-
1
-
-
84857768074
-
Network physiology reveals relations between network topology and physiological function
-
Bashan A, Bartsch R P, Kantelhardt J W, Havlin S and Ivanov P C 2012 Network physiology reveals relations between network topology and physiological function Nat. Commun. 3 702
-
(2012)
Nat. Commun.
, vol.3
, pp. 702
-
-
Bashan, A.1
Bartsch, R.P.2
Kantelhardt, J.W.3
Havlin, S.4
Ivanov, P.C.5
-
2
-
-
84897692848
-
Network physiology: Mapping interactions between networks of physiologic networks
-
ed G D'Agostino and A Scala (Switzerland: Springer)
-
Ivanov P C and Bartsch R P 2014 Network physiology: mapping interactions between networks of physiologic networks Networks of Networks: the last Frontier of Complexity ed G D'Agostino and A Scala (Switzerland: Springer) pp 203-22
-
(2014)
Networks of Networks: The Last Frontier of Complexity
, pp. 203-222
-
-
Ivanov, P.C.1
Bartsch, R.P.2
-
3
-
-
54249105943
-
From signals to patterns: Space, time, and mathematics in developmental biology
-
Lewis J 2008 From signals to patterns: space, time, and mathematics in developmental biology Science 322 399-403
-
(2008)
Science
, vol.322
, pp. 399-403
-
-
Lewis, J.1
-
4
-
-
79952638264
-
Cellular decision making and biological noise: From microbes to mammals
-
Balázsi G, van Oudenaarden A and Collins J J 2011 Cellular decision making and biological noise: from microbes to mammals Cell 144 910-25
-
(2011)
Cell
, vol.144
, pp. 910-925
-
-
Balázsi, G.1
Van Oudenaarden, A.2
Collins, J.J.3
-
5
-
-
84907059374
-
Toward decoding the principles of cancer metastasis circuits
-
Lu M, Jolly M K, Onuchic J and Ben-Jacob E 2014 Toward decoding the principles of cancer metastasis circuits Cancer Res. 74 4574-87
-
(2014)
Cancer Res.
, vol.74
, pp. 4574-4587
-
-
Lu, M.1
Jolly, M.K.2
Onuchic, J.3
Ben-Jacob, E.4
-
7
-
-
80051531363
-
Notch signaling: Simplicity in design, versatility in function
-
Andersson E R, Sandberg R and Lendahl U 2011 Notch signaling: simplicity in design, versatility in function Development 138 3593-612
-
(2011)
Development
, vol.138
, pp. 3593-3612
-
-
Andersson, E.R.1
Sandberg, R.2
Lendahl, U.3
-
8
-
-
81955168018
-
From Notch signaling to fine-grained patterning: Modeling meets experiments
-
Shaya O and Sprinzak D 2011 From Notch signaling to fine-grained patterning: modeling meets experiments Curr. Opin. Genet. Dev. 21 732-9
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 732-739
-
-
Shaya, O.1
Sprinzak, D.2
-
9
-
-
9144246932
-
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
-
Timmerman L A et al 2004 Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation Genes Dev. 18 99-115
-
(2004)
Genes Dev.
, vol.18
, pp. 99-115
-
-
Timmerman, L.A.1
-
10
-
-
84901387665
-
Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear
-
Petrovic J, Formosa-Jordan P, Luna-Escalante J C, Abelló G, Ibañes M, Neves J and Giraldez F 2014 Ligand-dependent Notch signaling strength orchestrates lateral induction and lateral inhibition in the developing inner ear Development 141 2313-24
-
(2014)
Development
, vol.141
, pp. 2313-2324
-
-
Petrovic, J.1
Formosa-Jordan, P.2
Luna-Escalante, J.C.3
Abelló, G.4
Ibañes, M.5
Neves, J.6
Giraldez, F.7
-
11
-
-
84856116206
-
Notch activation of Jagged1 contributes to the assembly of the arterial wall
-
Manderfield L J, High F A, Engleka K A, Liu F, Li L, Rentschler S and Epstein J A 2012 Notch activation of Jagged1 contributes to the assembly of the arterial wall Circulation 125 314-23
-
(2012)
Circulation
, vol.125
, pp. 314-323
-
-
Manderfield, L.J.1
High, F.A.2
Engleka, K.A.3
Liu, F.4
Li, L.5
Rentschler, S.6
Epstein, J.A.7
-
12
-
-
77957654320
-
Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear
-
Hartman B H, Reh T A and Bermingham-McDonogh O 2010 Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear Proc. Natl Acad. Sci. USA 107 15792-7
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15792-15797
-
-
Hartman, B.H.1
Reh, T.A.2
Bermingham-McDonogh, O.3
-
13
-
-
0036065333
-
Periodic lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to Notch signaling
-
Morales A V, Yasuda Y and Ish-horowicz D 2002 Periodic lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to Notch signaling Dev. Cell 3 63-74
-
(2002)
Dev. Cell
, vol.3
, pp. 63-74
-
-
Morales, A.V.1
Yasuda, Y.2
Ish-Horowicz, D.3
-
14
-
-
84922373656
-
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states
-
LeBon L, Lee T V, Sprinzak D, Jafar-Nejad H and Elowitz M B 2014 Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states eLife 3 e02950
-
(2014)
ELife
, vol.3
-
-
Lebon, L.1
Lee, T.V.2
Sprinzak, D.3
Jafar-Nejad, H.4
Elowitz, M.B.5
-
16
-
-
0034253589
-
Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2
-
Hicks C, Johnston S H, diSibio G, Collazo A, Vogt T F and Weinmaster G 2000 Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2 Nat. Cell Biol. 2 515-20
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 515-520
-
-
Hicks, C.1
Johnston, S.H.2
Disibio, G.3
Collazo, A.4
Vogt, T.F.5
Weinmaster, G.6
-
17
-
-
0035854693
-
Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation
-
Shimizu K, Chiba S, Saito T, Kumano K, Takahashi T and Hirai H 2001 Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation J. Biol. Chem. 276 25753-8
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25753-25758
-
-
Shimizu, K.1
Chiba, S.2
Saito, T.3
Kumano, K.4
Takahashi, T.5
Hirai, H.6
-
18
-
-
79955972801
-
Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions
-
Van De Walle et al 2011 Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions Blood 117 4449-59
-
(2011)
Blood
, vol.117
, pp. 4449-4459
-
-
Van De Walle1
-
20
-
-
79751472667
-
Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
-
Sethi N, Dai X, Winter C G and Kang Y 2011 Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells Cancer Cell 19 192-205
-
(2011)
Cancer Cell
, vol.19
, pp. 192-205
-
-
Sethi, N.1
Dai, X.2
Winter, C.G.3
Kang, Y.4
-
21
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta G P and Massagué J 2006 Cancer metastasis: building a framework Cell 127 679-95
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massagué, J.2
-
22
-
-
84883097117
-
NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype
-
Yamamoto M, Taguchi Y, Ito-Kureha T, Semba K, Yamaguchi N and Inoue J 2013 NF-κB non-cell-autonomously regulates cancer stem cell populations in the basal-like breast cancer subtype Nat. Commun. 4 2299
-
(2013)
Nat. Commun.
, vol.4
, pp. 2299
-
-
Yamamoto, M.1
Taguchi, Y.2
Ito-Kureha, T.3
Semba, K.4
Yamaguchi, N.5
Inoue, J.6
-
23
-
-
84873728505
-
Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1
-
Lu J et al 2013 Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1 Cancer Cell 23 171-85
-
(2013)
Cancer Cell
, vol.23
, pp. 171-185
-
-
Lu, J.1
-
24
-
-
84911395686
-
Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties
-
Ghiabi P, Jiang J, Pasquier J, Maleki M, Abu-Kaoud N, Rafii S and Rafii A 2014 Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties PLoS One 9 e112424
-
(2014)
PLoS One
, vol.9
-
-
Ghiabi, P.1
Jiang, J.2
Pasquier, J.3
Maleki, M.4
Abu-Kaoud, N.5
Rafii, S.6
Rafii, A.7
-
25
-
-
84922352048
-
Jagged-Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype
-
Boareto M, Jolly M K, Lu M, Onuchic J N, Clementi C and Ben-Jacob E 2015 Jagged-Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype Proc. Natl Acad. Sci. 112 E402-9
-
(2015)
Proc. Natl Acad. Sci.
, vol.112
, pp. E402-E409
-
-
Boareto, M.1
Jolly, M.K.2
Lu, M.3
Onuchic, J.N.4
Clementi, C.5
Ben-Jacob, E.6
-
26
-
-
77952092577
-
Cis-interactions between Notch and Delta generate mutually exclusive signalling states
-
Sprinzak D, Lakhanpal A, Lebon L, Santat L A, Fontes M E, Anderson G A, Garcia-Ojalvo J and Elowitz M B 2010 Cis-interactions between Notch and Delta generate mutually exclusive signalling states Nature 465 86-90
-
(2010)
Nature
, vol.465
, pp. 86-90
-
-
Sprinzak, D.1
Lakhanpal, A.2
Lebon, L.3
Santat, L.A.4
Fontes, M.E.5
Anderson, G.A.6
Garcia-Ojalvo, J.7
Elowitz, M.B.8
-
27
-
-
84887278742
-
MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination
-
Lu M, Jolly M K, Levine H, Onuchic J N and Ben-Jacob E 2013 MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination Proc. Natl Acad. Sci. USA 110 18174-9
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 18174-18179
-
-
Lu, M.1
Jolly, M.K.2
Levine, H.3
Onuchic, J.N.4
Ben-Jacob, E.5
-
28
-
-
80053381893
-
Notch signaling and Notch signaling modifiers
-
Wang M M 2011 Notch signaling and Notch signaling modifiers Int. J. Biochem. Cell Biol. 43 1550-62
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 1550-1562
-
-
Wang, M.M.1
-
29
-
-
51349106560
-
Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes
-
Urs S, Roudabush A, O'Neill C F, Pinz I, Prudovsky I, Kacer D, Tang Y, Liaw L and Small D 2008 Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes Am. J. Pathol. 173 865-78
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 865-878
-
-
Urs, S.1
Roudabush, A.2
O'Neill, C.F.3
Pinz, I.4
Prudovsky, I.5
Kacer, D.6
Tang, Y.7
Liaw, L.8
Small, D.9
-
31
-
-
0037097242
-
A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling
-
Hicks C, Ladi E, Lindsell C, Hsieh J J D, Hayward S D, Collazo A and Weinmaster G 2002 A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signaling J. Neurosci. Res. 68 655-67
-
(2002)
J. Neurosci. Res.
, vol.68
, pp. 655-667
-
-
Hicks, C.1
Ladi, E.2
Lindsell, C.3
Hsieh, J.J.D.4
Hayward, S.D.5
Collazo, A.6
Weinmaster, G.7
-
32
-
-
84890637291
-
Membrane tethered Delta activates Notch and reveals a role for spatio-mechanical regulation of the signaling pathway
-
Narui Y and Salaita K 2013 Membrane tethered Delta activates Notch and reveals a role for spatio-mechanical regulation of the signaling pathway Biophys. J. 105 2655-65
-
(2013)
Biophys. J.
, vol.105
, pp. 2655-2665
-
-
Narui, Y.1
Salaita, K.2
-
33
-
-
84866119498
-
Hybrid models and biological model reduction with PyDSTool
-
Clewley R 2012 Hybrid models and biological model reduction with PyDSTool PLoS Comput. Biol. 8 e1002628
-
(2012)
PLoS Comput. Biol.
, vol.8
-
-
Clewley, R.1
-
34
-
-
0028641294
-
Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision
-
Wilkinson H A, Fitzgerald K and Greenwald I 1994 Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision Cell 79 1187-98
-
(1994)
Cell
, vol.79
, pp. 1187-1198
-
-
Wilkinson, H.A.1
Fitzgerald, K.2
Greenwald, I.3
-
35
-
-
0030597511
-
Pattern formation by lateral inhibition with feedback: A mathematical model of delta-notch intercellular signalling
-
Collier J R, Monk N A, Maini P K and Lewis J H 1996 Pattern formation by lateral inhibition with feedback: a mathematical model of delta-notch intercellular signalling J. Theor. Biol. 183 429-46
-
(1996)
J. Theor. Biol.
, vol.183
, pp. 429-446
-
-
Collier, J.R.1
Monk, N.A.2
Maini, P.K.3
Lewis, J.H.4
-
36
-
-
77957607057
-
Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
-
Jakobsson L et al 2010 Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting Nat. Cell Biol. 12 943-53
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 943-953
-
-
Jakobsson, L.1
-
38
-
-
84903388386
-
An expanded Notch-Delta model exhibiting long-range patterning and incorporating MicroRNA regulation
-
Chen J S, Gumbayan A M, Zeller R W and Mahaffy J M 2014 An expanded Notch-Delta model exhibiting long-range patterning and incorporating MicroRNA regulation PLoS Comput. Biol. 10 e1003655
-
(2014)
PLoS Comput. Biol.
, vol.10
-
-
Chen, J.S.1
Gumbayan, A.M.2
Zeller, R.W.3
Mahaffy, J.M.4
-
39
-
-
0033955578
-
Lateral induction by juxtacrine signaling is a new mechanism for pattern formation
-
Owen M R, Sherratt J A and Wearing H J 2000 Lateral induction by juxtacrine signaling is a new mechanism for pattern formation Dev. Biol. 217 54-61
-
(2000)
Dev. Biol.
, vol.217
, pp. 54-61
-
-
Owen, M.R.1
Sherratt, J.A.2
Wearing, H.J.3
-
40
-
-
84872260133
-
On the role of lateral stabilization during early patterning in the pancreas
-
de Back W, Zhou J X and Brusch L 2013 On the role of lateral stabilization during early patterning in the pancreas J. R. Soc. Interface 10 20120766
-
(2013)
J. R. Soc. Interface
, vol.10
-
-
De Back, W.1
Zhou, J.X.2
Brusch, L.3
-
42
-
-
84899768284
-
Competition in Notch signaling with Cis enriches cell fate decisions
-
Formosa-Jordan P and Ibañes M 2014 Competition in Notch signaling with Cis enriches cell fate decisions PLoS One 9 e95744
-
(2014)
PLoS One
, vol.9
-
-
Formosa-Jordan, P.1
Ibañes, M.2
-
43
-
-
84883159474
-
Tristability in cancer-associated MicroRNA-TF chimera toggle switch
-
Lu M, Jolly M K, Gomoto R, Huang B, Onuchic J and Ben-Jacob E 2013 Tristability in cancer-associated MicroRNA-TF chimera toggle switch J. Phys. Chem. B 117 13164-74
-
(2013)
J. Phys. Chem. B
, vol.117
, pp. 13164-13174
-
-
Lu, M.1
Jolly, M.K.2
Gomoto, R.3
Huang, B.4
Onuchic, J.5
Ben-Jacob, E.6
-
44
-
-
84923382712
-
The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transition
-
Huang B, Lu M, Jolly M K, Tsarfaty I, Onuchic J and Ben-Jacob E 2014 The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transition Sci. Rep. 4 6449
-
(2014)
Sci. Rep.
, vol.4
, pp. 6449
-
-
Huang, B.1
Lu, M.2
Jolly, M.K.3
Tsarfaty, I.4
Onuchic, J.5
Ben-Jacob, E.6
-
45
-
-
79956273344
-
A general model for binary cell fate decision gene circuits with degeneracy: Indeterminacy and switch behavior in the absence of cooperativity
-
Andrecut M, Halley J D, Winkler D A and Huang S 2011 A general model for binary cell fate decision gene circuits with degeneracy: indeterminacy and switch behavior in the absence of cooperativity PLoS One 6 e19358
-
(2011)
PLoS One
, vol.6
-
-
Andrecut, M.1
Halley, J.D.2
Winkler, D.A.3
Huang, S.4
-
46
-
-
70349559776
-
Why are cellular switches boolean? General conditions for multistable genetic circuits
-
Macía J, Widder S and Solé R 2009 Why are cellular switches boolean? General conditions for multistable genetic circuits J. Theor. Biol. 261 126-35
-
(2009)
J. Theor. Biol.
, vol.261
, pp. 126-135
-
-
MacÍa, J.1
Widder, S.2
Solé, R.3
-
47
-
-
84922345421
-
Towards elucidating the connection between epithelial-mesenchymal transitions and stemness
-
Jolly M K, Huang B, Lu M, Mani S A, Levine H and Ben-Jacob E 2014 Towards elucidating the connection between epithelial-mesenchymal transitions and stemness J. R. Soc. Interface 11 20140962
-
(2014)
J. R. Soc. Interface
, vol.11
-
-
Jolly, M.K.1
Huang, B.2
Lu, M.3
Mani, S.A.4
Levine, H.5
Ben-Jacob, E.6
-
48
-
-
66449123068
-
The Notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
-
Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M and Adams R H 2009 The Notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis Cell 137 1124-35
-
(2009)
Cell
, vol.137
, pp. 1124-1135
-
-
Benedito, R.1
Roca, C.2
Sörensen, I.3
Adams, S.4
Gossler, A.5
Fruttiger, M.6
Adams, R.H.7
-
49
-
-
84877143362
-
Notch as a hub for signaling in angiogenesis
-
Benedito R and Hellström M 2013 Notch as a hub for signaling in angiogenesis Exp. Cell Res. 319 1281-8
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 1281-1288
-
-
Benedito, R.1
Hellström, M.2
-
50
-
-
84882680826
-
Transdifferentiation of pancreatic cells by loss of contact-mediated signaling
-
De Back W, Zimm R and Brusch L 2013 Transdifferentiation of pancreatic cells by loss of contact-mediated signaling BMC Syst. Biol. 7 77
-
(2013)
BMC Syst. Biol.
, vol.7
, pp. 77
-
-
De Back, W.1
Zimm, R.2
Brusch, L.3
-
51
-
-
69049118162
-
Lunatic fringe promotes the lateral inhibition of neurogenesis
-
Nikolaou N, Watanabe-Asaka T, Gerety S, Distel M, Köster R W and Wilkinson D G 2009 Lunatic fringe promotes the lateral inhibition of neurogenesis Development 136 2523-33
-
(2009)
Development
, vol.136
, pp. 2523-2533
-
-
Nikolaou, N.1
Watanabe-Asaka, T.2
Gerety, S.3
Distel, M.4
Köster, R.W.5
Wilkinson, D.G.6
-
52
-
-
84907835711
-
Construction of an Effective Landscape for Multistate Genetic Switches
-
Lu M, Onuchic J and Ben-Jacob E 2014 Construction of an Effective Landscape for Multistate Genetic Switches Phys. Rev. Lett. 113 078102
-
(2014)
Phys. Rev. Lett.
, vol.113
-
-
Lu, M.1
Onuchic, J.2
Ben-Jacob, E.3
-
53
-
-
84861398396
-
Lunatic fringe deficiency cooperates with the met/caveolin gene amplicon to induce basal-like breast cancer
-
Xu K et al 2012 Lunatic fringe deficiency cooperates with the met/caveolin gene amplicon to induce basal-like breast cancer Cancer Cell 21 626-41
-
(2012)
Cancer Cell
, vol.21
, pp. 626-641
-
-
Xu, K.1
-
54
-
-
84921655775
-
Manic fringe inhibits tumor growth by suppressing Notch3 degradation in lung cancer
-
Yi F, Amarasinghe B and Dang T P 2013 Manic fringe inhibits tumor growth by suppressing Notch3 degradation in lung cancer Am. J. Cancer Res. 3 490-9
-
(2013)
Am. J. Cancer Res.
, vol.3
, pp. 490-499
-
-
Yi, F.1
Amarasinghe, B.2
Dang, T.P.3
-
55
-
-
84900446105
-
Tumor-suppressive activity of lunatic fringe in prostate through differential modulation of Notch receptor activation
-
Zhang S, Chung W, Wu G, Egan S E and Xu K 2014 Tumor-suppressive activity of lunatic fringe in prostate through differential modulation of Notch receptor activation Neoplasia 16 158-67
-
(2014)
Neoplasia
, vol.16
, pp. 158-167
-
-
Zhang, S.1
Chung, W.2
Wu, G.3
Egan, S.E.4
Xu, K.5
-
57
-
-
77949484882
-
A role of receptor Notch in ligand cis-inhibition in Drosophila
-
Becam I, Fiuza U-M, Arias A M and Milán M 2010 A role of receptor Notch in ligand cis-inhibition in Drosophila Curr. Biol. 20 554-60
-
(2010)
Curr. Biol.
, vol.20
, pp. 554-560
-
-
Becam, I.1
Fiuza, U.-M.2
Arias, A.M.3
Milán, M.4
-
58
-
-
68849110194
-
Cis-inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition
-
Miller A C, Lyons E L and Herman T G 2009 Cis-inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition Curr. Biol. 19 1378-83
-
(2009)
Curr. Biol.
, vol.19
, pp. 1378-1383
-
-
Miller, A.C.1
Lyons, E.L.2
Herman, T.G.3
-
59
-
-
84866486422
-
Delta-like 1 and lateral inhibition during hair cell formation in the chicken inner ear: Evidence against cis-inhibition
-
Chrysostomou E, Gale J E and Daudet N 2012 Delta-like 1 and lateral inhibition during hair cell formation in the chicken inner ear: evidence against cis-inhibition Development 139 3764-74
-
(2012)
Development
, vol.139
, pp. 3764-3774
-
-
Chrysostomou, E.1
Gale, J.E.2
Daudet, N.3
-
60
-
-
84932604043
-
Cis-interactions between Notch and its ligands block ligand-independent Notch activity
-
Palmer W H, Jia D and Deng W-M 2015 Cis-interactions between Notch and its ligands block ligand-independent Notch activity eLife 3 e04415
-
(2015)
ELife
, vol.3
-
-
Palmer, W.H.1
Jia, D.2
Deng, W.-M.3
-
61
-
-
77957708340
-
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
-
Sheldon H et al 2010 New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes Blood 116 2385-94
-
(2010)
Blood
, vol.116
, pp. 2385-2394
-
-
Sheldon, H.1
-
62
-
-
84907853282
-
Modeling putative therapeutic implications of exosome exchange between tumor and immune cells
-
Lu M, Huang B, Hanash S M, Onuchic J N and Ben-Jacob E 2014 Modeling putative therapeutic implications of exosome exchange between tumor and immune cells Proc. Natl Acad. Sci. USA 111 E4165-74
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E4165-E4174
-
-
Lu, M.1
Huang, B.2
Hanash, S.M.3
Onuchic, J.N.4
Ben-Jacob, E.5
-
64
-
-
37049012486
-
Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo
-
Li J-L et al 2007 Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo Cancer Res. 67 11244-53
-
(2007)
Cancer Res.
, vol.67
, pp. 11244-11253
-
-
Li, J.-L.1
-
65
-
-
59649083306
-
Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells
-
Rosati E, Sabatini R, Rampino G, Tabilio A, Di Ianni M, Fettucciari K, Bartoli A, Coaccioli S, Screpanti I and Marconi P 2009 Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells Blood 113 856-65
-
(2009)
Blood
, vol.113
, pp. 856-865
-
-
Rosati, E.1
Sabatini, R.2
Rampino, G.3
Tabilio, A.4
Di Ianni, M.5
Fettucciari, K.6
Bartoli, A.7
Coaccioli, S.8
Screpanti, I.9
Marconi, P.10
-
66
-
-
84887273608
-
Epithelial plasticity: A common theme in embryonic and cancer cells
-
Nieto M A 2013 Epithelial plasticity: a common theme in embryonic and cancer cells. Science 342 1234850
-
(2013)
Science
, vol.342
-
-
Nieto, M.A.1
-
67
-
-
58149288656
-
Erk5 controls Slug expression and keratinocyte activation during wound healing
-
Arnoux V, Nassour M, Helgoualc A L, Hipskind R A and Savagner P 2008 Erk5 controls Slug expression and keratinocyte activation during wound healing Mol. Biol. Cell 19 4738-49
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4738-4749
-
-
Arnoux, V.1
Nassour, M.2
Helgoualc, A.L.3
Hipskind, R.A.4
Savagner, P.5
-
68
-
-
77954860342
-
Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression
-
Micalizzi D S, Farabaugh S M and Ford H L 2010 Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression J. Mammary Gland Biol. Neoplasia 15 117-34
-
(2010)
J. Mammary Gland Biol. Neoplasia
, vol.15
, pp. 117-134
-
-
Micalizzi, D.S.1
Farabaugh, S.M.2
Ford, H.L.3
-
69
-
-
68949155116
-
EMT 2.0: Shaping epithelia through collective migration
-
Revenu C and Gilmour D 2009 EMT 2.0: shaping epithelia through collective migration Curr. Opin. Genet. Dev. 19 338-42
-
(2009)
Curr. Opin. Genet. Dev.
, vol.19
, pp. 338-342
-
-
Revenu, C.1
Gilmour, D.2
-
70
-
-
43149112757
-
Involvement of notch signaling in wound healing
-
Chigurupati S et al 2007 Involvement of notch signaling in wound healing PLoS One 2 e1167
-
(2007)
PLoS One
, vol.2
-
-
Chigurupati, S.1
-
71
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
Yu M et al 2013 Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition Science 339 580-4
-
(2013)
Science
, vol.339
, pp. 580-584
-
-
Yu, M.1
-
72
-
-
84907342688
-
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
-
Aceto N et al 2014 Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis Cell 158 1110-22
-
(2014)
Cell
, vol.158
, pp. 1110-1122
-
-
Aceto, N.1
-
73
-
-
84867985453
-
Plasticity of disseminating cancer cells in patients with epithelial malignancies
-
Bednarz-Knoll N, Alix-Panabières C and Pantel K 2012 Plasticity of disseminating cancer cells in patients with epithelial malignancies Cancer Metastasis Rev. 31 673-87
-
(2012)
Cancer Metastasis Rev.
, vol.31
, pp. 673-687
-
-
Bednarz-Knoll, N.1
Alix-Panabières, C.2
Pantel, K.3
-
74
-
-
79951810835
-
Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells
-
Vallejo D M, Caparros E and Dominguez M 2011 Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells EMBO J. 30 756-69
-
(2011)
EMBO J.
, vol.30
, pp. 756-769
-
-
Vallejo, D.M.1
Caparros, E.2
Dominguez, M.3
-
75
-
-
84877263242
-
A microRNA miR-34a-regulated bimodal switch targets notch in colon cancer stem cells
-
Bu P et al 2013 A microRNA miR-34a-regulated bimodal switch targets notch in colon cancer stem cells Cell Stem Cell 12 602-15
-
(2013)
Cell Stem Cell
, vol.12
, pp. 602-615
-
-
Bu, P.1
-
76
-
-
77953920780
-
MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells
-
Pang R T, Leung C O, Ye T M, Liu W, Chiu P C, Lam K K, Lee K F and Yeung W S 2010 MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells Carcinogenesis 31 1037-44
-
(2010)
Carcinogenesis
, vol.31
, pp. 1037-1044
-
-
Pang, R.T.1
Leung, C.O.2
Ye, T.M.3
Liu, W.4
Chiu, P.C.5
Lam, K.K.6
Lee, K.F.7
Yeung, W.S.8
-
77
-
-
80052632447
-
MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133 + tumor-propagating cells and supports neural differentiation in medulloblastoma
-
De Antonellis P et al 2011 MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133 + tumor-propagating cells and supports neural differentiation in medulloblastoma PLoS One 6 e24584
-
(2011)
PLoS One
, vol.6
-
-
De Antonellis, P.1
-
78
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
Sahlgren C, Gustafsson M V, Jin S, Poellinger L and Lendahl U 2008 Notch signaling mediates hypoxia-induced tumor cell migration and invasion Proc. Natl Acad. Sci. USA 105 6392-7
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
79
-
-
48249103470
-
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
-
Niessen K, Fu Y, Chang L, Hoodless P A, McFadden D and Karsan A 2008 Slug is a direct Notch target required for initiation of cardiac cushion cellularization J. Cell Biol. 182 315-25
-
(2008)
J. Cell Biol.
, vol.182
, pp. 315-325
-
-
Niessen, K.1
Fu, Y.2
Chang, L.3
Hoodless, P.A.4
McFadden, D.5
Karsan, A.6
-
80
-
-
12944260524
-
Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes
-
Savagner P, Kusewitt D F, Carver E A, Magnino F, Choi C, Gridley T and Hudson L G 2005 Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes J. Cell. Physiol. 202 858-66
-
(2005)
J. Cell. Physiol.
, vol.202
, pp. 858-866
-
-
Savagner, P.1
Kusewitt, D.F.2
Carver, E.A.3
Magnino, F.4
Choi, C.5
Gridley, T.6
Hudson, L.G.7
-
81
-
-
34248209601
-
Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis
-
Leroy P and Mostov K E 2007 Slug is required for cell survival during partial epithelial-mesenchymal transition of HGF-induced tubulogenesis Mol. Biol. Cell 18 1943-52
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 1943-1952
-
-
Leroy, P.1
Mostov, K.E.2
-
82
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani S A et al 2008 The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 704-15
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
-
83
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel A-P, Lièvre M, Thomas C, Hinkal G, Ansieau S and Puisieux A 2008 Generation of breast cancer stem cells through epithelial-mesenchymal transition PLoS One 3 e2888
-
(2008)
PLoS One
, vol.3
-
-
Morel, A.-P.1
Lièvre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
Puisieux, A.6
-
84
-
-
84908154922
-
The EMT universe: Space between cancer cell dissemination and metastasis initiation
-
Ombrato L and Malanchi I 2014 The EMT universe: space between cancer cell dissemination and metastasis initiation Crit. Rev. Oncog. 19 349-61
-
(2014)
Crit. Rev. Oncog.
, vol.19
, pp. 349-361
-
-
Ombrato, L.1
Malanchi, I.2
-
85
-
-
84903768676
-
Tackling the cancer stem cells - What challenges do they pose?
-
Pattabiraman D R and Weinberg R A 2014 Tackling the cancer stem cells - what challenges do they pose? Nat. Rev. Drug Discovery 13 497-512
-
(2014)
Nat. Rev. Drug Discovery
, vol.13
, pp. 497-512
-
-
Pattabiraman, D.R.1
Weinberg, R.A.2
-
86
-
-
84880320134
-
Evidence for a common progenitor of epithelial and mesenchymal components of the liver
-
Conigliaro A et al 2013 Evidence for a common progenitor of epithelial and mesenchymal components of the liver Cell Death Differ. 20 1116-23
-
(2013)
Cell Death Differ.
, vol.20
, pp. 1116-1123
-
-
Conigliaro, A.1
-
87
-
-
79251540883
-
Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity
-
Strauss R et al 2011 Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity PLoS One 6 e16186
-
(2011)
PLoS One
, vol.6
-
-
Strauss, R.1
-
88
-
-
76749112922
-
NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer
-
Sikandar S S, Pate K T, Anderson S, Dizon D, Edwards R A, Waterman M L and Lipkin S M 2010 NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer Cancer Res. 70 1469-78
-
(2010)
Cancer Res.
, vol.70
, pp. 1469-1478
-
-
Sikandar, S.S.1
Pate, K.T.2
Anderson, S.3
Dizon, D.4
Edwards, R.A.5
Waterman, M.L.6
Lipkin, S.M.7
-
89
-
-
80052795862
-
Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
-
Zhu T S et al 2011 Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells Cancer Res. 71 6061-72
-
(2011)
Cancer Res.
, vol.71
, pp. 6061-6072
-
-
Zhu, T.S.1
-
90
-
-
65549141305
-
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway
-
Wang Z, Li Y, Kong D, Banerjee S, Ahmad A, Azmi A S, Ali S, Abbruzzese J L, Gallick G E and Sarkar F H 2009 Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway Cancer Res. 69 2400-7
-
(2009)
Cancer Res.
, vol.69
, pp. 2400-2407
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Banerjee, S.4
Ahmad, A.5
Azmi, A.S.6
Ali, S.7
Abbruzzese, J.L.8
Gallick, G.E.9
Sarkar, F.H.10
-
91
-
-
84864026866
-
Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy
-
Kamdje A H N, Bassi G, Pacelli L, Malpeli G, Amati E, Nichele I, Pizzolo G and Krampera R 2012 Role of stromal cell-mediated Notch signaling in CLL resistance to chemotherapy Blood Cancer J. 2 e73
-
(2012)
Blood Cancer J.
, vol.2
, pp. e73
-
-
Kamdje, A.H.N.1
Bassi, G.2
Pacelli, L.3
Malpeli, G.4
Amati, E.5
Nichele, I.6
Pizzolo, G.7
Krampera, R.8
-
92
-
-
41349095228
-
Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy
-
Nefedova Y, Sullivan D M, Bolick S C, Dalton W S and Gabrilovich D I 2008 Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy Blood 111 2220-9
-
(2008)
Blood
, vol.111
, pp. 2220-2229
-
-
Nefedova, Y.1
Sullivan, D.M.2
Bolick, S.C.3
Dalton, W.S.4
Gabrilovich, D.I.5
-
93
-
-
79952121979
-
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
-
Iliopoulos D, Hirsch H A, Wang G and Struhl K 2011 Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion Proc. Natl Acad. Sci. USA 108 1397-402
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 1397-1402
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Wang, G.3
Struhl, K.4
-
94
-
-
84864087971
-
TNF enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells
-
Lee S H, Hong H S, Liu Z X, Kim R H, Kang M K, Park N-H and Shin K-H 2012 TNF enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells Biochem. Biophys. Res. Commun. 424 58-64
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.424
, pp. 58-64
-
-
Lee, S.H.1
Hong, H.S.2
Liu, Z.X.3
Kim, R.H.4
Kang, M.K.5
Park, N.-H.6
Shin, K.-H.7
-
95
-
-
84879731392
-
The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis
-
Chang Q et al 2013 The IL-6/JAK/Stat3 feed-forward loop drives tumorigenesis and metastasis Neoplasia 15 848-62
-
(2013)
Neoplasia
, vol.15
, pp. 848-862
-
-
Chang, Q.1
-
96
-
-
84883193749
-
Nonlinear growth kinetics of breast cancer stem cells: Implications for cancer stem cell targeted therapy
-
Liu X et al 2013 Nonlinear growth kinetics of breast cancer stem cells: implications for cancer stem cell targeted therapy Sci. Rep. 3 2473
-
(2013)
Sci. Rep.
, vol.3
, pp. 2473
-
-
Liu, X.1
-
97
-
-
84906972436
-
A mathematical-biological joint effort to investigate the tumor-initiating ability of cancer stem cells
-
Fornari C, Beccuti M, Lanzardo S, Conti L, Balbo G, Cavallo F, Calogero R A and Cordero F 2014 A mathematical-biological joint effort to investigate the tumor-initiating ability of cancer stem cells PLoS One 9 e106193
-
(2014)
PLoS One
, vol.9
-
-
Fornari, C.1
Beccuti, M.2
Lanzardo, S.3
Conti, L.4
Balbo, G.5
Cavallo, F.6
Calogero, R.A.7
Cordero, F.8
-
98
-
-
84901399936
-
A multi-phenotypic cancer model with cell plasticity
-
Zhou D, Wang Y and Wu B 2014 A multi-phenotypic cancer model with cell plasticity J. Theor. Biol. 357 35-45
-
(2014)
J. Theor. Biol.
, vol.357
, pp. 35-45
-
-
Zhou, D.1
Wang, Y.2
Wu, B.3
-
99
-
-
77954621247
-
Investigating the link between epithelial-mesenchymal transition and the cancer stem cell phenotype: A mathematical approach
-
Turner C and Kohandel M 2010 Investigating the link between epithelial-mesenchymal transition and the cancer stem cell phenotype: a mathematical approach J. Theor. Biol. 265 329-35
-
(2010)
J. Theor. Biol.
, vol.265
, pp. 329-335
-
-
Turner, C.1
Kohandel, M.2
-
100
-
-
84865798159
-
Bacterial survival strategies suggest rethinking cancer cooperativity
-
Ben-Jacob E, Coffey D S and Levine H 2012 Bacterial survival strategies suggest rethinking cancer cooperativity Trends Microbiol. 20 403-10
-
(2012)
Trends Microbiol.
, vol.20
, pp. 403-410
-
-
Ben-Jacob, E.1
Coffey, D.S.2
Levine, H.3
|