-
-
Fergusson, J.1
Landon, M.2
Lowe, J.3
-
39
-
-
0030830270
-
Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly
-
Ii K, Ito H, Tanaka K, et al. Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly. J Neuropathol Exp Neurol 1997;56: 125-31.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 125-131
-
-
Ii, K.1
Ito, H.2
Tanaka, K.3
-
40
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson's disease
-
Wakabayashi K, Engelender S, Yoshimoto M, et al. Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann Neurol 2000; 47:521-3.
-
(2000)
Ann Neurol
, vol.47
, pp. 521-523
-
-
Wakabayashi, K.1
Engelender, S.2
Yoshimoto, M.3
-
41
-
-
84944696743
-
-
New Insight into Parkinson's Disease-NIH Director's Blog [last accessed 19 Aug
-
New Insight into Parkinson's Disease-NIH Director's Blog. Available at: www.directorsblog.nih.gov [last accessed 19 Aug 2014].
-
(2014)
-
-
-
42
-
-
0026751822
-
A population-based investigation of Parkinson's disease with and without dementia
-
Mayeux R, Denaro J, Hemenegildo N, et al. A population-based investigation of Parkinson's disease with and without dementia. Arch Neurol 1992;49:492-7.
-
(1992)
Arch Neurol
, vol.49
, pp. 492-497
-
-
Mayeux, R.1
Denaro, J.2
Hemenegildo, N.3
-
43
-
-
0017077260
-
Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia
-
Carlsson A, Winblad B. Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia. J Neural Transm 1976;38:271-6.
-
(1976)
J Neural Transm
, vol.38
, pp. 271-276
-
-
Carlsson, A.1
Winblad, B.2
-
45
-
-
0030744876
-
Mutation in the alphasynuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alphasynuclein gene identified in families with Parkinson's disease. Science 1997;276:2045-7.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
46
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392: 605-8.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
-
47
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism
-
Bonifati V, Rizzu P, Van Baren MJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism. Science 2002;299:256-9.
-
(2002)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
-
48
-
-
2442668926
-
Hereditary earlyonset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, et al. Hereditary earlyonset Parkinson's disease caused by mutations in PINK1. Science 2004;304:1158-60.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
-
49
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich A, Biskup S, Leitner P, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004;44:601-7.
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
-
50
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
Paisan-Ruiz C, Jain S, Evans EW, et al. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 2004;44:595-600.
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
-
51
-
-
68649114338
-
Genetic models of Parkinson disease
-
Lim KL, Ng CH. Genetic models of Parkinson disease. Biochim Biophys Acta 2009;1792:604-15.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 604-615
-
-
Lim, K.L.1
Ng, C.H.2
-
52
-
-
45749155306
-
A critical reappraisal of current staging of Lewyrelated pathology in human brain
-
Jellinger KA. A critical reappraisal of current staging of Lewyrelated pathology in human brain. Acta Neuropathol 2008;116: 1-16.
-
(2008)
Acta Neuropathol
, vol.116
, pp. 1-16
-
-
Jellinger, K.A.1
-
53
-
-
0034704386
-
Pure autonomic failure in association with human alpha-synucleinopathy
-
Arai K, Kato N, Kashiwado K, et al. Pure autonomic failure in association with human alpha-synucleinopathy. Neurosci Lett 2000; 296:171-3.
-
(2000)
Neurosci Lett
, vol.296
, pp. 171-173
-
-
Arai, K.1
Kato, N.2
Kashiwado, K.3
-
55
-
-
0037422010
-
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
-
Staropoli JF, McDermott C, Martinat C, et al. Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 2003;37: 735-49.
-
(2003)
Neuron
, vol.37
, pp. 735-749
-
-
Staropoli, J.F.1
McDermott, C.2
Martinat, C.3
-
56
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai Y, Soda M, Inoue H, et al. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 2001;105:891-902.
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
-
57
-
-
10744220754
-
The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: Linking protein biosynthesis and neurodegeneration
-
Corti O, Hampe C, Koutnikova H, et al. The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. Hum Mol Genet 2003; 12:1427-37.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1427-1437
-
-
Corti, O.1
Hampe, C.2
Koutnikova, H.3
-
58
-
-
24144497601
-
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death
-
Ko HS, von Coelln R, Sriram R, et al. Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death. J Neurosci 2005; 25:7968-78.
-
(2005)
J Neurosci
, vol.25
, pp. 7968-7978
-
-
Ko, H.S.1
Von Coelln, R.2
Sriram, R.3
-
59
-
-
33745220302
-
Identification of far upstream element-binding protein-1 as an authentic Parkin substrate
-
Ko HS, Kim SW, Sriram SR, et al. Identification of far upstream element-binding protein-1 as an authentic Parkin substrate. J Biol Chem 2006;281:16193-6.
-
(2006)
J Biol Chem
, vol.281
, pp. 16193-16196
-
-
Ko, H.S.1
Kim, S.W.2
Sriram, S.R.3
-
60
-
-
78651257356
-
A photoelectrochemical immunosensor based on Au-doped TiO2 nanotube arrays for the detection of a-synuclein
-
An Y, Tang L, Jiang X, et al. A photoelectrochemical immunosensor based on Au-doped TiO2 nanotube arrays for the detection of a-synuclein. Chemistry 2010;16:14439-46.
-
(2010)
Chemistry
, vol.16
, pp. 14439-14446
-
-
An, Y.1
Tang, L.2
Jiang, X.3
-
61
-
-
34547916390
-
Treatment options in the modern management of Parkinson disease
-
Schapira AH. Treatment options in the modern management of Parkinson disease. Arch Neurol 2007;64:1083-8.
-
(2007)
Arch Neurol
, vol.64
, pp. 1083-1088
-
-
Schapira, A.H.1
-
62
-
-
68649084201
-
Scientific rationale for the development of gene therapy strategies for Parkinson's disease
-
Bjorklund T, Kirik D. Scientific rationale for the development of gene therapy strategies for Parkinson's disease. Biochim Biophys Acta 2009;1792:703-13.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 703-713
-
-
Bjorklund, T.1
Kirik, D.2
-
63
-
-
68949133271
-
Cell replacement therapy for Parkinson's disease
-
Wijeyekoon R, Barker RA. Cell replacement therapy for Parkinson's disease. Biochim Biophys Acta 2009; 1792:688-702.
-
(2009)
Biochim Biophys Acta
, vol.1792
, pp. 688-702
-
-
Wijeyekoon, R.1
Barker, R.A.2
-
64
-
-
79958284580
-
Neurotherapeutic applications of nanoparticles in Alzheimer's disease
-
Sahni JK, Doggui S, Ali J. Neurotherapeutic applications of nanoparticles in Alzheimer's disease. J Control Release 2011;152: 208-31.
-
(2011)
J Control Release
, vol.152
, pp. 208-231
-
-
Sahni, J.K.1
Doggui, S.2
Ali, J.3
-
65
-
-
75149127160
-
Chitosan nanoparticles as a new delivery system for the anti-Alzheimer drug tacrine
-
Wilson B, Samanta MK, Santhi K, et al. Chitosan nanoparticles as a new delivery system for the anti-Alzheimer drug tacrine. Nanomedicine 2009;6:144-52.
-
(2009)
Nanomedicine
, vol.6
, pp. 144-152
-
-
Wilson, B.1
Samanta, M.K.2
Santhi, K.3
-
66
-
-
0037190020
-
Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles
-
Banerjee T, Mitra S, Kumar Singh A, et al. Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles. Int J Pharm 2002;243:93-105.
-
(2002)
Int J Pharm
, vol.243
, pp. 93-105
-
-
Banerjee, T.1
Mitra, S.2
Kumar Singh, A.3
-
68
-
-
0036707316
-
Biodegradable nanoparticles for drug delivery and targeting
-
Hans ML, Lowman AM. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci 2002;6: 319-27.
-
(2002)
Curr Opin Solid State Mater Sci
, vol.6
, pp. 319-327
-
-
Hans, M.L.1
Lowman, A.M.2
-
70
-
-
78649445308
-
Surfactant effects on the physical characteristics of Amphotericin B-containing nanostructured lipid carriers
-
Tan SW, Billa N, Roberts CR. Surfactant effects on the physical characteristics of Amphotericin B-containing nanostructured lipid carriers. Colloids Surf A 2010;372:73-9.
-
(2010)
Colloids Surf A
, vol.372
, pp. 73-79
-
-
Tan, S.W.1
Billa, N.2
Roberts, C.R.3
-
71
-
-
40849097322
-
Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease
-
Wilson B, Samanta MK, Santhi K, et al. Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain Res 2008;1200:159-68.
-
(2008)
Brain Res
, vol.1200
, pp. 159-168
-
-
Wilson, B.1
Samanta, M.K.2
Santhi, K.3
-
72
-
-
12344307628
-
Drug targeting to brain with targeted nanoparticles
-
Olivier JC. Drug targeting to brain with targeted nanoparticles. NeuroRx 2005;2:108-19.
-
(2005)
NeuroRx
, vol.2
, pp. 108-119
-
-
Olivier, J.C.1
-
74
-
-
84879401096
-
Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood-brain barrier: An excellent platform for brain targeting
-
Pardeshi CV, Belgamwar VS. Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood-brain barrier: an excellent platform for brain targeting. Expert Opin Drug Deliv 2013;10:957-72.
-
(2013)
Expert Opin Drug Deliv
, vol.10
, pp. 957-972
-
-
Pardeshi, C.V.1
Belgamwar, V.S.2
-
75
-
-
68649090916
-
Nanoparticles for direct nose-to-brain delivery of drugs
-
Mistry A, Stolnik S, Illum L. Nanoparticles for direct nose-to-brain delivery of drugs. Int J Pharm 2009;379:146-57.
-
(2009)
Int J Pharm
, vol.379
, pp. 146-157
-
-
Mistry, A.1
Stolnik, S.2
Illum, L.3
-
76
-
-
0033975029
-
Development of an in situ mouse brain perfusion model and its application to mdr1a Pglycoprotein-deficient mice
-
Dagenais C, Rousselle C, Pollack GM, et al. Development of an in situ mouse brain perfusion model and its application to mdr1a Pglycoprotein-deficient mice. J Cereb Blood Flow Metab 2000;20: 381-6.
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 381-386
-
-
Dagenais, C.1
Rousselle, C.2
Pollack, G.M.3
-
77
-
-
33644900716
-
The role of blood-brain barrier studies in the pharmaceutical industry
-
Reichel A. The role of blood-brain barrier studies in the pharmaceutical industry. Curr Drug Metab 2006;7:183-203.
-
(2006)
Curr Drug Metab
, vol.7
, pp. 183-203
-
-
Reichel, A.1
-
78
-
-
19944425121
-
The impact of p-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: Evaluation using the mdr1a/1b knockout mouse model
-
Doran A, Obach RC, Smith BJ, et al. The impact of p-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the mdr1a/1b knockout mouse model. Drug Metab Dispos 2005;33:165-74.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 165-174
-
-
Doran, A.1
Obach, R.C.2
Smith, B.J.3
-
79
-
-
11144290156
-
Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice
-
Maurer TS, DeBartolo DB, Tess DA, et al. Relationship between exposure and nonspecific binding of thirty-three central nervous system drugs in mice. Drug Metab Dispos 2005;33:175-81.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 175-181
-
-
Maurer, T.S.1
DeBartolo, D.B.2
Tess, D.A.3
-
81
-
-
57849116155
-
Analytical characterization of chitosan nanoparticles for peptide drug delivery applications
-
Ieva E, Trapani A, Cioffi N, et al. Analytical characterization of chitosan nanoparticles for peptide drug delivery applications. Anal Bioanal Chem 2009;393:207-15.
-
(2009)
Anal Bioanal Chem
, vol.393
, pp. 207-215
-
-
Ieva, E.1
Trapani, A.2
Cioffi, N.3
-
82
-
-
84872412539
-
Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: Pharmacodynamic, pharmacokinetic and scintigraphy study in mice model
-
Md S, Khan RA, Mustafa G, et al. Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: pharmacodynamic, pharmacokinetic and scintigraphy study in mice model. Eur J Pharm Biopharm 2013;48:393-405.
-
(2013)
Eur J Pharm Biopharm
, vol.48
, pp. 393-405
-
-
Md, S.1
Khan, R.A.2
Mustafa, G.3
-
83
-
-
84901288353
-
Optimised nanoformulation of bromocriptine for direct nose-to-brain delivery: Biodistribution, pharmacokinetic and dopamine estimation by ultra-HPLC/mass spectrometry method
-
Md S, Haque S, Fazil M, et al. Optimised nanoformulation of bromocriptine for direct nose-to-brain delivery: biodistribution, pharmacokinetic and dopamine estimation by ultra-HPLC/mass spectrometry method. Expert Opin Drug Deliv 2014;11:827-42.
-
(2014)
Expert Opin Drug Deliv
, vol.11
, pp. 827-842
-
-
Md, S.1
Haque, S.2
Fazil, M.3
-
84
-
-
84948171398
-
Design, characterization, and evaluation of intranasal delivery of ropinirole-loaded mucoadhesive nanoparticles for brain targeting
-
[Epub ahead of print]
-
Jafarieh O, Md S, Ali M, et al. Design, characterization, and evaluation of intranasal delivery of ropinirole-loaded mucoadhesive nanoparticles for brain targeting. Drug Dev Ind Pharm 2014. [Epub ahead of print]. doi: 10.3109/03639045.2014.991400.
-
(2014)
Drug Dev Ind Pharm
-
-
Jafarieh, O.1
Md, S.2
Ali, M.3
-
85
-
-
84902249410
-
Formulation and characterization of intranasal mucoadhesive nanoparticulates and thermo-reversible gel of levodopa for brain delivery
-
Sharma S, Lohan S, Murthy RSR. Formulation and characterization of intranasal mucoadhesive nanoparticulates and thermo-reversible gel of levodopa for brain delivery. Drug Dev Ind Pharm 2014;40: 869-78.
-
(2014)
Drug Dev Ind Pharm
, vol.40
, pp. 869-878
-
-
Sharma, S.1
Lohan, S.2
Murthy, R.S.R.3
-
86
-
-
84954311466
-
Brain targeted nanoparticulate drug delivery system of rasagiline via intranasal route
-
[Epub ahead of print]
-
Mittal D, Md S, Hasan Q, et al. Brain targeted nanoparticulate drug delivery system of rasagiline via intranasal route. Drug Deliv 2014. [Epub ahead of print]. doi: 10.3109/10717544.2014.907372.
-
(2014)
Drug Deliv
-
-
Mittal, D.1
Md, S.2
Hasan, Q.3
-
87
-
-
84862673737
-
PLGA-based nanoparticles: An overview of biomedical applications
-
Danhier F, Ansorena E, Silva JM, et al. PLGA-based nanoparticles: an overview of biomedical applications. J Control Release 2012; 161:505-22.
-
(2012)
J Control Release
, vol.161
, pp. 505-522
-
-
Danhier, F.1
Ansorena, E.2
Silva, J.M.3
-
88
-
-
80055118993
-
Development and evaluation of olanzapine-loaded PLGA nanoparticles for nose-to-brain delivery: In vitro and in vivo studies
-
Seju U, Kumar A, Sawant KK. Development and evaluation of olanzapine-loaded PLGA nanoparticles for nose-to-brain delivery: in vitro and in vivo studies. Acta Biomater 2011;7:4169-76.
-
(2011)
Acta Biomater
, vol.7
, pp. 4169-4176
-
-
Seju, U.1
Kumar, A.2
Sawant, K.K.3
-
89
-
-
79956113494
-
Odorranalectin-conjugated nanoparticles: Preparation, brain delivery and pharmacodynamic study on Parkinson's disease following intranasal administration
-
Wen Z, Yan Z, Hu K, et al. Odorranalectin-conjugated nanoparticles: preparation, brain delivery and pharmacodynamic study on Parkinson's disease following intranasal administration. J Control Release 2011;151:131-8.
-
(2011)
J Control Release
, vol.151
, pp. 131-138
-
-
Wen, Z.1
Yan, Z.2
Hu, K.3
-
90
-
-
84928377926
-
Increasing the efficiency of Parkinson's disease treatment using a poly(lactic-coglycolic acid) (PLGA) based L-DOPA delivery system
-
Gambaryan PY, Kondrasheva IG, Severin ES, et al. Increasing the efficiency of Parkinson's disease treatment using a poly(lactic-coglycolic acid) (PLGA) based L-DOPA delivery system. Exp Neurobiol 2014;23:246-52.
-
(2014)
Exp Neurobiol
, vol.23
, pp. 246-252
-
-
Gambaryan, P.Y.1
Kondrasheva, I.G.2
Severin, E.S.3
-
91
-
-
84900322139
-
Gelatin nanostructured lipid carriersmediated intranasal delivery of basic fibroblast growth factor enhances functional recovery in hemiparkinsonian rats
-
Zhao YZ, Li X, Lu CT, et al. Gelatin nanostructured lipid carriersmediated intranasal delivery of basic fibroblast growth factor enhances functional recovery in hemiparkinsonian rats. Nanomedicine 2014;10:755-64.
-
(2014)
Nanomedicine
, vol.10
, pp. 755-764
-
-
Zhao, Y.Z.1
Li, X.2
Lu, C.T.3
-
92
-
-
84872243324
-
Novel surface modified solid lipid nanoparticles as intranasal carriers for ropinirole hydrochloride: Application of factorial design approach
-
Pardeshi CV, Rajput PV, Belgamwar VS, et al. Novel surface modified solid lipid nanoparticles as intranasal carriers for ropinirole hydrochloride: application of factorial design approach. Drug Deliv 2013;20:47-56.
-
(2013)
Drug Deliv
, vol.20
, pp. 47-56
-
-
Pardeshi, C.V.1
Rajput, P.V.2
Belgamwar, V.S.3
-
93
-
-
84876545158
-
Solid lipid based nanocarriers: An overview
-
Pardeshi C, Rajput P, Belgamwar V, et al. Solid lipid based nanocarriers: an overview. Acta Pharm 2012;62: 433-72.
-
(2012)
Acta Pharm
, vol.62
, pp. 433-472
-
-
Pardeshi, C.1
Rajput, P.2
Belgamwar, V.3
-
94
-
-
51849084844
-
Self-assembled lipid polymer hybrid nanoparticles: A robust drug delivery platform
-
Zhang L, Chan JM, Gu FX, et al. Self-assembled lipid polymer hybrid nanoparticles: a robust drug delivery platform. ACS Nano 2008;8:1696-702.
-
(2008)
ACS Nano
, vol.8
, pp. 1696-1702
-
-
Zhang, L.1
Chan, J.M.2
Gu, F.X.3
-
95
-
-
0034614208
-
Microemulsion based media as a novel drug delivery system
-
Lawrence MJ, Rees GD. Microemulsion based media as a novel drug delivery system. Adv Drug Del Rev 2000;45: 89-121.
-
(2000)
Adv Drug Del Rev
, vol.45
, pp. 89-121
-
-
Lawrence, M.J.1
Rees, G.D.2
-
96
-
-
65749099862
-
Formulation and characterization of nanoemulsion-based drug delivery system of risperidone
-
Kumar M, Pathak K. Formulation and characterization of nanoemulsion-based drug delivery system of risperidone. Drug Dev Ind Pharm 2009;35:387-95.
-
(2009)
Drug Dev Ind Pharm
, vol.35
, pp. 387-395
-
-
Kumar, M.1
Pathak, K.2
-
97
-
-
84861683682
-
Formulation development of chitosan coated intranasal ropinirole nanoemulsion for better management option of Parkinson: An in vitro ex vivo evaluation
-
Mustafa G, Baboota S, Ahuja A, et al. Formulation development of chitosan coated intranasal ropinirole nanoemulsion for better management option of parkinson: an in vitro ex vivo evaluation. Curr Nanosci 2014;3:348-60.
-
(2014)
Curr Nanosci
, vol.3
, pp. 348-360
-
-
Mustafa, G.1
Baboota, S.2
Ahuja, A.3
|