Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Quan, Yizhou ^a,b   Xia, Li ^c   Shao, Jiaxiang ^a,b   Yin, Shankai ^c   Cheng, C Yan ^d   Xia, Weiliang ^a,b   Gao, Wei Qiang ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^d POPULATION COUNCIL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1-(2,4-DICHLOROBENZYL)INDAZOLE-3-CARBOHYDRAZIDE; ANTIINFECTIVE AGENT; GENTAMICIN; HYDRAZINE DERIVATIVE; INDAZOLE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SIRTUIN 3; SMALL INTERFERING RNA;

ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; COCHLEA; CORTI ORGAN; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EPITHELIUM; GENETICS; HAIR CELL; HEARING LOSS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; UPREGULATION;

ANIMALS; ANTI-BACTERIAL AGENTS; CELLS, CULTURED; COCHLEA; DISEASE MODELS, ANIMAL; EPITHELIUM; GENTAMICINS; HAIR CELLS, AUDITORY; HEARING LOSS; HYDRAZINES; IMMUNOHISTOCHEMISTRY; INDAZOLES; MICE; MICE, INBRED C57BL; ORGAN OF CORTI; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SIRTUIN 3; UP-REGULATION;

EID: 84944466391     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep08181     Document Type: Article

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