Coupling the modules of EMT and stemness: A tunable 'stemness window' model

Oncotarget

Volumn 6, Issue 28, 2015, Pages 25161-25174

  Jolly, Mohit Kumar ^a,b   Jia, Dongya ^a   Boareto, Marcelo ^a,d   Mani, Sendurai A ^e   Pienta, Kenneth J ^f   Ben Jacob, Eshel ^a,c   Levine, Herbert ^a,b  

^a RICE UNIVERSITY   (United States)

^b Rice University   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer stem cells; Multistability; OVOL; Partial EMT; Stemness window

Indexed keywords

BINDING PROTEIN; MICRORNA; MICRORNA 200; MICRORNA LET 7; OVOL PROTEIN; PROTEIN LIN28; PROTEIN ZEB; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; HOMEODOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIN-28 PROTEIN, HUMAN; MIRN200 MICRORNA, HUMAN; MIRNLET7 MICRORNA, HUMAN; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; ZEB1 PROTEIN, HUMAN;

ARTICLE; CELLULAR PARAMETERS; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; MOLECULAR MODEL; PHENOTYPE; PROTEIN FUNCTION; STEMNESS; TUMOR PROMOTION; BIOLOGICAL MODEL; CANCER STEM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; NEOPLASM; PATHOLOGY; SIGNAL TRANSDUCTION;

EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; NEOPLASMS; NEOPLASTIC STEM CELLS; NF-KAPPA B; PHENOTYPE; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS; ZINC FINGER E-BOX-BINDING HOMEOBOX 1;

EID: 84944463968     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4629     Document Type: Article

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